John C Chaput

Affiliations
  • Departments of Pharmaceutical Sciences, Chemistry, Molecular Biology and Biochemistry, University of California, Irvine, CA, USA.

Publications (10)

Synthesis and polymerase recognition of a pyrrolocytidine TNA triphosphate.

Biopolymers
Avec: Hui Mei , Yajun Wang , Eric J Yik ,

RNA-Catalyzed Polymerization of Deoxyribose, Threose, and Arabinose Nucleic Acids.

ACS synthetic biology
Avec: David P Horning , Saikat Bala , Gerald F Joyce

Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities.

Journal of the American Chemical Society
Avec: Qingfeng Li , Victoria A Maola , Nicholas Chim , Javeena Hussain , Adriana Lozoya-Colinas ,

Redesigning the Genetic Polymers of Life.

Accounts of chemical research
Avec:

Reading and Writing Digital Information in TNA.

ACS synthetic biology
Avec: Kefan Yang , Cailen M McCloskey ,

Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.

Journal of the American Chemical Society
Avec: Shigeo Matsuda , Saikat Bala , Jen-Yu Liao , Dhrubajyoti Datta , Atsushi Mikami , Lauren Woods , Joel M Harp , Jason A Gilbert , Anna Bisbe , Rajar M Manoharan , MaryBeth Kim , Christopher S Theile , Dale C Guenther , Yongfeng Jiang , Saket Agarwal , Rajanikanth Maganti , Mark K Schlegel , Ivan Zlatev , Klaus Charisse , Kallanthottathil G Rajeev , Adam Castoreno , Martin Maier , Maja M Janas , Martin Egli , Muthiah Manoharan

Chemical evolution of an autonomous DNAzyme with allele-specific gene silencing activity.

Nature communications
Avec: Kim Nguyen , Turnee N Malik ,

Functionally Enhanced XNA Aptamers Discovered by Parallelized Library Screening.

Journal of the American Chemical Society
Avec: Adriana Lozoya-Colinas , Yutong Yu ,

Improved synthesis and polymerase recognition of 7-deaza-7-modified α-l-threofuranosyl guanosine analogs.

RSC advances
Avec: Bhawna Barpuzary , Sergey Negria ,

Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase.

Nucleic acids research
Avec: Lynnette N Jackson , Nicholas Chim , Changhua Shi ,

Réseau de co-auteurs

Saikat Bala 2 collaborations
Nicholas Chim 2 collaborations
Adriana Lozoya-Colinas 2 collaborations
Hui Mei 1 collaboration
Yajun Wang 1 collaboration
Eric J Yik 1 collaboration
David P Horning 1 collaboration
Gerald F Joyce 1 collaboration
Qingfeng Li 1 collaboration
Victoria A Maola 1 collaboration
Javeena Hussain 1 collaboration
Kefan Yang 1 collaboration
Cailen M McCloskey 1 collaboration
Shigeo Matsuda 1 collaboration
Jen-Yu Liao 1 collaboration
Dhrubajyoti Datta 1 collaboration
Atsushi Mikami 1 collaboration
Lauren Woods 1 collaboration
Joel M Harp 1 collaboration
Jason A Gilbert 1 collaboration
Anna Bisbe 1 collaboration
Rajar M Manoharan 1 collaboration
MaryBeth Kim 1 collaboration
Christopher S Theile 1 collaboration
Dale C Guenther 1 collaboration
Yongfeng Jiang 1 collaboration
Saket Agarwal 1 collaboration
Rajanikanth Maganti 1 collaboration
Mark K Schlegel 1 collaboration
Ivan Zlatev 1 collaboration
Klaus Charisse 1 collaboration
Kallanthottathil G Rajeev 1 collaboration
Adam Castoreno 1 collaboration
Martin Maier 1 collaboration
Maja M Janas 1 collaboration
Martin Egli 1 collaboration
Muthiah Manoharan 1 collaboration
Kim Nguyen 1 collaboration
Turnee N Malik 1 collaboration
Yutong Yu 1 collaboration
Bhawna Barpuzary 1 collaboration
Sergey Negria 1 collaboration
Lynnette N Jackson 1 collaboration
Changhua Shi 1 collaboration