Alexandre Wohlkönig

Affiliations

Center for Structural Biology, Vlaams Instituut voor Biotechnology (VIB), B-1050 Brussels, Belgium.

Publications (8)

A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.

Biochimica et biophysica acta. Proteins and proteomics

Avec: Abdalkarim Tanina , Alexandre Wohlkönig , Sameh H Soror , Marion Flipo , Baptiste Villemagne , Hugues Prevet , Benoit Déprez , Martin Moune , Hélène Perée , Franck Meyer , Alain R Baulard , Nicolas Willand , René Wintjens

Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.

Angewandte Chemie (International ed. in English)

Avec: Kevin Van Holsbeeck , Baptiste Fischer , Simon Gonzalez , Charlène Gadais , Wim Versées , José C Martins , Charlotte Martin , Alexandre Wohlkönig , Jan Steyaert , Steven Ballet

Allosteric nanobodies to study the interactions between SOS1 and RAS.

Nature communications

Avec: Baptiste Fischer , Tomasz Uchański , Aidana Sheryazdanova , Simon Gonzalez , Alexander N Volkov , Elke Brosens , Thomas Zögg , Valentina Kalichuk , Steven Ballet , Wim Versées , Anna A Sablina , Els Pardon , Alexandre Wohlkönig , Jan Steyaert

An improved yeast surface display platform for the screening of nanobody immune libraries.

Scientific reports

Avec: Tomasz Uchański , Thomas Zögg , Jie Yin , Daopeng Yuan , Alexandre Wohlkönig , Baptiste Fischer , Daniel M Rosenbaum , Brian K Kobilka , Els Pardon , Jan Steyaert

Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.

Nature methods

Avec: Tomasz Uchański , Simonas Masiulis , Baptiste Fischer , Valentina Kalichuk , Uriel López-Sánchez , Eleftherios Zarkadas , Miriam Weckener , Andrija Sente , Philip Ward , Alexandre Wohlkönig , Thomas Zögg , Han Remaut , James H Naismith , Hugues Nury , Wim Vranken , A Radu Aricescu , Els Pardon , Jan Steyaert

Fragment-Based Optimized EthR Inhibitors with

ACS infectious diseases

Avec: Baptiste Villemagne , Arnaud Machelart , Ngoc Chau Tran , Marion Flipo , Martin Moune , Florence Leroux , Catherine Piveteau , Alexandre Wohlkönig , René Wintjens , Xue Li , Ruxandra Gref , Priscille Brodin , Benoit Deprez , Alain R Baulard , Nicolas Willand

Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility.

FEBS letters

Avec: Dong Yang , Guy Vandenbussche , Didier Vertommen , Damien Evrard , Romany Abskharon , Jean-François Cavalier , Gilles Berger , Stéphane Canaan , Mohammad Shahneawz Khan , Sheng Zeng , Alexandre Wohlkönig , Martine Prévost , Patrice Soumillion , Véronique Fontaine

A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.

European journal of medicinal chemistry

Avec: Hugues Prevet , Martin Moune , Abdalkarim Tanina , Christian Kemmer , Adrien Herledan , Rosangela Frita , Alexandre Wohlkönig , Marilyne Bourotte , Baptiste Villemagne , Florence Leroux , Marc Gitzinger , Alain R Baulard , Benoit Déprez , René Wintjens , Nicolas Willand , Marion Flipo

Réseau de co-auteurs

Baptiste Fischer 4 collaborations

Jan Steyaert 4 collaborations

Marion Flipo 3 collaborations

Baptiste Villemagne 3 collaborations

Martin Moune 3 collaborations

Alain R Baulard 3 collaborations

Nicolas Willand 3 collaborations

René Wintjens 3 collaborations

Tomasz Uchański 3 collaborations

Thomas Zögg 3 collaborations

Els Pardon 3 collaborations

Abdalkarim Tanina 2 collaborations

Hugues Prevet 2 collaborations

Benoit Déprez 2 collaborations

Simon Gonzalez 2 collaborations

Wim Versées 2 collaborations

Steven Ballet 2 collaborations

Valentina Kalichuk 2 collaborations

Florence Leroux 2 collaborations

Sameh H Soror 1 collaboration

Hélène Perée 1 collaboration

Franck Meyer 1 collaboration

Kevin Van Holsbeeck 1 collaboration

Charlène Gadais 1 collaboration

José C Martins 1 collaboration

Charlotte Martin 1 collaboration

Aidana Sheryazdanova 1 collaboration

Alexander N Volkov 1 collaboration

Elke Brosens 1 collaboration

Anna A Sablina 1 collaboration

Jie Yin 1 collaboration

Daopeng Yuan 1 collaboration

Daniel M Rosenbaum 1 collaboration

Brian K Kobilka 1 collaboration

Simonas Masiulis 1 collaboration

Uriel López-Sánchez 1 collaboration

Eleftherios Zarkadas 1 collaboration

Miriam Weckener 1 collaboration

Andrija Sente 1 collaboration

Philip Ward 1 collaboration

Han Remaut 1 collaboration

James H Naismith 1 collaboration

Hugues Nury 1 collaboration

Wim Vranken 1 collaboration

A Radu Aricescu 1 collaboration

Arnaud Machelart 1 collaboration

Ngoc Chau Tran 1 collaboration

Catherine Piveteau 1 collaboration

Xue Li 1 collaboration

Ruxandra Gref 1 collaboration

Priscille Brodin 1 collaboration

Benoit Deprez 1 collaboration

Dong Yang 1 collaboration

Guy Vandenbussche 1 collaboration

Didier Vertommen 1 collaboration

Damien Evrard 1 collaboration

Romany Abskharon 1 collaboration

Jean-François Cavalier 1 collaboration

Gilles Berger 1 collaboration

Stéphane Canaan 1 collaboration

Mohammad Shahneawz Khan 1 collaboration

Sheng Zeng 1 collaboration

Martine Prévost 1 collaboration

Patrice Soumillion 1 collaboration

Véronique Fontaine 1 collaboration

Christian Kemmer 1 collaboration

Adrien Herledan 1 collaboration

Rosangela Frita 1 collaboration

Marilyne Bourotte 1 collaboration

Marc Gitzinger 1 collaboration