Philip Reigan

Affiliations

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Denver, CO, United States.

Publications (23)

A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.

Frontiers in immunology

Avec: Savannah M Rocha , Anna C Fagre , Amanda S Latham , Jason E Cummings , Tawfik A Aboellail , Devin A Aldaz , Casey P McDermott , Katriana A Popichak , Rebekah C Kading , Tony Schountz , Neil D Theise , Richard A Slayden , Ronald B Tjalkens

Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface.

Frontiers in cell and developmental biology

Avec: Alya Hussain , Vu T Nguyen , Michael McMurray

The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.

Structure (London, England : 1993)

Avec: Daniel R Eiler , Brian T Wimberly , Danielle Y Bilodeau , J Matthew Taliaferro , Olivia S Rissland , Jeffrey S Kieft

Maneb alters central carbon metabolism and thiol redox status in a toxicant model of Parkinson's disease.

Free radical biology & medicine

Avec: Colin C Anderson , John O Marentette , Abhishek K Rauniyar , Kendra M Prutton , Meera Khatri , Chris Matheson , Julie A Reisz , Angelo D'Alessandro , James R Roede

Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo.

Molecular carcinogenesis

Avec: Hannah M Hicks , Logan R McKenna , Veronica L Espinoza , Nikita Pozdeyev , Laura A Pike , Sharon B Sams , Daniel LaBarbera , Christopher D Raeburn , Rebecca E Schweppe

N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors.

Bioorganic & medicinal chemistry

Avec: Kimberly A Casalvieri , Christopher J Matheson , Becka M Warfield , Donald S Backos ,

Neuroprotective Efficacy of the Glucocorticoid Receptor Modulator PT150 in the Rotenone Mouse Model of Parkinson's Disease.

Neurotoxicology

Avec: Amanda S Latham , Savannah M Rocha , Casey P McDermott , Richard A Slayden , Ronald B Tjalkens

The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.

Blood

Avec: Maria L Amaya , Anagha Inguva , Shanshan Pei , Courtney Jones , Anna Krug , Haobin Ye , Mohammad Minhajuddin , Amanda Winters , Steffanie L Furtek , Fabia Gamboni , Brett Stevens , Angelo D'Alessandro , Daniel A Pollyea , Craig T Jordan

Multifunctional role of thymidine phosphorylase in cancer.

Trends in cancer

Avec: Becka M Warfield ,

10-Alkoxy-anthracenyl-isoxazole analogs have sub-micromolar activity against a Glioblastoma multiforme cell line.

Bioorganic & medicinal chemistry

Avec: Nathan S Duncan , Michael J Campbell , Donald S Backos , Chun Li , Kevin C Rider , Sascha Stump , Matthew J Weaver , Mariusz P Gajewski , Howard D Beall , Nicholas R Natale

The Lateral Metalation of Isoxazolo[3,4-

Molecules (Basel, Switzerland)

Avec: Christina A Gates , Donald S Backos , Nicholas R Natale

Molecular docking of substituted pteridinones and pyrimidines to the ATP-binding site of the N-terminal domain of RSK2 and associated MM/GBSA and molecular field datasets.

Data in brief

Avec: Kimberly A Casalvieri , Christopher J Matheson , Donald S Backos ,

Evaluation of Thymidine Phosphorylase Inhibitors in Glioblastoma and Their Capacity for Temozolomide Potentiation.

ACS chemical neuroscience

Avec: Becka M Warfield , Christopher J Matheson , Debbie G McArthur , Donald S Backos ,

Using Synthetic ApoC-II Peptides and nAngptl4 Fragments to Measure Lipoprotein Lipase Activity in Radiometric and Fluorescent Assays.

Frontiers in cardiovascular medicine

Avec: Dean Oldham , Hong Wang , Juliet Mullen , Emma Lietzke , Kayla Sprenger , Robert H Eckel , Kimberley D Bruce

Identification of PARN nuclease activity inhibitors by computational-based docking and high-throughput screening.

Scientific reports

Avec: Thao Ngoc Huynh , Siddharth Shukla , Roy Parker

Neuroprotective Efficacy of the Glucocorticoid Receptor Modulator PT150 in the Rotenone Mouse Model of Parkinson's Disease.

bioRxiv : the preprint server for biology

Avec: Amanda S Latham , Savannah M Rocha , Casey P McDermott , Richard A Slayden , Ronald B Tjalkens

10-N-heterocylic aryl-isoxazole-amides (AIMs) have robust anti-tumor activity against breast and brain cancer cell lines and useful fluorescence properties.

Bioorganic & medicinal chemistry

Avec: Matthew J Weaver , Sascha Stump , Michael J Campbell , Donald S Backos , Chun Li , Earle Adams , Howard D Beall , Nicholas R Natale

Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk.

International journal of molecular sciences

Avec: Kimberley D Bruce , Maoping Tang , Robert H Eckel

Establishment and Characterization of Four Novel Thyroid Cancer Cell Lines and PDX Models Expressing the RET/PTC1 Rearrangement, BRAFV600E, or RASQ61R as Drivers.

Molecular cancer research : MCR

Avec: Rebecca E Schweppe , Nikita Pozdeyev , Laura A Pike , Christopher Korch , Qiong Zhou , Sharon B Sams , Vibha Sharma , Umarani Pugazhenthi , Christopher Raeburn , Maria B Albuja-Cruz , Daniel V LaBarbera , Iñigo Landa , Jeffrey A Knauf , James A Fagin , Bryan R Haugen

Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity study.

Bioorganic & medicinal chemistry

Avec: Kimberly A Casalvieri , Christopher J Matheson , Donald S Backos ,

Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors.

European journal of medicinal chemistry

Avec: Christopher J Matheson , Kimberly A Casalvieri , Donald S Backos , Mohammed Minhajuddin , Craig T Jordan ,

Substituted pteridinones, pyrimidines, pyrrolopyrimidines, and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors: Pharmacophore modeling data.

Data in brief

Avec: Becka M Warfield , Kimberly A Casalvieri , Christopher J Matheson , Donald S Backos ,

Auriculocondylar syndrome 2 results from the dominant-negative action of PLCB4 variants.

Disease models & mechanisms

Avec: Stanley M Kanai , Caleb Heffner , Timothy C Cox , Michael L Cunningham , Francisco A Perez , Aaron M Bauer , Cristan Carter , Stephen A Murray , David E Clouthier

Réseau de co-auteurs

Donald S Backos 9 collaborations

Christopher J Matheson 6 collaborations

Kimberly A Casalvieri 5 collaborations

Becka M Warfield 4 collaborations

Savannah M Rocha 3 collaborations

Amanda S Latham 3 collaborations

Casey P McDermott 3 collaborations

Richard A Slayden 3 collaborations

Ronald B Tjalkens 3 collaborations

Nicholas R Natale 3 collaborations

Angelo D'Alessandro 2 collaborations

Nikita Pozdeyev 2 collaborations

Laura A Pike 2 collaborations

Sharon B Sams 2 collaborations

Rebecca E Schweppe 2 collaborations

Craig T Jordan 2 collaborations

Michael J Campbell 2 collaborations

Chun Li 2 collaborations

Sascha Stump 2 collaborations

Matthew J Weaver 2 collaborations

Howard D Beall 2 collaborations

Robert H Eckel 2 collaborations

Kimberley D Bruce 2 collaborations

Anna C Fagre 1 collaboration

Jason E Cummings 1 collaboration

Tawfik A Aboellail 1 collaboration

Devin A Aldaz 1 collaboration

Katriana A Popichak 1 collaboration

Rebekah C Kading 1 collaboration

Tony Schountz 1 collaboration

Neil D Theise 1 collaboration

Alya Hussain 1 collaboration

Vu T Nguyen 1 collaboration

Michael McMurray 1 collaboration

Daniel R Eiler 1 collaboration

Brian T Wimberly 1 collaboration

Danielle Y Bilodeau 1 collaboration

J Matthew Taliaferro 1 collaboration

Olivia S Rissland 1 collaboration

Jeffrey S Kieft 1 collaboration

Colin C Anderson 1 collaboration

John O Marentette 1 collaboration

Abhishek K Rauniyar 1 collaboration

Kendra M Prutton 1 collaboration

Meera Khatri 1 collaboration

Chris Matheson 1 collaboration

Julie A Reisz 1 collaboration

James R Roede 1 collaboration

Hannah M Hicks 1 collaboration

Logan R McKenna 1 collaboration

Veronica L Espinoza 1 collaboration

Daniel LaBarbera 1 collaboration

Christopher D Raeburn 1 collaboration

Maria L Amaya 1 collaboration

Anagha Inguva 1 collaboration

Shanshan Pei 1 collaboration

Courtney Jones 1 collaboration

Anna Krug 1 collaboration

Haobin Ye 1 collaboration

Mohammad Minhajuddin 1 collaboration

Amanda Winters 1 collaboration

Steffanie L Furtek 1 collaboration

Fabia Gamboni 1 collaboration

Brett Stevens 1 collaboration

Daniel A Pollyea 1 collaboration

Nathan S Duncan 1 collaboration

Kevin C Rider 1 collaboration

Mariusz P Gajewski 1 collaboration

Christina A Gates 1 collaboration

Debbie G McArthur 1 collaboration

Dean Oldham 1 collaboration

Hong Wang 1 collaboration

Juliet Mullen 1 collaboration

Emma Lietzke 1 collaboration

Kayla Sprenger 1 collaboration

Thao Ngoc Huynh 1 collaboration

Siddharth Shukla 1 collaboration

Roy Parker 1 collaboration

Earle Adams 1 collaboration

Maoping Tang 1 collaboration

Christopher Korch 1 collaboration

Qiong Zhou 1 collaboration

Vibha Sharma 1 collaboration

Umarani Pugazhenthi 1 collaboration

Christopher Raeburn 1 collaboration

Maria B Albuja-Cruz 1 collaboration

Daniel V LaBarbera 1 collaboration

Iñigo Landa 1 collaboration

Jeffrey A Knauf 1 collaboration

James A Fagin 1 collaboration

Bryan R Haugen 1 collaboration

Mohammed Minhajuddin 1 collaboration

Stanley M Kanai 1 collaboration

Caleb Heffner 1 collaboration

Timothy C Cox 1 collaboration

Michael L Cunningham 1 collaboration

Francisco A Perez 1 collaboration

Aaron M Bauer 1 collaboration

Cristan Carter 1 collaboration

Stephen A Murray 1 collaboration

David E Clouthier 1 collaboration