Ryan N Ptashkin

Affiliations

C2i Genomics, United States.

Publications (14)

High risk and silent clonal hematopoietic genotypes in patients with non-hematologic cancer.

Blood advances

Avec: Aaron James Stonestrom , Kamal N Menghrajani , Sean M Devlin , Sebastià Franch-Expósito , Ryan N Ptashkin , Swara Y Patel , Barbara Spitzer , Xiaodi Wu , Justin Jee , Pablo Sánchez Vela , Jennifer Milbank , Ronak H Shah , Abhinita S Mohanty , Rose Rose Brannon , Wenbin Xiao , Michael F Berger , Simon Mantha , Ross L Levine

Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing.

Nature communications

Avec: Ryan N Ptashkin , Mark D Ewalt , Gowtham Jayakumaran , Iwona Kiecka , Anita S Bowman , JinJuan Yao , Jacklyn Casanova , Yun-Te David Lin , Kseniya Petrova-Drus , Abhinita S Mohanty , Ruben Bacares , Jamal Benhamida , Satshil Rana , Anna Razumova , Chad Vanderbilt , Anoop Balakrishnan Rema , Ivelise Rijo , Julie Son-Garcia , Ino de Bruijn , Menglei Zhu , Sean Lachhander , Wei Wang , Mohammad S Haque , Venkatraman E Seshan , Jiajing Wang , Ying Liu , Khedoudja Nafa , Laetitia Borsu , Yanming Zhang , Umut Aypar , Sarah P Suehnholz , Debyani Chakravarty , Jae H Park , Omar Abdel-Wahab , Anthony R Mato , Wenbin Xiao , Mikhail Roshal , Mariko Yabe , Connie Lee Batlevi , Sergio Giralt , Gilles Salles , Raajit Rampal , Martin Tallman , Eytan M Stein , Anas Younes , Ross L Levine , Miguel-Angel Perales , Marcel R M van den Brink , Ahmet Dogan , Marc Ladanyi , Michael F Berger , A Rose Brannon , Ryma Benayed , Ahmet Zehir , Maria E Arcila

Cancer therapy shapes the fitness landscape of clonal hematopoiesis.

Nature genetics

Avec: Kelly L Bolton , Ryan N Ptashkin , Teng Gao , Lior Braunstein , Sean M Devlin , Daniel Kelly , Minal Patel , Antonin Berthon , Aijazuddin Syed , Mariko Yabe , Catherine C Coombs , Nicole M Caltabellotta , Mike Walsh , Kenneth Offit , Zsofia Stadler , Diana Mandelker , Jessica Schulman , Akshar Patel , John Philip , Elsa Bernard , Gunes Gundem , Juan E Arango Ossa , Max Levine , Juan S Medina Martinez , Noushin Farnoud , Dominik Glodzik , Sonya Li , Mark E Robson , Choonsik Lee , Paul D P Pharoah , Konrad H Stopsack , Barbara Spitzer , Simon Mantha , James Fagin , Laura Boucai , Christopher J Gibson , Benjamin L Ebert , Andrew L Young , Todd Druley , Koichi Takahashi , Nancy Gillis , Markus Ball , Eric Padron , David M Hyman , Jose Baselga , Larry Norton , Stuart Gardos , Virginia M Klimek , Howard Scher , Dean Bajorin , Eder Paraiso , Ryma Benayed , Maria E Arcila , Marc Ladanyi , David B Solit , Michael F Berger , Martin Tallman , Montserrat Garcia-Closas , Nilanjan Chatterjee , Luis A Diaz , Ross L Levine , Lindsay M Morton , Ahmet Zehir , Elli Papaemmanuil

Genetic basis of SMARCB1 protein loss in 22 sinonasal carcinomas.

Human pathology

Avec: Snjezana Dogan , Paolo Cotzia , Ryan N Ptashkin , Gouri J Nanjangud , Bin Xu , Amir Momeni Boroujeni , Marc A Cohen , David G Pfister , Manju L Prasad , Cristina R Antonescu , Yingbei Chen , Mrinal M Gounder

The Clinical Management of Clonal Hematopoiesis: Creation of a Clonal Hematopoiesis Clinic.

Hematology/oncology clinics of North America

Avec: Kelly L Bolton , Ahmet Zehir , Ryan N Ptashkin , Minal Patel , Dipti Gupta , Robert Sidlow , Elli Papaemmanuil , Michael F Berger , Ross L Levine

Effects of radioactive iodine on clonal hematopoiesis in patients with thyroid cancer: A prospective study.

Clinical endocrinology

Avec: Laura Boucai , Ryan N Ptashkin , Ross L Levine , James A Fagin

Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies.

Haematologica

Avec: Melissa Krystel-Whittemore , Kseniya Petrova-Drus , Ryan N Ptashkin , Mark D Ewalt , JinJuan Yao , Ying Liu , Menglei Zhu , Jamal Benhamida , Benjamin Durham , Jyoti Kumar , Khedoudja Nafa , Iwona Kiecka , Anita S Bowman , Erika Gedvilaite , Jacklyn Casanova , Yun-Te Lin , Abhinita S Mohanty , Satshil Rana , Anoop Balakrishnan Rema , Ivelise Rijo , Nelio Chaves , Paulo Salazar , Anita Yun , Sean Lachhander , Wei Wang , Mohammad S Haque , Wenbin Xiao , Mikhail Roshal , Sergio Giralt , Gilles Salles , Raajit Rampal , Eytan M Stein , Miguel-Angel Perales , Steven Horwitz , Ann Jakubowski , Doris Ponce , Alina Markova , Ozge Birsoy , Diana Mandelker , Simon Mantha , Ahmet Dogan , Ryma Benayed , Marc Ladanyi , Michael F Berger , A Rose Brannon , Ahmet Zehir , Chad Vanderbilt , Maria E Arcila

Cancer-Causative Mutations Occurring in Early Embryogenesis.

Cancer discovery

Avec: Fresia Pareja , Ryan N Ptashkin , David N Brown , Fatemeh Derakhshan , Pier Selenica , Edaise M da Silva , Andrea M Gazzo , Arnaud Da Cruz Paula , Kelsey Breen , Ronglai Shen , Antonio Marra , Ahmet Zehir , Ryma Benayed , Michael F Berger , Ozge Ceyhan-Birsoy , Sowmya Jairam , Margaret Sheehan , Utsav Patel , Yelena Kemel , Jacklyn Casanova-Murphy , Christopher J Schwartz , Mahsa Vahdatinia , Elizabeth Comen , Laetitia Borsu , Xin Pei , Nadeem Riaz , David H Abramson , Britta Weigelt , Michael F Walsh , Anna-Katerina Hadjantonakis , Marc Ladanyi , Kenneth Offit , Zsofia K Stadler , Mark E Robson , Jorge S Reis-Filho , Diana Mandelker

Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Barbara Spitzer , Kayleigh D Rutherford , Gunes Gundem , Erin M McGovern , Nathan E Millard , Juan E Arango Ossa , Irene Y Cheung , Teng Gao , Max F Levine , Yanming Zhang , Juan S Medina-Martínez , Yi Feng , Ryan N Ptashkin , Kelly L Bolton , Noushin Farnoud , Yangyu Zhou , Minal A Patel , Georgios Asimomitis , Cassidy C Cobbs , Neeman Mohibullah , Kety H Huberman , Maria E Arcilla , Brian H Kushner , Shakeel Modak , Andrew L Kung , Ahmet Zehir , Ross L Levine , Scott A Armstrong , Nai Kong V Cheung , Elli Papaemmanuil

Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors.

JCO precision oncology

Avec: Sebastià Franch-Expósito , Miika Mehine , Ryan N Ptashkin , Kelly L Bolton , Chaitanya Bandlamudi , Preethi Srinivasan , Linda Zhang , Margaret A Goodell , Erika Gedvilaite , Kamal Menghrajani , Pablo Sánchez-Vela , Diana Mandelker , Elizabeth Comen , Larry Norton , Ryma Benayed , Teng Gao , Elli Papaemmanuil , Barry Taylor , Ross Levine , Kenneth Offit , Zsofia Stadler , Michael F Berger , Ahmet Zehir

DNA methylation-based classification of sinonasal undifferentiated carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Avec: Snjezana Dogan , Varshini Vasudevaraja , Bin Xu , Jonathan Serrano , Ryan N Ptashkin , Hun Jae Jung , Sarah Chiang , Achim A Jungbluth , Marc A Cohen , Ian Ganly , Michael F Berger , Amir Momeni Boroujeni , Ronald A Ghossein , Marc Ladanyi , Deborah J Chute , Matija Snuderl

SMARCA4-Deficient Thoracic Sarcomatoid Tumors Represent Primarily Smoking-Related Undifferentiated Carcinomas Rather Than Primary Thoracic Sarcomas.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Natasha Rekhtman , Joseph Montecalvo , Jason C Chang , Deepu Alex , Ryan N Ptashkin , Ni Ai , Jennifer L Sauter , Brie Kezlarian , Achim Jungbluth , Patrice Desmeules , Amanda Beras , Justin A Bishop , Andrew J Plodkowski , Mrinal M Gounder , Adam J Schoenfeld , Azadeh Namakydoust , Bob T Li , Charles M Rudin , Gregory J Riely , David R Jones , Marc Ladanyi , William D Travis

First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial.

The Lancet. Oncology

Avec: Yelena Y Janjigian , Steven B Maron , Walid K Chatila , Brittanie Millang , Shweta S Chavan , Carly Alterman , Joanne F Chou , Michal F Segal , Marc Z Simmons , Parisa Momtaz , Marina Shcherba , Geoffrey Y Ku , Alice Zervoudakis , Elizabeth S Won , David P Kelsen , David H Ilson , Rebecca J Nagy , Richard B Lanman , Ryan N Ptashkin , Mark T A Donoghue , Marinela Capanu , Barry S Taylor , David B Solit , Nikolaus Schultz , Jaclyn F Hechtman

Bioinformatically Expanded Next-Generation Sequencing Analysis Optimizes Identification of Therapeutically Relevant MET Copy Number Alterations in >50,000 Tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: James P Solomon , Soo-Ryum Yang , Noura J Choudhury , Ryan N Ptashkin , Nasrin Eslamdoost , Christina J Falcon , Axel Martin , Andrew Plodkowski , Clare Wilhelm , Ronglai Shen , Marc Ladanyi , Michael Berger , Yanming Zhang , Alexander Drilon , Maria E Arcila

Réseau de co-auteurs

Michael F Berger 8 collaborations

Marc Ladanyi 7 collaborations

Ahmet Zehir 7 collaborations

Ross L Levine 6 collaborations

Ryma Benayed 5 collaborations

Maria E Arcila 4 collaborations

Kelly L Bolton 4 collaborations

Diana Mandelker 4 collaborations

Elli Papaemmanuil 4 collaborations

Barbara Spitzer 3 collaborations

Abhinita S Mohanty 3 collaborations

Wenbin Xiao 3 collaborations

Simon Mantha 3 collaborations

Yanming Zhang 3 collaborations

Teng Gao 3 collaborations

Kenneth Offit 3 collaborations

Sean M Devlin 2 collaborations

Sebastià Franch-Expósito 2 collaborations

Mark D Ewalt 2 collaborations

Iwona Kiecka 2 collaborations

Anita S Bowman 2 collaborations

JinJuan Yao 2 collaborations

Jacklyn Casanova 2 collaborations

Kseniya Petrova-Drus 2 collaborations

Jamal Benhamida 2 collaborations

Satshil Rana 2 collaborations

Chad Vanderbilt 2 collaborations

Anoop Balakrishnan Rema 2 collaborations

Ivelise Rijo 2 collaborations

Menglei Zhu 2 collaborations

Sean Lachhander 2 collaborations

Wei Wang 2 collaborations

Mohammad S Haque 2 collaborations

Ying Liu 2 collaborations

Khedoudja Nafa 2 collaborations

Laetitia Borsu 2 collaborations

Mikhail Roshal 2 collaborations

Mariko Yabe 2 collaborations

Sergio Giralt 2 collaborations

Gilles Salles 2 collaborations

Raajit Rampal 2 collaborations

Martin Tallman 2 collaborations

Eytan M Stein 2 collaborations

Miguel-Angel Perales 2 collaborations

Ahmet Dogan 2 collaborations

A Rose Brannon 2 collaborations

Minal Patel 2 collaborations

Zsofia Stadler 2 collaborations

Gunes Gundem 2 collaborations

Juan E Arango Ossa 2 collaborations

Noushin Farnoud 2 collaborations

Mark E Robson 2 collaborations

Laura Boucai 2 collaborations

Larry Norton 2 collaborations

David B Solit 2 collaborations

Snjezana Dogan 2 collaborations

Bin Xu 2 collaborations

Amir Momeni Boroujeni 2 collaborations

Marc A Cohen 2 collaborations

Mrinal M Gounder 2 collaborations

Erika Gedvilaite 2 collaborations

Ronglai Shen 2 collaborations

Elizabeth Comen 2 collaborations

Aaron James Stonestrom 1 collaboration

Kamal N Menghrajani 1 collaboration

Swara Y Patel 1 collaboration

Xiaodi Wu 1 collaboration

Justin Jee 1 collaboration

Pablo Sánchez Vela 1 collaboration

Jennifer Milbank 1 collaboration

Ronak H Shah 1 collaboration

Rose Rose Brannon 1 collaboration

Gowtham Jayakumaran 1 collaboration

Yun-Te David Lin 1 collaboration

Ruben Bacares 1 collaboration

Anna Razumova 1 collaboration

Julie Son-Garcia 1 collaboration

Ino de Bruijn 1 collaboration

Venkatraman E Seshan 1 collaboration

Jiajing Wang 1 collaboration

Umut Aypar 1 collaboration

Sarah P Suehnholz 1 collaboration

Debyani Chakravarty 1 collaboration

Jae H Park 1 collaboration

Omar Abdel-Wahab 1 collaboration

Anthony R Mato 1 collaboration

Connie Lee Batlevi 1 collaboration

Anas Younes 1 collaboration

Marcel R M van den Brink 1 collaboration

Lior Braunstein 1 collaboration

Daniel Kelly 1 collaboration

Antonin Berthon 1 collaboration

Aijazuddin Syed 1 collaboration

Catherine C Coombs 1 collaboration

Nicole M Caltabellotta 1 collaboration

Mike Walsh 1 collaboration

Jessica Schulman 1 collaboration

Akshar Patel 1 collaboration

John Philip 1 collaboration

Elsa Bernard 1 collaboration

Max Levine 1 collaboration

Juan S Medina Martinez 1 collaboration

Dominik Glodzik 1 collaboration

Sonya Li 1 collaboration

Choonsik Lee 1 collaboration

Paul D P Pharoah 1 collaboration

Konrad H Stopsack 1 collaboration

James Fagin 1 collaboration

Christopher J Gibson 1 collaboration

Benjamin L Ebert 1 collaboration

Andrew L Young 1 collaboration

Todd Druley 1 collaboration

Koichi Takahashi 1 collaboration

Nancy Gillis 1 collaboration

Markus Ball 1 collaboration

Eric Padron 1 collaboration

David M Hyman 1 collaboration

Jose Baselga 1 collaboration

Stuart Gardos 1 collaboration

Virginia M Klimek 1 collaboration

Howard Scher 1 collaboration

Dean Bajorin 1 collaboration

Eder Paraiso 1 collaboration

Montserrat Garcia-Closas 1 collaboration

Nilanjan Chatterjee 1 collaboration

Luis A Diaz 1 collaboration

Lindsay M Morton 1 collaboration

Paolo Cotzia 1 collaboration

Gouri J Nanjangud 1 collaboration

David G Pfister 1 collaboration

Manju L Prasad 1 collaboration

Cristina R Antonescu 1 collaboration

Yingbei Chen 1 collaboration

Dipti Gupta 1 collaboration

Robert Sidlow 1 collaboration

James A Fagin 1 collaboration

Melissa Krystel-Whittemore 1 collaboration

Benjamin Durham 1 collaboration

Jyoti Kumar 1 collaboration

Yun-Te Lin 1 collaboration

Nelio Chaves 1 collaboration

Paulo Salazar 1 collaboration

Anita Yun 1 collaboration

Steven Horwitz 1 collaboration

Ann Jakubowski 1 collaboration

Doris Ponce 1 collaboration

Alina Markova 1 collaboration

Ozge Birsoy 1 collaboration

Fresia Pareja 1 collaboration

David N Brown 1 collaboration

Fatemeh Derakhshan 1 collaboration

Pier Selenica 1 collaboration

Edaise M da Silva 1 collaboration

Andrea M Gazzo 1 collaboration

Arnaud Da Cruz Paula 1 collaboration

Kelsey Breen 1 collaboration

Antonio Marra 1 collaboration

Ozge Ceyhan-Birsoy 1 collaboration

Sowmya Jairam 1 collaboration

Margaret Sheehan 1 collaboration

Utsav Patel 1 collaboration

Yelena Kemel 1 collaboration

Jacklyn Casanova-Murphy 1 collaboration

Christopher J Schwartz 1 collaboration

Mahsa Vahdatinia 1 collaboration

Xin Pei 1 collaboration

Nadeem Riaz 1 collaboration

David H Abramson 1 collaboration

Britta Weigelt 1 collaboration

Michael F Walsh 1 collaboration

Anna-Katerina Hadjantonakis 1 collaboration

Zsofia K Stadler 1 collaboration

Jorge S Reis-Filho 1 collaboration

Kayleigh D Rutherford 1 collaboration

Erin M McGovern 1 collaboration

Nathan E Millard 1 collaboration

Irene Y Cheung 1 collaboration

Max F Levine 1 collaboration

Juan S Medina-Martínez 1 collaboration

Yi Feng 1 collaboration

Yangyu Zhou 1 collaboration

Minal A Patel 1 collaboration

Georgios Asimomitis 1 collaboration

Cassidy C Cobbs 1 collaboration

Neeman Mohibullah 1 collaboration

Kety H Huberman 1 collaboration

Maria E Arcilla 1 collaboration

Brian H Kushner 1 collaboration

Shakeel Modak 1 collaboration

Andrew L Kung 1 collaboration

Scott A Armstrong 1 collaboration

Nai Kong V Cheung 1 collaboration

Miika Mehine 1 collaboration

Chaitanya Bandlamudi 1 collaboration

Preethi Srinivasan 1 collaboration

Linda Zhang 1 collaboration

Margaret A Goodell 1 collaboration

Kamal Menghrajani 1 collaboration

Pablo Sánchez-Vela 1 collaboration

Barry Taylor 1 collaboration

Ross Levine 1 collaboration

Varshini Vasudevaraja 1 collaboration

Jonathan Serrano 1 collaboration

Hun Jae Jung 1 collaboration

Sarah Chiang 1 collaboration

Achim A Jungbluth 1 collaboration

Ian Ganly 1 collaboration

Ronald A Ghossein 1 collaboration

Deborah J Chute 1 collaboration

Matija Snuderl 1 collaboration

Natasha Rekhtman 1 collaboration

Joseph Montecalvo 1 collaboration

Jason C Chang 1 collaboration

Deepu Alex 1 collaboration

Ni Ai 1 collaboration

Jennifer L Sauter 1 collaboration

Brie Kezlarian 1 collaboration

Achim Jungbluth 1 collaboration

Patrice Desmeules 1 collaboration

Amanda Beras 1 collaboration

Justin A Bishop 1 collaboration

Andrew J Plodkowski 1 collaboration

Adam J Schoenfeld 1 collaboration

Azadeh Namakydoust 1 collaboration

Bob T Li 1 collaboration

Charles M Rudin 1 collaboration

Gregory J Riely 1 collaboration

David R Jones 1 collaboration

William D Travis 1 collaboration

Yelena Y Janjigian 1 collaboration

Steven B Maron 1 collaboration

Walid K Chatila 1 collaboration

Brittanie Millang 1 collaboration

Shweta S Chavan 1 collaboration

Carly Alterman 1 collaboration

Joanne F Chou 1 collaboration

Michal F Segal 1 collaboration

Marc Z Simmons 1 collaboration

Parisa Momtaz 1 collaboration

Marina Shcherba 1 collaboration

Geoffrey Y Ku 1 collaboration

Alice Zervoudakis 1 collaboration

Elizabeth S Won 1 collaboration

David P Kelsen 1 collaboration

David H Ilson 1 collaboration

Rebecca J Nagy 1 collaboration

Richard B Lanman 1 collaboration

Mark T A Donoghue 1 collaboration

Marinela Capanu 1 collaboration

Barry S Taylor 1 collaboration

Nikolaus Schultz 1 collaboration

Jaclyn F Hechtman 1 collaboration

James P Solomon 1 collaboration

Soo-Ryum Yang 1 collaboration

Noura J Choudhury 1 collaboration

Nasrin Eslamdoost 1 collaboration

Christina J Falcon 1 collaboration

Axel Martin 1 collaboration

Andrew Plodkowski 1 collaboration

Clare Wilhelm 1 collaboration

Michael Berger 1 collaboration

Alexander Drilon 1 collaboration