Andrei V Gudkov

Affiliations

Roswell Park Comprehensive Cancer Center, Elm and Carlton streets, Buffalo, NY, USA.
Genome Protection, Inc., Buffalo, NY, USA.

ORCID: http://orcid.org/0000-0003-2548-0154

Publications (20)

Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit.

Nature communications

Avec: Timothy V Pyrkov , Konstantin Avchaciov , Andrei E Tarkhov , Leonid I Menshikov , Andrei V Gudkov , Peter O Fedichev

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients.

Oncotarget

Avec: Natalia V Eremina , Vasily I Kazey , Sergey V Mishugin , Roman V Leonenkov , Dmitry Y Pushkar , Vadim L Mett , Andrei V Gudkov

Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo.

Free radical biology & medicine

Avec: Suvranil Ghosh , Naibedya Dutta , Pinaki Banerjee , Rahul L Gajbhiye , Hossainoor Rahaman Sareng , Prachi Kapse , Srabani Pal , Lyudmila Burdelya , Narayan C Mandal , Velyutham Ravichandiran , Ashish Bhattacharjee , Gopal C Kundu , Andrei V Gudkov , Mahadeb Pal

Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules.

Methods in molecular biology (Clifton, N.J.)

Avec: Catherine A Burkhart , Michelle Haber , Murray D Norris , Andrei V Gudkov , Mikhail A Nikiforov

Signaling through TLR5 mitigates lethal radiation damage by neutrophil-dependent release of MMP-9.

Cell death discovery

Avec: Craig M Brackett , Kellee F Greene , Alyssa R Aldrich , Nicholas H Trageser , Srabani Pal , Ivan Molodtsov , Bojidar M Kandar , Lyudmila G Burdelya , Scott I Abrams , Andrei V Gudkov

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer.

Oncotarget

Avec: Marina P Antoch , Michelle Wrobel , Bryan Gillard , Karen K Kuropatwinski , Ilia Toshkov , Anatoli S Gleiberman , Ellen Karasik , Michael T Moser , Barbara A Foster , Ekaterina L Andrianova , Olga V Chernova , Andrei V Gudkov

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.

Cell metabolism

Avec: Matthew Simon , Michael Van Meter , Julia Ablaeva , Zhonghe Ke , Raul S Gonzalez , Taketo Taguchi , Marco De Cecco , Katerina I Leonova , Valeria Kogan , Stephen L Helfand , Nicola Neretti , Asael Roichman , Haim Y Cohen , Margarita V Meer , Vadim N Gladyshev , Marina P Antoch , Andrei V Gudkov , John M Sedivy , Andrei Seluanov , Vera Gorbunova

Cells exhibiting strong

Proceedings of the National Academy of Sciences of the United States of America

Avec: Jie-Yu Liu , George P Souroullas , Brian O Diekman , Janakiraman Krishnamurthy , Brandon M Hall , Jessica A Sorrentino , Joel S Parker , Garrett A Sessions , Andrei V Gudkov , Norman E Sharpless

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.

Cell reports

Avec: Anahid Ehteda , Sandy Simon , Laura Franshaw , Federico M Giorgi , Jie Liu , Swapna Joshi , Jourdin R C Rouaen , Chi Nam Ignatius Pang , Ruby Pandher , Chelsea Mayoh , Yujie Tang , Aaminah Khan , Caitlin Ung , Ornella Tolhurst , Anne Kankean , Elisha Hayden , Rebecca Lehmann , Sylvie Shen , Anjana Gopalakrishnan , Peter Trebilcock , Katerina Gurova , Andrei V Gudkov , Murray D Norris , Michelle Haber , Orazio Vittorio , Maria Tsoli , David S Ziegler

FACT inhibitor CBL0137, administered in an optimized schedule, potentiates radiation therapy for glioblastoma by suppressing DNA damage repair.

Journal of neuro-oncology

Avec: Tara A Barone , Denisha L Robinson , Jingxin Qiu , Katerina V Gurova , Andrei A Purmal , Andrei V Gudkov , Robert J Plunkett

TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects.

PloS one

Avec: Gary J Haderski , Bojidar M Kandar , Craig M Brackett , Ilia M Toshkov , Christopher P Johnson , Geraldine M Paszkiewicz , Venkatesh Natarajan , Anatoli S Gleiberman , Andrei V Gudkov , Lyudmila G Burdelya

OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis.

Leukemia

Avec: Lioubov Korotchkina , Denis Kazyulkin , Pavel G Komarov , Alex Polinsky , Ekaterina L Andrianova , Sangeeta Joshi , Mahima Gupta , Slavoljub Vujcic , Eugene Kononov , Ilia Toshkov , Yuan Tian , Peter Krasnov , Mikhail V Chernov , Jean Veith , Marina P Antoch , Shiloh Middlemiss , Klaartje Somers , Richard B Lock , Murray D Norris , Michelle J Henderson , Michelle Haber , Olga B Chernova , Andrei V Gudkov

Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.

Nucleic acids research

Avec: Ian Miller , Max Totrov , Lioubov Korotchkina , Denis N Kazyulkin , Andrei V Gudkov , Sergey Korolev

Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Ksenia A Novototskaya-Vlasova , Nickolay S Neznanov , Ivan Molodtsov , Brandon M Hall , Mairead Commane , Anatoli S Gleiberman , Jayne Murray , Michelle Haber , Murray D Norris , Katerina I Leonova , Andrei V Gudkov

Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans.

Cancer research communications

Avec: Alexandra V Vylegzhanina , Ivan A Bespalov , Ksenia A Novototskaya-Vlasova , Brandon M Hall , Anatoli S Gleiberman , Han Yu , Olga V Leontieva , Katerina I Leonova , Oleg V Kurnasov , Andrei L Osterman , Grace K Dy , Alexey A Komissarov , Elena Vasilieva , Jeff Gehlhausen , Akiko Iwasaki , Christine B Ambrosone , Takemasa Tsuji , Junko Matsuzaki , Kunle Odunsi , Ekaterina L Andrianova , Andrei V Gudkov

Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue.

Aging cell

Avec: Brandon M Hall , Anatoli S Gleiberman , Evguenia Strom , Peter A Krasnov , David Frescas , Slavoljub Vujcic , Olga V Leontieva , Marina P Antoch , Valeria Kogan , Igor E Koman , Yi Zhu , Tamara Tchkonia , James L Kirkland , Olga B Chernova , Andrei V Gudkov

Latest advances in aging research and drug discovery.

Aging

Avec: Daniela Bakula , Andrea Ablasser , Adriano Aguzzi , Adam Antebi , Nir Barzilai , Martin-Immanuel Bittner , Martin Borch Jensen , Cornelis F Calkhoven , Danica Chen , Aubrey D N J de Grey , Jerome N Feige , Anastasia Georgievskaya , Vadim N Gladyshev , Tyler Golato , Andrei V Gudkov , Thorsten Hoppe , Matt Kaeberlein , Pekka Katajisto , Brian K Kennedy , Unmesh Lal , Ana Martin-Villalba , Alexey A Moskalev , Ivan Ozerov , Michael A Petr , Reason , David C Rubinsztein , Alexander Tyshkovskiy , Quentin Vanhaelen , Alex Zhavoronkov , Morten Scheibye-Knudsen

The genesis of the natural water chemistry in the South-Western Khibiny Mountains (the Malaya Belaya River Basin).

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

Avec: Svetlana I Mazukhina , Sergey S Sandimirov , Vladivir I Pozhilenko , Anton V Gudkov

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia.

Leukemia

Avec: Klaartje Somers , Kathryn Evans , Leanna Cheung , Mawar Karsa , Tara Pritchard , Angelika Kosciolek , Angelika Bongers , Ali El-Ayoubi , Helen Forgham , Shiloh Middlemiss , Chelsea Mayoh , Luke Jones , Mahima Gupta , Ursula R Kees , Olga Chernova , Lioubov Korotchkina , Andrei V Gudkov , Stephen W Erickson , Beverly Teicher , Malcolm A Smith , Murray D Norris , Michelle Haber , Richard B Lock , Michelle J Henderson

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.

Oncogene

Avec: Klaartje Somers , Victoria W Wen , Shiloh M C Middlemiss , Brenna Osborne , Helen Forgham , MoonSun Jung , Mawar Karsa , Molly Clifton , Angelika Bongers , Jixuan Gao , Chelsea Mayoh , Newsha Raoufi-Rad , Eric P Kusnadi , Kate M Hannan , David A Scott , Alan Kwek , Bing Liu , Claudia Flemming , Daria A Chudakova , Ruby Pandher , Tim W Failes , James Lim , Andrea Angeli , Andrei L Osterman , Toshihiko Imamura , Ursula R Kees , Claudiu T Supuran , Richard B Pearson , Ross D Hannan , Thomas P Davis , Joshua McCarroll , Maria Kavallaris , Nigel Turner , Andrei V Gudkov , Michelle Haber , Murray D Norris , Michelle J Henderson

Réseau de co-auteurs

Michelle Haber 6 collaborations

Murray D Norris 6 collaborations

Anatoli S Gleiberman 5 collaborations

Marina P Antoch 4 collaborations

Brandon M Hall 4 collaborations

Ekaterina L Andrianova 3 collaborations

Katerina I Leonova 3 collaborations

Chelsea Mayoh 3 collaborations

Lioubov Korotchkina 3 collaborations

Klaartje Somers 3 collaborations

Michelle J Henderson 3 collaborations

Srabani Pal 2 collaborations

Craig M Brackett 2 collaborations

Ivan Molodtsov 2 collaborations

Bojidar M Kandar 2 collaborations

Lyudmila G Burdelya 2 collaborations

Ilia Toshkov 2 collaborations

Valeria Kogan 2 collaborations

Vadim N Gladyshev 2 collaborations

Ruby Pandher 2 collaborations

Mahima Gupta 2 collaborations

Slavoljub Vujcic 2 collaborations

Shiloh Middlemiss 2 collaborations

Richard B Lock 2 collaborations

Olga B Chernova 2 collaborations

Ksenia A Novototskaya-Vlasova 2 collaborations

Olga V Leontieva 2 collaborations

Andrei L Osterman 2 collaborations

Mawar Karsa 2 collaborations

Angelika Bongers 2 collaborations

Helen Forgham 2 collaborations

Ursula R Kees 2 collaborations

Timothy V Pyrkov 1 collaboration

Konstantin Avchaciov 1 collaboration

Andrei E Tarkhov 1 collaboration

Leonid I Menshikov 1 collaboration

Peter O Fedichev 1 collaboration

Natalia V Eremina 1 collaboration

Vasily I Kazey 1 collaboration

Sergey V Mishugin 1 collaboration

Roman V Leonenkov 1 collaboration

Dmitry Y Pushkar 1 collaboration

Vadim L Mett 1 collaboration

Suvranil Ghosh 1 collaboration

Naibedya Dutta 1 collaboration

Pinaki Banerjee 1 collaboration

Rahul L Gajbhiye 1 collaboration

Hossainoor Rahaman Sareng 1 collaboration

Prachi Kapse 1 collaboration

Lyudmila Burdelya 1 collaboration

Narayan C Mandal 1 collaboration

Velyutham Ravichandiran 1 collaboration

Ashish Bhattacharjee 1 collaboration

Gopal C Kundu 1 collaboration

Mahadeb Pal 1 collaboration

Catherine A Burkhart 1 collaboration

Mikhail A Nikiforov 1 collaboration

Kellee F Greene 1 collaboration

Alyssa R Aldrich 1 collaboration

Nicholas H Trageser 1 collaboration

Scott I Abrams 1 collaboration

Michelle Wrobel 1 collaboration

Bryan Gillard 1 collaboration

Karen K Kuropatwinski 1 collaboration

Ellen Karasik 1 collaboration

Michael T Moser 1 collaboration

Barbara A Foster 1 collaboration

Olga V Chernova 1 collaboration

Matthew Simon 1 collaboration

Michael Van Meter 1 collaboration

Julia Ablaeva 1 collaboration

Zhonghe Ke 1 collaboration

Raul S Gonzalez 1 collaboration

Taketo Taguchi 1 collaboration

Marco De Cecco 1 collaboration

Stephen L Helfand 1 collaboration

Nicola Neretti 1 collaboration

Asael Roichman 1 collaboration

Haim Y Cohen 1 collaboration

Margarita V Meer 1 collaboration

John M Sedivy 1 collaboration

Andrei Seluanov 1 collaboration

Vera Gorbunova 1 collaboration

Jie-Yu Liu 1 collaboration

George P Souroullas 1 collaboration

Brian O Diekman 1 collaboration

Janakiraman Krishnamurthy 1 collaboration

Jessica A Sorrentino 1 collaboration

Joel S Parker 1 collaboration

Garrett A Sessions 1 collaboration

Norman E Sharpless 1 collaboration

Anahid Ehteda 1 collaboration

Sandy Simon 1 collaboration

Laura Franshaw 1 collaboration

Federico M Giorgi 1 collaboration

Jie Liu 1 collaboration

Swapna Joshi 1 collaboration

Jourdin R C Rouaen 1 collaboration

Chi Nam Ignatius Pang 1 collaboration

Yujie Tang 1 collaboration

Aaminah Khan 1 collaboration

Caitlin Ung 1 collaboration

Ornella Tolhurst 1 collaboration

Anne Kankean 1 collaboration

Elisha Hayden 1 collaboration

Rebecca Lehmann 1 collaboration

Sylvie Shen 1 collaboration

Anjana Gopalakrishnan 1 collaboration

Peter Trebilcock 1 collaboration

Katerina Gurova 1 collaboration

Orazio Vittorio 1 collaboration

Maria Tsoli 1 collaboration

David S Ziegler 1 collaboration

Tara A Barone 1 collaboration

Denisha L Robinson 1 collaboration

Jingxin Qiu 1 collaboration

Katerina V Gurova 1 collaboration

Andrei A Purmal 1 collaboration

Robert J Plunkett 1 collaboration

Gary J Haderski 1 collaboration

Ilia M Toshkov 1 collaboration

Christopher P Johnson 1 collaboration

Geraldine M Paszkiewicz 1 collaboration

Venkatesh Natarajan 1 collaboration

Denis Kazyulkin 1 collaboration

Pavel G Komarov 1 collaboration

Alex Polinsky 1 collaboration

Sangeeta Joshi 1 collaboration

Eugene Kononov 1 collaboration

Yuan Tian 1 collaboration

Peter Krasnov 1 collaboration

Mikhail V Chernov 1 collaboration

Jean Veith 1 collaboration

Ian Miller 1 collaboration

Max Totrov 1 collaboration

Denis N Kazyulkin 1 collaboration

Sergey Korolev 1 collaboration

Nickolay S Neznanov 1 collaboration

Mairead Commane 1 collaboration

Jayne Murray 1 collaboration

Alexandra V Vylegzhanina 1 collaboration

Ivan A Bespalov 1 collaboration

Han Yu 1 collaboration

Oleg V Kurnasov 1 collaboration

Grace K Dy 1 collaboration

Alexey A Komissarov 1 collaboration

Elena Vasilieva 1 collaboration

Jeff Gehlhausen 1 collaboration

Akiko Iwasaki 1 collaboration

Christine B Ambrosone 1 collaboration

Takemasa Tsuji 1 collaboration

Junko Matsuzaki 1 collaboration

Kunle Odunsi 1 collaboration

Evguenia Strom 1 collaboration

Peter A Krasnov 1 collaboration

David Frescas 1 collaboration

Igor E Koman 1 collaboration

Yi Zhu 1 collaboration

Tamara Tchkonia 1 collaboration

James L Kirkland 1 collaboration

Daniela Bakula 1 collaboration

Andrea Ablasser 1 collaboration

Adriano Aguzzi 1 collaboration

Adam Antebi 1 collaboration

Nir Barzilai 1 collaboration

Martin-Immanuel Bittner 1 collaboration

Martin Borch Jensen 1 collaboration

Cornelis F Calkhoven 1 collaboration

Danica Chen 1 collaboration

Aubrey D N J de Grey 1 collaboration

Jerome N Feige 1 collaboration

Anastasia Georgievskaya 1 collaboration

Tyler Golato 1 collaboration

Thorsten Hoppe 1 collaboration

Matt Kaeberlein 1 collaboration

Pekka Katajisto 1 collaboration

Brian K Kennedy 1 collaboration

Unmesh Lal 1 collaboration

Ana Martin-Villalba 1 collaboration

Alexey A Moskalev 1 collaboration

Ivan Ozerov 1 collaboration

Michael A Petr 1 collaboration

None Reason 1 collaboration

David C Rubinsztein 1 collaboration

Alexander Tyshkovskiy 1 collaboration

Quentin Vanhaelen 1 collaboration

Alex Zhavoronkov 1 collaboration

Morten Scheibye-Knudsen 1 collaboration

Svetlana I Mazukhina 1 collaboration

Sergey S Sandimirov 1 collaboration

Vladivir I Pozhilenko 1 collaboration

Anton V Gudkov 1 collaboration

Kathryn Evans 1 collaboration

Leanna Cheung 1 collaboration

Tara Pritchard 1 collaboration

Angelika Kosciolek 1 collaboration

Ali El-Ayoubi 1 collaboration

Luke Jones 1 collaboration

Olga Chernova 1 collaboration

Stephen W Erickson 1 collaboration

Beverly Teicher 1 collaboration

Malcolm A Smith 1 collaboration

Victoria W Wen 1 collaboration

Shiloh M C Middlemiss 1 collaboration

Brenna Osborne 1 collaboration

MoonSun Jung 1 collaboration

Molly Clifton 1 collaboration

Jixuan Gao 1 collaboration

Newsha Raoufi-Rad 1 collaboration

Eric P Kusnadi 1 collaboration

Kate M Hannan 1 collaboration

David A Scott 1 collaboration

Alan Kwek 1 collaboration

Bing Liu 1 collaboration

Claudia Flemming 1 collaboration

Daria A Chudakova 1 collaboration

Tim W Failes 1 collaboration

James Lim 1 collaboration

Andrea Angeli 1 collaboration

Toshihiko Imamura 1 collaboration

Claudiu T Supuran 1 collaboration

Richard B Pearson 1 collaboration

Ross D Hannan 1 collaboration

Thomas P Davis 1 collaboration

Joshua McCarroll 1 collaboration

Maria Kavallaris 1 collaboration

Nigel Turner 1 collaboration