Nicolὸ Riggi

Affiliations

Institute of Pathology, Department of Experimental Pathology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, 1011 Lausanne, Switzerland.

Publications (24)

Correction to: Preclinical Evaluation and Dosimetry of [

Molecular imaging and biology

Avec: Francesco Cicone , Thibaut Denoël , Silvano Gnesin , Nicolo Riggi , Melita Irving , Gopinadh Jakka , Niklaus Schaefer , David Viertl , George Coukos , John O Prior

EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors.

Nature communications

Avec: Gaylor Boulay , Liliane C Broye , Rui Dong , Sowmya Iyer , Rajendran Sanalkumar , Yu-Hang Xing , Rémi Buisson , Shruthi Rengarajan , Beverly Naigles , Benoît Duc , Angela Volorio , Mary E Awad , Raffaele Renella , Ivan Chebib , G Petur Nielsen , Edwin Choy , Gregory M Cote , Lee Zou , Igor Letovanec , Ivan Stamenkovic , Miguel N Rivera , Nicolò Riggi

Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity.

Cancer research

Avec: Johannes C Melms , Sreeram Vallabhaneni , Caitlin E Mills , Clarence Yapp , Jia-Yun Chen , Eugenio Morelli , Patricia Waszyk , Sushil Kumar , Derrick Deming , Nienke Moret , Steven Rodriguez , Kartik Subramanian , Meri Rogava , Adam N R Cartwright , Adrienne Luoma , Shaolin Mei , Titus J Brinker , David M Miller , Alexander Spektor , Dirk Schadendorf , Nicolo Riggi , Kai W Wucherpfennig , Peter K Sorger , Benjamin Izar

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.

Nature medicine

Avec: Livnat Jerby-Arnon , Cyril Neftel , Marni E Shore , Hannah R Weisman , Nathan D Mathewson , Matthew J McBride , Brian Haas , Benjamin Izar , Angela Volorio , Gaylor Boulay , Luisa Cironi , Alyssa R Richman , Liliane C Broye , Joseph M Gurski , Christina C Luo , Ravindra Mylvaganam , Lan Nguyen , Shaolin Mei , Johannes C Melms , Christophe Georgescu , Ofir Cohen , Jorge E Buendia-Buendia , Asa Segerstolpe , Malika Sud , Michael S Cuoco , Danny Labes , Simon Gritsch , Daniel R Zollinger , Nicole Ortogero , Joseph M Beechem , G Petur Nielsen , Ivan Chebib , Tu Nguyen-Ngoc , Michael Montemurro , Gregory M Cote , Edwin Choy , Igor Letovanec , Stéphane Cherix , Nikhil Wagle , Peter K Sorger , Alex B Haynes , John T Mullen , Ivan Stamenkovic , Miguel N Rivera , Cigall Kadoch , Kai W Wucherpfennig , Orit Rozenblatt-Rosen , Mario L Suvà , Nicolò Riggi , Aviv Regev

Genomic and transcriptomic landscape of conjunctival melanoma.

PLoS genetics

Avec: Katarina Cisarova , Marc Folcher , Ikram El Zaoui , Rosanna Pescini-Gobert , Virginie G Peter , Beryl Royer-Bertrand , Leonidas Zografos , Ann Schalenbourg , Michael Nicolas , Donata Rimoldi , Serge Leyvraz , Nicolò Riggi , Alexandre P Moulin , Carlo Rivolta

5-Hydroxymethylcytosine Loss in Conjunctival Melanoma.

Dermatopathology (Basel, Switzerland)

Avec: Alexandre Stahl , Nicolo Riggi , Katya Nardou , Michael Nicolas , Gurkan Kaya , Alexandre Moulin

A live single-cell reporter assay links intratumor heterogeneity to metastatic proclivity in Ewing sarcoma.

Science advances

Avec: Tugba Keskin , Beatrice Rucci , Sandrine Cornaz-Buros , Patricia Martin , Carlo Fusco , Liliane Broye , Katarina Cisarova , Elizabeth M Perez , Igor Letovanec , Stefano La Rosa , Stephane Cherix , Manuel Diezi , Raffaele Renella , Paolo Provero , Mario L Suvà , Ivan Stamenkovic , Nicolò Riggi

Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma.

JCI insight

Avec: Santhoshkumar Sundaramoorthy , Daniele Filippo Colombo , Rajendran Sanalkumar , Liliane Broye , Katia Balmas Bourloud , Gaylor Boulay , Luisa Cironi , Ivan Stamenkovic , Raffaele Renella , Fabien Kuttler , Gerardo Turcatti , Miguel N Rivera , Annick Mühlethaler-Mottet , Anaïs Flore Bardet , Nicolò Riggi

Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis.

Life science alliance

Avec: Sampath Katakam , Santosh Anand , Patricia Martin , Nicolo Riggi , Ivan Stamenkovic

TWIST1 expression is associated with high-risk neuroblastoma and promotes primary and metastatic tumor growth.

Communications biology

Avec: Maria-Vittoria Sepporta , Viviane Praz , Katia Balmas Bourloud , Jean-Marc Joseph , Nicolas Jauquier , Nicolò Riggi , Katya Nardou-Auderset , Audrey Petit , Jean-Yves Scoazec , Hervé Sartelet , Raffaele Renella , Annick Mühlethaler-Mottet

Identification of New Vulnerabilities in Conjunctival Melanoma Using Image-Based High Content Drug Screening.

Cancers

Avec: Katya Nardou , Michael Nicolas , Fabien Kuttler , Katarina Cisarova , Elifnaz Celik , Mathieu Quinodoz , Nicolo Riggi , Olivier Michielin , Carlo Rivolta , Gerardo Turcatti , Alexandre Pierre Moulin

Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors.

Cell genomics

Avec: Y Esther Tak , Gaylor Boulay , Lukuo Lee , Sowmya Iyer , Nicholas T Perry , Hayley T Schultz , Sara P Garcia , Liliane Broye , Joy E Horng , Shruthi Rengarajan , Beverly Naigles , Angela Volorio , Jeffry D Sander , Jingyi Gong , J Keith Joung , Miguel N Rivera

Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity.

Science advances

Avec: Rajendran Sanalkumar , Rui Dong , Lukuo Lee , Yu-Hang Xing , Sowmya Iyer , Igor Letovanec , Stefano La Rosa , Giovanna Finzi , Elettra Musolino , Roberto Papait , Ivan Chebib , G Petur Nielsen , Raffaele Renella , Gregory M Cote , Edwin Choy , Martin Aryee , Kimberly Stegmaier , Ivan Stamenkovic , Miguel N Rivera , Nicolò Riggi

Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma.

Cell genomics

Avec: Samantha M Bevill , Salvador Casaní-Galdón , Chadi A El Farran , Eli G Cytrynbaum , Kevin A Macias , Sylvie E Oldeman , Kayla J Oliveira , Molly M Moore , Esmat Hegazi , Carmen Adriaens , Fadi J Najm , George D Demetri , Sonia Cohen , John T Mullen , Nicolò Riggi , Sarah E Johnstone , Bradley E Bernstein

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.

Cell

Avec: Cyril Neftel , Julie Laffy , Mariella G Filbin , Toshiro Hara , Marni E Shore , Gilbert J Rahme , Alyssa R Richman , Dana Silverbush , McKenzie L Shaw , Christine M Hebert , John Dewitt , Simon Gritsch , Elizabeth M Perez , L Nicolas Gonzalez Castro , Xiaoyang Lan , Nicholas Druck , Christopher Rodman , Danielle Dionne , Alexander Kaplan , Mia S Bertalan , Julia Small , Kristine Pelton , Sarah Becker , Dennis Bonal , Quang-De Nguyen , Rachel L Servis , Jeremy M Fung , Ravindra Mylvaganam , Lisa Mayr , Johannes Gojo , Christine Haberler , Rene Geyeregger , Thomas Czech , Irene Slavc , Brian V Nahed , William T Curry , Bob S Carter , Hiroaki Wakimoto , Priscilla K Brastianos , Tracy T Batchelor , Anat Stemmer-Rachamimov , Maria Martinez-Lage , Matthew P Frosch , Ivan Stamenkovic , Nicolo Riggi , Esther Rheinbay , Michelle Monje , Orit Rozenblatt-Rosen , Daniel P Cahill , Anoop P Patel , Tony Hunter , Inder M Verma , Keith L Ligon , David N Louis , Aviv Regev , Bradley E Bernstein , Itay Tirosh , Mario L Suvà

β-Catenin Expression and Activation in Conjunctival Melanoma.

Dermatopathology (Basel, Switzerland)

Avec: Emerentienne Larivé , Michael Nicolas , Gürkan Kaya , Nicolo Riggi , Alexandre P Moulin

EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma.

Nature communications

Avec: Emely Möller , Viviane Praz , Sanalkumar Rajendran , Rui Dong , Alexandra Cauderay , Yu-Hang Xing , Lukuo Lee , Carlo Fusco , Liliane C Broye , Luisa Cironi , Sowmya Iyer , Shruthi Rengarajan , Mary E Awad , Beverly Naigles , Igor Letovanec , Nicola Ormas , Giovanna Finzi , Stefano La Rosa , Fausto Sessa , Ivan Chebib , G Petur Nielsen , Antonia Digklia , Dimitrios Spentzos , Gregory M Cote , Edwin Choy , Martin Aryee , Ivan Stamenkovic , Gaylor Boulay , Miguel N Rivera , Nicolò Riggi

CIC-DUX4 Chromatin Profiling Reveals New Epigenetic Dependencies and Actionable Therapeutic Targets in CIC-Rearranged Sarcomas.

Cancers

Avec: Arnaud Bakaric , Luisa Cironi , Viviane Praz , Rajendran Sanalkumar , Liliane C Broye , Kerria Favre-Bulle , Igor Letovanec , Antonia Digklia , Raffaele Renella , Ivan Stamenkovic , Christopher J Ott , Takuro Nakamura , Cristina R Antonescu , Miguel N Rivera , Nicolò Riggi

Clear cell sarcoma: state-of-the art and perspectives.

Expert review of anticancer therapy

Avec: Laureline Wetterwald , Nicolò Riggi , Anastasios Kyriazoglou , Giovanni Dei Tos , Angelo Dei Tos , Antonia Digklia

Nongenetic Evolution Drives Lung Adenocarcinoma Spatial Heterogeneity and Progression.

Cancer discovery

Avec: Daniele Tavernari , Elena Battistello , Elie Dheilly , Aaron S Petruzzella , Marco Mina , Jessica Sordet-Dessimoz , Solange Peters , Thorsten Krueger , David Gfeller , Nicolo Riggi , Elisa Oricchio , Igor Letovanec , Giovanni Ciriello

The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.

Life science alliance

Avec: Gaylor Boulay , Luisa Cironi , Sara P Garcia , Shruthi Rengarajan , Yu-Hang Xing , Lukuo Lee , Mary E Awad , Beverly Naigles , Sowmya Iyer , Liliane C Broye , Tugba Keskin , Alexandra Cauderay , Carlo Fusco , Igor Letovanec , Ivan Chebib , Petur Gunnalugur Nielsen , Stéphane Tercier , Stéphane Cherix , Tu Nguyen-Ngoc , Gregory Cote , Edwin Choy , Paolo Provero , Mario L Suvà , Miguel N Rivera , Ivan Stamenkovic , Nicolò Riggi

Conjunctival Melanoma Targeted Therapy: MAPK and PI3K/mTOR Pathways Inhibition.

Investigative ophthalmology & visual science

Avec: Ikram El Zaoui , Maya Bucher , Donata Rimoldi , Michael Nicolas , Gurkan Kaya , Rosanna Pescini Gobert , Nicola Bedoni , Ann Schalenbourg , Ezziat Sakina , Leonidas Zografos , Serge Leyvraz , Nicolo Riggi , Carlo Rivolta , Alexandre P Moulin

Preclinical Evaluation and Dosimetry of [

Molecular imaging and biology

Avec: Francesco Cicone , Thibaut Denoël , Silvano Gnesin , Nicolo Riggi , Melita Irving , Gopinadh Jakka , Niklaus Schaefer , David Viertl , George Coukos , John O Prior

LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability.

Cell reports

Avec: Tugba Keskin , Arnaud Bakaric , Patricia Waszyk , Gaylor Boulay , Matteo Torsello , Sandrine Cornaz-Buros , Nadja Chevalier , Thibaud Geiser , Patricia Martin , Angela Volorio , Sowmya Iyer , Anupriya Kulkarni , Igor Letovanec , Stéphane Cherix , Gregory M Cote , Edwin Choy , Antonia Digklia , Michael Montemurro , Ivan Chebib , Petur G Nielsen , Angel M Carcaboso , Jaume Mora , Raffaele Renella , Mario L Suvà , Carlo Fusco , Paolo Provero , Miguel N Rivera , Nicolò Riggi , Ivan Stamenkovic

Réseau de co-auteurs

Nicolò Riggi 13 collaborations

Ivan Stamenkovic 11 collaborations

Nicolo Riggi 10 collaborations

Igor Letovanec 9 collaborations

Miguel N Rivera 9 collaborations

Gaylor Boulay 7 collaborations

Raffaele Renella 7 collaborations

Sowmya Iyer 6 collaborations

Ivan Chebib 6 collaborations

Edwin Choy 6 collaborations

Liliane C Broye 5 collaborations

Gregory M Cote 5 collaborations

Luisa Cironi 5 collaborations

Mario L Suvà 5 collaborations

Michael Nicolas 5 collaborations

Rajendran Sanalkumar 4 collaborations

Yu-Hang Xing 4 collaborations

Shruthi Rengarajan 4 collaborations

Beverly Naigles 4 collaborations

Angela Volorio 4 collaborations

G Petur Nielsen 4 collaborations

Carlo Fusco 4 collaborations

Lukuo Lee 4 collaborations

Antonia Digklia 4 collaborations

Rui Dong 3 collaborations

Mary E Awad 3 collaborations

Stéphane Cherix 3 collaborations

Katarina Cisarova 3 collaborations

Alexandre P Moulin 3 collaborations

Carlo Rivolta 3 collaborations

Tugba Keskin 3 collaborations

Patricia Martin 3 collaborations

Liliane Broye 3 collaborations

Stefano La Rosa 3 collaborations

Paolo Provero 3 collaborations

Viviane Praz 3 collaborations

Francesco Cicone 2 collaborations

Thibaut Denoël 2 collaborations

Silvano Gnesin 2 collaborations

Melita Irving 2 collaborations

Gopinadh Jakka 2 collaborations

Niklaus Schaefer 2 collaborations

David Viertl 2 collaborations

George Coukos 2 collaborations

John O Prior 2 collaborations

Johannes C Melms 2 collaborations

Patricia Waszyk 2 collaborations

Shaolin Mei 2 collaborations

Kai W Wucherpfennig 2 collaborations

Peter K Sorger 2 collaborations

Benjamin Izar 2 collaborations

Cyril Neftel 2 collaborations

Marni E Shore 2 collaborations

Alyssa R Richman 2 collaborations

Ravindra Mylvaganam 2 collaborations

Simon Gritsch 2 collaborations

Tu Nguyen-Ngoc 2 collaborations

Michael Montemurro 2 collaborations

John T Mullen 2 collaborations

Orit Rozenblatt-Rosen 2 collaborations

Aviv Regev 2 collaborations

Ikram El Zaoui 2 collaborations

Leonidas Zografos 2 collaborations

Ann Schalenbourg 2 collaborations

Donata Rimoldi 2 collaborations

Serge Leyvraz 2 collaborations

Katya Nardou 2 collaborations

Gurkan Kaya 2 collaborations

Sandrine Cornaz-Buros 2 collaborations

Elizabeth M Perez 2 collaborations

Katia Balmas Bourloud 2 collaborations

Fabien Kuttler 2 collaborations

Gerardo Turcatti 2 collaborations

Annick Mühlethaler-Mottet 2 collaborations

Sara P Garcia 2 collaborations

Giovanna Finzi 2 collaborations

Martin Aryee 2 collaborations

Bradley E Bernstein 2 collaborations

Alexandra Cauderay 2 collaborations

Arnaud Bakaric 2 collaborations

Rémi Buisson 1 collaboration

Benoît Duc 1 collaboration

Lee Zou 1 collaboration

Sreeram Vallabhaneni 1 collaboration

Caitlin E Mills 1 collaboration

Clarence Yapp 1 collaboration

Jia-Yun Chen 1 collaboration

Eugenio Morelli 1 collaboration

Sushil Kumar 1 collaboration

Derrick Deming 1 collaboration

Nienke Moret 1 collaboration

Steven Rodriguez 1 collaboration

Kartik Subramanian 1 collaboration

Meri Rogava 1 collaboration

Adam N R Cartwright 1 collaboration

Adrienne Luoma 1 collaboration

Titus J Brinker 1 collaboration

David M Miller 1 collaboration

Alexander Spektor 1 collaboration

Dirk Schadendorf 1 collaboration

Livnat Jerby-Arnon 1 collaboration

Hannah R Weisman 1 collaboration

Nathan D Mathewson 1 collaboration

Matthew J McBride 1 collaboration

Brian Haas 1 collaboration

Joseph M Gurski 1 collaboration

Christina C Luo 1 collaboration

Lan Nguyen 1 collaboration

Christophe Georgescu 1 collaboration

Ofir Cohen 1 collaboration

Jorge E Buendia-Buendia 1 collaboration

Asa Segerstolpe 1 collaboration

Malika Sud 1 collaboration

Michael S Cuoco 1 collaboration

Danny Labes 1 collaboration

Daniel R Zollinger 1 collaboration

Nicole Ortogero 1 collaboration

Joseph M Beechem 1 collaboration

Nikhil Wagle 1 collaboration

Alex B Haynes 1 collaboration

Cigall Kadoch 1 collaboration

Marc Folcher 1 collaboration

Rosanna Pescini-Gobert 1 collaboration

Virginie G Peter 1 collaboration

Beryl Royer-Bertrand 1 collaboration

Alexandre Stahl 1 collaboration

Alexandre Moulin 1 collaboration

Beatrice Rucci 1 collaboration

Stephane Cherix 1 collaboration

Manuel Diezi 1 collaboration

Santhoshkumar Sundaramoorthy 1 collaboration

Daniele Filippo Colombo 1 collaboration

Anaïs Flore Bardet 1 collaboration

Sampath Katakam 1 collaboration

Santosh Anand 1 collaboration

Maria-Vittoria Sepporta 1 collaboration

Jean-Marc Joseph 1 collaboration

Nicolas Jauquier 1 collaboration

Katya Nardou-Auderset 1 collaboration

Audrey Petit 1 collaboration

Jean-Yves Scoazec 1 collaboration

Hervé Sartelet 1 collaboration

Elifnaz Celik 1 collaboration

Mathieu Quinodoz 1 collaboration

Olivier Michielin 1 collaboration

Alexandre Pierre Moulin 1 collaboration

Y Esther Tak 1 collaboration

Nicholas T Perry 1 collaboration

Hayley T Schultz 1 collaboration

Joy E Horng 1 collaboration

Jeffry D Sander 1 collaboration

Jingyi Gong 1 collaboration

J Keith Joung 1 collaboration

Elettra Musolino 1 collaboration

Roberto Papait 1 collaboration

Kimberly Stegmaier 1 collaboration

Samantha M Bevill 1 collaboration

Salvador Casaní-Galdón 1 collaboration

Chadi A El Farran 1 collaboration

Eli G Cytrynbaum 1 collaboration

Kevin A Macias 1 collaboration

Sylvie E Oldeman 1 collaboration

Kayla J Oliveira 1 collaboration

Molly M Moore 1 collaboration

Esmat Hegazi 1 collaboration

Carmen Adriaens 1 collaboration

Fadi J Najm 1 collaboration

George D Demetri 1 collaboration

Sonia Cohen 1 collaboration

Sarah E Johnstone 1 collaboration

Julie Laffy 1 collaboration

Mariella G Filbin 1 collaboration

Toshiro Hara 1 collaboration

Gilbert J Rahme 1 collaboration

Dana Silverbush 1 collaboration

McKenzie L Shaw 1 collaboration

Christine M Hebert 1 collaboration

John Dewitt 1 collaboration

L Nicolas Gonzalez Castro 1 collaboration

Xiaoyang Lan 1 collaboration

Nicholas Druck 1 collaboration

Christopher Rodman 1 collaboration

Danielle Dionne 1 collaboration

Alexander Kaplan 1 collaboration

Mia S Bertalan 1 collaboration

Julia Small 1 collaboration

Kristine Pelton 1 collaboration

Sarah Becker 1 collaboration

Dennis Bonal 1 collaboration

Quang-De Nguyen 1 collaboration

Rachel L Servis 1 collaboration

Jeremy M Fung 1 collaboration

Lisa Mayr 1 collaboration

Johannes Gojo 1 collaboration

Christine Haberler 1 collaboration

Rene Geyeregger 1 collaboration

Thomas Czech 1 collaboration

Irene Slavc 1 collaboration

Brian V Nahed 1 collaboration

William T Curry 1 collaboration

Bob S Carter 1 collaboration

Hiroaki Wakimoto 1 collaboration

Priscilla K Brastianos 1 collaboration

Tracy T Batchelor 1 collaboration

Anat Stemmer-Rachamimov 1 collaboration

Maria Martinez-Lage 1 collaboration

Matthew P Frosch 1 collaboration

Esther Rheinbay 1 collaboration

Michelle Monje 1 collaboration

Daniel P Cahill 1 collaboration

Anoop P Patel 1 collaboration

Tony Hunter 1 collaboration

Inder M Verma 1 collaboration

Keith L Ligon 1 collaboration

David N Louis 1 collaboration

Itay Tirosh 1 collaboration

Emerentienne Larivé 1 collaboration

Gürkan Kaya 1 collaboration

Emely Möller 1 collaboration

Sanalkumar Rajendran 1 collaboration

Nicola Ormas 1 collaboration

Fausto Sessa 1 collaboration

Dimitrios Spentzos 1 collaboration

Kerria Favre-Bulle 1 collaboration

Christopher J Ott 1 collaboration

Takuro Nakamura 1 collaboration

Cristina R Antonescu 1 collaboration

Laureline Wetterwald 1 collaboration

Anastasios Kyriazoglou 1 collaboration

Giovanni Dei Tos 1 collaboration

Angelo Dei Tos 1 collaboration

Daniele Tavernari 1 collaboration

Elena Battistello 1 collaboration

Elie Dheilly 1 collaboration

Aaron S Petruzzella 1 collaboration

Marco Mina 1 collaboration

Jessica Sordet-Dessimoz 1 collaboration

Solange Peters 1 collaboration

Thorsten Krueger 1 collaboration

David Gfeller 1 collaboration

Elisa Oricchio 1 collaboration

Giovanni Ciriello 1 collaboration

Petur Gunnalugur Nielsen 1 collaboration

Stéphane Tercier 1 collaboration

Gregory Cote 1 collaboration

Maya Bucher 1 collaboration

Rosanna Pescini Gobert 1 collaboration

Nicola Bedoni 1 collaboration

Ezziat Sakina 1 collaboration

Matteo Torsello 1 collaboration

Nadja Chevalier 1 collaboration

Thibaud Geiser 1 collaboration

Anupriya Kulkarni 1 collaboration

Petur G Nielsen 1 collaboration

Angel M Carcaboso 1 collaboration

Jaume Mora 1 collaboration