E Papaemmanuil

Publications (71)

Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.

The Journal of experimental medicine

Avec: Faisal Basheer , George Giotopoulos , Eshwar Meduri , Haiyang Yun , Milena Mazan , Daniel Sasca , Paolo Gallipoli , Ludovica Marando , Malgorzata Gozdecka , Ryan Asby , Olivia Sheppard , Monika Dudek , Lars Bullinger , Hartmut Döhner , Richard Dillon , Sylvie Freeman , Oliver Ottmann , Alan Burnett , Nigel Russell , Elli Papaemmanuil , Robert Hills , Peter Campbell , George S Vassiliou , Brian J P Huntly

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes.

Nature medicine

Avec: Elsa Bernard , Yasuhito Nannya , Robert P Hasserjian , Sean M Devlin , Heinz Tuechler , Juan S Medina-Martinez , Tetsuichi Yoshizato , Yusuke Shiozawa , Ryunosuke Saiki , Luca Malcovati , Max F Levine , Juan E Arango , Yangyu Zhou , Francesc Solé , Catherine A Cargo , Detlef Haase , Maria Creignou , Ulrich Germing , Yanming Zhang , Gunes Gundem , Araxe Sarian , Arjan A van de Loosdrecht , Martin Jädersten , Magnus Tobiasson , Olivier Kosmider , Matilde Y Follo , Felicitas Thol , Ronald F Pinheiro , Valeria Santini , Ioannis Kotsianidis , Jacqueline Boultwood , Fabio P S Santos , Julie Schanz , Senji Kasahara , Takayuki Ishikawa , Hisashi Tsurumi , Akifumi Takaori-Kondo , Toru Kiguchi , Chantana Polprasert , John M Bennett , Virginia M Klimek , Michael R Savona , Monika Belickova , Christina Ganster , Laura Palomo , Guillermo Sanz , Lionel Ades , Matteo Giovanni Della Porta , Harold K Elias , Alexandra G Smith , Yesenia Werner , Minal Patel , Agnès Viale , Katelynd Vanness , Donna S Neuberg , Kristen E Stevenson , Kamal Menghrajani , Kelly L Bolton , Pierre Fenaux , Andrea Pellagatti , Uwe Platzbecker , Michael Heuser , Peter Valent , Shigeru Chiba , Yasushi Miyazaki , Carlo Finelli , Maria Teresa Voso , Lee-Yung Shih , Michaela Fontenay , Joop H Jansen , José Cervera , Yoshiko Atsuta , Norbert Gattermann , Benjamin L Ebert , Rafael Bejar , Peter L Greenberg , Mario Cazzola , Eva Hellström-Lindberg , Seishi Ogawa , Elli Papaemmanuil

The Clinical Management of Clonal Hematopoiesis: Creation of a Clonal Hematopoiesis Clinic.

Hematology/oncology clinics of North America

Avec: Kelly L Bolton , Ahmet Zehir , Ryan N Ptashkin , Minal Patel , Dipti Gupta , Robert Sidlow , Elli Papaemmanuil , Michael F Berger , Ross L Levine

Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea.

Blood

Avec: Abdulraheem Yacoub , John Mascarenhas , Heidi Kosiorek , Josef T Prchal , Dmitry Berenzon , Maria R Baer , Ellen Ritchie , Richard T Silver , Craig Kessler , Elliott Winton , Maria Chiara Finazzi , Alessandro Rambaldi , Alessandro M Vannucchi , David Leibowitz , Damiano Rondelli , Murat O Arcasoy , Rosalind Catchatourian , Joseph Vadakara , Vittorio Rosti , Elizabeth Hexner , Marina Kremyanskaya , Lonette Sandy , Joseph Tripodi , Vesna Najfeld , Noushin Farnoud , Elli Papaemmanuil , Mohamed Salama , Rona Singer-Weinberg , Raajit Rampal , Judith D Goldberg , Tiziano Barbui , Ruben Mesa , Amylou C Dueck , Ronald Hoffman

Revealing the impact of structural variants in multiple myeloma.

Blood cancer discovery

Avec: Even H Rustad , Venkata D Yellapantula , Dominik Glodzik , Kylee H Maclachlan , Benjamin Diamond , Eileen M Boyle , Cody Ashby , Patrick Blaney , Gunes Gundem , Malin Hultcrantz , Daniel Leongamornlert , Nicos Angelopoulos , Luca Agnelli , Daniel Auclair , Yanming Zhang , Ahmet Dogan , Niccolò Bolli , Elli Papaemmanuil , Kenneth C Anderson , Philippe Moreau , Hervé Avet-Loiseau , Nikhil C Munshi , Jonathan J Keats , Peter J Campbell , Gareth J Morgan , Ola Landgren , Francesco Maura

Modulation of IL-6/STAT3 signaling axis in CD4+FOXP3- T cells represents a potential antitumor mechanism of azacitidine.

Blood advances

Avec: Eleftheria Lamprianidou , Chryssoula Kordella , Anastasiya Kazachenka , Emmanouela Zoulia , Elsa Bernard , Anastasia Filia , Stamatia Laidou , Panayiotis Garantziotis , Theodoros P Vassilakopoulos , Sotirios G Papageorgiou , Vassiliki Pappa , Athanasios G Galanopoulos , Nora Viniou , Evangelia Nakou , Lydia Kalafati , Anastasia Chatzidimitriou , George Kassiotis , Elli Papaemmanuil , Ioannis Mitroulis , Ioannis Kotsianidis

Capture Rate of V(D)J Sequencing for Minimal Residual Disease Detection in Multiple Myeloma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Malin Hultcrantz , Even H Rustad , Venkata Yellapantula , Allison Jacob , Theresia Akhlaghi , Neha Korde , Sham Mailankody , Alexander M Lesokhin , Hani Hassoun , Eric L Smith , Oscar B Lahoud , Heather J Landau , Gunjan L Shah , Michael Scordo , David J Chung , Sergio Giralt , Elli Papaemmanuil , Ola Landgren

Molecular International Prognostic Scoring System for Myelodysplastic Syndromes.

NEJM evidence

Avec: Elsa Bernard , Heinz Tuechler , Peter L Greenberg , Robert P Hasserjian , Juan E Arango Ossa , Yasuhito Nannya , Sean M Devlin , Maria Creignou , Philippe Pinel , Lily Monnier , Gunes Gundem , Juan S Medina-Martinez , Dylan Domenico , Martin Jädersten , Ulrich Germing , Guillermo Sanz , Arjan A van de Loosdrecht , Olivier Kosmider , Matilde Y Follo , Felicitas Thol , Lurdes Zamora , Ronald F Pinheiro , Andrea Pellagatti , Harold K Elias , Detlef Haase , Christina Ganster , Lionel Ades , Magnus Tobiasson , Laura Palomo , Matteo Giovanni Della Porta , Akifumi Takaori-Kondo , Takayuki Ishikawa , Shigeru Chiba , Senji Kasahara , Yasushi Miyazaki , Agnes Viale , Kety Huberman , Pierre Fenaux , Monika Belickova , Michael R Savona , Virginia M Klimek , Fabio P S Santos , Jacqueline Boultwood , Ioannis Kotsianidis , Valeria Santini , Francesc Solé , Uwe Platzbecker , Michael Heuser , Peter Valent , Kazuma Ohyashiki , Carlo Finelli , Maria Teresa Voso , Lee-Yung Shih , Michaela Fontenay , Joop H Jansen , José Cervera , Norbert Gattermann , Benjamin L Ebert , Rafael Bejar , Luca Malcovati , Mario Cazzola , Seishi Ogawa , Eva Hellström-Lindberg , Elli Papaemmanuil

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.

Blood

Avec: Daniel A Arber , Attilio Orazi , Robert P Hasserjian , Michael J Borowitz , Katherine R Calvo , Hans-Michael Kvasnicka , Sa A Wang , Adam Bagg , Tiziano Barbui , Susan Branford , Carlos E Bueso-Ramos , Jorge E Cortes , Paola Dal Cin , Courtney D DiNardo , Hervé Dombret , Eric J Duncavage , Benjamin L Ebert , Elihu H Estey , Fabio Facchetti , Kathryn Foucar , Naseema Gangat , Umberto Gianelli , Lucy A Godley , Nicola Gökbuget , Jason Gotlib , Eva Hellström-Lindberg , Gabriela S Hobbs , Ronald Hoffman , Elias J Jabbour , Jean-Jacques Kiladjian , Richard A Larson , Michelle M Le Beau , Mignon L-C Loh , Bob Löwenberg , Elizabeth Macintyre , Luca Malcovati , Charles G Mullighan , Charlotte Niemeyer , Olatoyosi M Odenike , Seishi Ogawa , Alberto Orfao , Elli Papaemmanuil , Francesco Passamonti , Kimmo Porkka , Ching-Hon Pui , Jerald P Radich , Andreas Reiter , Maria Rozman , Martina Rudelius , Michael R Savona , Charles A Schiffer , Annette Schmitt-Graeff , Akiko Shimamura , Jorge Sierra , Wendy A Stock , Richard M Stone , Martin S Tallman , Jürgen Thiele , Hwei-Fang Tien , Alexandar Tzankov , Alessandro M Vannucchi , Paresh Vyas , Andrew H Wei , Olga K Weinberg , Agnieszka Wierzbowska , Mario Cazzola , Hartmut Döhner , Ayalew Tefferi

NIPBL::NACC1 Fusion Hepatic Carcinoma.

The American journal of surgical pathology

Avec: Erika Hissong , Majd Al Assaad , Munita Bal , Katelyn A Reed , Adele Fornelli , Max F Levine , Gunes Gundem , Alissa Semaan , Christine E Orr , Uma Sakhadeo , Jyothi Manohar , Michael Sigouros , David Wilkes , Andrea Sboner , Elizabeth A Montgomery , Rondell P Graham , Juan S Medina-Martínez , Nicolas Robine , Jiayun M Fang , Eun-Young K Choi , Maria Westerhoff , Jesús Delgado-de la Mora , Patricia Caudell , Rhonda K Yantiss , Elli Papaemmanuil , Olivier Elemento , Carlie Sigel , José Jessurun , Juan Miguel Mosquera

Molecular Taxonomy of Myelodysplastic Syndromes and its Clinical Implications.

Blood

Avec: Elsa Bernard , Robert P Hasserjian , Peter L Greenberg , Juan Esteban Arango Ossa , Maria Creignou , Heinz Tuechler , Jesús Gutiérrez-Abril , Dylan Domenico , Juan Santiago Medina-Martinez , Max Fine Levine , Konstantinos Liosis , Noushin Farnoud , Maria Sirenko , Martin Jädersten , Ulrich Germing , Guillermo F Sanz , Arjan A Van de Loosdrecht , Yasuhito Nannya , Olivier Kosmider , Matilde Y Follo , Felicitas R Thol , Lurdes Zamora , Ronald Feitosa Pinheiro , Andrea Pellagatti , Harold Kunal Elias , Detlef Thomas Haase , Christina Ganster , Lionel Ades , Magnus Tobiasson , Laura Palomo , Matteo Giovanni Della Porta , Pierre Fenaux , Monika Belickova , Michael R Savona , Virginia Klimek , Fabio P S Santos , Jacqueline Boultwood , Ioannis Kotsianidis , Valeria Santini , Francesc Sole , Uwe Platzbecker , Michael Heuser , Peter Valent , Carlo Finelli , Maria Teresa Voso , Lee Yung Shih , Michaela Fontenay , Joop H Jansen , José Cervera , Norbert Gattermann , Benjamin L Ebert , Rafael Bejar , Luca Malcovati , Seishi Ogawa , Mario Cazzola , Eva S Hellstrom-Lindberg , Elli Papaemmanuil

RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.

Blood advances

Avec: Anna L Brown , Peer Arts , Catherine L Carmichael , Milena Babic , Julia Dobbins , Chan-Eng Chong , Andreas W Schreiber , Jinghua Feng , Kerry Phillips , Paul P S Wang , Thuong Ha , Claire C Homan , Sarah L King-Smith , Lesley Rawlings , Cassandra Vakulin , Andrew Dubowsky , Jessica Burdett , Sarah Moore , Grace McKavanagh , Denae Henry , Amanda Wells , Belinda Mercorella , Mario Nicola , Jeffrey Suttle , Ella Wilkins , Xiao-Chun Li , Joelle Michaud , Peter Brautigan , Ping Cannon , Meryl Altree , Louise Jaensch , Miriam Fine , Carolyn Butcher , Richard J D'Andrea , Ian D Lewis , Devendra K Hiwase , Elli Papaemmanuil , Marshall S Horwitz , Georges Natsoulis , Hugh Y Rienhoff , Nigel Patton , Sally Mapp , Rachel Susman , Susan Morgan , Julian Cooney , Mark Currie , Uday Popat , Tilmann Bochtler , Shai Izraeli , Kenneth Bradstock , Lucy A Godley , Alwin Krämer , Stefan Fröhling , Andrew H Wei , Cecily Forsyth , Helen Mar Fan , Nicola K Poplawski , Christopher N Hahn , Hamish S Scott

Accelerated single cell seeding in relapsed multiple myeloma.

Nature communications

Avec: Heather J Landau , Venkata Yellapantula , Benjamin T Diamond , Even H Rustad , Kylee H Maclachlan , Gunes Gundem , Juan Medina-Martinez , Juan Arango Ossa , Max F Levine , Yangyu Zhou , Rajya Kappagantula , Priscilla Baez , Marc Attiyeh , Alvin Makohon-Moore , Lance Zhang , Eileen M Boyle , Cody Ashby , Patrick Blaney , Minal Patel , Yanming Zhang , Ahmet Dogan , David J Chung , Sergio Giralt , Oscar B Lahoud , Jonathan U Peled , Michael Scordo , Gunjan Shah , Hani Hassoun , Neha S Korde , Alexander M Lesokhin , Sydney Lu , Sham Mailankody , Urvi Shah , Eric Smith , Malin L Hultcrantz , Gary A Ulaner , Frits van Rhee , Gareth J Morgan , Ola Landgren , Elli Papaemmanuil , Christine Iacobuzio-Donahue , Francesco Maura

Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma.

PloS one

Avec: Even H Rustad , Malin Hultcrantz , Venkata D Yellapantula , Theresia Akhlaghi , Caleb Ho , Maria E Arcila , Mikhail Roshal , Akshar Patel , Denise Chen , Sean M Devlin , Austin Jacobsen , Ying Huang , Jeffrey E Miller , Elli Papaemmanuil , Ola Landgren

Molecular underpinnings of clinical disparity patterns in African American vs. Caucasian American multiple myeloma patients.

Blood cancer journal

Avec: Dickran Kazandjian , Elizabeth Hill , Malin Hultcrantz , Evan H Rustad , Venkata Yellapantula , Theresia Akhlaghi , Neha Korde , Sham Mailankody , Alex Dew , Elli Papaemmanuil , Irina Maric , Mary Kwok , Ola Landgren

Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs.

Blood advances

Avec: Georgios Asimomitis , André G Deslauriers , Andriana G Kotini , Elsa Bernard , Davide Esposito , Malgorzata Olszewska , Nikolaos Spyrou , Juan Arango Ossa , Teresa Mortera-Blanco , Richard Koche , Yasuhito Nannya , Luca Malcovati , Seishi Ogawa , Mario Cazzola , Stuart A Aaronson , Eva Hellström-Lindberg , Elli Papaemmanuil , Eirini P Papapetrou

Isabl Platform, a digital biobank for processing multimodal patient data.

BMC bioinformatics

Avec: Juan S Medina-Martínez , Juan E Arango-Ossa , Max F Levine , Yangyu Zhou , Gunes Gundem , Andrew L Kung , Elli Papaemmanuil

Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Francesco Maura , Benjamin Diamond , Kylee H Maclachlan , Andriy Derkach , Venkata D Yellapantula , Even H Rustad , Malin Hultcrantz , Urvi A Shah , Jessica Hong , Heather J Landau , Christine A Iacobuzio-Donahue , Elli Papaemmanuil , Shani Irby , Laura Crowley , Michael Crane , Mayris P Webber , David G Goldfarb , Rachel Zeig-Owens , Orsi Giricz , Amit Verma , David J Prezant , Ahmet Dogan , Sohrab P Shah , Yanming Zhang , Ola Landgren

Timing the initiation of multiple myeloma.

Nature communications

Avec: Even H Rustad , Venkata Yellapantula , Daniel Leongamornlert , Niccolò Bolli , Guy Ledergor , Ferran Nadeu , Nicos Angelopoulos , Kevin J Dawson , Thomas J Mitchell , Robert J Osborne , Bachisio Ziccheddu , Cristiana Carniti , Vittorio Montefusco , Paolo Corradini , Kenneth C Anderson , Philippe Moreau , Elli Papaemmanuil , Ludmil B Alexandrov , Xose S Puente , Elias Campo , Reiner Siebert , Herve Avet-Loiseau , Ola Landgren , Nikhil Munshi , Peter J Campbell , Francesco Maura

Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Gabriele Todisco , Maria Creignou , Elsa Bernard , Ann-Charlotte Björklund , Pedro Luis Moura , Bianca Tesi , Teresa Mortera-Blanco , Birgitta Sander , Monika Jansson , Gunilla Walldin , Indira Barbosa , Susanne E Reinsbach , Isabel Juliana Hofman , Christer Nilsson , Tetsuichi Yoshizato , Marios Dimitriou , David Chang , Svannildur Olafsdottir , Sigita Venckute Larsson , Magnus Tobiasson , Luca Malcovati , Petter Woll , Sten Eirik W Jacobsen , Elli Papaemmanuil , Eva Hellström-Lindberg

Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of

bioRxiv : the preprint server for biology

Avec: C K Brierley , B H Yip , G Orlando , H Goyal , S Wen , J Wen , M F Levine , G M Jakobsdottir , A Rodriguez-Meira , A Adamo , M Bashton , A Hamblin , S A Clark , J O'Sullivan , L Murphy , A A Olijnik , A Cotton , S Narina , S M Pruett-Miller , A Enshaei , C Harrison , M Drummond , S Knapper , A Tefferi , I Antony-Debré , S Thongjuea , D C Wedge , S Constantinescu , B Psaila , J D Crispino , A J Mead

Predicting cytopenias, progression, and survival in patients with clonal cytopenia of undetermined significance: a prospective cohort study.

The Lancet. Haematology

Avec: Catherine Cargo , Elsa Bernard , Tumas Beinortas , Kelly L Bolton , Paul Glover , Helen Warren , Daniel Payne , Rukhsaar Ali , Alesia Khan , Mike Short , Suzan Van Hoppe , Alex Smith , Jan Taylor , Paul Evans , Elli Papaemmanuil , Simon Crouch

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures.

Blood

Avec: Benjamin Diamond , Bachisio Ziccheddu , Kylee Maclachlan , Justin Taylor , Eileen Boyle , Juan Arango Ossa , Jacob Jahn , Maurizio Affer , Tulasigeri M Totiger , David Coffey , Namrata Chandhok , Justin Watts , Luisa Cimmino , Sydney X Lu , Niccolò Bolli , Kelly Bolton , Heather Landau , Jae H Park , Karuna Ganesh , Andrew McPherson , Mikkael A Sekeres , Alexander Lesokhin , David J Chung , Yanming Zhang , Caleb Ho , Mikhail Roshal , Jeffrey Tyner , Stephen Nimer , Elli Papaemmanuil , Saad Usmani , Gareth Morgan , Ola Landgren , Francesco Maura

Clonal hematopoiesis is associated with risk of severe Covid-19.

medRxiv : the preprint server for health sciences

Avec: Kelly L Bolton , Youngil Koh , Michael B Foote , Hogune Im , Justin Jee , Choong Hyun Sun , Anton Safonov , Ryan Ptashkin , Joon Ho Moon , Ji Yeon Lee , Jongtak Jung , Chang Kyung Kang , Kyoung-Ho Song , Pyeong Gyun Choe , Wan Beom Park , Hong Bin Kim , Myoung-Don Oh , Han Song , Sugyeong Kim , Minal Patel , Andriy Derkach , Erika Gedvilaite , Kaitlyn A Tkachuk , Lior Z Braunstein , Teng Gao , Elli Papaemmanuil , N Esther Babady , Melissa S Pessin , Mini Kamboj , Luis A Diaz , Marc Ladanyi , Michael J Rauh , Pradeep Natarajan , Mitchell J Machiela , Philip Awadalla , Vijai Joseph , Kenneth Offit , Larry Norton , Michael F Berger , Ross L Levine , Eu Suk Kim , Nam Joong Kim , Ahmet Zehir

Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma.

eLife

Avec: Jianing Xu , Ed Reznik , Ho-Joon Lee , Gunes Gundem , Philip Jonsson , Judy Sarungbam , Anna Bialik , Francisco Sanchez-Vega , Chad J Creighton , Jake Hoekstra , Li Zhang , Peter Sajjakulnukit , Daniel Kremer , Zachary Tolstyka , Jozefina Casuscelli , Steve Stirdivant , Jie Tang , Nikolaus Schultz , Paul Jeng , Yiyu Dong , Wenjing Su , Emily H Cheng , Paul Russo , Jonathan A Coleman , Elli Papaemmanuil , Ying-Bei Chen , Victor E Reuter , Chris Sander , Scott R Kennedy , James J Hsieh , Costas A Lyssiotis , Satish K Tickoo , A Ari Hakimi

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Cancer cell

Avec: Maurice Labuhn , Kelly Perkins , Sören Matzk , Leila Varghese , Catherine Garnett , Elli Papaemmanuil , Marlen Metzner , Alison Kennedy , Vyacheslav Amstislavskiy , Thomas Risch , Raj Bhayadia , David Samulowski , David Cruz Hernandez , Bilyana Stoilova , Valentina Iotchkova , Udo Oppermann , Carina Scheer , Kenichi Yoshida , Adrian Schwarzer , Jeffrey W Taub , John D Crispino , Mitchell J Weiss , Yasuhide Hayashi , Takashi Taga , Etsuro Ito , Seishi Ogawa , Dirk Reinhardt , Marie-Laure Yaspo , Peter J Campbell , Irene Roberts , Stefan N Constantinescu , Paresh Vyas , Dirk Heckl , Jan-Henning Klusmann

Single cell analysis of clonal architecture in acute myeloid leukaemia.

Leukemia

Avec: Nicola Potter , Farideh Miraki-Moud , Luca Ermini , Ian Titley , Gowri Vijayaraghavan , Elli Papaemmanuil , Peter Campbell , John Gribben , David Taussig , Mel Greaves

11p15.5 epimutations in children with Wilms tumor and hepatoblastoma detected in peripheral blood.

Cancer

Avec: Elise M Fiala , Michael V Ortiz , Jennifer A Kennedy , Dominik Glodzik , Megan Harlan Fleischut , Kelly A Duffy , Evan R Hathaway , Todd Heaton , Justin T Gerstle , Peter Steinherz , Neerav Shukla , Nicole McNeer , Kaitlyn Tkachuk , Nancy Bouvier , Karen Cadoo , Maria I Carlo , Alicia Latham , Marianne Dubard Gault , Vijai Joseph , Yelena Kemel , Alex Kentsis , Zsofia Stadler , Michael La Quaglia , Elli Papaemmanuil , Danielle Friedman , Arupa Ganguly , Andrew Kung , Kenneth Offit , Jennifer M Kalish , Michael F Walsh

Blood cancer discovery

Avec: Ellen M Beauchamp , Matthew Leventhal , Elsa Bernard , Emma R Hoppe , Gabriele Todisco , Maria Creignou , Anna Gallì , Cecilia A Castellano , Marie McConkey , Akansha Tarun , Waihay Wong , Monica Schenone , Caroline Stanclift , Benjamin Tanenbaum , Edyta Malolepsza , Björn Nilsson , Alexander G Bick , Joshua S Weinstock , Mendy Miller , Abhishek Niroula , Andrew Dunford , Amaro Taylor-Weiner , Timothy Wood , Alex Barbera , Shankara Anand , Bruce M Psaty , Pinkal Desai , Michael H Cho , Andrew D Johnson , Ruth Loos , Auteur inconnu , Daniel G MacArthur , Monkol Lek , Auteur inconnu , Donna S Neuberg , Kasper Lage , Steven A Carr , Eva Hellstrom-Lindberg , Luca Malcovati , Elli Papaemmanuil , Chip Stewart , Gad Getz , Robert K Bradley , Siddhartha Jaiswal , Benjamin L Ebert

Association of BRAF V600E mutations with vasoactive intestinal peptide syndrome in MYCN-amplified neuroblastoma.

Pediatric blood & cancer

Avec: Sanam Shahid , Brian H Kushner , Shakeel Modak , Ellen M Basu , Elyssa M Rubin , Gunes Gundem , Elli Papaemmanuil , Stephen S Roberts

Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 study.

Leukemia

Avec: Anthony V Moorman , Emilio Barretta , Ellie R Butler , Eleanor J Ward , Katie Twentyman , Amy A Kirkwood , Amir Enshaei , Claire Schwab , Tom Creasey , Daniel Leongamornlert , Elli Papaemmanuil , Pip Patrick , Laura Clifton-Hadley , Bela Patel , Tobias Menne , Andrew K McMillan , Christine J Harrison , Clare J Rowntree , David I Marks , Adele K Fielding

Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes.

Blood

Avec: Maria Sirenko , Elsa Bernard , Maria Creignou , Dylan Domenico , Andrea Farina , Juan Esteban Arango Ossa , Olivier Kosmider , Robert P Hasserjian , Martin Jädersten , Ulrich Germing , Guillermo F Sanz , Arjan A van de Loosdrecht , Carmelo Gurnari , Matilde Y Follo , Felicitas R Thol , Lurdes Zamora , Andrea Pellagatti , Harold Kunal Elias , Detlef Thomas Haase , Birgitta Sander , Elisa Orna , Katharina Zoldan , Lea Naomi Eder , Wolfgang R Sperr , Renate Thalhammer , Christina Ganster , Lionel Adès , Magnus Tobiasson , Laura Palomo , Matteo Giovanni Della Porta , Kety H Huberman , Pierre Fenaux , Monika Belickova , Michael R Savona , Virginia Klimek , Fabio P S Santos , Jacqueline Boultwood , Ioannis Kotsianidis , Valeria Santini , Francesc Sole , Uwe Platzbecker , Michael Heuser , Peter Valent , Carlo Finelli , Maria Teresa Voso , Lee Yung Shih , Seishi Ogawa , Michaela Fontenay , Joop H Jansen , José Cervera , Benjamin L Ebert , Rafael Bejar , Peter L Greenberg , Norbert Gattermann , Luca Malcovati , Mario Cazzola , David B Beck , Eva S Hellstrom-Lindberg , Elli Papaemmanuil , Ronald Feitosa Pinheiro

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.

Blood

Avec: Eric J Duncavage , Adam Bagg , Robert P Hasserjian , Courtney D DiNardo , Lucy A Godley , Ilaria Iacobucci , Siddhartha Jaiswal , Luca Malcovati , Alessandro M Vannucchi , Keyur P Patel , Daniel A Arber , Maria E Arcila , Rafael Bejar , Nancy Berliner , Michael J Borowitz , Susan Branford , Anna L Brown , Catherine A Cargo , Hartmut Döhner , Brunangelo Falini , Guillermo Garcia-Manero , Torsten Haferlach , Eva Hellström-Lindberg , Annette S Kim , Jeffery M Klco , Rami Komrokji , Mignon Lee-Cheun Loh , Sanam Loghavi , Charles G Mullighan , Seishi Ogawa , Attilio Orazi , Elli Papaemmanuil , Andreas Reiter , David M Ross , Michael Savona , Akiko Shimamura , Radek C Skoda , Francesc Solé , Richard M Stone , Ayalew Tefferi , Matthew J Walter , David Wu , Benjamin L Ebert , Mario Cazzola

Waldenström macroglobulinemia whole genome reveals prolonged germinal center activity and late copy number aberrations.

Blood advances

Avec: Kylee H Maclachlan , Tina Bagratuni , Efstathios Kastritis , Bachisio Ziccheddu , Sydney Lu , Venkata Yellapantula , Chris Famulare , Kimon Argyropoulos , Andriy Derkach , Elli Papaemmanuil , Ahmet Dogan , Alexander Lesokhin , Saad Z Usmani , C Ola Landgren , Lia M Palomba , Francesco Maura , Meletios A Dimopoulos

Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia.

Blood advances

Avec: Daniel Leongamornlert , Jesús Gutiérrez-Abril , SooWah Lee , Emilio Barretta , Thomas Creasey , Gunes Gundem , Max F Levine , Juan E Arango-Ossa , Konstantinos Liosis , Juan S Medina-Martinez , Krisztina Zuborne Alapi , Amy A Kirkwood , Laura Clifton-Hadley , Pip Patrick , David Jones , Laura O'Neill , Adam P Butler , Christine J Harrison , Peter Campbell , Bela Patel , Anthony V Moorman , Adele K Fielding , Elli Papaemmanuil

Clonal evolution during metastatic spread in high-risk neuroblastoma.

Nature genetics

Avec: Gunes Gundem , Max F Levine , Stephen S Roberts , Irene Y Cheung , Juan S Medina-Martínez , Yi Feng , Juan E Arango-Ossa , Loic Chadoutaud , Mathieu Rita , Georgios Asimomitis , Joe Zhou , Daoqi You , Nancy Bouvier , Barbara Spitzer , David B Solit , Filemon Dela Cruz , Michael P LaQuaglia , Brian H Kushner , Shakeel Modak , Neerav Shukla , Christine A Iacobuzio-Donahue , Andrew L Kung , Nai-Kong V Cheung , Elli Papaemmanuil

Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia.

Blood advances

Avec: Joseph G W McCarter , David Nemirovsky , Christopher A Famulare , Noushin Farnoud , Abhinita S Mohanty , Zoe S Stone-Molloy , Jordan Chervin , Brian J Ball , Zachary D Epstein-Peterson , Maria E Arcila , Aaron J Stonestrom , Andrew Dunbar , Sheng F Cai , Jacob L Glass , Mark B Geyer , Raajit K Rampal , Ellin Berman , Omar I Abdel-Wahab , Eytan M Stein , Martin S Tallman , Ross L Levine , Aaron D Goldberg , Elli Papaemmanuil , Yanming Zhang , Mikhail Roshal , Andriy Derkach , Wenbin Xiao

The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.

Cold Spring Harbor molecular case studies

Avec: Majd Al Assaad , Gunes Gundem , Benjamin Liechty , Andrea Sboner , Juan Medina , Elli Papaemmanuil , Cora N Sternberg , Asher Marks , Mark M Souweidane , Jeffrey P Greenfield , Ivy Tran , Matija Snuderl , Oliver Elemento , Marcin Imielinski , David J Pisapia , Juan Miguel Mosquera

SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS.

Blood

Avec: Luca Malcovati , Kristen Stevenson , Elli Papaemmanuil , Donna Neuberg , Rafael Bejar , Jacqueline Boultwood , David T Bowen , Peter J Campbell , Benjamin L Ebert , Pierre Fenaux , Torsten Haferlach , Michael Heuser , Joop H Jansen , Rami S Komrokji , Jaroslaw P Maciejewski , Matthew J Walter , Michaela Fontenay , Guillermo Garcia-Manero , Timothy A Graubert , Aly Karsan , Manja Meggendorfer , Andrea Pellagatti , David A Sallman , Michael R Savona , Mikkael A Sekeres , David P Steensma , Sudhir Tauro , Felicitas Thol , Paresh Vyas , Arjan A Van de Loosdrecht , Detlef Haase , Heinz Tüchler , Peter L Greenberg , Seishi Ogawa , Eva Hellstrom-Lindberg , Mario Cazzola

Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression.

Genome medicine

Avec: Anastasiya Kazachenka , George R Young , Jan Attig , Chrysoula Kordella , Eleftheria Lamprianidou , Emmanuela Zoulia , George Vrachiolias , Menelaos Papoutselis , Elsa Bernard , Elli Papaemmanuil , Ioannis Kotsianidis , George Kassiotis

Comprehensive detection of recurring genomic abnormalities: a targeted sequencing approach for multiple myeloma.

Blood cancer journal

Avec: Venkata Yellapantula , Malin Hultcrantz , Even H Rustad , Ester Wasserman , Dory Londono , Robert Cimera , Amanda Ciardiello , Heather Landau , Theresia Akhlaghi , Sham Mailankody , Minal Patel , Juan Santiago Medina-Martinez , Juan Esteban Arango Ossa , Max Fine Levine , Niccolo Bolli , Francesco Maura , Ahmet Dogan , Elli Papaemmanuil , Yanming Zhang , Ola Landgren

Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma.

American journal of hematology

Avec: Even H Rustad , Kristine Misund , Elsa Bernard , Eivind Coward , Venkata D Yellapantula , Malin Hultcrantz , Caleb Ho , Dickran Kazandjian , Neha Korde , Sham Mailankody , Jonathan J Keats , Theresia Akhlaghi , Aaron D Viny , David J Mayman , Kaitlin Carroll , Minal Patel , Christopher A Famulare , Davine Hofste Op Bruinink , Kasey Hutt , Austin Jacobsen , Ying Huang , Jeffrey E Miller , Francesco Maura , Elli Papaemmanuil , Anders Waage , Maria E Arcila , Ola Landgren

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies.

Blood

Avec: Daniel Sasca , Haiyang Yun , George Giotopoulos , Jakub Szybinski , Theo Evan , Nicola K Wilson , Moritz Gerstung , Paolo Gallipoli , Anthony R Green , Robert Hills , Nigel Russell , Cameron S Osborne , Elli Papaemmanuil , Berthold Göttgens , Peter Campbell , Brian J P Huntly

Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis.

Nature communications

Avec: Teng Gao , Ryan Ptashkin , Kelly L Bolton , Maria Sirenko , Christopher Fong , Barbara Spitzer , Kamal Menghrajani , Juan E Arango Ossa , Yangyu Zhou , Elsa Bernard , Max Levine , Juan S Medina Martinez , Yanming Zhang , Sebastià Franch-Expósito , Minal Patel , Lior Z Braunstein , Daniel Kelly , Mariko Yabe , Ryma Benayed , Nicole M Caltabellotta , John Philip , Ederlinda Paraiso , Simon Mantha , David B Solit , Luis A Diaz , Michael F Berger , Virginia Klimek , Ross L Levine , Ahmet Zehir , Sean M Devlin , Elli Papaemmanuil

Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor.

Molecular cancer research : MCR

Avec: Emily K Slotkin , Anita S Bowman , Max F Levine , Filemon Dela Cruz , Diego F Coutinho , Glorymar I Sanchez , Nestor Rosales , Shakeel Modak , William D Tap , Mrinal M Gounder , Katherine A Thornton , Nancy Bouvier , Daoqi You , Gunes Gundem , Justin T Gerstle , Todd E Heaton , Michael P LaQuaglia , Leonard H Wexler , Paul A Meyers , Andrew L Kung , Elli Papaemmanuil , Ahmet Zehir , Marc Ladanyi , Neerav Shukla

Clonal hematopoiesis is associated with risk of severe Covid-19.

Nature communications

Avec: Kelly L Bolton , Youngil Koh , Michael B Foote , Hogune Im , Justin Jee , Choong Hyun Sun , Anton Safonov , Ryan Ptashkin , Joon Ho Moon , Ji Yeon Lee , Jongtak Jung , Chang Kyung Kang , Kyoung-Ho Song , Pyoeng Gyun Choe , Wan Beom Park , Hong Bin Kim , Myoung-Don Oh , Han Song , Sugyeong Kim , Minal Patel , Andriy Derkach , Erika Gedvilaite , Kaitlyn A Tkachuk , Brian J Wiley , Ireaneus C Chan , Lior Z Braunstein , Teng Gao , Elli Papaemmanuil , N Esther Babady , Melissa S Pessin , Mini Kamboj , Luis A Diaz , Marc Ladanyi , Michael J Rauh , Pradeep Natarajan , Mitchell J Machiela , Philip Awadalla , Vijai Joseph , Kenneth Offit , Larry Norton , Michael F Berger , Ross L Levine , Eu Suk Kim , Nam Joong Kim , Ahmet Zehir

Recurrent Mutations in Cyclin D3 Confer Clinical Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Catherine C Smith , Aaron D Viny , Evan Massi , Cyriac Kandoth , Nicholas D Socci , Franck Rapaport , Matthieu Najm , Juan S Medina-Martinez , Elli Papaemmanuil , Theodore C Tarver , Henry H Hsu , Mai H Le , Brian West , Gideon Bollag , Barry S Taylor , Ross L Levine , Neil P Shah

Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Barbara Spitzer , Kayleigh D Rutherford , Gunes Gundem , Erin M McGovern , Nathan E Millard , Juan E Arango Ossa , Irene Y Cheung , Teng Gao , Max F Levine , Yanming Zhang , Juan S Medina-Martínez , Yi Feng , Ryan N Ptashkin , Kelly L Bolton , Noushin Farnoud , Yangyu Zhou , Minal A Patel , Georgios Asimomitis , Cassidy C Cobbs , Neeman Mohibullah , Kety H Huberman , Maria E Arcilla , Brian H Kushner , Shakeel Modak , Andrew L Kung , Ahmet Zehir , Ross L Levine , Scott A Armstrong , Nai Kong V Cheung , Elli Papaemmanuil

Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers.

Nature communications

Avec: N Shukla , M F Levine , G Gundem , D Domenico , B Spitzer , N Bouvier , J E Arango-Ossa , D Glodzik , J S Medina-Martínez , U Bhanot , J Gutiérrez-Abril , Y Zhou , E Fiala , E Stockfisch , S Li , M I Rodriguez-Sanchez , T O'Donohue , C Cobbs , M H A Roehrl , J Benhamida , F Iglesias Cardenas , M Ortiz , M Kinnaman , S Roberts , M Ladanyi , S Modak , S Farouk-Sait , E Slotkin , M A Karajannis , F Dela Cruz , J Glade Bender , A Zehir , A Viale , M F Walsh , A L Kung ,

Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Kelly L Bolton , Denise Chen , Rosario Corona de la Fuente , Zhuxuan Fu , Rajmohan Murali , Martin Köbel , Yanis Tazi , Julie M Cunningham , Irenaeus C C Chan , Brian J Wiley , Lea A Moukarzel , Stacey J Winham , Sebastian M Armasu , Jenny Lester , Esther Elishaev , Angela Laslavic , Catherine J Kennedy , Anna Piskorz , Magdalena Sekowska , Alison H Brand , Yoke-Eng Chiew , Paul Pharoah , Kevin M Elias , Ronny Drapkin , Michael Churchman , Charlie Gourley , Anna DeFazio , Beth Karlan , James D Brenton , Britta Weigelt , Michael S Anglesio , David Huntsman , Simon Gayther , Jason Konner , Francesmary Modugno , Kate Lawrenson , Ellen L Goode , Elli Papaemmanuil

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy.

Blood

Avec: Annatina S Schnegg-Kaufmann , Julie A I Thoms , Golam Sarower Bhuyan , Henry R Hampton , Lachlin Vaughan , Kayleigh Rutherford , Purvi M Kakadia , Hui Mei Lee , Emma M V Johansson , Timothy W Failes , Greg M Arndt , Jason Koval , Robert Lindeman , Pauline Warburton , Alba Rodriguez-Meira , Adam J Mead , Ashwin Unnikrishnan , Sarah Davidson , Mark N Polizzotto , Mark Hertzberg , Elli Papaemmanuil , Stefan K Bohlander , Omid R Faridani , Christopher J Jolly , Fabio Zanini , John E Pimanda

Subclonal somatic copy number alterations emerge and dominate in recurrent osteosarcoma.

bioRxiv : the preprint server for biology

Avec: Michael D Kinnaman , Simone Zaccaria , Alvin Makohon-Moore , Brian Arnold , Max Levine , Gunes Gundem , Juan E Arango Ossa , Dominik Glodzik , M Irene Rodríguez-Sánchez , Nancy Bouvier , Shanita Li , Emily Stockfisch , Marisa Dunigan , Cassidy Cobbs , Umesh Bhanot , Daoqi You , Katelyn Mullen , Jerry Melchor , Michael V Ortiz , Tara O'Donohue , Emily Slotkin , Leonard H Wexler , Filemon S Dela Cruz , Meera Hameed , Julia L Glade Bender , William D Tap , Paul A Meyers , Elli Papaemmanuil , Andrew L Kung , Christine A Iacobuzio-Donahue

Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors.

JCO precision oncology

Avec: Sebastià Franch-Expósito , Miika Mehine , Ryan N Ptashkin , Kelly L Bolton , Chaitanya Bandlamudi , Preethi Srinivasan , Linda Zhang , Margaret A Goodell , Erika Gedvilaite , Kamal Menghrajani , Pablo Sánchez-Vela , Diana Mandelker , Elizabeth Comen , Larry Norton , Ryma Benayed , Teng Gao , Elli Papaemmanuil , Barry Taylor , Ross Levine , Kenneth Offit , Zsofia Stadler , Michael F Berger , Ahmet Zehir

Whole-Genome Sequencing Analysis of Male Breast Cancer Unveils Novel Structural Events and Potential Therapeutic Targets.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Avec: Majd Al Assaad , Olivier Michaud , Alissa Semaan , Michael Sigouros , Marvel Tranquille , Andy Phan , Max F Levine , Gunes Gundem , Juan S Medina-Martínez , Elli Papaemmanuil , Jyothi Manohar , David Wilkes , Andrea Sboner , Syed A F Hoda , Olivier Elemento , Juan Miguel Mosquera

Author Correction: The evolutionary history of lethal metastatic prostate cancer.

Nature

Avec: Gunes Gundem , Peter Van Loo , Barbara Kremeyer , Ludmil B Alexandrov , Jose M C Tubio , Elli Papaemmanuil , Daniel S Brewer , Heini M L Kallio , Gunilla Hägnäs , Matti Annala , Kati Kivinummi , Victoria Goody , Calli Latimer , Sarah O'Meara , Kevin J Dawson , William Isaacs , Michael R Emmert-Buck , Matti Nykter , Christopher Foster , Zsofia Kote-Jarai , Douglas Easton , Hayley C Whitaker , Auteur inconnu , David E Neal , Colin S Cooper , Rosalind A Eeles , Tapio Visakorpi , Peter J Campbell , Ultan McDermott , David C Wedge , G Steven Bova

Correction: Comprehensive detection of recurring genomic abnormalities: a targeted sequencing approach for multiple myeloma.

Blood cancer journal

The clinical implications of clonal hematopoiesis in hematopoietic cell transplantation.

Blood reviews

Avec: Mariam T Nawas , Johannes Schetelig , Frederik Damm , Ross L Levine , Miguel-Angel Perales , Sergio A Giralt , Marcel R VanDenBrink , Maria E Arcila , Ahmet Zehir , Elli Papaemmanuil , Anja Klussmeier , Alexander H Schmidt , Stephanie Maiwald , Kelly L Bolton , Roni Tamari

Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel

Cancer discovery

Avec: Emily K Slotkin , Daniel Diolaiti , Neerav N Shukla , Filemon S Dela Cruz , Jennifer J Clark , Gunes Gundem , Venkata D Yellapantula , Max F Levine , Daoqi You , Peilin Ma , Sagarika Pachhal , Glorymar Ibanez Sanchez , Ryma Benayed , Achim A Jungbluth , Lillian M Smyth , Audrey Mauguen , Irena Gushterova , Hongxu Ding , Lee Spraggon , Robert Darnell , Andrea Califano , Marc Ladanyi , Elli Papaemmanuil , Andrew L Kung , David M Hyman , Stephen S Roberts

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.

Leukemia

Avec: Detlef Haase , Kristen E Stevenson , Donna Neuberg , Jaroslaw P Maciejewski , Aziz Nazha , Mikkael A Sekeres , Benjamin L Ebert , Guillermo Garcia-Manero , Claudia Haferlach , Torsten Haferlach , Wolfgang Kern , Seishi Ogawa , Yasunobu Nagata , Kenichi Yoshida , Timothy A Graubert , Matthew J Walter , Alan F List , Rami S Komrokji , Eric Padron , David Sallman , Elli Papaemmanuil , Peter J Campbell , Michael R Savona , Adam Seegmiller , Lionel Adès , Pierre Fenaux , Lee-Yung Shih , David Bowen , Michael J Groves , Sudhir Tauro , Michaela Fontenay , Olivier Kosmider , Michal Bar-Natan , David Steensma , Richard Stone , Michael Heuser , Felicitas Thol , Mario Cazzola , Luca Malcovati , Aly Karsan , Christina Ganster , Eva Hellström-Lindberg , Jacqueline Boultwood , Andrea Pellagatti , Valeria Santini , Lynn Quek , Paresh Vyas , Heinz Tüchler , Peter L Greenberg , Rafael Bejar , Auteur inconnu

Genetic and genomic analysis of acute lymphoblastic leukemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials.

Haematologica

Avec: Thomas Creasey , Emilio Barretta , Sarra L Ryan , Ellie Butler , Amy A Kirkwood , Daniel Leongamornlert , Elli Papaemmanuil , Pip Patrick , Laura Clifton-Hadley , Bela Patel , Tobias Menne , Andrew K McMillan , Christine J Harrison , Clare J Rowntree , Nick Morley , David I Marks , Adele K Fielding , Anthony V Moorman

DNA Methylation Profiles of Ovarian Clear Cell Carcinoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Avec: Julie M Cunningham , Stacey J Winham , Chen Wang , Britta Weiglt , Zhuxuan Fu , Sebastian M Armasu , Bryan M McCauley , Alison H Brand , Yoke-Eng Chiew , Esther Elishaev , Charlie Gourley , Catherine J Kennedy , Angela Laslavic , Jenny Lester , Anna Piskorz , Magdalena Sekowska , James D Brenton , Michael Churchman , Anna DeFazio , Ronny Drapkin , Kevin M Elias , David G Huntsman , Beth Y Karlan , Martin Köbel , Jason Konner , Kate Lawrenson , Elli Papaemmanuil , Kelly L Bolton , Francesmary Modugno , Ellen L Goode

Cancer therapy shapes the fitness landscape of clonal hematopoiesis.

Nature genetics

Avec: Kelly L Bolton , Ryan N Ptashkin , Teng Gao , Lior Braunstein , Sean M Devlin , Daniel Kelly , Minal Patel , Antonin Berthon , Aijazuddin Syed , Mariko Yabe , Catherine C Coombs , Nicole M Caltabellotta , Mike Walsh , Kenneth Offit , Zsofia Stadler , Diana Mandelker , Jessica Schulman , Akshar Patel , John Philip , Elsa Bernard , Gunes Gundem , Juan E Arango Ossa , Max Levine , Juan S Medina Martinez , Noushin Farnoud , Dominik Glodzik , Sonya Li , Mark E Robson , Choonsik Lee , Paul D P Pharoah , Konrad H Stopsack , Barbara Spitzer , Simon Mantha , James Fagin , Laura Boucai , Christopher J Gibson , Benjamin L Ebert , Andrew L Young , Todd Druley , Koichi Takahashi , Nancy Gillis , Markus Ball , Eric Padron , David M Hyman , Jose Baselga , Larry Norton , Stuart Gardos , Virginia M Klimek , Howard Scher , Dean Bajorin , Eder Paraiso , Ryma Benayed , Maria E Arcila , Marc Ladanyi , David B Solit , Michael F Berger , Martin Tallman , Montserrat Garcia-Closas , Nilanjan Chatterjee , Luis A Diaz , Ross L Levine , Lindsay M Morton , Ahmet Zehir , Elli Papaemmanuil

IKZF1 alterations are not associated with outcome in 498 adults with B-precursor ALL enrolled in the UKALL14 trial.

Blood advances

Avec: Rachel J Mitchell , Amy A Kirkwood , Emilio Barretta , Laura Clifton-Hadley , Emma Lawrie , SooWah Lee , Daniel Leongamornlert , David I Marks , Andrew K McMillan , Tobias F Menne , Elli Papaemmanuil , Bela Patel , Pip Patrick , Clare J Rowntree , Nahid Zareian , Krisztina Zuborne Alapi , Anthony V Moorman , Adele K Fielding

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelomonocytic Leukemia: Clinical and Molecular Genetic Prognostic Factors in a Nordic Population.

Transplantation and cellular therapy

Avec: Eileen Wedge , Jakob Werner Hansen , Ingunn Dybedal , Maria Creignou , Elisabeth Ejerblad , Fryderyk Lorenz , Olle Werlenius , Johanna Ungerstedt , Mette Skov Holm , Lars Nilsson , Astrid Olsnes Kittang , Peter Antunovic , Peter Rohon , Mette Klarskov Andersen , Elli Papaemmanuil , Elsa Bernard , Martin Jädersten , Eva Hellström-Lindberg , Kirsten Grønbæk , Per Ljungman , Lone Smidstrup Friis

PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum.

Acta neuropathologica

Avec: Karam T Alhalabi , Damian Stichel , Philipp Sievers , Heike Peterziel , Alexander C Sommerkamp , Dominik Sturm , Andrea Wittmann , Martin Sill , Natalie Jäger , Pengbo Beck , Kristian W Pajtler , Matija Snuderl , George Jour , Michael Delorenzo , Allison M Martin , Adam Levy , Nagma Dalvi , Jordan R Hansford , Nicholas G Gottardo , Emmanuelle Uro-Coste , Claude-Alain Maurage , Catherine Godfraind , Fanny Vandenbos , Torsten Pietsch , Christof Kramm , Maria Filippidou , Antonis Kattamis , Chris Jones , Ingrid Øra , Torben Stamm Mikkelsen , Michal Zapotocky , David Sumerauer , David Scheie , Martin McCabe , Pieter Wesseling , Bastiaan B J Tops , Mariëtte E G Kranendonk , Matthias A Karajannis , Nancy Bouvier , Elli Papaemmanuil , Hildegard Dohmen , Till Acker , Katja von Hoff , Simone Schmid , Evelina Miele , Katharina Filipski , Lidija Kitanovski , Lenka Krskova , Johannes Gojo , Christine Haberler , Frank Alvaro , Jonas Ecker , Florian Selt , Till Milde , Olaf Witt , Ina Oehme , Marcel Kool , Andreas von Deimling , Andrey Korshunov , Stefan M Pfister , Felix Sahm , David T W Jones

Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma.

Cancer research

Avec: Michael D Kinnaman , Simone Zaccaria , Alvin Makohon-Moore , Brian Arnold , Max F Levine , Gunes Gundem , Juan E Arango Ossa , Dominik Glodzik , M Irene Rodríguez-Sánchez , Nancy Bouvier , Shanita Li , Emily Stockfisch , Marisa Dunigan , Cassidy Cobbs , Umesh K Bhanot , Daoqi You , Katelyn Mullen , Jerry P Melchor , Michael V Ortiz , Tara J O'Donohue , Emily K Slotkin , Leonard H Wexler , Filemon S Dela Cruz , Meera R Hameed , Julia L Glade Bender , William D Tap , Paul A Meyers , Elli Papaemmanuil , Andrew L Kung , Christine A Iacobuzio-Donahue

Unified classification and risk-stratification in Acute Myeloid Leukemia.

Nature communications

Avec: Yanis Tazi , Juan E Arango-Ossa , Yangyu Zhou , Elsa Bernard , Ian Thomas , Amanda Gilkes , Sylvie Freeman , Yoann Pradat , Sean J Johnson , Robert Hills , Richard Dillon , Max F Levine , Daniel Leongamornlert , Adam Butler , Arnold Ganser , Lars Bullinger , Konstanze Döhner , Oliver Ottmann , Richard Adams , Hartmut Döhner , Peter J Campbell , Alan K Burnett , Michael Dennis , Nigel H Russell , Sean M Devlin , Brian J P Huntly , Elli Papaemmanuil

Molecular predictors of immunophenotypic measurable residual disease clearance in acute myeloid leukemia.

American journal of hematology

Avec: Maximilian Stahl , Andriy Derkach , Noushin Farnoud , Jan Philipp Bewersdorf , Troy Robinson , Christopher Famulare , Christina Cho , Sean Devlin , Kamal Menghrajani , Minal A Patel , Sheng F Cai , Linde A Miles , Robert L Bowman , Mark B Geyer , Andrew Dunbar , Zachary D Epstein-Peterson , Erin McGovern , Jessica Schulman , Jacob L Glass , Justin Taylor , Aaron D Viny , Eytan M Stein , Bartlomiej Getta , Maria E Arcila , Qi Gao , Juliet Barker , Brian C Shaffer , Esperanza B Papadopoulos , Boglarka Gyurkocza , Miguel-Angel Perales , Omar Abdel-Wahab , Ross L Levine , Sergio A Giralt , Yanming Zhang , Wenbin Xiao , Nidhi Pai , Elli Papaemmanuil , Martin S Tallman , Mikhail Roshal , Aaron D Goldberg

Early transfusion patterns improve the Molecular International Prognostic Scoring System (IPSS-M) prediction in myelodysplastic syndromes.

Journal of internal medicine

Avec: Maria Creignou , Elsa Bernard , Alessandro Gasparini , Anna Tranberg , Gabriele Todisco , Pedro Luis Moura , Elisabeth Ejerblad , Lars Nilsson , Hege Garelius , Petar Antunovic , Fryderyk Lorenz , Bengt Rasmussen , Gunilla Walldin , Teresa Mortera-Blanco , Monika Jansson , Magnus Tobiasson , Chiara Elena , Jacqueline Ferrari , Anna Gallì , Sara Pozzi , Luca Malcovati , Gustaf Edgren , Michael J Crowther , Martin Jädersten , Elli Papaemmanuil , Eva Hellström-Lindberg

Molecular, clinical and therapeutic determinants of outcome in NPM1 mutated AML.

Blood

Avec: Jad Othman , Nicola Potter , Adam Ivey , Yanis Tazi , Elli Papaemmanuil , Jelena Jovanovic , Sylvie D Freeman , Amanda Frances Gilkes , Rosemary E Gale , Tanya Rapoz-D'Silva , Manohursingh Runglall , Michelle Kleeman , Pawan Dhami , Ian Thomas , Sean Johnson , Joanna Canham , James Durrell Cavenagh , Panagiotis Kottaridis , Claire Arnold , Hans Beier Ommen , Ulrik Malthe Overgaard , Mike Dennis , Alan Kenneth Burnett , Charlotte S Wilhelm-Benartzi , Brian Jp Huntly , Nigel H Russell , Richard James Dillon

RAS-mutant leukaemia stem cells drive clinical resistance to venetoclax.

Nature

Avec: Junya Sango , Saul Carcamo , Maria Sirenko , Abhishek Maiti , Hager Mansour , Gulay Ulukaya , Lewis E Tomalin , Nataly Cruz-Rodriguez , Tiansu Wang , Malgorzata Olszewska , Emmanuel Olivier , Manon Jaud , Bettina Nadorp , Benjamin Kroger , Feng Hu , Lewis Silverman , Stephen S Chung , Elvin Wagenblast , Ronan Chaligne , Ann-Kathrin Eisfeld , Deniz Demircioglu , Dan A Landau , Piro Lito , Elli Papaemmanuil , Courtney D DiNardo , Dan Hasson , Marina Konopleva , Eirini P Papapetrou

Réseau de co-auteurs

Elli Papaemmanuil 69 collaborations

Gunes Gundem 19 collaborations

Elsa Bernard 16 collaborations

Luca Malcovati 12 collaborations

Max F Levine 12 collaborations

Kelly L Bolton 12 collaborations

Yanming Zhang 11 collaborations

Ola Landgren 11 collaborations

Minal Patel 10 collaborations

Benjamin L Ebert 10 collaborations

Seishi Ogawa 10 collaborations

Ross L Levine 10 collaborations

Mario Cazzola 9 collaborations

Eva Hellström-Lindberg 9 collaborations

Ahmet Zehir 9 collaborations

Even H Rustad 9 collaborations

Francesco Maura 9 collaborations

Maria Creignou 8 collaborations

Malin Hultcrantz 8 collaborations

Michael R Savona 7 collaborations

Rafael Bejar 7 collaborations

Daniel Leongamornlert 7 collaborations

Peter J Campbell 7 collaborations

Venkata Yellapantula 7 collaborations

Maria E Arcila 7 collaborations

Andrew L Kung 7 collaborations

Robert P Hasserjian 6 collaborations

Sean M Devlin 6 collaborations

Yangyu Zhou 6 collaborations

Martin Jädersten 6 collaborations

Magnus Tobiasson 6 collaborations

Ioannis Kotsianidis 6 collaborations

Jacqueline Boultwood 6 collaborations

Pierre Fenaux 6 collaborations

Andrea Pellagatti 6 collaborations

Michael Heuser 6 collaborations

Michaela Fontenay 6 collaborations

Peter L Greenberg 6 collaborations

Michael F Berger 6 collaborations

Noushin Farnoud 6 collaborations

Ahmet Dogan 6 collaborations

Theresia Akhlaghi 6 collaborations

Sham Mailankody 6 collaborations

Juan E Arango Ossa 6 collaborations

Andriy Derkach 6 collaborations

Teng Gao 6 collaborations

Nancy Bouvier 6 collaborations

Olivier Kosmider 5 collaborations

Valeria Santini 5 collaborations

Christina Ganster 5 collaborations

Joop H Jansen 5 collaborations

Venkata D Yellapantula 5 collaborations

Dominik Glodzik 5 collaborations

Juan S Medina-Martínez 5 collaborations

Marc Ladanyi 5 collaborations

Kenneth Offit 5 collaborations

Daoqi You 5 collaborations

Hartmut Döhner 4 collaborations

Peter Campbell 4 collaborations

Yasuhito Nannya 4 collaborations

Juan S Medina-Martinez 4 collaborations

Detlef Haase 4 collaborations

Ulrich Germing 4 collaborations

Matilde Y Follo 4 collaborations

Felicitas Thol 4 collaborations

Fabio P S Santos 4 collaborations

Monika Belickova 4 collaborations

Laura Palomo 4 collaborations

Matteo Giovanni Della Porta 4 collaborations

Kamal Menghrajani 4 collaborations

Uwe Platzbecker 4 collaborations

Peter Valent 4 collaborations

Carlo Finelli 4 collaborations

Maria Teresa Voso 4 collaborations

José Cervera 4 collaborations

Norbert Gattermann 4 collaborations

Ryan N Ptashkin 4 collaborations

Kylee H Maclachlan 4 collaborations

Paresh Vyas 4 collaborations

Juan Esteban Arango Ossa 4 collaborations

Maria Sirenko 4 collaborations

Mikhail Roshal 4 collaborations

Juan E Arango-Ossa 4 collaborations

Christine A Iacobuzio-Donahue 4 collaborations

Luis A Diaz 4 collaborations

Larry Norton 4 collaborations

None None 4 collaborations

Shakeel Modak 4 collaborations

Anthony V Moorman 4 collaborations

Emilio Barretta 4 collaborations

Amy A Kirkwood 4 collaborations

Pip Patrick 4 collaborations

Laura Clifton-Hadley 4 collaborations

Bela Patel 4 collaborations

Adele K Fielding 4 collaborations

Barbara Spitzer 4 collaborations

Ryma Benayed 4 collaborations

Robert Hills 3 collaborations

Brian J P Huntly 3 collaborations

Heinz Tuechler 3 collaborations

Francesc Solé 3 collaborations

Arjan A van de Loosdrecht 3 collaborations

Virginia M Klimek 3 collaborations

Lionel Ades 3 collaborations

Lee-Yung Shih 3 collaborations

Alessandro M Vannucchi 3 collaborations

Benjamin Diamond 3 collaborations

Niccolò Bolli 3 collaborations

Neha Korde 3 collaborations

Heather J Landau 3 collaborations

David J Chung 3 collaborations

Dylan Domenico 3 collaborations

Lurdes Zamora 3 collaborations

Courtney D DiNardo 3 collaborations

Lucy A Godley 3 collaborations

Martin S Tallman 3 collaborations

Majd Al Assaad 3 collaborations

Andrea Sboner 3 collaborations

Juan Miguel Mosquera 3 collaborations

Juan Santiago Medina-Martinez 3 collaborations

Max Fine Levine 3 collaborations

Virginia Klimek 3 collaborations

Juan Arango Ossa 3 collaborations

Alvin Makohon-Moore 3 collaborations

Caleb Ho 3 collaborations

Georgios Asimomitis 3 collaborations

Teresa Mortera-Blanco 3 collaborations

Bachisio Ziccheddu 3 collaborations

Gabriele Todisco 3 collaborations

Heather Landau 3 collaborations

Mikkael A Sekeres 3 collaborations

Ryan Ptashkin 3 collaborations

Erika Gedvilaite 3 collaborations

Lior Z Braunstein 3 collaborations

Vijai Joseph 3 collaborations

Michael V Ortiz 3 collaborations

Neerav Shukla 3 collaborations

Zsofia Stadler 3 collaborations

Brian H Kushner 3 collaborations

Stephen S Roberts 3 collaborations

Andrew K McMillan 3 collaborations

Christine J Harrison 3 collaborations

Clare J Rowntree 3 collaborations

David I Marks 3 collaborations

Guillermo Garcia-Manero 3 collaborations

Torsten Haferlach 3 collaborations

Matthew J Walter 3 collaborations

David B Solit 3 collaborations

Aaron D Viny 3 collaborations

Max Levine 3 collaborations

Emily K Slotkin 3 collaborations

William D Tap 3 collaborations

Leonard H Wexler 3 collaborations

Paul A Meyers 3 collaborations

Yanis Tazi 3 collaborations

Filemon S Dela Cruz 3 collaborations

George Giotopoulos 2 collaborations

Haiyang Yun 2 collaborations

Daniel Sasca 2 collaborations

Paolo Gallipoli 2 collaborations

Lars Bullinger 2 collaborations

Richard Dillon 2 collaborations

Sylvie Freeman 2 collaborations

Oliver Ottmann 2 collaborations

Nigel Russell 2 collaborations

Tetsuichi Yoshizato 2 collaborations

Catherine A Cargo 2 collaborations

Ronald F Pinheiro 2 collaborations

Senji Kasahara 2 collaborations

Takayuki Ishikawa 2 collaborations

Akifumi Takaori-Kondo 2 collaborations

Guillermo Sanz 2 collaborations

Harold K Elias 2 collaborations

Donna S Neuberg 2 collaborations

Kristen E Stevenson 2 collaborations

Shigeru Chiba 2 collaborations

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