Pietro Delre

Affiliations

Chemistry Department, University of Bari "Aldo Moro", via E. Orabona, 4, I-70125 Bari, Italy.
CNR─Institute of Crystallography, Via Amendola 122/o, 70126 Bari, Italy.

Publications (25)

DeLA-Drug: A Deep Learning Algorithm for Automated Design of Druglike Analogues.

Journal of chemical information and modeling

Avec: Teresa Maria Creanza , Giuseppe Lamanna , Marialessandra Contino , Nicola Corriero , Michele Saviano , Giuseppe Felice Mangiatordi , Nicola Ancona

Development of Fluorescent 4-[4-(3

Journal of medicinal chemistry

Avec: Francesca Serena Abatematteo , Maria Majellaro , Bianca Montsch , Rubén Prieto-Díaz , Mauro Niso , Marialessandra Contino , Angela Stefanachi , Chiara Riganti , Giuseppe Felice Mangiatordi , Petra Heffeter , Eddy Sotelo , Carmen Abate

Endocannabinoid Degradation Enzyme Inhibitors as Potential Antipsychotics: A Medicinal Chemistry Perspective.

Biomedicines

Avec: Giuseppe Felice Mangiatordi , Maria Maddalena Cavalluzzi , Giuseppe Lamanna , Maria Cristina Lumuscio , Michele Saviano , Jean-Pierre Majoral , Serge Mignani , Andrea Duranti , Giovanni Lentini

A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach.

Scientific reports

Avec: Francesca Serena Abatematteo , Ivan Mercurio , Veronica V Rezelj , Dritan Siliqi , Stephanie Beaucourt , Gianluca Lattanzi , Nicola Antonio Colabufo , Marcello Leopoldo , Michele Saviano , Marco Vignuzzi , Giuseppe Felice Mangiatordi , Carmen Abate

Structure-Based Prediction of hERG-Related Cardiotoxicity: A Benchmark Study.

Journal of chemical information and modeling

Avec: Teresa Maria Creanza , Nicola Ancona , Giovanni Lentini , Michele Saviano , Giuseppe Felice Mangiatordi

ALPACA: A machine Learning Platform for Affinity and selectivity profiling of CAnnabinoids receptors modulators.

Computers in biology and medicine

Avec: Marialessandra Contino , Domenico Alberga , Michele Saviano , Nicola Corriero , Giuseppe Felice Mangiatordi

N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R).

European journal of medicinal chemistry

Avec: Giovanni Graziano , Francesca Carofiglio , Josè Brea , Alessia Ligresti , Magdalena Kostrzewa , Chiara Riganti , Claudia Gioè-Gallo , Maria Majellaro , Orazio Nicolotti , Nicola Antonio Colabufo , Carmen Abate , Maria Isabel Loza , Eddy Sotelo , Giuseppe Felice Mangiatordi , Marialessandra Contino , Angela Stefanachi , Francesco Leonetti

Targeting Siderophore-Mediated Iron Uptake in

Pharmaceutics

Avec: Matteo Mori , Giovanni Stelitano , Giulia Cazzaniga , Arianna Gelain , Andrea Tresoldi , Mario Cocorullo , Martina Roversi , Laurent R Chiarelli , Martina Tomaiuolo , Giuseppe F Mangiatordi , Anna Griego , Loris Rizzello , Alberto Cassetta , Sonia Covaceuszach , Stefania Villa , Fiorella Meneghetti

Journal of medicinal chemistry

Avec: Francesca Intranuovo , Maria Majellaro , Francesco Mastropasqua , Francesca Serena Abatematteo , Giuseppe Felice Mangiatordi , Angela Stefanachi , Josè Brea , Maria Isabel Loza , Chiara Riganti , Alessia Ligresti , Poulami Kumar , Daniela Esposito , Luigia Cristino , Alessandro Nicois , Lucía González , Maria Grazia Perrone , Nicola Antonio Colabufo , Eddy Sotelo , Carmen Abate , Marialessandra Contino

Radiosynthesis and characterization of [

European journal of nuclear medicine and molecular imaging

Avec: Sang Hee Lee , Nunzio Denora , Valentino Laquintana , Giuseppe Felice Mangiatordi , Angela Lopedota , Antonio Lopalco , Annalisa Cutrignelli , Massimo Franco , In Ho Song , Hye Won Kim , Su Bin Kim , Hyun Soo Park , Kyungmin Kim , Seok-Yong Lee , Hyewon Youn , Byung Chul Lee , Sang Eun Kim

Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration.

Journal of medicinal chemistry

Avec: Giuseppe Felice Mangiatordi , Francesca Intranuovo , Francesca Serena Abatematteo , Carmen Abate , Mauro Niso , Teresa Maria Creanza , Nicola Ancona , Angela Stefanachi , Marialessandra Contino

Repurposing Known Drugs as Covalent and Non-covalent Inhibitors of the SARS-CoV-2 Papain-Like Protease.

Frontiers in chemistry

Avec: Fabiana Caporuscio , Michele Saviano , Giuseppe Felice Mangiatordi

AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis.

Molecular pharmaceutics

Avec: Maria Cristina Lomuscio , Carmen Abate , Domenico Alberga , Antonio Laghezza , Nicola Corriero , Nicola Antonio Colabufo , Michele Saviano , Giuseppe Felice Mangiatordi

hERG stereoselective modulation by mexiletine-derived ureas: Molecular docking study, synthesis, and biological evaluation.

Archiv der Pharmazie

Avec: Gualtiero Milani , Roberta Budriesi , Elisa Tavazzani , Maria Maddalena Cavalluzzi , Laura Beatrice Mattioli , Daniela Valeria Miniero , Benny Danilo Belviso , Marco Denegri , Corrado Cuocci , Natalie Paola Rotondo , Annalisa De Palma , Roberta Gualdani , Rocco Caliandro , Giuseppe Felice Mangiatordi , Amit Kumawat , Carlo Camilloni , Silvia Priori , Giovanni Lentini

Exploring the role of elongation Factor-Like 1 (EFL1) in Shwachman-Diamond syndrome through molecular dynamics.

Journal of biomolecular structure & dynamics

Avec: Domenico Alberga , Abril Gijsbers , Nuria Sánchez-Puig , Orazio Nicolotti , Michele Saviano , Dritan Siliqi , Giuseppe Felice Mangiatordi

More Is Always Better Than One: The N-Terminal Domain of the Spike Protein as Another Emerging Target for Hampering the SARS-CoV-2 Attachment to Host Cells.

International journal of molecular sciences

Avec: Sonia Di Gaetano , Domenica Capasso , Luciano Pirone , Michele Saviano , Emilia Pedone , Giuseppe Felice Mangiatordi

A Comparative Molecular Dynamics Study of Selected Point Mutations in the Shwachman-Bodian-Diamond Syndrome Protein SBDS.

International journal of molecular sciences

Avec: Elena Spinetti , Michele Saviano , Dritan Siliqi , Gianluca Lattanzi , Giuseppe Felice Mangiatordi

DypB peroxidase for aflatoxin removal: New insights into the toxin degradation process.

Chemosphere

Avec: V Mangini , E Rosini , R Caliandro , G F Mangiatordi , P Delre , A G Sciancalepore , L Pollegioni , M Haidukowski , M Mazzorana , M W Sumarah , J B Renaud , R Flaig , G Mulè , B D Belviso , M Loi

Structural basis for specific inhibition of salicylate synthase from Mycobacterium abscessus.

European journal of medicinal chemistry

Avec: Matteo Mori , Mario Cocorullo , Andrea Tresoldi , Giulia Cazzaniga , Arianna Gelain , Giovanni Stelitano , Laurent R Chiarelli , Martina Tomaiuolo , Giuseppe F Mangiatordi , Mariangela Garofalo , Alberto Cassetta , Sonia Covaceuszach , Stefania Villa , Fiorella Meneghetti

Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors.

European journal of medicinal chemistry

Avec: Mariagrazia Rullo , Gabriella La Spada , Daniela Valeria Miniero , Andrea Gottinger , Marco Catto , Margherita Mastromarino , Tiziana Latronico , Sara Marchese , Giuseppe Felice Mangiatordi , Claudia Binda , Anna Linusson , Grazia Maria Liuzzi , Leonardo Pisani

Ligand-based prediction of hERG-mediated cardiotoxicity based on the integration of different machine learning techniques.

Frontiers in pharmacology

Avec: Giovanna J Lavado , Giuseppe Lamanna , Michele Saviano , Alessandra Roncaglioni , Emilio Benfenati , Giuseppe Felice Mangiatordi , Domenico Gadaleta

GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design.

Journal of chemical information and modeling

Avec: Giuseppe Lamanna , Gilles Marcou , Michele Saviano , Alexandre Varnek , Dragos Horvath , Giuseppe Felice Mangiatordi

Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels.

ACS medicinal chemistry letters

Avec: Alessandro Farinato , Maria Maddalena Cavalluzzi , Concetta Altamura , Carmen Campanale , Paola Laghetti , Ilaria Saltarella , Arthur Barbault , Nancy Tarantino , Gualtiero Milani , Natalie Paola Rotondo , Lorenzo Di Cesare Mannelli , Carla Ghelardini , Sabata Pierno , Giuseppe Felice Mangiatordi , Giovanni Lentini , Jean-François Desaphy

Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization.

European journal of medicinal chemistry

Avec: Gabriella La Spada , Daniela Valeria Miniero , Mariagrazia Rullo , Marco Cipolloni , Carolina Colliva , Marco Colella , Francesco Leonetti , Grazia Maria Liuzzi , Giuseppe Felice Mangiatordi , Nicola Giacchè , Leonardo Pisani

DeLA-DrugSelf: Empowering multi-objective de novo design through SELFIES molecular representation.

Computers in biology and medicine

Avec: Domenico Alberga , Giuseppe Lamanna , Giovanni Graziano , Maria Cristina Lomuscio , Nicola Corriero , Alessia Ligresti , Dritan Siliqi , Michele Saviano , Marialessandra Contino , Angela Stefanachi , Giuseppe Felice Mangiatordi

Réseau de co-auteurs

Giuseppe Felice Mangiatordi 22 collaborations

Michele Saviano 13 collaborations

Marialessandra Contino 7 collaborations

Carmen Abate 6 collaborations

Giuseppe Lamanna 5 collaborations

Angela Stefanachi 5 collaborations

Nicola Corriero 4 collaborations

Francesca Serena Abatematteo 4 collaborations

Giovanni Lentini 4 collaborations

Dritan Siliqi 4 collaborations

Nicola Antonio Colabufo 4 collaborations

Domenico Alberga 4 collaborations

Teresa Maria Creanza 3 collaborations

Nicola Ancona 3 collaborations

Maria Majellaro 3 collaborations

Chiara Riganti 3 collaborations

Eddy Sotelo 3 collaborations

Maria Maddalena Cavalluzzi 3 collaborations

Alessia Ligresti 3 collaborations

Daniela Valeria Miniero 3 collaborations

Mauro Niso 2 collaborations

Gianluca Lattanzi 2 collaborations

Giovanni Graziano 2 collaborations

Josè Brea 2 collaborations

Orazio Nicolotti 2 collaborations

Maria Isabel Loza 2 collaborations

Francesco Leonetti 2 collaborations

Matteo Mori 2 collaborations

Giovanni Stelitano 2 collaborations

Giulia Cazzaniga 2 collaborations

Arianna Gelain 2 collaborations

Andrea Tresoldi 2 collaborations

Mario Cocorullo 2 collaborations

Laurent R Chiarelli 2 collaborations

Martina Tomaiuolo 2 collaborations

Giuseppe F Mangiatordi 2 collaborations

Alberto Cassetta 2 collaborations

Sonia Covaceuszach 2 collaborations

Stefania Villa 2 collaborations

Fiorella Meneghetti 2 collaborations

Francesca Intranuovo 2 collaborations

Maria Cristina Lomuscio 2 collaborations

Gualtiero Milani 2 collaborations

Natalie Paola Rotondo 2 collaborations

Mariagrazia Rullo 2 collaborations

Gabriella La Spada 2 collaborations

Grazia Maria Liuzzi 2 collaborations

Leonardo Pisani 2 collaborations

Bianca Montsch 1 collaboration

Rubén Prieto-Díaz 1 collaboration

Petra Heffeter 1 collaboration

Maria Cristina Lumuscio 1 collaboration

Jean-Pierre Majoral 1 collaboration

Serge Mignani 1 collaboration

Andrea Duranti 1 collaboration

Ivan Mercurio 1 collaboration

Veronica V Rezelj 1 collaboration

Stephanie Beaucourt 1 collaboration

Marcello Leopoldo 1 collaboration

Marco Vignuzzi 1 collaboration

Francesca Carofiglio 1 collaboration

Magdalena Kostrzewa 1 collaboration

Claudia Gioè-Gallo 1 collaboration

Martina Roversi 1 collaboration

Anna Griego 1 collaboration

Loris Rizzello 1 collaboration

Francesco Mastropasqua 1 collaboration

Poulami Kumar 1 collaboration

Daniela Esposito 1 collaboration

Luigia Cristino 1 collaboration

Alessandro Nicois 1 collaboration

Lucía González 1 collaboration

Maria Grazia Perrone 1 collaboration

Sang Hee Lee 1 collaboration

Nunzio Denora 1 collaboration

Valentino Laquintana 1 collaboration

Angela Lopedota 1 collaboration

Antonio Lopalco 1 collaboration

Annalisa Cutrignelli 1 collaboration

Massimo Franco 1 collaboration

In Ho Song 1 collaboration

Hye Won Kim 1 collaboration

Su Bin Kim 1 collaboration

Hyun Soo Park 1 collaboration

Kyungmin Kim 1 collaboration

Seok-Yong Lee 1 collaboration

Hyewon Youn 1 collaboration

Byung Chul Lee 1 collaboration

Sang Eun Kim 1 collaboration

Fabiana Caporuscio 1 collaboration

Antonio Laghezza 1 collaboration

Roberta Budriesi 1 collaboration

Elisa Tavazzani 1 collaboration

Laura Beatrice Mattioli 1 collaboration

Benny Danilo Belviso 1 collaboration

Marco Denegri 1 collaboration

Corrado Cuocci 1 collaboration

Annalisa De Palma 1 collaboration

Roberta Gualdani 1 collaboration

Rocco Caliandro 1 collaboration

Amit Kumawat 1 collaboration

Carlo Camilloni 1 collaboration

Silvia Priori 1 collaboration

Abril Gijsbers 1 collaboration

Nuria Sánchez-Puig 1 collaboration

Sonia Di Gaetano 1 collaboration

Domenica Capasso 1 collaboration

Luciano Pirone 1 collaboration

Emilia Pedone 1 collaboration

Elena Spinetti 1 collaboration

V Mangini 1 collaboration

E Rosini 1 collaboration

R Caliandro 1 collaboration

G F Mangiatordi 1 collaboration

P Delre 1 collaboration

A G Sciancalepore 1 collaboration

L Pollegioni 1 collaboration

M Haidukowski 1 collaboration

M Mazzorana 1 collaboration

M W Sumarah 1 collaboration

J B Renaud 1 collaboration

R Flaig 1 collaboration

G Mulè 1 collaboration

B D Belviso 1 collaboration

M Loi 1 collaboration

Mariangela Garofalo 1 collaboration

Andrea Gottinger 1 collaboration

Marco Catto 1 collaboration

Margherita Mastromarino 1 collaboration

Tiziana Latronico 1 collaboration

Sara Marchese 1 collaboration

Claudia Binda 1 collaboration

Anna Linusson 1 collaboration

Giovanna J Lavado 1 collaboration

Alessandra Roncaglioni 1 collaboration

Emilio Benfenati 1 collaboration

Domenico Gadaleta 1 collaboration

Gilles Marcou 1 collaboration

Alexandre Varnek 1 collaboration

Dragos Horvath 1 collaboration

Alessandro Farinato 1 collaboration

Concetta Altamura 1 collaboration

Carmen Campanale 1 collaboration

Paola Laghetti 1 collaboration

Ilaria Saltarella 1 collaboration

Arthur Barbault 1 collaboration

Nancy Tarantino 1 collaboration

Lorenzo Di Cesare Mannelli 1 collaboration

Carla Ghelardini 1 collaboration

Sabata Pierno 1 collaboration

Jean-François Desaphy 1 collaboration

Marco Cipolloni 1 collaboration

Carolina Colliva 1 collaboration

Marco Colella 1 collaboration

Nicola Giacchè 1 collaboration