Christopher J Thibodeaux

Affiliations

Department of Chemistry and Centre de Recherche en Biologie Structurale, McGill University, 801 Sherbrooke Street West, Montréal, Québec H3A 0B8, Canada.

ORCID: 0000-0002-4792-8362

Publications (16)

Exploring the Conformational Landscape of a Lanthipeptide Synthetase Using Native Mass Spectrometry.

Biochemistry

Avec: Nuwani W Weerasinghe , Yeganeh Habibi , Kevin A Uggowitzer ,

Partially Modified Peptide Intermediates in Lanthipeptide Biosynthesis Alter the Structure and Dynamics of a Lanthipeptide Synthetase.

Journal of the American Chemical Society

Avec: Yeganeh Habibi , Nuwani W Weerasinghe , Kevin A Uggowitzer ,

A naturally occurring G11S mutation in the 3C-like protease from the SARS-CoV-2 virus dramatically weakens the dimer interface.

Protein science : a publication of the Protein Society

Avec: Guanyu Wang , Felipe Venegas , Andres Rueda , Nuwani Weerasinghe , Kevin A Uggowitzer , Nicolas Moitessier , Anthony K Mittermaier

Defining the Functional Properties of Cyclopropane Fatty Acid Synthase from Pseudomonas aeruginosa PAO1.

The Journal of biological chemistry

Avec: Vivian Ezeduru , Annie R Q Shao , Felipe A Venegas , Geoffrey McKay , Jacquelyn Rich , Dao Nguyen ,

Mutations in Dynamic Structural Elements Alter the Kinetics and Fidelity of the Multifunctional Class II Lanthipeptide Synthetase, HalM2.

Biochemistry

Avec: Kevin A Uggowitzer , Yeganeh Habibi , Wanlei Wei , Nicolas Moitessier ,

Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reductase.

Biochemistry

Avec: Julie Ducharme , Irina F Sevrioukova , Karine Auclair

A conserved SH3-like fold in diverse putative proteins tetramerizes into an oxidoreductase providing an antimicrobial resistance phenotype.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Avec: Claudèle Lemay-St-Denis , Lorea Alejaldre , Zakaria Jemouai , Kiana Lafontaine , Maxime St-Aubin , Katia Hitache , Donya Valikhani , Nuwani W Weerasinghe , Myriam Létourneau , Nicolas Doucet , Christian Baron , Janine N Copp , Joelle N Pelletier

Insights into the Dynamic Structural Properties of a Lanthipeptide Synthetase using Hydrogen-Deuterium Exchange Mass Spectrometry.

Journal of the American Chemical Society

Avec: Yeganeh Habibi , Kevin A Uggowitzer , Hassan Issak ,

Unraveling flavoenzyme reaction mechanisms using flavin analogues and linear free energy relationships.

Methods in enzymology

Avec: Wei-Chen Chang , Hung-Wen Liu

Compartmentalized processing of catechols during mussel byssus fabrication determines the destiny of DOPA.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Tobias Priemel , Ranveer Palia , Margaryta Babych , Steve Bourgault , Matthew J Harrington

Evaluation of Quatsome Morphology, Composition, and Stability for

Langmuir : the ACS journal of surfaces and colloids

Avec: Changyue Du , Sascha Woolcott , Alexander Sean Wahba , Sally R Hamry , William L Odette , Patrick Marchand , Janine Mauzeroll

Purification, crystallization and crystallographic analysis of the PorX response regulator associated with the type IX secretion system.

Acta crystallographica. Section F, Structural biology communications

Avec: Anshu Saran , Nuwani Weerasinghe , Natalie Zeytuni

The conformationally dynamic structural biology of lanthipeptide biosynthesis.

Current opinion in structural biology

Avec:

Combining Small-Molecule Bioconjugation and Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) to Expose Allostery: the Case of Human Cytochrome P450 3A4.

ACS chemical biology

Avec: Julie Ducharme , Vanja Polic , Karine Auclair

A Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Platform for Investigating Peptide Biosynthetic Enzymes.

Journal of visualized experiments : JoVE

Avec: Yeganeh Habibi ,

Exploring the Heterogeneous Structural Dynamics of Class II Lanthipeptide Synthetases with Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS).

Biochemistry

Avec: Kevin A Uggowitzer , Annie R Q Shao , Yeganeh Habibi , Qianyi E Zhang ,

Réseau de co-auteurs

Yeganeh Habibi 6 collaborations

Kevin A Uggowitzer 6 collaborations

Nuwani W Weerasinghe 3 collaborations

Nuwani Weerasinghe 2 collaborations

Nicolas Moitessier 2 collaborations

Annie R Q Shao 2 collaborations

Julie Ducharme 2 collaborations

Karine Auclair 2 collaborations

Guanyu Wang 1 collaboration

Felipe Venegas 1 collaboration

Andres Rueda 1 collaboration

Anthony K Mittermaier 1 collaboration

Vivian Ezeduru 1 collaboration

Felipe A Venegas 1 collaboration

Geoffrey McKay 1 collaboration

Jacquelyn Rich 1 collaboration

Dao Nguyen 1 collaboration

Wanlei Wei 1 collaboration

Irina F Sevrioukova 1 collaboration

Claudèle Lemay-St-Denis 1 collaboration

Lorea Alejaldre 1 collaboration

Zakaria Jemouai 1 collaboration

Kiana Lafontaine 1 collaboration

Maxime St-Aubin 1 collaboration

Katia Hitache 1 collaboration

Donya Valikhani 1 collaboration

Myriam Létourneau 1 collaboration

Nicolas Doucet 1 collaboration

Christian Baron 1 collaboration

Janine N Copp 1 collaboration

Joelle N Pelletier 1 collaboration

Hassan Issak 1 collaboration

Wei-Chen Chang 1 collaboration

Hung-Wen Liu 1 collaboration

Tobias Priemel 1 collaboration

Ranveer Palia 1 collaboration

Margaryta Babych 1 collaboration

Steve Bourgault 1 collaboration

Matthew J Harrington 1 collaboration

Changyue Du 1 collaboration

Sascha Woolcott 1 collaboration

Alexander Sean Wahba 1 collaboration

Sally R Hamry 1 collaboration

William L Odette 1 collaboration

Patrick Marchand 1 collaboration

Janine Mauzeroll 1 collaboration

Anshu Saran 1 collaboration

Natalie Zeytuni 1 collaboration

Vanja Polic 1 collaboration

Qianyi E Zhang 1 collaboration