Martin L Sos

Affiliations

Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany. martin.sos@uni-koeln.de.
Department of Translational Genomics, Center of Integrated Oncology Cologne‑Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany. martin.sos@uni-koeln.de.
Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany. martin.sos@uni-koeln.de.

ORCID: http://orcid.org/0000-0002-2868-100X

Publications (15)

The next tier of EGFR resistance mutations in lung cancer.

Oncogene

Avec: Hannah L Tumbrink , Alena Heimsoeth ,

New Approaches to SCLC Therapy: From the Laboratory to the Clinic.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: John T Poirier , Julie George , Taofeek K Owonikoko , Anton Berns , Elisabeth Brambilla , Lauren A Byers , David Carbone , Huanhuan J Chen , Camilla L Christensen , Caroline Dive , Anna F Farago , Ramaswamy Govindan , Christine Hann , Matthew D Hellmann , Leora Horn , Jane E Johnson , Young S Ju , Sumin Kang , Mark Krasnow , James Lee , Se-Hoon Lee , Jonathan Lehman , Benjamin Lok , Christine Lovly , David MacPherson , David McFadden , John Minna , Matthew Oser , Keunchil Park , Kwon-Sik Park , Yves Pommier , Vito Quaranta , Neal Ready , Julien Sage , Giorgio Scagliotti , Kate D Sutherland , William D Travis , Christopher R Vakoc , Sarah J Wait , Ignacio Wistuba , Kwok Kin Wong , Hua Zhang , Jillian Daigneault , Jacinta Wiens , Charles M Rudin , Trudy G Oliver

Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer.

NPJ precision oncology

Avec: Diana Schaufler , David F Ast , Hannah L Tumbrink , Nima Abedpour , Lukas Maas , Ayla E Schwäbe , Inga Spille , Stefanie Lennartz , Jana Fassunke , Mihaela Aldea , Benjamin Besse , David Planchard , Lucia Nogova , Sebastian Michels , Carsten Kobe , Thorsten Persigehl , Theresa Westphal , Sophia Koleczko , Rieke Fischer , Jan-Phillip Weber , Janine Altmüller , Roman K Thomas , Sabine Merkelbach-Bruse , Oliver Gautschi , Laura Mezquita , Reinhard Büttner , Jürgen Wolf , Martin Peifer , Johannes Brägelmann , Matthias Scheffler ,

Resistance to MET inhibition in MET-dependent NSCLC and therapeutic activity after switching from type I to type II MET inhibitors.

European journal of cancer (Oxford, England : 1990)

Avec: Richard Riedel , Jana Fassunke , Hannah L Tumbrink , Andreas H Scheel , Carina Heydt , Lena Hieggelke , Matthias Scheffler , Alena Heimsoeth , Lucia Nogova , Sebastian Michels , Jan-Phillip Weber , Rieke N Fischer , Anna Eisert , Theresa Westphal , Diana Schaufler , Janna Siemanowski , Michaela A Ihle , Svenja Wagener-Ryczek , Roberta Castiglione , Roberto Pappesch , Jan Rehker , Jessica Jürgens , Erich Stoelben , Anne Bunck , Carsten Kobe , Sabine Merkelbach-Bruse , Reinhard Büttner , Jürgen Wolf

K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Matthias Scheffler , Michaela A Ihle , Rebecca Hein , Sabine Merkelbach-Bruse , Andreas H Scheel , Janna Siemanowski , Johannes Brägelmann , Anna Kron , Nima Abedpour , Frank Ueckeroth , Merle Schüller , Sophia Koleczko , Sebastian Michels , Jana Fassunke , Helen Pasternack , Carina Heydt , Monika Serke , Rieke Fischer , Wolfgang Schulte , Ulrich Gerigk , Lucia Nogova , Yon-Dschun Ko , Diana S Y Abdulla , Richard Riedel , Karl-Otto Kambartel , Joachim Lorenz , Imke Sauerland , Winfried Randerath , Britta Kaminsky , Lars Hagmeyer , Christian Grohé , Anna Eisert , Rieke Frank , Leonie Gogl , Carsten Schaepers , Alessandra Holzem , Martin Hellmich , Roman K Thomas , Martin Peifer , Reinhard Büttner , Jürgen Wolf

Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.

Journal of medicinal chemistry

Avec: Jonas Lategahn , Hannah L Tumbrink , Carsten Schultz-Fademrecht , Alena Heimsoeth , Lisa Werr , Janina Niggenaber , Marina Keul , Fatma Parmaksiz , Matthias Baumann , Sascha Menninger , Eldar Zent , Ina Landel , Jörn Weisner , Kirujan Jeyakumar , Leonie Heyden , Nicole Russ , Fabienne Müller , Carina Lorenz , Johannes Brägelmann , Inga Spille , Tobias Grabe , Matthias P Müller , Johannes M Heuckmann , Bert M Klebl , Peter Nussbaumer , Daniel Rauh

Report of the First International Symposium on NUT Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Christopher A French , Michael L Cheng , Glenn J Hanna , Steven G DuBois , Nicole G Chau , Christine L Hann , Simone Storck , Ravi Salgia , Matteo Trucco , Jennifer Tseng , Anastasios Stathis , Richard Piekarz , Ulrich M Lauer , Christophe Massard , Kelly Bennett , Shodeinde Coker , Ulrike Tontsch-Grunt , Sida Liao , Catherine J Wu , Kornelia Polyak , Sarina A Piha-Paul , Geoffrey I Shapiro

Characterizing Evolutionary Dynamics Reveals Strategies to Exhaust the Spectrum of Subclonal Resistance in EGFR-Mutant Lung Cancer.

Cancer research

Avec: Nina Müller , Carina Lorenz , Jenny Ostendorp , Felix S Heisel , Ulrich P Friese , Maria Cartolano , Dennis Plenker , Hannah Tumbrink , Alena Heimsoeth , Philipp Baedeker , Jonathan Weiss , Sandra Ortiz-Cuaran , Reinhard Büttner , Martin Peifer , Roman K Thomas , Johannes Berg , Johannes Brägelmann

Sorafenib and everolimus in patients with advanced solid tumors and KRAS-mutated NSCLC: A phase I trial with early pharmacodynamic FDG-PET assessment.

Cancer medicine

Avec: Lucia Nogova , Christian Mattonet , Matthias Scheffler , Max Taubert , Masyar Gardizi , Sebastian Michels , Rieke N Fischer , Meike Limburg , Diana S Y Abdulla , Thorsten Persigehl , Carsten Kobe , Sabine Merkelbach-Bruse , Jeremy Franklin , Heiko Backes , Roland Schnell , Dirk Behringer , Britta Kaminsky , Martina Eichstaedt , Christoph Stelzer , Martina Kinzig , Fritz Sörgel , Yingying Tian , Lisa Junge , Ahmed A Suleiman , Sebastian Frechen , Dennis Rokitta , Dongsheng Ouyang , Uwe Fuhr , Reinhard Buettner , Jürgen Wolf

CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization.

Molecular cancer therapeutics

Avec: Lisa Werr , Dennis Plenker , Marcel A Dammert , Carina Lorenz , Johannes Brägelmann , Hannah L Tumbrink , Sebastian Klein , Anna Schmitt , Reinhard Büttner , Thorsten Persigehl , Kevan M Shokat , F Thomas Wunderlich , Alison M Schram , Martin Peifer , H Christian Reinhardt , Roman K Thomas

Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes.

Nature communications

Avec: Christina M Bebber , Emily S Thomas , Jenny Stroh , Zhiyi Chen , Ariadne Androulidaki , Anna Schmitt , Michaela N Höhne , Lukas Stüker , Cleidson de Pádua Alves , Armin Khonsari , Marcel A Dammert , Fatma Parmaksiz , Hannah L Tumbrink , Filippo Beleggia , Jan Riemer , Julie George , Susanne Brodesser , Roman K Thomas , H Christian Reinhardt , Silvia von Karstedt

CDK9 inhibition as an effective therapy for small cell lung cancer.

Cell death & disease

Avec: L Valdez Capuccino , T Kleitke , B Szokol , L Svajda , F Martin , F Bonechi , M Krekó , S Azami , A Montinaro , Y Wang , V Nikolov , L Kaiser , D Bonasera , J Saggau , T Scholz , A Schmitt , F Beleggia , H C Reinhardt , J George , G Liccardi , H Walczak , J Tóvári , J Brägelmann , J Montero , M L Sos , L Őrfi , N Peltzer

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.

Nature communications

Avec: Marcel A Dammert , Johannes Brägelmann , Rachelle R Olsen , Stefanie Böhm , Niloufar Monhasery , Christopher P Whitney , Milind D Chalishazar , Hannah L Tumbrink , Matthew R Guthrie , Sebastian Klein , Abbie S Ireland , Jeremy Ryan , Anna Schmitt , Annika Marx , Luka Ozretić , Roberta Castiglione , Carina Lorenz , Ron D Jachimowicz , Elmar Wolf , Roman K Thomas , John T Poirier , Reinhard Büttner , Triparna Sen , Lauren A Byers , H Christian Reinhardt , Anthony Letai , Trudy G Oliver ,

Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer.

JCO precision oncology

Avec: Sebastian Michels , Carina Heydt , Bianca van Veggel , Barbara Deschler-Baier , Nuria Pardo , Kim Monkhorst , Vanessa Rüsseler , Jan Stratmann , Frank Griesinger , Susanne Steinhauser , Anna Kostenko , Joachim Diebold , Jana Fassunke , Rieke Fischer , Walburga Engel-Riedel , Oliver Gautschi , Eva Geissinger , Stefan Haneder , Michaela A Ihle , Hans-Georg Kopp , Adrianus J de Langen , Alex Martinez-Marti , Lucia Nogova , Thorsten Persigehl , Dennis Plenker , Michael Puesken , Ernst Rodermann , Andreas Rosenwald , Andreas H Scheel , Matthias Scheffler , Werner Spengler , Ruth Seggewiss-Bernhardt , Johannes Brägelmann , Martin Sebastian , Bart Vrugt , Martin Hellmich , Lukas C Heukamp , Enriqueta Felip , Sabine Merkelbach-Bruse , Egbert F Smit , Reinhard Büttner , Jürgen Wolf

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.

Nature communications

Avec: Johannes Brägelmann , Carina Lorenz , Sven Borchmann , Kazuya Nishii , Julia Wegner , Lydia Meder , Jenny Ostendorp , David F Ast , Alena Heimsoeth , Takamasa Nakasuka , Atsuko Hirabae , Sachi Okawa , Marcel A Dammert , Dennis Plenker , Sebastian Klein , Philipp Lohneis , Jianing Gu , Laura K Godfrey , Jan Forster , Marija Trajkovic-Arsic , Thomas Zillinger , Mareike Haarmann , Alexander Quaas , Stefanie Lennartz , Marcel Schmiel , Joshua D'Rozario , Emily S Thomas , Henry Li , Clemens A Schmitt , Julie George , Roman K Thomas , Silvia von Karstedt , Gunther Hartmann , Reinhard Büttner , Roland T Ullrich , Jens T Siveke , Kadoaki Ohashi , Martin Schlee ,

Réseau de co-auteurs

Reinhard Büttner 8 collaborations

Johannes Brägelmann 8 collaborations

Hannah L Tumbrink 7 collaborations

Roman K Thomas 7 collaborations

Alena Heimsoeth 5 collaborations

Lucia Nogova 5 collaborations

Sebastian Michels 5 collaborations

Sabine Merkelbach-Bruse 5 collaborations

Jürgen Wolf 5 collaborations

Matthias Scheffler 5 collaborations

Carina Lorenz 5 collaborations

Jana Fassunke 4 collaborations

Thorsten Persigehl 4 collaborations

Martin Peifer 4 collaborations

Dennis Plenker 4 collaborations

Marcel A Dammert 4 collaborations

Julie George 3 collaborations

Carsten Kobe 3 collaborations

Rieke Fischer 3 collaborations

Andreas H Scheel 3 collaborations

Carina Heydt 3 collaborations

Michaela A Ihle 3 collaborations

Sebastian Klein 3 collaborations

Anna Schmitt 3 collaborations

H Christian Reinhardt 3 collaborations

John T Poirier 2 collaborations

Lauren A Byers 2 collaborations

Trudy G Oliver 2 collaborations

Diana Schaufler 2 collaborations

David F Ast 2 collaborations

Nima Abedpour 2 collaborations

Inga Spille 2 collaborations

Stefanie Lennartz 2 collaborations

Theresa Westphal 2 collaborations

Sophia Koleczko 2 collaborations

Jan-Phillip Weber 2 collaborations

Oliver Gautschi 2 collaborations

Richard Riedel 2 collaborations

Rieke N Fischer 2 collaborations

Anna Eisert 2 collaborations

Janna Siemanowski 2 collaborations

Roberta Castiglione 2 collaborations

Diana S Y Abdulla 2 collaborations

Britta Kaminsky 2 collaborations

Martin Hellmich 2 collaborations

Lisa Werr 2 collaborations

Fatma Parmaksiz 2 collaborations

Jenny Ostendorp 2 collaborations

Emily S Thomas 2 collaborations

Silvia von Karstedt 2 collaborations

Taofeek K Owonikoko 1 collaboration

Anton Berns 1 collaboration

Elisabeth Brambilla 1 collaboration

David Carbone 1 collaboration

Huanhuan J Chen 1 collaboration

Camilla L Christensen 1 collaboration

Caroline Dive 1 collaboration

Anna F Farago 1 collaboration

Ramaswamy Govindan 1 collaboration

Christine Hann 1 collaboration

Matthew D Hellmann 1 collaboration

Leora Horn 1 collaboration

Jane E Johnson 1 collaboration

Young S Ju 1 collaboration

Sumin Kang 1 collaboration

Mark Krasnow 1 collaboration

James Lee 1 collaboration

Se-Hoon Lee 1 collaboration

Jonathan Lehman 1 collaboration

Benjamin Lok 1 collaboration

Christine Lovly 1 collaboration

David MacPherson 1 collaboration

David McFadden 1 collaboration

John Minna 1 collaboration

Matthew Oser 1 collaboration

Keunchil Park 1 collaboration

Kwon-Sik Park 1 collaboration

Yves Pommier 1 collaboration

Vito Quaranta 1 collaboration

Neal Ready 1 collaboration

Julien Sage 1 collaboration

Giorgio Scagliotti 1 collaboration

Kate D Sutherland 1 collaboration

William D Travis 1 collaboration

Christopher R Vakoc 1 collaboration

Sarah J Wait 1 collaboration

Ignacio Wistuba 1 collaboration

Kwok Kin Wong 1 collaboration

Hua Zhang 1 collaboration

Jillian Daigneault 1 collaboration

Jacinta Wiens 1 collaboration

Charles M Rudin 1 collaboration

Lukas Maas 1 collaboration

Ayla E Schwäbe 1 collaboration

Mihaela Aldea 1 collaboration

Benjamin Besse 1 collaboration

David Planchard 1 collaboration

Janine Altmüller 1 collaboration

Laura Mezquita 1 collaboration

Lena Hieggelke 1 collaboration

Svenja Wagener-Ryczek 1 collaboration

Roberto Pappesch 1 collaboration

Jan Rehker 1 collaboration

Jessica Jürgens 1 collaboration

Erich Stoelben 1 collaboration

Anne Bunck 1 collaboration

Rebecca Hein 1 collaboration

Anna Kron 1 collaboration

Frank Ueckeroth 1 collaboration

Merle Schüller 1 collaboration

Helen Pasternack 1 collaboration

Monika Serke 1 collaboration

Wolfgang Schulte 1 collaboration

Ulrich Gerigk 1 collaboration

Yon-Dschun Ko 1 collaboration

Karl-Otto Kambartel 1 collaboration

Joachim Lorenz 1 collaboration

Imke Sauerland 1 collaboration

Winfried Randerath 1 collaboration

Lars Hagmeyer 1 collaboration

Christian Grohé 1 collaboration

Rieke Frank 1 collaboration

Leonie Gogl 1 collaboration

Carsten Schaepers 1 collaboration

Alessandra Holzem 1 collaboration

Jonas Lategahn 1 collaboration

Carsten Schultz-Fademrecht 1 collaboration

Janina Niggenaber 1 collaboration

Marina Keul 1 collaboration

Matthias Baumann 1 collaboration

Sascha Menninger 1 collaboration

Eldar Zent 1 collaboration

Ina Landel 1 collaboration

Jörn Weisner 1 collaboration

Kirujan Jeyakumar 1 collaboration

Leonie Heyden 1 collaboration

Nicole Russ 1 collaboration

Fabienne Müller 1 collaboration

Tobias Grabe 1 collaboration

Matthias P Müller 1 collaboration

Johannes M Heuckmann 1 collaboration

Bert M Klebl 1 collaboration

Peter Nussbaumer 1 collaboration

Daniel Rauh 1 collaboration

Christopher A French 1 collaboration

Michael L Cheng 1 collaboration

Glenn J Hanna 1 collaboration

Steven G DuBois 1 collaboration

Nicole G Chau 1 collaboration

Christine L Hann 1 collaboration

Simone Storck 1 collaboration

Ravi Salgia 1 collaboration

Matteo Trucco 1 collaboration

Jennifer Tseng 1 collaboration

Anastasios Stathis 1 collaboration

Richard Piekarz 1 collaboration

Ulrich M Lauer 1 collaboration

Christophe Massard 1 collaboration

Kelly Bennett 1 collaboration

Shodeinde Coker 1 collaboration

Ulrike Tontsch-Grunt 1 collaboration

Sida Liao 1 collaboration

Catherine J Wu 1 collaboration

Kornelia Polyak 1 collaboration

Sarina A Piha-Paul 1 collaboration

Geoffrey I Shapiro 1 collaboration

Nina Müller 1 collaboration

Felix S Heisel 1 collaboration

Ulrich P Friese 1 collaboration

Maria Cartolano 1 collaboration

Hannah Tumbrink 1 collaboration

Philipp Baedeker 1 collaboration

Jonathan Weiss 1 collaboration

Sandra Ortiz-Cuaran 1 collaboration

Johannes Berg 1 collaboration

Christian Mattonet 1 collaboration

Max Taubert 1 collaboration

Masyar Gardizi 1 collaboration

Meike Limburg 1 collaboration

Jeremy Franklin 1 collaboration

Heiko Backes 1 collaboration

Roland Schnell 1 collaboration

Dirk Behringer 1 collaboration

Martina Eichstaedt 1 collaboration

Christoph Stelzer 1 collaboration

Martina Kinzig 1 collaboration

Fritz Sörgel 1 collaboration

Yingying Tian 1 collaboration

Lisa Junge 1 collaboration

Ahmed A Suleiman 1 collaboration

Sebastian Frechen 1 collaboration

Dennis Rokitta 1 collaboration

Dongsheng Ouyang 1 collaboration

Uwe Fuhr 1 collaboration

Reinhard Buettner 1 collaboration

Kevan M Shokat 1 collaboration

F Thomas Wunderlich 1 collaboration

Alison M Schram 1 collaboration

Christina M Bebber 1 collaboration

Jenny Stroh 1 collaboration

Zhiyi Chen 1 collaboration

Ariadne Androulidaki 1 collaboration

Michaela N Höhne 1 collaboration

Lukas Stüker 1 collaboration

Cleidson de Pádua Alves 1 collaboration

Armin Khonsari 1 collaboration

Filippo Beleggia 1 collaboration

Jan Riemer 1 collaboration

Susanne Brodesser 1 collaboration

L Valdez Capuccino 1 collaboration

T Kleitke 1 collaboration

B Szokol 1 collaboration

L Svajda 1 collaboration

F Martin 1 collaboration

F Bonechi 1 collaboration

M Krekó 1 collaboration

S Azami 1 collaboration

A Montinaro 1 collaboration

Y Wang 1 collaboration

V Nikolov 1 collaboration

L Kaiser 1 collaboration

D Bonasera 1 collaboration

J Saggau 1 collaboration

T Scholz 1 collaboration

A Schmitt 1 collaboration

F Beleggia 1 collaboration

H C Reinhardt 1 collaboration

J George 1 collaboration

G Liccardi 1 collaboration

H Walczak 1 collaboration

J Tóvári 1 collaboration

J Brägelmann 1 collaboration

J Montero 1 collaboration

M L Sos 1 collaboration

L Őrfi 1 collaboration

N Peltzer 1 collaboration

Rachelle R Olsen 1 collaboration

Stefanie Böhm 1 collaboration

Niloufar Monhasery 1 collaboration

Christopher P Whitney 1 collaboration

Milind D Chalishazar 1 collaboration

Matthew R Guthrie 1 collaboration

Abbie S Ireland 1 collaboration

Jeremy Ryan 1 collaboration

Annika Marx 1 collaboration

Luka Ozretić 1 collaboration

Ron D Jachimowicz 1 collaboration

Elmar Wolf 1 collaboration

Triparna Sen 1 collaboration

Anthony Letai 1 collaboration

Bianca van Veggel 1 collaboration

Barbara Deschler-Baier 1 collaboration

Nuria Pardo 1 collaboration

Kim Monkhorst 1 collaboration

Vanessa Rüsseler 1 collaboration

Jan Stratmann 1 collaboration

Frank Griesinger 1 collaboration

Susanne Steinhauser 1 collaboration

Anna Kostenko 1 collaboration

Joachim Diebold 1 collaboration

Walburga Engel-Riedel 1 collaboration

Eva Geissinger 1 collaboration

Stefan Haneder 1 collaboration

Hans-Georg Kopp 1 collaboration

Adrianus J de Langen 1 collaboration

Alex Martinez-Marti 1 collaboration

Michael Puesken 1 collaboration

Ernst Rodermann 1 collaboration

Andreas Rosenwald 1 collaboration

Werner Spengler 1 collaboration

Ruth Seggewiss-Bernhardt 1 collaboration

Martin Sebastian 1 collaboration

Bart Vrugt 1 collaboration

Lukas C Heukamp 1 collaboration

Enriqueta Felip 1 collaboration

Egbert F Smit 1 collaboration

Sven Borchmann 1 collaboration

Kazuya Nishii 1 collaboration

Julia Wegner 1 collaboration

Lydia Meder 1 collaboration

Takamasa Nakasuka 1 collaboration

Atsuko Hirabae 1 collaboration

Sachi Okawa 1 collaboration

Philipp Lohneis 1 collaboration

Jianing Gu 1 collaboration

Laura K Godfrey 1 collaboration

Jan Forster 1 collaboration

Marija Trajkovic-Arsic 1 collaboration

Thomas Zillinger 1 collaboration

Mareike Haarmann 1 collaboration

Alexander Quaas 1 collaboration

Marcel Schmiel 1 collaboration

Joshua D'Rozario 1 collaboration

Henry Li 1 collaboration

Clemens A Schmitt 1 collaboration

Gunther Hartmann 1 collaboration

Roland T Ullrich 1 collaboration

Jens T Siveke 1 collaboration

Kadoaki Ohashi 1 collaboration

Martin Schlee 1 collaboration