Bruno Hagenbuch

Affiliations

Department of Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center, Kansas City, KS 66160, USA.

ORCID: 0000-0002-2938-8630

Publications (21)

Free Cholesterol Affects the Function and Localization of Human Na

International journal of molecular sciences

Avec: Jessica Y Idowu ,

G45 and V386 in Transmembrane Domains 1 and 8 Are Critical for the Activation of OATP1B3-Mediated E17βG Uptake by Clotrimazole.

Molecular pharmaceutics

Avec: Wanjun Han , Zheyue Bo , Ting Liang , Han Liu , Lanjing Li , Zhening Guo , Ru Huan , Chunshan Gui

Perfluoroalkyl Carboxylic Acids Interact with the Human Bile Acid Transporter NTCP.

Livers

Avec: Melissa J Ruggiero , Haley Miller , Jessica Y Idowu , Jeremiah D Zitzow , Shu-Ching Chang ,

Drug metabolism and disposition: the biological fate of chemicals

Avec: Han Liu , Lanjing Li , Ting Liang , Ru Huan , Chunshan Gui

A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model.

The Journal of pharmacology and experimental therapeutics

Avec: Michelle L Montonye , Dan-Dan Tian , Tarana Arman , Katherine D Lynch , Mary F Paine , John D Clarke

The Importance of Val386 in Transmembrane Domain 8 for the Activation of OATP1B3 by Epigallocatechin Gallate.

Journal of agricultural and food chemistry

Avec: Zhongmin Wang , Ying Li , Cecilia E Villanueva , Taotao Peng , Wanjun Han , Zheyue Bo , Hongjian Zhang , Chunshan Gui

Investigating the interactions of flavonoids with human OATP2B1: inhibition assay, IC

RSC medicinal chemistry

Avec: Taotao Peng , Shuai Liu , Ying Li , Hongjian Zhang , Chunshan Gui

Molecular Mechanisms of Organic Anion Transporting Polypeptide-Mediated Organic Anion Clearance at the Blood-Cerebrospinal Fluid Barrier.

Molecular pharmacology

Avec: Austin Sun , Edward J Kelly , Joanne Wang

Rheostat positions: A new classification of protein positions relevant to pharmacogenomics.

Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents

Avec: Aron W Fenton , Braelyn M Page , Arianna Spellman-Kruse , Liskin Swint-Kruse

Gly45 and Phe555 in Transmembrane Domains 1 and 10 Are Critical for the Activation of Organic Anion Transporting Polypeptide 1B3 by Epigallocatechin Gallate.

Journal of agricultural and food chemistry

Avec: Mei Yue , Jingjie Yang , Meng Jin , Brianna Steiert , Yiqun Xiang , Hongjian Zhang , Chunshan Gui

Protein-protein interactions of drug uptake transporters that are important for liver and kidney.

Biochemical pharmacology

Avec: Yuchen Zhang ,

The Concise Guide to PHARMACOLOGY 2023/24: Transporters.

British journal of pharmacology

Avec: Stephen P H Alexander , Doriano Fabbro , Eamonn Kelly , Alistair A Mathie , John A Peters , Emma L Veale , Jane F Armstrong , Elena Faccenda , Simon D Harding , Jamie A Davies , Laura Amarosi , Catriona M H Anderson , Philip M Beart , Stefan Broer , Paul A Dawson , Gergely Gyimesi , James R Hammond , Jules C Hancox , Michal Hershfinkel , Ken-Ichi Inui , Yoshikatsu Kanai , Stephan Kemp , Edmund R S Kunji , Gavin Stewart , Sotiria Tavoulari , David T Thwaites , Tiziano Verri

Palmitoylation of solute carriers.

Biochemical pharmacology

Avec: Cecilia E Villanueva ,

Dynamic Contrast-Enhanced MRI of OATP Dysfunction in Diabetes.

Diabetes

Avec: Dorela D Shuboni-Mulligan , Maciej Parys , Barbara Blanco-Fernandez , Christiane L Mallett , Regina Schnegelberger , Marilia Takada , Shatadru Chakravarty , Erik M Shapiro

Functional Consequences of Pravastatin Isomerization on OATP1B1-Mediated Transport.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Jonathan B Wagner , Melissa Ruggiero , J Steven Leeder ,

OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Yuchen Zhang , Melissa Ruggiero ,

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters.

British journal of pharmacology

Avec: Stephen Ph Alexander , Eamonn Kelly , Alistair Mathie , John A Peters , Emma L Veale , Jane F Armstrong , Elena Faccenda , Simon D Harding , Adam J Pawson , Christopher Southan , Jamie A Davies , Laura Amarosi , Catriona M H Anderson , Philip Mark Beart , Stefan Broer , Paul A Dawson , James R Hammond , Ken-Ichi Inui , Yoshikatsu Kanai , Stephan Kemp , Gavin Stewart , David T Thwaites , Tiziano Verri

A clinically relevant polymorphism in the Na

The Journal of biological chemistry

Avec: Melissa J Ruggiero , Shipra Malhotra , Aron W Fenton , Liskin Swint-Kruse , John Karanicolas ,

Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms.

Toxicology

Avec: Melvin E Andersen , Udayan Apte , J Christopher Corton , Tony Fletcher , Christopher Lau , William L Roth , Bart Staels , Gloria L Vega , Harvey J Clewell , Matthew P Longnecker

Structural Plasticity Is a Feature of Rheostat Positions in the Human Na

International journal of molecular sciences

Avec: Melissa J Ruggiero , Shipra Malhotra , Aron W Fenton , Liskin Swint-Kruse , John Karanicolas ,

Using a competitive counterflow assay to identify novel cationic substrates of OATP1B1 and OATP1B3.

Frontiers in physiology

Avec: Regina D Schnegelberger , Brianna Steiert , Philip J Sandoval ,

Réseau de co-auteurs

Chunshan Gui 5 collaborations

Melissa J Ruggiero 3 collaborations

Hongjian Zhang 3 collaborations

Aron W Fenton 3 collaborations

Liskin Swint-Kruse 3 collaborations

Jessica Y Idowu 2 collaborations

Wanjun Han 2 collaborations

Zheyue Bo 2 collaborations

Ting Liang 2 collaborations

Han Liu 2 collaborations

Lanjing Li 2 collaborations

Ru Huan 2 collaborations

Ying Li 2 collaborations

Cecilia E Villanueva 2 collaborations

Taotao Peng 2 collaborations

Brianna Steiert 2 collaborations

Yuchen Zhang 2 collaborations

Eamonn Kelly 2 collaborations

John A Peters 2 collaborations

Emma L Veale 2 collaborations

Jane F Armstrong 2 collaborations

Elena Faccenda 2 collaborations

Simon D Harding 2 collaborations

Jamie A Davies 2 collaborations

Laura Amarosi 2 collaborations

Catriona M H Anderson 2 collaborations

Stefan Broer 2 collaborations

Paul A Dawson 2 collaborations

James R Hammond 2 collaborations

Ken-Ichi Inui 2 collaborations

Yoshikatsu Kanai 2 collaborations

Stephan Kemp 2 collaborations

Gavin Stewart 2 collaborations

David T Thwaites 2 collaborations

Tiziano Verri 2 collaborations

Melissa Ruggiero 2 collaborations

Shipra Malhotra 2 collaborations

John Karanicolas 2 collaborations

Zhening Guo 1 collaboration

Haley Miller 1 collaboration

Jeremiah D Zitzow 1 collaboration

Shu-Ching Chang 1 collaboration

Michelle L Montonye 1 collaboration

Dan-Dan Tian 1 collaboration

Tarana Arman 1 collaboration

Katherine D Lynch 1 collaboration

Mary F Paine 1 collaboration

John D Clarke 1 collaboration

Zhongmin Wang 1 collaboration

Shuai Liu 1 collaboration

Austin Sun 1 collaboration

Edward J Kelly 1 collaboration

Joanne Wang 1 collaboration

Braelyn M Page 1 collaboration

Arianna Spellman-Kruse 1 collaboration

Mei Yue 1 collaboration

Jingjie Yang 1 collaboration

Meng Jin 1 collaboration

Yiqun Xiang 1 collaboration

Stephen P H Alexander 1 collaboration

Doriano Fabbro 1 collaboration

Alistair A Mathie 1 collaboration

Philip M Beart 1 collaboration

Gergely Gyimesi 1 collaboration

Jules C Hancox 1 collaboration

Michal Hershfinkel 1 collaboration

Edmund R S Kunji 1 collaboration

Sotiria Tavoulari 1 collaboration

Dorela D Shuboni-Mulligan 1 collaboration

Maciej Parys 1 collaboration

Barbara Blanco-Fernandez 1 collaboration

Christiane L Mallett 1 collaboration

Regina Schnegelberger 1 collaboration

Marilia Takada 1 collaboration

Shatadru Chakravarty 1 collaboration

Erik M Shapiro 1 collaboration

Jonathan B Wagner 1 collaboration

J Steven Leeder 1 collaboration

Stephen Ph Alexander 1 collaboration

Alistair Mathie 1 collaboration

Adam J Pawson 1 collaboration

Christopher Southan 1 collaboration

Philip Mark Beart 1 collaboration

Melvin E Andersen 1 collaboration

Udayan Apte 1 collaboration

J Christopher Corton 1 collaboration

Tony Fletcher 1 collaboration

Christopher Lau 1 collaboration

William L Roth 1 collaboration

Bart Staels 1 collaboration

Gloria L Vega 1 collaboration

Harvey J Clewell 1 collaboration

Matthew P Longnecker 1 collaboration

Regina D Schnegelberger 1 collaboration

Philip J Sandoval 1 collaboration