Harm J Heusinkveld

Affiliations

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

Publications (21)

An efficient neuron-astrocyte differentiation protocol from human embryonic stem cell-derived neural progenitors to assess chemical-induced developmental neurotoxicity.

Reproductive toxicology (Elmsford, N.Y.)

Avec: Victoria C de Leeuw , Conny T M van Oostrom , Remco H S Westerink , Aldert H Piersma , Harm J Heusinkveld , Ellen V S Hessel

Exploring Neurobehaviour in Zebrafish Embryos as a Screening Model for Addictiveness of Substances.

Toxics

Avec: Anne Havermans , Edwin P Zwart , Hans W J M Cremers , Maarten D M van Schijndel , Romy S Constant , Maja Mešković , Laura X Worutowicz , Jeroen L A Pennings , Reinskje Talhout , Leo T M van der Ven , Harm J Heusinkveld

The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish.

Toxicology and applied pharmacology

Avec: Leo T M van der Ven , Willem G Schoonen , Renate M Groot , Fatima den Ouden , Harm J Heusinkveld , Edwin P Zwart , Hennie M Hodemaekers , Emiel Rorije , Joop de Knecht

Towards improved screening of toxins for Parkinson's risk.

NPJ Parkinson's disease

Avec: Ling Shan , Harm J Heusinkveld , Kimberly C Paul , Samantha Hughes , Sirwan K L Darweesh , Bastiaan R Bloem , Judith R Homberg

Effects of subchronic dietary exposure to the engineered nanomaterials SiO

Particle and fibre toxicology

Avec: Adriana Sofranko , Tina Wahle , Julia Kolling , Harm J Heusinkveld , Burkhard Stahlmecke , Martin Rosenbruch , Catrin Albrecht , Roel P F Schins

Dose addition in mixtures of compounds with dissimilar endocrine modes of action in in vitro receptor activation assays and the zebrafish sexual development test.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Avec: Toine Fh Bovee , Harm J Heusinkveld , Sophie Dodd , Ad Peijnenburg , Deborah Rijkers , Marco Blokland , R Corinne Sprong , Amélie Crépet , Antsje Nolles , Edwin P Zwart , Eric R Gremmer , Leo Tm van der Ven

Organophosphate insecticides disturb neuronal network development and function via non-AChE mediated mechanisms.

Neurotoxicology

Avec: Lennart V J van Melis , Harm J Heusinkveld , Celine Langendoen , Anouk Peters , Remco H S Westerink

New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens-a PARC project.

Frontiers in toxicology

Avec: Marc Audebert , Ann-Sophie Assmann , Amaya Azqueta , Pavel Babica , Emilio Benfenati , Sylvie Bortoli , Peter Bouwman , Albert Braeuning , Tanja Burgdorf , Xavier Coumoul , Kloé Debizet , Maria Dusinska , Norman Ertych , Jörg Fahrer , Verena Fetz , Ludovic Le Hégarat , Adela López de Cerain , Harm J Heusinkveld , Kevin Hogeveen , Miriam N Jacobs , Mirjam Luijten , Giuseppa Raitano , Cynthia Recoules , Elise Rundén-Pran , Mariam Saleh , Iva Sovadinová , Martina Stampar , Lea Thibol , Céline Tomkiewicz , Ariane Vettorazzi , Bob Van de Water , Naouale El Yamani , Bojana Zegura , Michael Oelgeschläger

New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project.

Frontiers in toxicology

Avec: Tamara Tal , Oddvar Myhre , Ellen Fritsche , Joëlle Rüegg , Kai Craenen , Kiara Aiello-Holden , Caroline Agrillo , Patrick J Babin , Beate I Escher , Hubert Dirven , Kati Hellsten , Kristine Dolva , Ellen Hessel , Harm J Heusinkveld , Yavor Hadzhiev , Selma Hurem , Karolina Jagiello , Beata Judzinska , Nils Klüver , Anja Knoll-Gellida , Britta A Kühne , Marcel Leist , Malene Lislien , Jan L Lyche , Ferenc Müller , John K Colbourne , Winfried Neuhaus , Giorgia Pallocca , Bettina Seeger , Ilka Scharkin , Stefan Scholz , Ola Spjuth , Monica Torres-Ruiz , Kristina Bartmann

The zebrafish embryo as a model for chemically-induced steatosis: a case study with three pesticides.

Toxicology

Avec: Harm J Heusinkveld , Edwin Zwart , Angela de Haan , Albert Braeuning , Jimmy Alarcan , Leo T M van der Ven

An ontology for developmental processes and toxicities of neural tube closure.

Reproductive toxicology (Elmsford, N.Y.)

Avec: Harm J Heusinkveld , Yvonne C M Staal , Nancy C Baker , George Daston , Thomas B Knudsen , Aldert Piersma

Acute, sub-chronic and chronic exposures to TiO

Neurotoxicology

Avec: Lora-Sophie Gerber , Harm J Heusinkveld , Celine Langendoen , Burkhard Stahlmecke , Roel Pf Schins , Remco Hs Westerink

An adverse outcome pathway for chemical-induced Parkinson's disease: Calcium is key.

Neurotoxicology

Avec: Julia J Meerman , Juliette Legler , Aldert H Piersma , Remco H S Westerink , Harm J Heusinkveld

Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.

Alternatives to laboratory animals : ATLA

Avec: Michael G Diemar , Mathieu Vinken , Marc Teunis , Cyrille A M Krul , Francois Busquet , Julia Dominika Zajac , Helena Kandarova , Raffaella Corvi , Matteo Z Rossi , Anastasiia Kharina , Louise Stab Bryndum , Michael Santillo , Denise Bloch , Olena Kucheryavenko , Demosthenes Panagiotakos , Vera Rogiers , Manon Beekhuijzen , Arianna Giusti , Abdulkarim Najjar , Carol Courage , Torben Koenig , Susanne Kolle , Harrie Boonen , Stephane Dhalluin , Julie Boberg , Boris P Müller , Predrag Kukic , Merel Ritskes-Hoitinga , Elena Grasselli , Tamara Zietek , Gilly Stoddart , Harm J Heusinkveld , Jose V Castell , Emilio Benfenati , Huan Yang , Simón Perera , Alicia Paini , Nynke I Kramer , Thomas Hartung , Manoe Janssen , Ellen Fritsche , Danyel G J Jennen , Matteo Piumatti , James Rathman , Jörg Marusczyk , Lucia Milec , Erwin L Roggen

Distinguishing mode of action of compounds inducing craniofacial malformations in zebrafish embryos to support dose-response modeling in combined exposures.

Reproductive toxicology (Elmsford, N.Y.)

Avec: Harm J Heusinkveld , Willem G Schoonen , Hennie M Hodemaekers , Ananditya Nugraha , Jan-Jaap Sirks , Vivianne Veenma , Carina Sujan , Jeroen L A Pennings , Paul F Wackers , Luca Palazzolo , Ivano Eberini , Emiel Rorije , Leo T M van der Ven

Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer's and vascular disease.

Neurochemistry international

Avec: Tina Wahle , Adriana Sofranko , Susan Dekkers , Mark R Miller , Harm J Heusinkveld , Catrin Albrecht , Flemming R Cassee , Roel P F Schins

Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies.

Neurotoxicology

Avec: Adriana Sofranko , Tina Wahle , Harm J Heusinkveld , Burkhard Stahlmecke , Michail Dronov , Dirk Pijnenburg , Riet Hilhorst , Karsten Lamann , Catrin Albrecht , Roel P F Schins

Relevance of

Chemical research in toxicology

Avec: Mirjam Luijten , Paul F K Wackers , Emiel Rorije , Jeroen L A Pennings , Harm J Heusinkveld

Dose Addition in the Induction of Craniofacial Malformations in Zebrafish Embryos Exposed to a Complex Mixture of Food-Relevant Chemicals with Dissimilar Modes of Action.

Environmental health perspectives

Avec: Leo T M Van Der Ven , Paul Van Ommeren , Edwin P Zwart , Eric R Gremmer , Hennie M Hodemaekers , Harm J Heusinkveld , Jacob D van Klaveren , Emiel Rorije

Developmental Neurotoxicity of Environmentally Relevant Pharmaceuticals and Mixtures Thereof in a Zebrafish Embryo Behavioural Test.

International journal of environmental research and public health

Avec: Alessandro Atzei , Ingrid Jense , Edwin P Zwart , Jessica Legradi , Bastiaan J Venhuis , Leo T M van der Ven , Harm J Heusinkveld , Ellen V S Hessel

Prolonged Differentiation of Neuron-Astrocyte Co-Cultures Results in Emergence of Dopaminergic Neurons.

International journal of molecular sciences

Avec: Victoria C de Leeuw , Conny T M van Oostrom , Edwin P Zwart , Harm J Heusinkveld , Ellen V S Hessel

Réseau de co-auteurs

Edwin P Zwart 6 collaborations

Leo T M van der Ven 5 collaborations

Emiel Rorije 4 collaborations

Remco H S Westerink 3 collaborations

Ellen V S Hessel 3 collaborations

Jeroen L A Pennings 3 collaborations

Hennie M Hodemaekers 3 collaborations

Adriana Sofranko 3 collaborations

Tina Wahle 3 collaborations

Burkhard Stahlmecke 3 collaborations

Catrin Albrecht 3 collaborations

Roel P F Schins 3 collaborations

Victoria C de Leeuw 2 collaborations

Conny T M van Oostrom 2 collaborations

Aldert H Piersma 2 collaborations

Willem G Schoonen 2 collaborations

Eric R Gremmer 2 collaborations

Celine Langendoen 2 collaborations

Emilio Benfenati 2 collaborations

Albert Braeuning 2 collaborations

Mirjam Luijten 2 collaborations

Ellen Fritsche 2 collaborations

Anne Havermans 1 collaboration

Hans W J M Cremers 1 collaboration

Maarten D M van Schijndel 1 collaboration

Romy S Constant 1 collaboration

Maja Mešković 1 collaboration

Laura X Worutowicz 1 collaboration

Reinskje Talhout 1 collaboration

Renate M Groot 1 collaboration

Fatima den Ouden 1 collaboration

Joop de Knecht 1 collaboration

Ling Shan 1 collaboration

Kimberly C Paul 1 collaboration

Samantha Hughes 1 collaboration

Sirwan K L Darweesh 1 collaboration

Bastiaan R Bloem 1 collaboration

Judith R Homberg 1 collaboration

Julia Kolling 1 collaboration

Martin Rosenbruch 1 collaboration

Toine Fh Bovee 1 collaboration

Sophie Dodd 1 collaboration

Ad Peijnenburg 1 collaboration

Deborah Rijkers 1 collaboration

Marco Blokland 1 collaboration

R Corinne Sprong 1 collaboration

Amélie Crépet 1 collaboration

Antsje Nolles 1 collaboration

Leo Tm van der Ven 1 collaboration

Lennart V J van Melis 1 collaboration

Anouk Peters 1 collaboration

Marc Audebert 1 collaboration

Ann-Sophie Assmann 1 collaboration

Amaya Azqueta 1 collaboration

Pavel Babica 1 collaboration

Sylvie Bortoli 1 collaboration

Peter Bouwman 1 collaboration

Tanja Burgdorf 1 collaboration

Xavier Coumoul 1 collaboration

Kloé Debizet 1 collaboration

Maria Dusinska 1 collaboration

Norman Ertych 1 collaboration

Jörg Fahrer 1 collaboration

Verena Fetz 1 collaboration

Ludovic Le Hégarat 1 collaboration

Adela López de Cerain 1 collaboration

Kevin Hogeveen 1 collaboration

Miriam N Jacobs 1 collaboration

Giuseppa Raitano 1 collaboration

Cynthia Recoules 1 collaboration

Elise Rundén-Pran 1 collaboration

Mariam Saleh 1 collaboration

Iva Sovadinová 1 collaboration

Martina Stampar 1 collaboration

Lea Thibol 1 collaboration

Céline Tomkiewicz 1 collaboration

Ariane Vettorazzi 1 collaboration

Bob Van de Water 1 collaboration

Naouale El Yamani 1 collaboration

Bojana Zegura 1 collaboration

Michael Oelgeschläger 1 collaboration

Tamara Tal 1 collaboration

Oddvar Myhre 1 collaboration

Joëlle Rüegg 1 collaboration

Kai Craenen 1 collaboration

Kiara Aiello-Holden 1 collaboration

Caroline Agrillo 1 collaboration

Patrick J Babin 1 collaboration

Beate I Escher 1 collaboration

Hubert Dirven 1 collaboration

Kati Hellsten 1 collaboration

Kristine Dolva 1 collaboration

Ellen Hessel 1 collaboration

Yavor Hadzhiev 1 collaboration

Selma Hurem 1 collaboration

Karolina Jagiello 1 collaboration

Beata Judzinska 1 collaboration

Nils Klüver 1 collaboration

Anja Knoll-Gellida 1 collaboration

Britta A Kühne 1 collaboration

Marcel Leist 1 collaboration

Malene Lislien 1 collaboration

Jan L Lyche 1 collaboration

Ferenc Müller 1 collaboration

John K Colbourne 1 collaboration

Winfried Neuhaus 1 collaboration

Giorgia Pallocca 1 collaboration

Bettina Seeger 1 collaboration

Ilka Scharkin 1 collaboration

Stefan Scholz 1 collaboration

Ola Spjuth 1 collaboration

Monica Torres-Ruiz 1 collaboration

Kristina Bartmann 1 collaboration

Edwin Zwart 1 collaboration

Angela de Haan 1 collaboration

Jimmy Alarcan 1 collaboration

Yvonne C M Staal 1 collaboration

Nancy C Baker 1 collaboration

George Daston 1 collaboration

Thomas B Knudsen 1 collaboration

Aldert Piersma 1 collaboration

Lora-Sophie Gerber 1 collaboration

Roel Pf Schins 1 collaboration

Remco Hs Westerink 1 collaboration

Julia J Meerman 1 collaboration

Juliette Legler 1 collaboration

Michael G Diemar 1 collaboration

Mathieu Vinken 1 collaboration

Marc Teunis 1 collaboration

Cyrille A M Krul 1 collaboration

Francois Busquet 1 collaboration

Julia Dominika Zajac 1 collaboration

Helena Kandarova 1 collaboration

Raffaella Corvi 1 collaboration

Matteo Z Rossi 1 collaboration

Anastasiia Kharina 1 collaboration

Louise Stab Bryndum 1 collaboration

Michael Santillo 1 collaboration

Denise Bloch 1 collaboration

Olena Kucheryavenko 1 collaboration

Demosthenes Panagiotakos 1 collaboration

Vera Rogiers 1 collaboration

Manon Beekhuijzen 1 collaboration

Arianna Giusti 1 collaboration

Abdulkarim Najjar 1 collaboration

Carol Courage 1 collaboration

Torben Koenig 1 collaboration

Susanne Kolle 1 collaboration

Harrie Boonen 1 collaboration

Stephane Dhalluin 1 collaboration

Julie Boberg 1 collaboration

Boris P Müller 1 collaboration

Predrag Kukic 1 collaboration

Merel Ritskes-Hoitinga 1 collaboration

Elena Grasselli 1 collaboration

Tamara Zietek 1 collaboration

Gilly Stoddart 1 collaboration

Jose V Castell 1 collaboration

Huan Yang 1 collaboration

Simón Perera 1 collaboration

Alicia Paini 1 collaboration

Nynke I Kramer 1 collaboration

Thomas Hartung 1 collaboration

Manoe Janssen 1 collaboration

Danyel G J Jennen 1 collaboration

Matteo Piumatti 1 collaboration

James Rathman 1 collaboration

Jörg Marusczyk 1 collaboration

Lucia Milec 1 collaboration

Erwin L Roggen 1 collaboration

Ananditya Nugraha 1 collaboration

Jan-Jaap Sirks 1 collaboration

Vivianne Veenma 1 collaboration

Carina Sujan 1 collaboration

Paul F Wackers 1 collaboration

Luca Palazzolo 1 collaboration

Ivano Eberini 1 collaboration

Susan Dekkers 1 collaboration

Mark R Miller 1 collaboration

Flemming R Cassee 1 collaboration

Michail Dronov 1 collaboration

Dirk Pijnenburg 1 collaboration

Riet Hilhorst 1 collaboration

Karsten Lamann 1 collaboration

Paul F K Wackers 1 collaboration

Leo T M Van Der Ven 1 collaboration

Paul Van Ommeren 1 collaboration

Jacob D van Klaveren 1 collaboration

Alessandro Atzei 1 collaboration

Ingrid Jense 1 collaboration

Jessica Legradi 1 collaboration

Bastiaan J Venhuis 1 collaboration