Jeffery A Engelman

Publications (6)

Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer.

Oncogene

Avec: Sana Raoof , Iain J Mulford , Heidie Frisco-Cabanos , Varuna Nangia , Daria Timonina , Emma Labrot , Nafeeza Hafeez , Samantha J Bilton , Yotam Drier , Fei Ji , Max Greenberg , August Williams , Krystina Kattermann , Leah Damon , Sosathya Sovath , Daniel P Rakiec , Joshua M Korn , David A Ruddy , Cyril H Benes , Peter S Hammerman , Zofia Piotrowska , Lecia V Sequist , Matthew J Niederst , Jordi Barretina , Jeffrey A Engelman , Aaron N Hata

SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.

Scientific reports

Avec: Ye Wang , Morvarid Mohseni , Angelo Grauel , Javier Estrada Diez , Wei Guan , Simon Liang , Jiyoung Elizabeth Choi , Minying Pu , Dongshu Chen , Tyler Laszewski , Stephanie Schwartz , Jane Gu , Leandra Mansur , Tyler Burks , Lauren Brodeur , Roberto Velazquez , Steve Kovats , Bhavesh Pant , Giri Buruzula , Emily Deng , Julie T Chen , Farid Sari-Sarraf , Christina Dornelas , Malini Varadarajan , Haiyan Yu , Chen Liu , Joanne Lim , Huai-Xiang Hao , Xiaomo Jiang , Anthony Malamas , Matthew J LaMarche , Felipe Correa Geyer , Margaret McLaughlin , Carlotta Costa , Joel Wagner , David Ruddy , Pushpa Jayaraman , Nathaniel D Kirkpatrick , Pu Zhang , Oleg Iartchouk , Kimberly Aardalen , Viviana Cremasco , Glenn Dranoff , Jeffrey A Engelman , Serena Silver , Hongyun Wang , William D Hastings , Silvia Goldoni

TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts.

Nature communications

Avec: Angelo L Grauel , Beverly Nguyen , David Ruddy , Tyler Laszewski , Stephanie Schwartz , Jonathan Chang , Julie Chen , Michelle Piquet , Marc Pelletier , Zheng Yan , Nathaniel D Kirkpatrick , Jincheng Wu , Antoine deWeck , Markus Riester , Matt Hims , Felipe Correa Geyer , Joel Wagner , Kenzie MacIsaac , James Deeds , Rohan Diwanji , Pushpa Jayaraman , Yenyen Yu , Quincey Simmons , Shaobu Weng , Alina Raza , Brian Minie , Mirek Dostalek , Pavitra Chikkegowda , Vera Ruda , Oleg Iartchouk , Naiyan Chen , Raphael Thierry , Joseph Zhou , Iulian Pruteanu-Malinici , Claire Fabre , Jeffrey A Engelman , Glenn Dranoff , Viviana Cremasco

Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity.

Cell reports

Avec: Lynnette Marcar , Kankana Bardhan , Liliana Gheorghiu , Patrick Dinkelborg , Heike Pfäffle , Qi Liu , Meng Wang , Zofia Piotrowska , Lecia V Sequist , Kerstin Borgmann , Jeffrey E Settleman , Jeffrey A Engelman , Aaron N Hata , Henning Willers

NOTCH1 Represses MCL-1 Levels in GSI-resistant T-ALL, Making them Susceptible to ABT-263.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Anahita Dastur , AHyun Choi , Carlotta Costa , Xunqin Yin , August Williams , Joseph McClanaghan , Max Greenberg , Justine Roderick , Neha U Patel , Jessica Boisvert , Ultan McDermott , Mathew J Garnett , Jorge Almenara , Steven Grant , Kathryn Rizzo , Jeffrey A Engelman , Michelle Kelliher , Anthony C Faber , Cyril H Benes

A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts.

Cancer research

Avec: Adam C Palmer , Deborah Plana , Hui Gao , Joshua M Korn , Guizhi Yang , John Green , Xiamei Zhang , Roberto Velazquez , Margaret E McLaughlin , David A Ruddy , Colleen Kowal , Julie Muszynski , Caroline Bullock , Stacy Rivera , Daniel P Rakiec , GiNell Elliott , Paul Fordjour , Ronald Meyer , Alice Loo , Esther Kurth , Jeffrey A Engelman , Hans Bitter , William R Sellers , Juliet A Williams , Peter K Sorger

Réseau de co-auteurs

Jeffrey A Engelman 6 collaborations

Max Greenberg 2 collaborations

August Williams 2 collaborations

Daniel P Rakiec 2 collaborations

Joshua M Korn 2 collaborations

David A Ruddy 2 collaborations

Cyril H Benes 2 collaborations

Zofia Piotrowska 2 collaborations

Lecia V Sequist 2 collaborations

Aaron N Hata 2 collaborations

Tyler Laszewski 2 collaborations

Stephanie Schwartz 2 collaborations

Roberto Velazquez 2 collaborations

Felipe Correa Geyer 2 collaborations

Carlotta Costa 2 collaborations

Joel Wagner 2 collaborations

David Ruddy 2 collaborations

Pushpa Jayaraman 2 collaborations

Nathaniel D Kirkpatrick 2 collaborations

Oleg Iartchouk 2 collaborations

Viviana Cremasco 2 collaborations

Glenn Dranoff 2 collaborations

Sana Raoof 1 collaboration

Iain J Mulford 1 collaboration

Heidie Frisco-Cabanos 1 collaboration

Varuna Nangia 1 collaboration

Daria Timonina 1 collaboration

Emma Labrot 1 collaboration

Nafeeza Hafeez 1 collaboration

Samantha J Bilton 1 collaboration

Yotam Drier 1 collaboration

Fei Ji 1 collaboration

Krystina Kattermann 1 collaboration

Leah Damon 1 collaboration

Sosathya Sovath 1 collaboration

Peter S Hammerman 1 collaboration

Matthew J Niederst 1 collaboration

Jordi Barretina 1 collaboration

Ye Wang 1 collaboration

Morvarid Mohseni 1 collaboration

Angelo Grauel 1 collaboration

Javier Estrada Diez 1 collaboration

Wei Guan 1 collaboration

Simon Liang 1 collaboration

Jiyoung Elizabeth Choi 1 collaboration

Minying Pu 1 collaboration

Dongshu Chen 1 collaboration

Jane Gu 1 collaboration

Leandra Mansur 1 collaboration

Tyler Burks 1 collaboration

Lauren Brodeur 1 collaboration

Steve Kovats 1 collaboration

Bhavesh Pant 1 collaboration

Giri Buruzula 1 collaboration

Emily Deng 1 collaboration

Julie T Chen 1 collaboration

Farid Sari-Sarraf 1 collaboration

Christina Dornelas 1 collaboration

Malini Varadarajan 1 collaboration

Haiyan Yu 1 collaboration

Chen Liu 1 collaboration

Joanne Lim 1 collaboration

Huai-Xiang Hao 1 collaboration

Xiaomo Jiang 1 collaboration

Anthony Malamas 1 collaboration

Matthew J LaMarche 1 collaboration

Margaret McLaughlin 1 collaboration

Pu Zhang 1 collaboration

Kimberly Aardalen 1 collaboration

Serena Silver 1 collaboration

Hongyun Wang 1 collaboration

William D Hastings 1 collaboration

Silvia Goldoni 1 collaboration

Angelo L Grauel 1 collaboration

Beverly Nguyen 1 collaboration

Jonathan Chang 1 collaboration

Julie Chen 1 collaboration

Michelle Piquet 1 collaboration

Marc Pelletier 1 collaboration

Zheng Yan 1 collaboration

Jincheng Wu 1 collaboration

Antoine deWeck 1 collaboration

Markus Riester 1 collaboration

Matt Hims 1 collaboration

Kenzie MacIsaac 1 collaboration

James Deeds 1 collaboration

Rohan Diwanji 1 collaboration

Yenyen Yu 1 collaboration

Quincey Simmons 1 collaboration

Shaobu Weng 1 collaboration

Alina Raza 1 collaboration

Brian Minie 1 collaboration

Mirek Dostalek 1 collaboration

Pavitra Chikkegowda 1 collaboration

Vera Ruda 1 collaboration

Naiyan Chen 1 collaboration

Raphael Thierry 1 collaboration

Joseph Zhou 1 collaboration

Iulian Pruteanu-Malinici 1 collaboration

Claire Fabre 1 collaboration

Lynnette Marcar 1 collaboration

Kankana Bardhan 1 collaboration

Liliana Gheorghiu 1 collaboration

Patrick Dinkelborg 1 collaboration

Heike Pfäffle 1 collaboration

Qi Liu 1 collaboration

Meng Wang 1 collaboration

Kerstin Borgmann 1 collaboration

Jeffrey E Settleman 1 collaboration

Henning Willers 1 collaboration

Anahita Dastur 1 collaboration

AHyun Choi 1 collaboration

Xunqin Yin 1 collaboration

Joseph McClanaghan 1 collaboration

Justine Roderick 1 collaboration

Neha U Patel 1 collaboration

Jessica Boisvert 1 collaboration

Ultan McDermott 1 collaboration

Mathew J Garnett 1 collaboration

Jorge Almenara 1 collaboration

Steven Grant 1 collaboration

Kathryn Rizzo 1 collaboration

Michelle Kelliher 1 collaboration

Anthony C Faber 1 collaboration

Adam C Palmer 1 collaboration

Deborah Plana 1 collaboration

Hui Gao 1 collaboration

Guizhi Yang 1 collaboration

John Green 1 collaboration

Xiamei Zhang 1 collaboration

Margaret E McLaughlin 1 collaboration

Colleen Kowal 1 collaboration

Julie Muszynski 1 collaboration

Caroline Bullock 1 collaboration

Stacy Rivera 1 collaboration

GiNell Elliott 1 collaboration

Paul Fordjour 1 collaboration

Ronald Meyer 1 collaboration

Alice Loo 1 collaboration

Esther Kurth 1 collaboration

Hans Bitter 1 collaboration

William R Sellers 1 collaboration

Juliet A Williams 1 collaboration

Peter K Sorger 1 collaboration