Pierre Broqua

Affiliations

Inventiva, 50 rue de Dijon, 21121, Daix, France.

Publications (9)

CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas.

Nature communications

Avec: Leticia Laura Niborski , Paul Gueguen , Mengliang Ye , Allan Thiolat , Rodrigo Nalio Ramos , Pamela Caudana , Jordan Denizeau , Ludovic Colombeau , Raphaël Rodriguez , Christel Goudot , Jean-Michel Luccarini , Anne Soudé , Bruno Bournique , Luigia Pace , Sylvain Baulande , Christine Sedlik , Jean-Pierre Quivy , Geneviève Almouzni , José L Cohen , Elina Zueva , Joshua J Waterfall , Sebastian Amigorena , Eliane Piaggio

Pan-PPAR agonist lanifibranor improves portal hypertension and hepatic fibrosis in experimental advanced chronic liver disease.

Journal of hepatology

Avec: Zoe Boyer-Diaz , Peio Aristu-Zabalza , María Andrés-Rozas , Claude Robert , Martí Ortega-Ribera , Anabel Fernández-Iglesias , Jean-Louis Junien , Guillaume Wettstein , Jaime Bosch , Jordi Gracia-Sancho

Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists.

Bioorganic & medicinal chemistry letters

Avec: Jérôme Amaudrut , Maria A Argiriadi , Martine Barth , Eric C Breinlinger , Didier Bressac , David J Calderwood , Mohamed Chatar , Kevin P Cusack , Stephen B Gauld , Sébastien Jacquet , Rajesh V Kamath , Michael E Kort , Valérie Lepais , Jean-Michel Luccarini , Philippe Masson , Christian Montalbetti , Laurent Mounier , Dominique Potin , Olivia Poupardin , Sylvie Rouaud , Luc Spitzer , Craig D Wallace

The pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis.

Nature communications

Avec: Michael P Cooreman , Javed Butler , Robert P Giugliano , Faiez Zannad , Lucile Dzen , Philippe Huot-Marchand , Martine Baudin , Daniel R Beard , Jean-Louis Junien , Manal F Abdelmalek , Sven M Francque

Reduction of lysosome abundance and GAG accumulation after odiparcil treatment in MPS I and MPS VI models.

Molecular genetics and metabolism reports

Avec: Pascale Tuyaa-Boustugue , Ingrid Jantzen , Haoyue Zhang , Sarah P Young , Mireille Tallandier , Eugeni Entchev

Odiparcil, a potential glycosaminoglycans clearance therapy in mucopolysaccharidosis VI-Evidence from in vitro and in vivo models.

PloS one

Avec: Eugeni Entchev , Ingrid Jantzen , Philippe Masson , Stephanie Bocart , Bruno Bournique , Jean-Michel Luccarini , Andre Bouchot , Olivier Lacombe , Jean-Louis Junien , Mireille Tallandier

A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH.

The New England journal of medicine

Avec: Sven M Francque , Pierre Bedossa , Vlad Ratziu , Quentin M Anstee , Elisabetta Bugianesi , Arun J Sanyal , Rohit Loomba , Stephen A Harrison , Rozalina Balabanska , Lyudmila Mateva , Nicolas Lanthier , Naim Alkhouri , Christophe Moreno , Jörn M Schattenberg , Diana Stefanova-Petrova , Luisa Vonghia , Régine Rouzier , Maeva Guillaume , Alexander Hodge , Manuel Romero-Gómez , Philippe Huot-Marchand , Martine Baudin , Marie-Paule Richard , Jean-Louis Abitbol , Jean-Louis Junien , Manal F Abdelmalek , Auteur inconnu

The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis.

Arthritis research & therapy

Avec: Emma Derrett-Smith , Kristina E N Clark , Xu Shiwen , David J Abraham , Rachel K Hoyles , Olivier Lacombe , Jean Louis Junien , Irena Konstantinova , Voon H Ong , Christopher P Denton

Biomarkers of Glycosaminoglycans (GAG) accumulation in patients with mucopolysaccharidosis type VI-LeukoGAG, Corneal Opacification (COM) and Carotid Intima Media Thickening (CIMT).

Molecular genetics and metabolism reports

Avec: Young Bae Sohn , Raymond Wang , Jane Ashworth , Mireille Tallandier , Jean-Louis Abitbol , Erin Jozwiak , Laura Pollard , Timothy C Wood , Tariq Aslam , Paul R Harmatz

Réseau de co-auteurs

Jean-Louis Junien 4 collaborations

Jean-Michel Luccarini 3 collaborations

Mireille Tallandier 3 collaborations

Bruno Bournique 2 collaborations

Philippe Masson 2 collaborations

Philippe Huot-Marchand 2 collaborations

Martine Baudin 2 collaborations

Manal F Abdelmalek 2 collaborations

Sven M Francque 2 collaborations

Ingrid Jantzen 2 collaborations

Eugeni Entchev 2 collaborations

Olivier Lacombe 2 collaborations

Jean-Louis Abitbol 2 collaborations

Leticia Laura Niborski 1 collaboration

Paul Gueguen 1 collaboration

Mengliang Ye 1 collaboration

Allan Thiolat 1 collaboration

Rodrigo Nalio Ramos 1 collaboration

Pamela Caudana 1 collaboration

Jordan Denizeau 1 collaboration

Ludovic Colombeau 1 collaboration

Raphaël Rodriguez 1 collaboration

Christel Goudot 1 collaboration

Anne Soudé 1 collaboration

Luigia Pace 1 collaboration

Sylvain Baulande 1 collaboration

Christine Sedlik 1 collaboration

Jean-Pierre Quivy 1 collaboration

Geneviève Almouzni 1 collaboration

José L Cohen 1 collaboration

Elina Zueva 1 collaboration

Joshua J Waterfall 1 collaboration

Sebastian Amigorena 1 collaboration

Eliane Piaggio 1 collaboration

Zoe Boyer-Diaz 1 collaboration

Peio Aristu-Zabalza 1 collaboration

María Andrés-Rozas 1 collaboration

Claude Robert 1 collaboration

Martí Ortega-Ribera 1 collaboration

Anabel Fernández-Iglesias 1 collaboration

Guillaume Wettstein 1 collaboration

Jaime Bosch 1 collaboration

Jordi Gracia-Sancho 1 collaboration

Jérôme Amaudrut 1 collaboration

Maria A Argiriadi 1 collaboration

Martine Barth 1 collaboration

Eric C Breinlinger 1 collaboration

Didier Bressac 1 collaboration

David J Calderwood 1 collaboration

Mohamed Chatar 1 collaboration

Kevin P Cusack 1 collaboration

Stephen B Gauld 1 collaboration

Sébastien Jacquet 1 collaboration

Rajesh V Kamath 1 collaboration

Michael E Kort 1 collaboration

Valérie Lepais 1 collaboration

Christian Montalbetti 1 collaboration

Laurent Mounier 1 collaboration

Dominique Potin 1 collaboration

Olivia Poupardin 1 collaboration

Sylvie Rouaud 1 collaboration

Luc Spitzer 1 collaboration

Craig D Wallace 1 collaboration

Michael P Cooreman 1 collaboration

Javed Butler 1 collaboration

Robert P Giugliano 1 collaboration

Faiez Zannad 1 collaboration

Lucile Dzen 1 collaboration

Daniel R Beard 1 collaboration

Pascale Tuyaa-Boustugue 1 collaboration

Haoyue Zhang 1 collaboration

Sarah P Young 1 collaboration

Stephanie Bocart 1 collaboration

Andre Bouchot 1 collaboration

Pierre Bedossa 1 collaboration

Vlad Ratziu 1 collaboration

Quentin M Anstee 1 collaboration

Elisabetta Bugianesi 1 collaboration

Arun J Sanyal 1 collaboration

Rohit Loomba 1 collaboration

Stephen A Harrison 1 collaboration

Rozalina Balabanska 1 collaboration

Lyudmila Mateva 1 collaboration

Nicolas Lanthier 1 collaboration

Naim Alkhouri 1 collaboration

Christophe Moreno 1 collaboration

Jörn M Schattenberg 1 collaboration

Diana Stefanova-Petrova 1 collaboration

Luisa Vonghia 1 collaboration

Régine Rouzier 1 collaboration

Maeva Guillaume 1 collaboration

Alexander Hodge 1 collaboration

Manuel Romero-Gómez 1 collaboration

Marie-Paule Richard 1 collaboration

None None 1 collaboration

Emma Derrett-Smith 1 collaboration

Kristina E N Clark 1 collaboration

Xu Shiwen 1 collaboration

David J Abraham 1 collaboration

Rachel K Hoyles 1 collaboration

Jean Louis Junien 1 collaboration

Irena Konstantinova 1 collaboration

Voon H Ong 1 collaboration

Christopher P Denton 1 collaboration

Young Bae Sohn 1 collaboration

Raymond Wang 1 collaboration

Jane Ashworth 1 collaboration

Erin Jozwiak 1 collaboration

Laura Pollard 1 collaboration

Timothy C Wood 1 collaboration

Tariq Aslam 1 collaboration

Paul R Harmatz 1 collaboration