Chahrazed Bouzriba

Affiliations

Centre de recherche du CHU de Québec-Université Laval, Axe Oncologie, Hôpital Saint-François d'Assise, 10 rue de l'Espinay, Québec, QC G1L 3L5, Canada; Faculté de pharmacie, Université Laval, Pavillon Ferdinand-Vandry, 1050 avenue de la Médecine, Québec, QC G1V 0A6, Canada. Electronic address: chahrazed.bouzriba.1@ulaval.ca.

Publications (11)

Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.

Bioorganic & medicinal chemistry letters

Avec: Vincent Ouellette , Chahrazed Bouzriba , Atziri Corin Chavez Alvarez , Geneviève Hamel-Côté , Sébastien Fortin

N-phenyl ureidobenzenesulfonates, a novel class of promising human dihydroorotate dehydrogenase inhibitors.

Bioorganic & medicinal chemistry

Avec: Chahrazed Bouzriba , Lauriane Larcher , Mathieu Gagné-Boulet , Sébastien Fortin

Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells.

RSC medicinal chemistry

Avec: Vincent Ouellette , Chahrazed Bouzriba , Atziri Corin Chavez Alvarez , Quentin Bruxelles , Geneviève Hamel-Côté , Sébastien Fortin

Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.

European journal of medicinal chemistry

Avec: Mathieu Gagné-Boulet , Chahrazed Bouzriba , Atziri Corin Chavez Alvarez , Sébastien Fortin

Branched alkyl of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as unique cytochrome P450 1A1-activated antimitotic prodrugs: Biological evaluation and mechanism of bioactivation.

European journal of medicinal chemistry

Avec: Chahrazed Bouzriba , Atziri Corin Chavez Alvarez , Mathieu Gagné-Boulet , Vincent Ouellette , Jacques Lacroix , Marie-France Côté , René C-Gaudreault , Sébastien Fortin

4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamide salts: Novel hydrosoluble prodrugs of antimitotics selectively bioactivated by the cytochrome P450 1A1 in breast cancer cells.

Bioorganic chemistry

Avec: Vincent Ouellette , Atziri Corin Chavez Alvarez , Chahrazed Bouzriba , Geneviève Hamel-Côté , Sébastien Fortin

Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents.

Bioorganic chemistry

Avec: Chahrazed Bouzriba , Mathieu Gagné-Boulet , Atziri Corin Chavez Alvarez , Vincent Ouellette , Isabelle Laverdière , Sébastien Fortin

Stereoselective Synthesis of Fluorinated Galactopyranosides as Potential Molecular Probes for Galactophilic Proteins: Assessment of Monofluorogalactoside-LecA Interactions.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Vincent Denavit , Danny Lainé , Chahrazed Bouzriba , Elena Shanina , Émilie Gillon , Sébastien Fortin , Christoph Rademacher , Anne Imberty , Denis Giguère

Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates.

Chemical biology & drug design

Avec: Mathieu Gagné-Boulet , Chahrazed Bouzriba , Atziri Corin Chavez Alvarez , Sébastien Fortin

Homologation of the Alkyl Side Chain of Antimitotic Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonate Prodrugs Selectively Targeting CYP1A1-Expressing Breast Cancers Improves Their Stability in Rodent Liver Microsomes.

Journal of medicinal chemistry

Avec: Atziri Corin Chavez Alvarez , Chahrazed Bouzriba , Emmanuel Moreau , Philippe Auzeloux , Sophie Besse , Vincent Ouellette , Mitra Zarifi Khosroshahi , Marie-France Côté , Sylvie Pilote , Elisabeth Miot-Noirault , Jean-Michel Chezal , Chantale Simard , René C-Gaudreault , Sébastien Fortin

Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups.

Steroids

Avec: Alexis Paquin , Fayanne Nolin , Chahrazed Bouzriba , Sébastien Fortin , Irina F Sevrioukova , Gervais Bérubé

Réseau de co-auteurs

Sébastien Fortin 11 collaborations

Atziri Corin Chavez Alvarez 8 collaborations

Vincent Ouellette 6 collaborations

Mathieu Gagné-Boulet 5 collaborations

Geneviève Hamel-Côté 3 collaborations

Marie-France Côté 2 collaborations

René C-Gaudreault 2 collaborations

Lauriane Larcher 1 collaboration

Quentin Bruxelles 1 collaboration

Jacques Lacroix 1 collaboration

Isabelle Laverdière 1 collaboration

Vincent Denavit 1 collaboration

Danny Lainé 1 collaboration

Elena Shanina 1 collaboration

Émilie Gillon 1 collaboration

Christoph Rademacher 1 collaboration

Anne Imberty 1 collaboration

Denis Giguère 1 collaboration

Emmanuel Moreau 1 collaboration

Philippe Auzeloux 1 collaboration

Sophie Besse 1 collaboration

Mitra Zarifi Khosroshahi 1 collaboration

Sylvie Pilote 1 collaboration

Elisabeth Miot-Noirault 1 collaboration

Jean-Michel Chezal 1 collaboration

Chantale Simard 1 collaboration

Alexis Paquin 1 collaboration

Fayanne Nolin 1 collaboration

Irina F Sevrioukova 1 collaboration

Gervais Bérubé 1 collaboration