Evangelia Boura

Affiliations

2(nd) Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece.

Publications (42)

High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors Against Mac1 Domain of SARS-CoV-2 Nsp3.

IEEE/ACM transactions on computational biology and bioinformatics

Avec: Chandrabose Selvaraj , Dhurvas Chandrasekaran Dinesh , Umesh Panwar , Evzen Boura , Sanjeev Kumar Singh

Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses.

Archives of virology

Avec: Miroslav Smola , Vladimira Horova , Evzen Boura , Martin Klima

Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses.

Antiviral research

Avec: Eva Konkolova , Milan Dejmek , Hubert Hřebabecký , Michal Šála , Jiří Böserle , Radim Nencka , Evzen Boura

Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.

Journal of biomolecular structure & dynamics

Avec: Chandrabose Selvaraj , Dhurvas Chandrasekaran Dinesh , Umesh Panwar , Rajaram Abhirami , Evzen Boura , Sanjeev Kumar Singh

Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP).

Journal of medicinal chemistry

Avec: Markéta Pimková Polidarová , Petra Břehová , Martin Maxmilian Kaiser , Miroslav Smola , Martin Dračínský , Joshua Smith , Aleš Marek , Milan Dejmek , Michal Šála , Ondrej Gutten , Lubomír Rulíšek , Barbora Novotná , Andrea Brázdová , Zlatko Janeba , Radim Nencka , Evzen Boura , Ondřej Páv , Gabriel Birkuš

Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.

Biochemistry

Avec: Barbora Novotná , Lucie Holá , Monika Staś , Ondrej Gutten , Miroslav Smola , Martin Zavřel , Zdeněk Vavřina , Miloš Buděšínský , Radek Liboska , Florian Chevrier , Juraj Dobiaš , Evzen Boura , Lubomír Rulíšek , Gabriel Birkuš

Osh6 Revisited: Control of PS Transport by the Concerted Actions of PI4P and Sac1 Phosphatase.

Frontiers in molecular biosciences

Avec: Andrea Eisenreichova , Bartosz Różycki , Evzen Boura , Jana Humpolickova

Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase.

Structure (London, England : 1993)

Avec: Kateřina Krejčová , Petra Krafcikova , Martin Klima , Dominika Chalupska , Karel Chalupsky , Eva Zilecka , Evzen Boura

Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases.

European journal of medicinal chemistry

Avec: Mbilo Misehe , Marika Matoušová , Alexandra Dvořáková , Kamil Hercík , Kryštof Škach , Dominika Chalupská , Milan Dejmek , Michal Šála , Miroslav Hájek , Evzen Boura , Helena Mertlíková-Kaiserová , Radim Nencka

Inhibitors of mpox VP39 2'-O methyltransferase efficiently inhibit the monkeypox virus.

Antiviral research

Avec: Michala Zgarbová , Tomas Otava , Jan Silhan , Radim Nencka , Jan Weber , Evzen Boura

Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins.

Scientific reports

Avec: Dominika Chalupska , Bartosz Różycki , Jana Humpolickova , Lenka Faltova , Martin Klima , Evzen Boura

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol.

The Journal of cell biology

Avec: Joshua G Pemberton , Yeun Ju Kim , Jana Humpolickova , Andrea Eisenreichova , Nivedita Sengupta , Daniel J Toth , Evzen Boura , Tamas Balla

Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin.

Nature communications

Avec: Petra Krafcikova , Jan Silhan , Radim Nencka , Evzen Boura

Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics.

Current molecular pharmacology

Avec: Chandrabose Selvaraj , Dhurvas Chandrasekaran Dinesh , Petra Krafcikova , Evzen Boura , Murali Aarthy , Muthuraja Arun Pravin , Sanjeev Kumar Singh

Quality of Life in Patients With Asymptomatic Primary Hyperparathyroidism After Parathyroidectomy: A 3-Year Longitudinal Study.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Avec: Georgios Tzikos , Angeliki Chorti , Sykaras Evangelos , Christina Manani , Fotini Adamidou , Ioannis Tziatzios , Anna Zisi , Fotios Economou , Konstantinos Toulis , Ioannis Pliakos , Antonios Michalopoulos , Theodosios Papavramidisos

High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses.

Molecules (Basel, Switzerland)

Avec: Bara Cihlova , Andrea Huskova , Jiri Böserle , Radim Nencka , Evzen Boura , Jan Silhan

Reviewing Antiviral Research against Viruses Causing Human Diseases - a Structure-Guided Approach.

Current molecular pharmacology

Avec: Arunima Sikdar , Rupali Gupta , Evzen Boura

A Helquat-like Compound as a Potent Inhibitor of Flaviviral and Coronaviral Polymerases.

Molecules (Basel, Switzerland)

Avec: Eva Konkolova , Kateřina Krejčová , Luděk Eyer , Jan Hodek , Michala Zgarbová , Andrea Fořtová , Michael Jirasek , Filip Teply , Paul E Reyes-Gutierrez , Daniel Růžek , Jan Weber , Evzen Boura

The rate of formation and stability of abasic site interstrand crosslinks in the DNA duplex.

DNA repair

Avec: Andrea Huskova , Barbora Landova , Evzen Boura , Jan Silhan

Development of subunit selective substrates for

bioRxiv : the preprint server for biology

Avec: Pavla Fajtova , Brianna M Hurysz , Yukiko Miyamoto , Mateus Serafim , Zhenze Jiang , Diego F Trujillo , Lawrence Liu , Urvashi Somani , Jehad Almaliti , Samuel A Myers , Conor R Caffrey , William H Gerwick , Christopher J Kirk , Evzen Boura , Lars Eckmann , Anthony J O'Donoghue

Conformational ensemble of the full-length SARS-CoV-2 nucleocapsid (N) protein based on molecular simulations and SAXS data.

Biophysical chemistry

Avec: Bartosz Różycki , Evzen Boura

Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.

Antiviral research

Avec: Petr Skvara , Dominika Chalupska , Martin Klima , Jan Kozic , Jan Silhan , Evzen Boura

Structural analysis of the putative SARS-CoV-2 primase complex.

Journal of structural biology

Avec: Eva Konkolova , Martin Klima , Radim Nencka , Evzen Boura

Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory.

Biochemistry

Avec: Zdeněk Vavřina , Ondrej Gutten , Miroslav Smola , Martin Zavřel , Zahra Aliakbar Tehrani , Vilém Charvát , Milan Kožíšek , Evzen Boura , Gabriel Birkuš , Lubomír Rulíšek

Structural Analysis of the OC43 Coronavirus 2'-O-RNA Methyltransferase.

Journal of virology

Avec: Pavel Dostalik , Petra Krafcikova , Jan Silhan , Jan Kozic , Dominika Chalupska , Karel Chalupsky , Evzen Boura

PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.

Science (New York, N.Y.)

Avec: Federico Gulluni , Lorenzo Prever , Huayi Li , Petra Krafcikova , Ilaria Corrado , Wen-Ting Lo , Jean Piero Margaria , Anlu Chen , Maria Chiara De Santis , Sophie J Cnudde , Joseph Fogerty , Alex Yuan , Alberto Massarotti , Nasrin Torabi Sarijalo , Oscar Vadas , Roger L Williams , Marcus Thelen , David R Powell , Markus Schueler , Michael S Wiesener , Tamas Balla , Hagit N Baris , Dov Tiosano , Brian M McDermott , Brian D Perkins , Alessandra Ghigo , Miriam Martini , Volker Haucke , Evzen Boura , Giorgio Roberto Merlo , David A Buchner , Emilio Hirsch

Coronaviral RNA-methyltransferases: function, structure and inhibition.

Nucleic acids research

Avec: Radim Nencka , Jan Silhan , Martin Klima , Tomas Otava , Hugo Kocek , Petra Krafcikova , Evzen Boura

Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology.

Nucleic acids research

Avec: Jiří Holoubek , Klára Bednářová , Jan Haviernik , Ivana Huvarová , Zuzana Dvořáková , Jiří Černý , Martina Outlá , Jiří Salát , Eva Konkol'ová , Evzen Boura , Daniel Růžek , Michaela Vorlíčková , Luděk Eyer , Daniel Renčiuk

Crystal structure of SARS-CoV-2 nsp10-nsp16 in complex with small molecule inhibitors, SS148 and WZ16.

Protein science : a publication of the Protein Society

Avec: Martin Klima , Aliakbar Khalili Yazdi , Fengling Li , Irene Chau , Taraneh Hajian , Albina Bolotokova , H Ümit Kaniskan , Yulin Han , Ke Wang , Deyao Li , Minkui Luo , Jian Jin , Evzen Boura , Masoud Vedadi

Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Jehad Almaliti , Pavla Fajtová , Jaeson Calla , Gregory M LaMonte , Mudong Feng , Frances Rocamora , Sabine Ottilie , Evgenia Glukhov , Evzen Boura , Raymond T Suhandynata , Jeremiah D Momper , Michael K Gilson , Elizabeth A Winzeler , William H Gerwick , Anthony J O'Donoghue

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors.

bioRxiv : the preprint server for biology

Avec: AkshatKumar Nigam , Matthew F D Hurley , Fengling Li , Eva Konkoǐová , Martin Klíma , Jana Trylčová , Robert Pollice , Süleyman Selim Çinaroǧlu , Roni Levin-Konigsberg , Jasemine Handjaya , Matthieu Schapira , Irene Chau , Sumera Perveen , Ho-Leung Ng , H Ümit Kaniskan , Yulin Han , Sukrit Singh , Christoph Gorgulla , Anshul Kundaje , Jian Jin , Vincent A Voelz , Jan Weber , Radim Nencka , Evzen Boura , Masoud Vedadi , Alán Aspuru-Guzik

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.

Structure (London, England : 1993)

Avec: Martin Klima , Milan Dejmek , Vojtech Duchoslav , Andrea Eisenreichova , Michal Sala , Karel Chalupsky , Dominika Chalupska , Barbora Novotná , Gabriel Birkuš , Radim Nencka , Evzen Boura

Structural insights into Acyl-coenzyme A binding domain containing 3 (ACBD3) protein hijacking by picornaviruses.

Protein science : a publication of the Protein Society

Avec: Dominika Chalupska , Bartosz Różycki , Martin Klima , Evzen Boura

Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation.

Journal of structural biology

Avec: Anna Dubankova , Vladimira Horova , Martin Klima , Evzen Boura

No magnesium is needed for binding of the stimulator of interferon genes to cyclic dinucleotides.

Acta crystallographica. Section F, Structural biology communications

Avec: Miroslav Smola , Gabriel Birkus , Evzen Boura

Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses.

Antiviral research

Avec: Anna Dubankova , Evzen Boura

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein.

PLoS pathogens

Avec: Dhurvas Chandrasekaran Dinesh , Dominika Chalupska , Jan Silhan , Eliska Koutna , Radim Nencka , Vaclav Veverka , Evzen Boura

Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease.

Frontiers in chemistry

Avec: Chandrabose Selvaraj , Umesh Panwar , Dhurvas Chandrasekaran Dinesh , Evzen Boura , Poonam Singh , Vikash Kumar Dubey , Sanjeev Kumar Singh

Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit.

Viruses

Avec: Vladimira Horova , Barbora Landova , Jan Hodek , Karel Chalupsky , Petra Krafcikova , Dominika Chalupska , Vojtech Duchoslav , Jan Weber , Evzen Boura , Martin Klima

Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase.

Viruses

Avec: Roberto Benoni , Petra Krafcikova , Marek R Baranowski , Joanna Kowalska , Evzen Boura , Hana Cahová

Effects of biophysical membrane properties on recognition of phosphatidylserine, or phosphatidylinositol 4-phosphate by lipid biosensors LactC2, or P4M.

Biochimie

Avec: Andrea Eisenreichova , Jana Humpolickova , Bartosz Różycki , Evzen Boura , Alena Koukalova

Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold.

Bioorganic & medicinal chemistry letters

Avec: Mbilo Misehe , Martin Klima , Marika Matoušová , Dominika Chalupská , Milan Dejmek , Michal Šála , Helena Mertlíková-Kaiserová , Evzen Boura , Radim Nencka

Réseau de co-auteurs

Evzen Boura 41 collaborations

Martin Klima 12 collaborations

Radim Nencka 12 collaborations

Petra Krafcikova 8 collaborations

Dominika Chalupska 8 collaborations

Jan Silhan 8 collaborations

Dhurvas Chandrasekaran Dinesh 5 collaborations

Miroslav Smola 5 collaborations

Milan Dejmek 5 collaborations

Bartosz Różycki 5 collaborations

Chandrabose Selvaraj 4 collaborations

Sanjeev Kumar Singh 4 collaborations

Michal Šála 4 collaborations

Gabriel Birkuš 4 collaborations

Andrea Eisenreichova 4 collaborations

Jana Humpolickova 4 collaborations

Karel Chalupsky 4 collaborations

Jan Weber 4 collaborations

Umesh Panwar 3 collaborations

Vladimira Horova 3 collaborations

Eva Konkolova 3 collaborations

Ondrej Gutten 3 collaborations

Lubomír Rulíšek 3 collaborations

Barbora Novotná 3 collaborations

Martin Zavřel 2 collaborations

Zdeněk Vavřina 2 collaborations

Kateřina Krejčová 2 collaborations

Mbilo Misehe 2 collaborations

Marika Matoušová 2 collaborations

Dominika Chalupská 2 collaborations

Helena Mertlíková-Kaiserová 2 collaborations

Michala Zgarbová 2 collaborations

Tomas Otava 2 collaborations

Tamas Balla 2 collaborations

Andrea Huskova 2 collaborations

Luděk Eyer 2 collaborations

Jan Hodek 2 collaborations

Daniel Růžek 2 collaborations

Barbora Landova 2 collaborations

Jehad Almaliti 2 collaborations

William H Gerwick 2 collaborations

Anthony J O'Donoghue 2 collaborations

Jan Kozic 2 collaborations

Fengling Li 2 collaborations

Irene Chau 2 collaborations

H Ümit Kaniskan 2 collaborations

Yulin Han 2 collaborations

Jian Jin 2 collaborations

Masoud Vedadi 2 collaborations

Vojtech Duchoslav 2 collaborations

Anna Dubankova 2 collaborations

Hubert Hřebabecký 1 collaboration

Jiří Böserle 1 collaboration

Rajaram Abhirami 1 collaboration

Markéta Pimková Polidarová 1 collaboration

Petra Břehová 1 collaboration

Martin Maxmilian Kaiser 1 collaboration

Martin Dračínský 1 collaboration

Joshua Smith 1 collaboration

Aleš Marek 1 collaboration

Andrea Brázdová 1 collaboration

Zlatko Janeba 1 collaboration

Ondřej Páv 1 collaboration

Lucie Holá 1 collaboration

Monika Staś 1 collaboration

Miloš Buděšínský 1 collaboration

Radek Liboska 1 collaboration

Florian Chevrier 1 collaboration

Juraj Dobiaš 1 collaboration

Eva Zilecka 1 collaboration

Alexandra Dvořáková 1 collaboration

Kamil Hercík 1 collaboration

Kryštof Škach 1 collaboration

Miroslav Hájek 1 collaboration

Lenka Faltova 1 collaboration

Joshua G Pemberton 1 collaboration

Yeun Ju Kim 1 collaboration

Nivedita Sengupta 1 collaboration

Daniel J Toth 1 collaboration

Murali Aarthy 1 collaboration

Muthuraja Arun Pravin 1 collaboration

Georgios Tzikos 1 collaboration

Angeliki Chorti 1 collaboration

Sykaras Evangelos 1 collaboration

Christina Manani 1 collaboration

Fotini Adamidou 1 collaboration

Ioannis Tziatzios 1 collaboration

Anna Zisi 1 collaboration

Fotios Economou 1 collaboration

Konstantinos Toulis 1 collaboration

Ioannis Pliakos 1 collaboration

Antonios Michalopoulos 1 collaboration

Theodosios Papavramidisos 1 collaboration

Bara Cihlova 1 collaboration

Jiri Böserle 1 collaboration

Arunima Sikdar 1 collaboration

Rupali Gupta 1 collaboration

Andrea Fořtová 1 collaboration

Michael Jirasek 1 collaboration

Filip Teply 1 collaboration

Paul E Reyes-Gutierrez 1 collaboration

Pavla Fajtova 1 collaboration

Brianna M Hurysz 1 collaboration

Yukiko Miyamoto 1 collaboration

Mateus Serafim 1 collaboration

Zhenze Jiang 1 collaboration

Diego F Trujillo 1 collaboration

Lawrence Liu 1 collaboration

Urvashi Somani 1 collaboration

Samuel A Myers 1 collaboration

Conor R Caffrey 1 collaboration

Christopher J Kirk 1 collaboration

Lars Eckmann 1 collaboration

Petr Skvara 1 collaboration

Zahra Aliakbar Tehrani 1 collaboration

Vilém Charvát 1 collaboration

Milan Kožíšek 1 collaboration

Pavel Dostalik 1 collaboration

Federico Gulluni 1 collaboration

Lorenzo Prever 1 collaboration

Huayi Li 1 collaboration

Ilaria Corrado 1 collaboration

Wen-Ting Lo 1 collaboration

Jean Piero Margaria 1 collaboration

Anlu Chen 1 collaboration

Maria Chiara De Santis 1 collaboration

Sophie J Cnudde 1 collaboration

Joseph Fogerty 1 collaboration

Alex Yuan 1 collaboration

Alberto Massarotti 1 collaboration

Nasrin Torabi Sarijalo 1 collaboration

Oscar Vadas 1 collaboration

Roger L Williams 1 collaboration

Marcus Thelen 1 collaboration

David R Powell 1 collaboration

Markus Schueler 1 collaboration

Michael S Wiesener 1 collaboration

Hagit N Baris 1 collaboration

Dov Tiosano 1 collaboration

Brian M McDermott 1 collaboration

Brian D Perkins 1 collaboration

Alessandra Ghigo 1 collaboration

Miriam Martini 1 collaboration

Volker Haucke 1 collaboration

Giorgio Roberto Merlo 1 collaboration

David A Buchner 1 collaboration

Emilio Hirsch 1 collaboration

Hugo Kocek 1 collaboration

Jiří Holoubek 1 collaboration

Klára Bednářová 1 collaboration

Jan Haviernik 1 collaboration

Ivana Huvarová 1 collaboration

Zuzana Dvořáková 1 collaboration

Jiří Černý 1 collaboration

Martina Outlá 1 collaboration

Jiří Salát 1 collaboration

Eva Konkol'ová 1 collaboration

Michaela Vorlíčková 1 collaboration

Daniel Renčiuk 1 collaboration

Aliakbar Khalili Yazdi 1 collaboration

Taraneh Hajian 1 collaboration

Albina Bolotokova 1 collaboration

Ke Wang 1 collaboration

Deyao Li 1 collaboration

Minkui Luo 1 collaboration

Pavla Fajtová 1 collaboration

Jaeson Calla 1 collaboration

Gregory M LaMonte 1 collaboration

Mudong Feng 1 collaboration

Frances Rocamora 1 collaboration

Sabine Ottilie 1 collaboration

Evgenia Glukhov 1 collaboration

Raymond T Suhandynata 1 collaboration

Jeremiah D Momper 1 collaboration

Michael K Gilson 1 collaboration

Elizabeth A Winzeler 1 collaboration

AkshatKumar Nigam 1 collaboration

Matthew F D Hurley 1 collaboration

Eva Konkoǐová 1 collaboration

Martin Klíma 1 collaboration

Jana Trylčová 1 collaboration

Robert Pollice 1 collaboration

Süleyman Selim Çinaroǧlu 1 collaboration

Roni Levin-Konigsberg 1 collaboration

Jasemine Handjaya 1 collaboration

Matthieu Schapira 1 collaboration

Sumera Perveen 1 collaboration

Ho-Leung Ng 1 collaboration

Sukrit Singh 1 collaboration

Christoph Gorgulla 1 collaboration

Anshul Kundaje 1 collaboration

Vincent A Voelz 1 collaboration

Alán Aspuru-Guzik 1 collaboration

Michal Sala 1 collaboration

Gabriel Birkus 1 collaboration

Eliska Koutna 1 collaboration

Vaclav Veverka 1 collaboration

Poonam Singh 1 collaboration

Vikash Kumar Dubey 1 collaboration

Roberto Benoni 1 collaboration

Marek R Baranowski 1 collaboration

Joanna Kowalska 1 collaboration

Hana Cahová 1 collaboration

Alena Koukalova 1 collaboration