Vijayabhaskar Veeravalli

Affiliations

Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.

Publications (15)

Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker.

Bioorganic & medicinal chemistry

Avec: Bridget Duvall , Sarah C Zimmermann , Run-Duo Gao , Ajit G Thomas , Filip Kalčic , Amira Elgogary , Rana Rais , Camilo Rojas , Anne Le , Barbara S Slusher , Takashi Tsukamoto

Critical Assessment of Pharmacokinetic Drug-Drug Interaction Potential of Tofacitinib, Baricitinib and Upadacitinib, the Three Approved Janus Kinase Inhibitors for Rheumatoid Arthritis Treatment.

Drug safety

Avec: Ranjeet P Dash , Jennifer A Thomas , R Jayachandra Babu , Lakshmi Mohan Vamsi Madgula , Nuggehally R Srinivas

Discovery of

Journal of medicinal chemistry

Avec: Kateřina Novotná , Lukáš Tenora , Eva Prchalová , James Paule , Jesse Alt , Vijay Veeravalli , Jenny Lam , Ying Wu , Ivan Šnajdr , Sadakatali Gori , Vijaya Saradhi Mettu , Takashi Tsukamoto , Pavel Majer , Barbara S Slusher , Rana Rais

A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis.

Science translational medicine

Avec: Diane E Peters , Lauren D Norris , Lukáš Tenora , Ivan Šnajdr , András K Ponti , Xiaolei Zhu , Shinji Sakamoto , Manisha Pradhan , Jesse Alt , Ajit G Thomas , Pavel Majer , Rana Rais , Christine McDonald , Barbara S Slusher

Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's Disease.

Journal of medicinal chemistry

Avec: Michal Šála , Kristen R Hollinger , Ajit G Thomas , Ranjeet P Dash , Carolyn Tallon , Lyndah Lovell , Martin Kögler , Hubert Hřebabecký , Eliška Procházková , Ondřej Nešuta , Amanda Donoghue , Jenny Lam , Rana Rais , Camilo Rojas , Barbara S Slusher , Radim Nencka

Enhanced Oral Bioavailability of 2-(Phosphonomethyl)-pentanedioic Acid (2-PMPA) from its (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (ODOL)-Based Prodrugs.

Molecular pharmaceutics

Avec: Ranjeet P Dash , Tomáš Tichý , Jenny Lam , Jesse Alt , Ying Wu , Lukáš Tenora , Pavel Majer , Barbara S Slusher , Rana Rais

Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter.

Molecular psychiatry

Avec: Maged M Harraz , Prasun Guha , In Guk Kang , Evan R Semenza , Adarsha P Malla , Young Jun Song , Luke Reilly , Isaac Treisman , Pedro Cortés , Mark A Coggiano , Rana Rais , Gianluigi Tanda , Solomon H Snyder

Application of Mechanistic Multiparameter Optimization and Large-Scale

Molecular pharmaceutics

Avec: Fabio Broccatelli , Daniel Cashion , Javier L Baylon , Franco Lombardo , Lei Jia

The Novel Glutamine Antagonist Prodrug JHU395 Has Antitumor Activity in Malignant Peripheral Nerve Sheath Tumor.

Molecular cancer therapeutics

Avec: Kathryn M Lemberg , Liang Zhao , Ying Wu , Jesse Alt , Joanna Marie H Aguilar , Ranjeet P Dash , Jenny Lam , Lukáš Tenora , Chabely Rodriguez , Michael T Nedelcovych , Cory Brayton , Pavel Majer , Jaishri O Blakeley , Rana Rais , Barbara S Slusher

Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists.

Journal of medicinal chemistry

Avec: Eva Prchalová , Niyada Hin , Ajit G Thomas , Justin Ng , Jesse Alt , Rana Rais , Camilo Rojas , Zhe Li , Hiroe Hihara , Mika Aoki , Kyoko Yoshizawa , Tomoki Nishioka , Shuichi Suzuki , Theresa Kopajtic , Sheena Chatrath , Qin Liu , Xinzhong Dong , Barbara S Slusher , Takashi Tsukamoto

Tumor-Targeted Delivery of 6-Diazo-5-oxo-l-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs.

Journal of medicinal chemistry

Avec: Lukáš Tenora , Jesse Alt , Ranjeet P Dash , Alexandra J Gadiano , Kateřina Novotná , Jenny Lam , Quinn R Kirkpatrick , Kathryn M Lemberg , Pavel Majer , Rana Rais , Barbara S Slusher

Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target Engagement.

Current drug metabolism

Avec: Jesse Alt , Sadakatali S Gori , Kathryn M Lemberg , Arindom Pal , Ying Wu , Joanna M H Aguilar , Ranjeet P Dash , Lukáš Tenora , Pavel Majer , Qi Sun , Barbara S Slusher , Rana Rais

Three-dimensional aspects of formulation excipients in drug discovery: a critical assessment on orphan excipients, matrix effects and drug interactions.

Journal of pharmaceutical analysis

Avec: Hanumanth Srikanth Cheruvu , Pratima Srivastava , Lakshmi Mohan Vamsi Madgula

Whole blood or plasma: what is the ideal matrix for pharmacokinetic-driven drug candidate selection?

Future medicinal chemistry

Avec: Ranjeet P Dash , Jennifer A Thomas , Clint Rosenfeld , Nirali Mehta , Nuggehally R Srinivas

Thieno[2,3-

Journal of medicinal chemistry

Avec: Ilyas Berhane , Niyada Hin , Ajit G Thomas , Qian Huang , Chi Zhang , Ying Wu , Justin Ng , Jesse Alt , Camilo Rojas , Hiroe Hihara , Mika Aoki , Kyoko Yoshizawa , Tomoki Nishioka , Shuichi Suzuki , Shao-Qiu He , Qi Peng , Yun Guan , Xinzhong Dong , Srinivasa N Raja , Barbara S Slusher , Rana Rais , Takashi Tsukamoto

Réseau de co-auteurs

Rana Rais 11 collaborations

Barbara S Slusher 10 collaborations

Jesse Alt 8 collaborations

Ranjeet P Dash 7 collaborations

Lukáš Tenora 6 collaborations

Pavel Majer 6 collaborations

Ajit G Thomas 5 collaborations

Jenny Lam 5 collaborations

Ying Wu 5 collaborations

Camilo Rojas 4 collaborations

Takashi Tsukamoto 4 collaborations

Kathryn M Lemberg 3 collaborations

Jennifer A Thomas 2 collaborations

Lakshmi Mohan Vamsi Madgula 2 collaborations

Nuggehally R Srinivas 2 collaborations

Kateřina Novotná 2 collaborations

Eva Prchalová 2 collaborations

Ivan Šnajdr 2 collaborations

Niyada Hin 2 collaborations

Justin Ng 2 collaborations

Hiroe Hihara 2 collaborations

Mika Aoki 2 collaborations

Kyoko Yoshizawa 2 collaborations

Tomoki Nishioka 2 collaborations

Shuichi Suzuki 2 collaborations

Xinzhong Dong 2 collaborations

Bridget Duvall 1 collaboration

Sarah C Zimmermann 1 collaboration

Run-Duo Gao 1 collaboration

Filip Kalčic 1 collaboration

Amira Elgogary 1 collaboration

Anne Le 1 collaboration

R Jayachandra Babu 1 collaboration

James Paule 1 collaboration

Vijay Veeravalli 1 collaboration

Sadakatali Gori 1 collaboration

Vijaya Saradhi Mettu 1 collaboration

Diane E Peters 1 collaboration

Lauren D Norris 1 collaboration

András K Ponti 1 collaboration

Xiaolei Zhu 1 collaboration

Shinji Sakamoto 1 collaboration

Manisha Pradhan 1 collaboration

Christine McDonald 1 collaboration

Michal Šála 1 collaboration

Kristen R Hollinger 1 collaboration

Carolyn Tallon 1 collaboration

Lyndah Lovell 1 collaboration

Martin Kögler 1 collaboration

Hubert Hřebabecký 1 collaboration

Eliška Procházková 1 collaboration

Ondřej Nešuta 1 collaboration

Amanda Donoghue 1 collaboration

Radim Nencka 1 collaboration

Tomáš Tichý 1 collaboration

Maged M Harraz 1 collaboration

Prasun Guha 1 collaboration

In Guk Kang 1 collaboration

Evan R Semenza 1 collaboration

Adarsha P Malla 1 collaboration

Young Jun Song 1 collaboration

Luke Reilly 1 collaboration

Isaac Treisman 1 collaboration

Pedro Cortés 1 collaboration

Mark A Coggiano 1 collaboration

Gianluigi Tanda 1 collaboration

Solomon H Snyder 1 collaboration

Fabio Broccatelli 1 collaboration

Daniel Cashion 1 collaboration

Javier L Baylon 1 collaboration

Franco Lombardo 1 collaboration

Lei Jia 1 collaboration

Liang Zhao 1 collaboration

Joanna Marie H Aguilar 1 collaboration

Chabely Rodriguez 1 collaboration

Michael T Nedelcovych 1 collaboration

Cory Brayton 1 collaboration

Jaishri O Blakeley 1 collaboration

Zhe Li 1 collaboration

Theresa Kopajtic 1 collaboration

Sheena Chatrath 1 collaboration

Qin Liu 1 collaboration

Alexandra J Gadiano 1 collaboration

Quinn R Kirkpatrick 1 collaboration

Sadakatali S Gori 1 collaboration

Arindom Pal 1 collaboration

Joanna M H Aguilar 1 collaboration

Qi Sun 1 collaboration

Hanumanth Srikanth Cheruvu 1 collaboration

Pratima Srivastava 1 collaboration

Clint Rosenfeld 1 collaboration

Nirali Mehta 1 collaboration

Ilyas Berhane 1 collaboration

Qian Huang 1 collaboration

Chi Zhang 1 collaboration

Shao-Qiu He 1 collaboration

Qi Peng 1 collaboration

Yun Guan 1 collaboration

Srinivasa N Raja 1 collaboration