José V Castell

Affiliations

Hepatología Experimental, Health Research Institute La Fe, Valencia, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Departamento de Bioquímica y Biología Molecular, Universidad de Valencia, Valencia, Spain.
Unidad Analítica, Health Research Institute La Fe, Valencia, Spain.

Publications (18)

Monitoring of system conditioning after blank injections in untargeted UPLC-MS metabolomic analysis.

Scientific reports

Avec: Teresa Martínez-Sena , Giovanna Luongo , Daniel Sanjuan-Herráez , Máximo Vento , Guillermo Quintás , Julia Kuligowski

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.

Archives of toxicology

Avec: Wiebke Albrecht , Franziska Kappenberg , Tim Brecklinghaus , Regina Stoeber , Rosemarie Marchan , Mian Zhang , Kristina Ebbert , Hendrik Kirschner , Marianna Grinberg , Marcel Leist , Wolfgang Moritz , Cristina Cadenas , Ahmed Ghallab , Jörg Reinders , Nachiket Vartak , Christoph van Thriel , Klaus Golka , Laia Tolosa , Georg Damm , Daniel Seehofer , Alfonso Lampen , Albert Braeuning , Thorsten Buhrke , Anne-Cathrin Behr , Axel Oberemm , Xiaolong Gu , Naim Kittana , Bob van de Water , Reinhard Kreiling , Susann Fayyaz , Leon van Aerts , Bård Smedsrød , Heidrun Ellinger-Ziegelbauer , Thomas Steger-Hartmann , Ursula Gundert-Remy , Anja Zeigerer , Anett Ullrich , Dieter Runge , Serene M L Lee , Tobias S Schiergens , Lars Kuepfer , Alejandro Aguayo-Orozco , Agapios Sachinidis , Karolina Edlund , Iain Gardner , Jörg Rahnenführer , Jan G Hengstler

A Novel MicroRNA Signature for Cholestatic Drugs in Human Hepatocytes and Its Translation into Novel Circulating Biomarkers for Drug-Induced Liver Injury Patients.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Mireia López-Riera , Isabel Conde , Ramiro Jover

Comparing Targeted vs. Untargeted MS

Metabolites

Avec: Isabel Ten-Doménech , Teresa Martínez-Sena , Marta Moreno-Torres , Juan Daniel Sanjuan-Herráez , Anna Parra-Llorca , Máximo Vento , Guillermo Quintás , Julia Kuligowski

Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways.

International journal of molecular sciences

Avec: Ernesto López-Pascual , Ivan Rienda , Judith Perez-Rojas , Anna Rapisarda , Guillem Garcia-Llorens , Ramiro Jover ,

Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector.

Stem cell research & therapy

Avec: Maria Ballester , Miguel Bolonio , Ramon Santamaria , Carmen Ribes-Koninckx , Roque Bort

Toward Rapid Screening of Liver Grafts at the Operating Room Using Mid-infrared Spectroscopy.

Analytical chemistry

Avec: David Pérez-Guaita , Marta Moreno-Torres , Ramiro Jover , Eugenia Pareja , Bernhard Lendl , Julia Kuligowski , Guillermo Quintás , Jose Vicente Castell

Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen.

Antioxidants (Basel, Switzerland)

Avec: Rubén Rodríguez-Agudo , Naroa Goikoetxea-Usandizaga , Marina Serrano-Maciá , Pablo Fernández-Tussy , David Fernández-Ramos , Sofía Lachiondo-Ortega , Irene González-Recio , Clàudia Gil-Pitarch , María Mercado-Gómez , Laura Morán , Maider Bizkarguenaga , Fernando Lopitz-Otsoa , Petar Petrov , Miren Bravo , Sebastiaan Martijn Van Liempd , Juan Manuel Falcon-Perez , Amaia Zabala-Letona , Arkaitz Carracedo , Jose Vicente Castell , Ramiro Jover , Luis Alfonso Martínez-Cruz , Teresa Cardoso Delgado , Francisco Javier Cubero , María Isabel Lucena , Raúl Jesús Andrade , Jon Mabe , Jorge Simón , María Luz Martínez-Chantar

The Potential Role of Metabolomics in Drug-Induced Liver Injury (DILI) Assessment.

Metabolites

Avec: Marta Moreno-Torres , Guillermo Quintás ,

Extracting consistent biological information from functional results of metabolomic pathway analysis using the Mantel's test.

Analytica chimica acta

Avec: Isabel Ten-Doménech , Marta Moreno-Torres , José Vicente Castell , Guillermo Quintás , Julia Kuligowski

Modeling a Novel Variant of Glycogenosis IXa Using a Clonal Inducible Reprogramming System to Generate "Diseased" Hepatocytes for Accurate Diagnosis.

Journal of personalized medicine

Avec: Guillem Garcia-Llorens , Sergi Lopez-Navarro , Teresa Jaijo , Jose V Castell , Roque Bort

Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat.

International journal of molecular sciences

Avec: Guillermo Quintás , Florian Caiment , Iván Rienda , Judith Pérez-Rojas , Eugenia Pareja , Ramiro Jover

Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved.

Archives of toxicology

Avec: Teresa Martínez-Sena , Erika Moro , Marta Moreno-Torres , Guillermo Quintás , Jan Hengstler ,

The assessment of the potential hepatotoxicity of new drugs by

Frontiers in pharmacology

Avec: Guillermo Quintás , Marta Moreno-Torres

Enhancing the accuracy of mid-infrared spectroscopy-based liver steatosis quantification using digital image analysis as a reference.

The Analyst

Avec: Iván Rienda , Isabel Ten-Doménech , Erika Moro , Marta Moreno-Torres , Judith Pérez-Rojas , Eugenia Pareja , Álvaro Pérez-Rubio , Ramón Trullenque , Ramiro Jover , Bernhard Lendl , David Pérez-Guaita , Julia Kuligowski , Jose V Castell , Guillermo Quintás

Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.

Alternatives to laboratory animals : ATLA

Avec: Michael G Diemar , Mathieu Vinken , Marc Teunis , Cyrille A M Krul , Francois Busquet , Julia Dominika Zajac , Helena Kandarova , Raffaella Corvi , Matteo Z Rossi , Anastasiia Kharina , Louise Stab Bryndum , Michael Santillo , Denise Bloch , Olena Kucheryavenko , Demosthenes Panagiotakos , Vera Rogiers , Manon Beekhuijzen , Arianna Giusti , Abdulkarim Najjar , Carol Courage , Torben Koenig , Susanne Kolle , Harrie Boonen , Stephane Dhalluin , Julie Boberg , Boris P Müller , Predrag Kukic , Merel Ritskes-Hoitinga , Elena Grasselli , Tamara Zietek , Gilly Stoddart , Harm J Heusinkveld , Jose V Castell , Emilio Benfenati , Huan Yang , Simón Perera , Alicia Paini , Nynke I Kramer , Thomas Hartung , Manoe Janssen , Ellen Fritsche , Danyel G J Jennen , Matteo Piumatti , James Rathman , Jörg Marusczyk , Lucia Milec , Erwin L Roggen

Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis.

International journal of molecular sciences

Avec: Marta Moreno-Torres , Guillermo Quintás , Teresa Martínez-Sena , Ramiro Jover ,

Uncovering the toxicity mechanisms of a series of carboxylic acids in liver cells through computational and experimental approaches.

Toxicology

Avec: Rita Ortega-Vallbona , Rebeca Méndez , Laia Tolosa , Sylvia E Escher , Rafael Gozalbes , Eva Serrano-Candelas

Réseau de co-auteurs

Guillermo Quintás 10 collaborations

Marta Moreno-Torres 8 collaborations

Ramiro Jover 7 collaborations

Julia Kuligowski 5 collaborations

Teresa Martínez-Sena 4 collaborations

Isabel Ten-Doménech 3 collaborations

Eugenia Pareja 3 collaborations

Jose V Castell 3 collaborations

Máximo Vento 2 collaborations

Laia Tolosa 2 collaborations

Guillem Garcia-Llorens 2 collaborations

Roque Bort 2 collaborations

David Pérez-Guaita 2 collaborations

Bernhard Lendl 2 collaborations

Jose Vicente Castell 2 collaborations

Iván Rienda 2 collaborations

Judith Pérez-Rojas 2 collaborations

Erika Moro 2 collaborations

Giovanna Luongo 1 collaboration

Daniel Sanjuan-Herráez 1 collaboration

Wiebke Albrecht 1 collaboration

Franziska Kappenberg 1 collaboration

Tim Brecklinghaus 1 collaboration

Regina Stoeber 1 collaboration

Rosemarie Marchan 1 collaboration

Mian Zhang 1 collaboration

Kristina Ebbert 1 collaboration

Hendrik Kirschner 1 collaboration

Marianna Grinberg 1 collaboration

Marcel Leist 1 collaboration

Wolfgang Moritz 1 collaboration

Cristina Cadenas 1 collaboration

Ahmed Ghallab 1 collaboration

Jörg Reinders 1 collaboration

Nachiket Vartak 1 collaboration

Christoph van Thriel 1 collaboration

Klaus Golka 1 collaboration

Georg Damm 1 collaboration

Daniel Seehofer 1 collaboration

Alfonso Lampen 1 collaboration

Albert Braeuning 1 collaboration

Thorsten Buhrke 1 collaboration

Anne-Cathrin Behr 1 collaboration

Axel Oberemm 1 collaboration

Xiaolong Gu 1 collaboration

Naim Kittana 1 collaboration

Bob van de Water 1 collaboration

Reinhard Kreiling 1 collaboration

Susann Fayyaz 1 collaboration

Leon van Aerts 1 collaboration

Bård Smedsrød 1 collaboration

Heidrun Ellinger-Ziegelbauer 1 collaboration

Thomas Steger-Hartmann 1 collaboration

Ursula Gundert-Remy 1 collaboration

Anja Zeigerer 1 collaboration

Anett Ullrich 1 collaboration

Dieter Runge 1 collaboration

Serene M L Lee 1 collaboration

Tobias S Schiergens 1 collaboration

Lars Kuepfer 1 collaboration

Alejandro Aguayo-Orozco 1 collaboration

Agapios Sachinidis 1 collaboration

Karolina Edlund 1 collaboration

Iain Gardner 1 collaboration

Jörg Rahnenführer 1 collaboration

Jan G Hengstler 1 collaboration

Mireia López-Riera 1 collaboration

Isabel Conde 1 collaboration

Juan Daniel Sanjuan-Herráez 1 collaboration

Anna Parra-Llorca 1 collaboration

Ernesto López-Pascual 1 collaboration

Ivan Rienda 1 collaboration

Judith Perez-Rojas 1 collaboration

Anna Rapisarda 1 collaboration

Maria Ballester 1 collaboration

Miguel Bolonio 1 collaboration

Ramon Santamaria 1 collaboration

Carmen Ribes-Koninckx 1 collaboration

Rubén Rodríguez-Agudo 1 collaboration

Naroa Goikoetxea-Usandizaga 1 collaboration

Marina Serrano-Maciá 1 collaboration

Pablo Fernández-Tussy 1 collaboration

David Fernández-Ramos 1 collaboration

Sofía Lachiondo-Ortega 1 collaboration

Irene González-Recio 1 collaboration

Clàudia Gil-Pitarch 1 collaboration

María Mercado-Gómez 1 collaboration

Laura Morán 1 collaboration

Maider Bizkarguenaga 1 collaboration

Fernando Lopitz-Otsoa 1 collaboration

Petar Petrov 1 collaboration

Miren Bravo 1 collaboration

Sebastiaan Martijn Van Liempd 1 collaboration

Juan Manuel Falcon-Perez 1 collaboration

Amaia Zabala-Letona 1 collaboration

Arkaitz Carracedo 1 collaboration

Luis Alfonso Martínez-Cruz 1 collaboration

Teresa Cardoso Delgado 1 collaboration

Francisco Javier Cubero 1 collaboration

María Isabel Lucena 1 collaboration

Raúl Jesús Andrade 1 collaboration

Jon Mabe 1 collaboration

Jorge Simón 1 collaboration

María Luz Martínez-Chantar 1 collaboration

José Vicente Castell 1 collaboration

Sergi Lopez-Navarro 1 collaboration

Teresa Jaijo 1 collaboration

Florian Caiment 1 collaboration

Jan Hengstler 1 collaboration

Álvaro Pérez-Rubio 1 collaboration

Ramón Trullenque 1 collaboration

Michael G Diemar 1 collaboration

Mathieu Vinken 1 collaboration

Marc Teunis 1 collaboration

Cyrille A M Krul 1 collaboration

Francois Busquet 1 collaboration

Julia Dominika Zajac 1 collaboration

Helena Kandarova 1 collaboration

Raffaella Corvi 1 collaboration

Matteo Z Rossi 1 collaboration

Anastasiia Kharina 1 collaboration

Louise Stab Bryndum 1 collaboration

Michael Santillo 1 collaboration

Denise Bloch 1 collaboration

Olena Kucheryavenko 1 collaboration

Demosthenes Panagiotakos 1 collaboration

Vera Rogiers 1 collaboration

Manon Beekhuijzen 1 collaboration

Arianna Giusti 1 collaboration

Abdulkarim Najjar 1 collaboration

Carol Courage 1 collaboration

Torben Koenig 1 collaboration

Susanne Kolle 1 collaboration

Harrie Boonen 1 collaboration

Stephane Dhalluin 1 collaboration

Julie Boberg 1 collaboration

Boris P Müller 1 collaboration

Predrag Kukic 1 collaboration

Merel Ritskes-Hoitinga 1 collaboration

Elena Grasselli 1 collaboration

Tamara Zietek 1 collaboration

Gilly Stoddart 1 collaboration

Harm J Heusinkveld 1 collaboration

Emilio Benfenati 1 collaboration

Huan Yang 1 collaboration

Simón Perera 1 collaboration

Alicia Paini 1 collaboration

Nynke I Kramer 1 collaboration

Thomas Hartung 1 collaboration

Manoe Janssen 1 collaboration

Ellen Fritsche 1 collaboration

Danyel G J Jennen 1 collaboration

Matteo Piumatti 1 collaboration

James Rathman 1 collaboration

Jörg Marusczyk 1 collaboration

Lucia Milec 1 collaboration

Erwin L Roggen 1 collaboration

Rita Ortega-Vallbona 1 collaboration

Rebeca Méndez 1 collaboration

Sylvia E Escher 1 collaboration

Rafael Gozalbes 1 collaboration

Eva Serrano-Candelas 1 collaboration