Sebastien A Burel

Affiliations

Preclinical Development, Ionis Pharmaceuticals, Carlsbad, California.

Publications (6)

Hybrid Mouse Diversity Panel Identifies Genetic Architecture Associated with the Acute Antisense Oligonucleotide-Mediated Inflammatory Response to a 2'-

Nucleic acid therapeutics

Avec: Elaine Pirie , Patrick Cauntay , Wuxia Fu , Shayoni Ray , Calvin Pan , Aldonis J Lusis , Jill Hsiao , Padma Narayanan , Rosanne M Crooke , Richard G Lee

Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.

Nucleic acid therapeutics

Avec: PadmaKumar Narayanan , Brian R Curtis , Lijiang Shen , Eugene Schneider , Joseph A Tami , Suzanne Paz , Li-Jung Tai , Todd Machemer , T Jesse Kwoh , Shuting Xia , Sanford J Shattil , Joseph L Witztum , Jeffery A Engelhardt , Scott P Henry , Brett P Monia , Steven G Hughes

Comparison of the Class Effects of Antisense Oligonucleotides in CByB6F1-Tg(HRAS)2Jic and CD-1 Mice.

Toxicologic pathology

Avec: Tae-Won Kim , Chris N Papagiannis , Laura S Zwick , Jeffery A Engelhardt , Christine M Hoffmaster , Noah M Post , John E Matson , Jill A Hsiao , Scott P Henry

Early-Stage Identification and Avoidance of Antisense Oligonucleotides Causing Species-Specific Inflammatory Responses in Human Volunteer Peripheral Blood Mononuclear Cells.

Nucleic acid therapeutics

Avec: Todd Machemer , Brenda F Baker , T Jesse Kwoh , Suzanne Paz , Husam Younis , Scott P Henry

Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides.

Nucleic acids research

Avec: Brooke A Anderson , Graeme C Freestone , Audrey Low , Cheryl L De-Hoyos , William J Drury Iii , Michael E Østergaard , Michael T Migawa , Michael Fazio , W Brad Wan , Andres Berdeja , Eli Scandalis , Timothy A Vickers , Stanley T Crooke , Eric E Swayze , Xuehai Liang , Punit P Seth

Correlations between preclinical BJAB assay ranking of antisense drugs and clinical trial adverse events.

Clinical and translational science

Avec: Wesley Partridge , Annie Ferng , Shuting Xia , T Jesse Kwoh , Scott P Henry , Brenda F Baker

Réseau de co-auteurs

Scott P Henry 4 collaborations

T Jesse Kwoh 3 collaborations

Suzanne Paz 2 collaborations

Todd Machemer 2 collaborations

Shuting Xia 2 collaborations

Jeffery A Engelhardt 2 collaborations

Brenda F Baker 2 collaborations

Elaine Pirie 1 collaboration

Patrick Cauntay 1 collaboration

Wuxia Fu 1 collaboration

Shayoni Ray 1 collaboration

Calvin Pan 1 collaboration

Aldonis J Lusis 1 collaboration

Jill Hsiao 1 collaboration

Padma Narayanan 1 collaboration

Rosanne M Crooke 1 collaboration

Richard G Lee 1 collaboration

PadmaKumar Narayanan 1 collaboration

Brian R Curtis 1 collaboration

Lijiang Shen 1 collaboration

Eugene Schneider 1 collaboration

Joseph A Tami 1 collaboration

Li-Jung Tai 1 collaboration

Sanford J Shattil 1 collaboration

Joseph L Witztum 1 collaboration

Brett P Monia 1 collaboration

Steven G Hughes 1 collaboration

Tae-Won Kim 1 collaboration

Chris N Papagiannis 1 collaboration

Laura S Zwick 1 collaboration

Christine M Hoffmaster 1 collaboration

Noah M Post 1 collaboration

John E Matson 1 collaboration

Jill A Hsiao 1 collaboration

Husam Younis 1 collaboration

Brooke A Anderson 1 collaboration

Graeme C Freestone 1 collaboration

Audrey Low 1 collaboration

Cheryl L De-Hoyos 1 collaboration

William J Drury Iii 1 collaboration

Michael E Østergaard 1 collaboration

Michael T Migawa 1 collaboration

Michael Fazio 1 collaboration

W Brad Wan 1 collaboration

Andres Berdeja 1 collaboration

Eli Scandalis 1 collaboration

Timothy A Vickers 1 collaboration

Stanley T Crooke 1 collaboration

Eric E Swayze 1 collaboration

Xuehai Liang 1 collaboration

Punit P Seth 1 collaboration

Wesley Partridge 1 collaboration

Annie Ferng 1 collaboration