Anna Bisbe

Affiliations

Alnylam Pharmaceuticals, 675 West Kendall, Cambridge, Massachusetts 02142, United States.

Publications (6)

Role of a "Magic" Methyl: 2'-Deoxy-2'-α-F-2'-β-

Journal of the American Chemical Society

Avec: Dale C Guenther , Shohei Mori , Shigeo Matsuda , Jason A Gilbert , Jennifer L S Willoughby , Sarah Hyde , Yongfeng Jiang , Saket Agarwal , Mimouna Madaoui , Maja M Janas , Klaus Charisse , Martin A Maier , Martin Egli , Muthiah Manoharan

Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo.

Nucleic acids research

Avec: Hartmut Jahns , Nate Taneja , Jennifer L S Willoughby , Masaaki Akabane-Nakata , Christopher R Brown , Tuyen Nguyen , Shigeo Matsuda , Matt Hettinger , Rajar M Manoharan , Kallanthottathil G Rajeev , Martin A Maier , Ivan Zlatev , Klaus Charisse , Martin Egli , Muthiah Manoharan

Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.

Journal of the American Chemical Society

Avec: Shigeo Matsuda , Saikat Bala , Jen-Yu Liao , Dhrubajyoti Datta , Atsushi Mikami , Lauren Woods , Joel M Harp , Jason A Gilbert , Rajar M Manoharan , MaryBeth Kim , Christopher S Theile , Dale C Guenther , Yongfeng Jiang , Saket Agarwal , Rajanikanth Maganti , Mark K Schlegel , Ivan Zlatev , Klaus Charisse , Kallanthottathil G Rajeev , Adam Castoreno , Martin Maier , Maja M Janas , Martin Egli , John C Chaput , Muthiah Manoharan

Metabolically Stable Anomeric Linkages Containing GalNAc-siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways.

Journal of medicinal chemistry

Avec: Pachamuthu Kandasamy , Shohei Mori , Shigeo Matsuda , Namrata Erande , Dhrubajyoti Datta , Jennifer L S Willoughby , Nate Taneja , Jonathan O'Shea , Rajar M Manoharan , Kristina Yucius , Tuyen Nguyen , Ramesh Indrakanti , Swati Gupta , Jason A Gilbert , Tim Racie , Amy Chan , Ju Liu , Renta Hutabarat , Jayaprakash K Nair , Klaus Charisse , Martin A Maier , Kallanthottathil G Rajeev , Martin Egli , Muthiah Manoharan

RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes.

Nature communications

Avec: Megha Subramanian , James McIninch , Ivan Zlatev , Mark K Schlegel , Charalambos Kaittanis , Tuyen Nguyen , Saket Agarwal , Timothy Racie , Martha Arbaiza Alvarado , Kelly Wassarman , Thomas S Collins , Tyler Chickering , Christopher R Brown , Karyn Schmidt , Adam B Castoreno , Svetlana Shulga-Morskaya , Elena Stamenova , Kira Buckowing , Daniel Berman , Joseph D Barry , Martin A Maier , Kevin Fitzgerald , Vasant Jadhav

Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing.

Nucleic acids research

Avec: Hartmut Jahns , Rohan Degaonkar , Peter Podbevsek , Swati Gupta , Krishna Aluri , John Szeto , Pawan Kumar , Sarah LeBlanc , Tim Racie , Christopher R Brown , Adam Castoreno , Dale C Guenther , Vasant Jadhav , Martin A Maier , Janez Plavec , Martin Egli , Muthiah Manoharan , Ivan Zlatev

Réseau de co-auteurs

Martin A Maier 5 collaborations

Martin Egli 5 collaborations

Muthiah Manoharan 5 collaborations

Shigeo Matsuda 4 collaborations

Klaus Charisse 4 collaborations

Ivan Zlatev 4 collaborations

Dale C Guenther 3 collaborations

Jason A Gilbert 3 collaborations

Jennifer L S Willoughby 3 collaborations

Saket Agarwal 3 collaborations

Christopher R Brown 3 collaborations

Tuyen Nguyen 3 collaborations

Rajar M Manoharan 3 collaborations

Kallanthottathil G Rajeev 3 collaborations

Shohei Mori 2 collaborations

Yongfeng Jiang 2 collaborations

Maja M Janas 2 collaborations

Hartmut Jahns 2 collaborations

Nate Taneja 2 collaborations

Dhrubajyoti Datta 2 collaborations

Mark K Schlegel 2 collaborations

Adam Castoreno 2 collaborations

Swati Gupta 2 collaborations

Tim Racie 2 collaborations

Vasant Jadhav 2 collaborations

Sarah Hyde 1 collaboration

Mimouna Madaoui 1 collaboration

Masaaki Akabane-Nakata 1 collaboration

Matt Hettinger 1 collaboration

Saikat Bala 1 collaboration

Jen-Yu Liao 1 collaboration

Atsushi Mikami 1 collaboration

Lauren Woods 1 collaboration

Joel M Harp 1 collaboration

MaryBeth Kim 1 collaboration

Christopher S Theile 1 collaboration

Rajanikanth Maganti 1 collaboration

Martin Maier 1 collaboration

John C Chaput 1 collaboration

Pachamuthu Kandasamy 1 collaboration

Namrata Erande 1 collaboration

Jonathan O'Shea 1 collaboration

Kristina Yucius 1 collaboration

Ramesh Indrakanti 1 collaboration

Amy Chan 1 collaboration

Ju Liu 1 collaboration

Renta Hutabarat 1 collaboration

Jayaprakash K Nair 1 collaboration

Megha Subramanian 1 collaboration

James McIninch 1 collaboration

Charalambos Kaittanis 1 collaboration

Timothy Racie 1 collaboration

Martha Arbaiza Alvarado 1 collaboration

Kelly Wassarman 1 collaboration

Thomas S Collins 1 collaboration

Tyler Chickering 1 collaboration

Karyn Schmidt 1 collaboration

Adam B Castoreno 1 collaboration

Svetlana Shulga-Morskaya 1 collaboration

Elena Stamenova 1 collaboration

Kira Buckowing 1 collaboration

Daniel Berman 1 collaboration

Joseph D Barry 1 collaboration

Kevin Fitzgerald 1 collaboration

Rohan Degaonkar 1 collaboration

Peter Podbevsek 1 collaboration

Krishna Aluri 1 collaboration

John Szeto 1 collaboration

Pawan Kumar 1 collaboration

Sarah LeBlanc 1 collaboration

Janez Plavec 1 collaboration