Amir A Saei

Affiliations

Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.
Division of Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, SE-17 177, Sweden.
Biozentrum, University of Basel, Basel, 4056, Switzerland.
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 17165, Sweden.

Publications (36)

Crosstalk between P53 and DNA damage response in ageing.

DNA repair

Avec: Amir Mohammadzadeh , Mohammad Mirza-Aghazadeh-Attari , Shahin Hallaj , Amir Ata Saei , Mohammad Reza Alivand , Amir Valizadeh , Bahman Yousefi , Maryam Majidinia

Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation.

Cancer letters

Avec: Ellin-Kristina Hillert , Slavica Brnjic , Xiaonan Zhang , Magdalena Mazurkiewicz , Amir Ata Saei , Arjan Mofers , Karthik Selvaraju , Roman Zubarev , Stig Linder , Padraig D'Arcy

Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels.

ACS applied bio materials

Avec: Shahriar Sharifi , Amir Ata Saei , Hassan Gharibi , Nouf N Mahmoud , Shannon Harkins , Naruphorn Dararatana , Erika M Lisabeth , Vahid Serpooshan , Ákos Végvári , Anna Moore , Morteza Mahmoudi

Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds.

Cancer research

Avec: Sylvain Peuget , Jiawei Zhu , Gema Sanz , Madhurendra Singh , Massimiliano Gaetani , Xinsong Chen , Yao Shi , Amir Ata Saei , Torkild Visnes , Mikael S Lindström , Ali Rihani , Lidia Moyano-Galceran , Joseph W Carlson , Elisabet Hjerpe , Ulrika Joneborg , Kaisa Lehti , Johan Hartman , Thomas Helleday , Roman Zubarev , Galina Selivanova

ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery.

Nature communications

Avec: Amir Ata Saei , Christian Michel Beusch , Alexey Chernobrovkin , Pierre Sabatier , Bo Zhang , Ülkü Güler Tokat , Eleni Stergiou , Massimiliano Gaetani , Ákos Végvári , Roman A Zubarev

Immunotargeting and therapy of cancer by advanced multivalence antibody scaffolds.

Journal of drug targeting

Avec: Vala Kafil , Amir Ata Saei , Mohammad Reza Tohidkia , Jaleh Barar , Yadollah Omidi

DNA damage response and repair in ovarian cancer: Potential targets for therapeutic strategies.

DNA repair

Avec: Mohammad Mirza-Aghazadeh-Attari , Caspian Ostadian , Amir Ata Saei , Ainaz Mihanfar , Saber Ghazizadeh Darband , Shirin Sadighparvar , Mojtaba Kaviani , Hossein Samadi Kafil , Bahman Yousefi , Maryam Majidinia

Massive Solubility Changes in Neuronal Proteins upon Simulated Traumatic Brain Injury Reveal the Role of Shockwaves in Irreversible Damage.

Molecules (Basel, Switzerland)

Avec: Amir Ata Saei , Hassan Gharibi , Hezheng Lyu , Brady Nilsson , Maryam Jafari , Hans Von Holst , Roman A Zubarev

Multifaceted Proteome Analysis at Solubility, Redox, and Expression Dimensions for Target Identification.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Albin Lundin , Hezheng Lyu , Hassan Gharibi , Huqiao Luo , Jaakko Teppo , Xuepei Zhang , Massimiliano Gaetani , Ákos Végvári , Rikard Holmdahl , Steven P Gygi , Roman A Zubarev

Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution.

Journal of proteome research

Avec: Massimiliano Gaetani , Pierre Sabatier , Christian M Beusch , Zhe Yang , Susanna L Lundström , Roman A Zubarev

Abnormal (Hydroxy)proline Deuterium Content Redefines Hydrogen Chemical Mass.

Journal of the American Chemical Society

Avec: Hassan Gharibi , Alexey L Chernobrovkin , Gunilla Eriksson , Amir Ata Saei , Zena Timmons , Andrew C Kitchener , Daniela C Kalthoff , Kerstin Lidén , Alexander A Makarov , Roman A Zubarev

A uniform data processing pipeline enables harmonized nanoparticle protein corona analysis across proteomics core facilities.

Nature communications

Avec: Hassan Gharibi , Ali Akbar Ashkarran , Maryam Jafari , Elizabeth Voke , Markita P Landry , Amir Ata Saei , Morteza Mahmoudi

Proteomics-Compatible Fourier Transform Isotopic Ratio Mass Spectrometry of Polypeptides.

Analytical chemistry

Avec: Hassan Gharibi , Alexey L Chernobrovkin , Amir Ata Saei , Xuepei Zhang , Massimiliano Gaetani , Alexander A Makarov , Roman A Zubarev

First Experimental Evidence for Reversibility of Ammonia Loss from Asparagine.

International journal of molecular sciences

Avec: Jijing Wang , Sergey Rodin , Amir Ata Saei , Xuepei Zhang , Roman A Zubarev

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

JCI insight

Avec: Huqiao Luo , Vilma Urbonaviciute , Amir Ata Saei , Hezheng Lyu , Massimiliano Gaetani , Ákos Végvári , Yanpeng Li , Roman A Zubarev , Rikard Holmdahl

Ultralight Ultrafast Enzymes.

Angewandte Chemie (International ed. in English)

Avec: Xuepei Zhang , Zhaowei Meng , Christian M Beusch , Hassan Gharibi , Qing Cheng , Hezheng Lyu , Luciano Di Stefano , Jijing Wang , Ákos Végvári , Massimiliano Gaetani , Roman A Zubarev

Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates.

Analytical chemistry

Avec: Zhaowei Meng , Amir Ata Saei , Hassan Gharibi , Xuepei Zhang , Hezheng Lyu , Susanna L Lundström , Ákos Végvári , Massimiliano Gaetani , Roman A Zubarev

Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin.

Redox biology

Avec: Amir Ata Saei , Hjalmar Gullberg , Pierre Sabatier , Christian M Beusch , Katarina Johansson , Bo Lundgren , Per I Arvidsson , Elias S J Arnér , Roman A Zubarev

Nanotechnology for Targeted Detection and Removal of Bacteria: Opportunities and Challenges.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Mohammad J Hajipour , Amir Ata Saei , Edward D Walker , Brian Conley , Yadollah Omidi , Ki-Bum Lee , Morteza Mahmoudi

An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation.

Nature communications

Avec: Pierre Sabatier , Christian M Beusch , Mike Aoun , Noah Moruzzi , Ana Coelho , Niels Leijten , Magnus Nordenskjöld , Patrick Micke , Diana Maltseva , Alexander G Tonevitsky , Vincent Millischer , J Carlos Villaescusa , Sandeep Kadekar , Massimiliano Gaetani , Kamilya Altynbekova , Alexander Kel , Per-Olof Berggren , Oscar Simonson , Karl-Henrik Grinnemo , Rikard Holmdahl , Sergey Rodin , Roman A Zubarev

Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation.

eLife

Avec: Jaime James , Yifei Chen , Clara M Hernandez , Florian Forster , Markus Dagnell , Qing Cheng , Hassan Gharibi , Gonzalo Fernandez Lahore , Annika Åstrand , Rajneesh Malhotra , Bernard Malissen , Roman A Zubarev , Elias S J Arnér , Rikard Holmdahl

Multi-omics analysis of magnetically levitated plasma biomolecules.

Biosensors & bioelectronics

Avec: Ali Akbar Ashkarran , Hassan Gharibi , Dalia Abou Zeki , Irina Radu , Farnaz Khalighinejad , Kiandokht Keyhanian , Christoffer K Abrahamsson , Carolina Ionete , Amir Ata Saei , Morteza Mahmoudi

Sex-Specific Silica Nanoparticle Protein Corona Compositions Exposed to Male and Female BALB/c Mice Plasmas.

ACS bio & med chem Au

Avec: Ali Akbar Ashkarran , Hassan Gharibi , Jason W Grunberger , Amir Ata Saei , Nitish Khurana , Raziye Mohammadpour , Hamidreza Ghandehari , Morteza Mahmoudi

Chemical Proteomics Reveals that the Anticancer Drug Everolimus Affects the Ubiquitin-Proteasome System.

ACS pharmacology & translational science

Avec: Anna A Lobas , Amir Ata Saei , Hezheng Lyu , Roman A Zubarev , Mikhail V Gorshkov

Standardizing Protein Corona Characterization in Nanomedicine: A Multicenter Study to Enhance Reproducibility and Data Homogeneity.

Nano letters

Avec: Ali Akbar Ashkarran , Hassan Gharibi , Seyed Majed Modaresi , Amir Ata Saei , Morteza Mahmoudi

COVID-19: Nanomedicine Uncovers Blood-Clot Mystery.

Journal of proteome research

Avec: Amir Ata Saei , Shahriar Sharifi , Morteza Mahmoudi

Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment.

Oxidative medicine and cellular longevity

Avec: Xiaonan Zhang , Belén Espinosa , Amir Ata Saei , Padraig D'Arcy , Roman A Zubarev , Stig Linder

Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug.

Biochimie

Avec: Xiaonan Zhang , Karthik Selvaraju , Amir Ata Saei , Padraig D'Arcy , Roman A Zubarev , Elias Sj Arnér , Stig Linder

Predictive Biomarker Panel in Proliferative Lupus Nephritis- Two-Dimensional Shotgun Proteomics.

Iranian journal of kidney diseases

Avec: Mohsen Ghasemi , Shiva Kalantari , Roman A Zubarev , Mohsen Nafar , Amir Ata Saei , Somaye-Sadat Heidari , Ahmad Reza Baghestani , Shiva Samavat

Breathomics: Review of Sample Collection and Analysis, Data Modeling and Clinical Applications.

Critical reviews in analytical chemistry

Avec: Maryam Khoubnasabjafari , Mohamad Reza Afshar Mogaddam , Elaheh Rahimpour , Jafar Soleymani , Amir Ata Saei , Abolghasem Jouyban

Can the biomolecular corona induce an allergic reaction?-A proof-of-concept study.

Biointerphases

Avec: Anne Muehe , Hossein Nejadnik , Henrik Muehe , Jarrett Rosenberg , Hassan Gharibi , Amir Ata Saei , Shu-Chen Lyu , Kari C Nadeau , Morteza Mahmoudi , Heike E Daldrup-Link

System-wide identification and prioritization of enzyme substrates by thermal analysis.

Nature communications

Avec: Amir Ata Saei , Christian M Beusch , Pierre Sabatier , Juan Astorga Wells , Hassan Gharibi , Zhaowei Meng , Alexey Chernobrovkin , Sergey Rodin , Katja Näreoja , Ann-Gerd Thorsell , Tobias Karlberg , Qing Cheng , Susanna L Lundström , Massimiliano Gaetani , Ákos Végvári , Elias S J Arnér , Herwig Schüler , Roman A Zubarev

Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities.

Nature communications

Avec: Ali Akbar Ashkarran , Hassan Gharibi , Elizabeth Voke , Markita P Landry , Amir Ata Saei , Morteza Mahmoudi

Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules.

bioRxiv : the preprint server for biology

Avec: Ali Akbar Ashkarran , Hassan Gharibi , Seyed Majed Modaresi , Maryam Sayadi , Maryam Jafari , Zijin Lin , Danilo Ritz , David Kakhniashvili , Liangliang Sun , Markita P Landry , Amir Ata Saei , Morteza Mahmoudi

Adding Color to Mass Spectra of Biopolymers: Charge Determination Analysis (CHARDA) Assigns Charge State to Every Ion Peak.

Journal of the American Society for Mass Spectrometry

Avec: Yaroslav Lyutvinskiy , Konstantin O Nagornov , Anton N Kozhinov , Natalia Gasilova , Laure Menin , Zhaowei Meng , Xuepei Zhang , Amir Ata Saei , Tingting Fu , Julia Chamot-Rooke , Yury O Tsybin , Alexander Makarov , Roman A Zubarev

The role of protein corona in advancing plasma proteomics.

Proteomics

Avec: Amir Ata Saei , Liangliang Sun , Morteza Mahmoudi

Réseau de co-auteurs

Amir Ata Saei 31 collaborations

Roman A Zubarev 19 collaborations

Hassan Gharibi 16 collaborations

Morteza Mahmoudi 11 collaborations

Massimiliano Gaetani 10 collaborations

Ákos Végvári 7 collaborations

Hezheng Lyu 6 collaborations

Xuepei Zhang 6 collaborations

Ali Akbar Ashkarran 6 collaborations

Pierre Sabatier 5 collaborations

Christian M Beusch 5 collaborations

Rikard Holmdahl 4 collaborations

Zhaowei Meng 4 collaborations

Xiaonan Zhang 3 collaborations

Stig Linder 3 collaborations

Padraig D'Arcy 3 collaborations

Maryam Jafari 3 collaborations

Susanna L Lundström 3 collaborations

Markita P Landry 3 collaborations

Sergey Rodin 3 collaborations

Qing Cheng 3 collaborations

Elias S J Arnér 3 collaborations

Mohammad Mirza-Aghazadeh-Attari 2 collaborations

Bahman Yousefi 2 collaborations

Maryam Majidinia 2 collaborations

Karthik Selvaraju 2 collaborations

Roman Zubarev 2 collaborations

Shahriar Sharifi 2 collaborations

Alexey Chernobrovkin 2 collaborations

Yadollah Omidi 2 collaborations

Huqiao Luo 2 collaborations

Alexey L Chernobrovkin 2 collaborations

Alexander A Makarov 2 collaborations

Elizabeth Voke 2 collaborations

Jijing Wang 2 collaborations

Seyed Majed Modaresi 2 collaborations

Liangliang Sun 2 collaborations

Amir Mohammadzadeh 1 collaboration

Shahin Hallaj 1 collaboration

Mohammad Reza Alivand 1 collaboration

Amir Valizadeh 1 collaboration

Ellin-Kristina Hillert 1 collaboration

Slavica Brnjic 1 collaboration

Magdalena Mazurkiewicz 1 collaboration

Arjan Mofers 1 collaboration

Nouf N Mahmoud 1 collaboration

Shannon Harkins 1 collaboration

Naruphorn Dararatana 1 collaboration

Erika M Lisabeth 1 collaboration

Vahid Serpooshan 1 collaboration

Anna Moore 1 collaboration

Sylvain Peuget 1 collaboration

Jiawei Zhu 1 collaboration

Gema Sanz 1 collaboration

Madhurendra Singh 1 collaboration

Xinsong Chen 1 collaboration

Yao Shi 1 collaboration

Torkild Visnes 1 collaboration

Mikael S Lindström 1 collaboration

Ali Rihani 1 collaboration

Lidia Moyano-Galceran 1 collaboration

Joseph W Carlson 1 collaboration

Elisabet Hjerpe 1 collaboration

Ulrika Joneborg 1 collaboration

Kaisa Lehti 1 collaboration

Johan Hartman 1 collaboration

Thomas Helleday 1 collaboration

Galina Selivanova 1 collaboration

Christian Michel Beusch 1 collaboration

Bo Zhang 1 collaboration

Ülkü Güler Tokat 1 collaboration

Eleni Stergiou 1 collaboration

Vala Kafil 1 collaboration

Mohammad Reza Tohidkia 1 collaboration

Jaleh Barar 1 collaboration

Caspian Ostadian 1 collaboration

Ainaz Mihanfar 1 collaboration

Saber Ghazizadeh Darband 1 collaboration

Shirin Sadighparvar 1 collaboration

Mojtaba Kaviani 1 collaboration

Hossein Samadi Kafil 1 collaboration

Brady Nilsson 1 collaboration

Hans Von Holst 1 collaboration

Albin Lundin 1 collaboration

Jaakko Teppo 1 collaboration

Steven P Gygi 1 collaboration

Zhe Yang 1 collaboration

Gunilla Eriksson 1 collaboration

Zena Timmons 1 collaboration

Andrew C Kitchener 1 collaboration

Daniela C Kalthoff 1 collaboration

Kerstin Lidén 1 collaboration

Vilma Urbonaviciute 1 collaboration

Yanpeng Li 1 collaboration

Luciano Di Stefano 1 collaboration

Hjalmar Gullberg 1 collaboration

Katarina Johansson 1 collaboration

Bo Lundgren 1 collaboration

Per I Arvidsson 1 collaboration

Mohammad J Hajipour 1 collaboration

Edward D Walker 1 collaboration

Brian Conley 1 collaboration

Ki-Bum Lee 1 collaboration

Mike Aoun 1 collaboration

Noah Moruzzi 1 collaboration

Ana Coelho 1 collaboration

Niels Leijten 1 collaboration

Magnus Nordenskjöld 1 collaboration

Patrick Micke 1 collaboration

Diana Maltseva 1 collaboration

Alexander G Tonevitsky 1 collaboration

Vincent Millischer 1 collaboration

J Carlos Villaescusa 1 collaboration

Sandeep Kadekar 1 collaboration

Kamilya Altynbekova 1 collaboration

Alexander Kel 1 collaboration

Per-Olof Berggren 1 collaboration

Oscar Simonson 1 collaboration

Karl-Henrik Grinnemo 1 collaboration

Jaime James 1 collaboration

Yifei Chen 1 collaboration

Clara M Hernandez 1 collaboration

Florian Forster 1 collaboration

Markus Dagnell 1 collaboration

Gonzalo Fernandez Lahore 1 collaboration

Annika Åstrand 1 collaboration

Rajneesh Malhotra 1 collaboration

Bernard Malissen 1 collaboration

Dalia Abou Zeki 1 collaboration

Irina Radu 1 collaboration

Farnaz Khalighinejad 1 collaboration

Kiandokht Keyhanian 1 collaboration

Christoffer K Abrahamsson 1 collaboration

Carolina Ionete 1 collaboration

Jason W Grunberger 1 collaboration

Nitish Khurana 1 collaboration

Raziye Mohammadpour 1 collaboration

Hamidreza Ghandehari 1 collaboration

Anna A Lobas 1 collaboration

Mikhail V Gorshkov 1 collaboration

Belén Espinosa 1 collaboration

Elias Sj Arnér 1 collaboration

Mohsen Ghasemi 1 collaboration

Shiva Kalantari 1 collaboration

Mohsen Nafar 1 collaboration

Somaye-Sadat Heidari 1 collaboration

Ahmad Reza Baghestani 1 collaboration

Shiva Samavat 1 collaboration

Maryam Khoubnasabjafari 1 collaboration

Mohamad Reza Afshar Mogaddam 1 collaboration

Elaheh Rahimpour 1 collaboration

Jafar Soleymani 1 collaboration

Abolghasem Jouyban 1 collaboration

Anne Muehe 1 collaboration

Hossein Nejadnik 1 collaboration

Henrik Muehe 1 collaboration

Jarrett Rosenberg 1 collaboration

Shu-Chen Lyu 1 collaboration

Kari C Nadeau 1 collaboration

Heike E Daldrup-Link 1 collaboration

Juan Astorga Wells 1 collaboration

Katja Näreoja 1 collaboration

Ann-Gerd Thorsell 1 collaboration

Tobias Karlberg 1 collaboration

Herwig Schüler 1 collaboration

Maryam Sayadi 1 collaboration

Zijin Lin 1 collaboration

Danilo Ritz 1 collaboration

David Kakhniashvili 1 collaboration

Yaroslav Lyutvinskiy 1 collaboration

Konstantin O Nagornov 1 collaboration

Anton N Kozhinov 1 collaboration

Natalia Gasilova 1 collaboration

Laure Menin 1 collaboration

Tingting Fu 1 collaboration

Julia Chamot-Rooke 1 collaboration

Yury O Tsybin 1 collaboration

Alexander Makarov 1 collaboration