Antonio DiGiandomenico

Affiliations

Discovery Microbiome, Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, USA.

Publications (24)

Using a community-based participatory research approach to meaningfully engage those with lived experience of diabetes and homelessness.

BMJ open diabetes research & care

Avec: David J T Campbell , Rachel B Campbell , Anna DiGiandomenico , Matthew Larsen , Marleane A Davidson , Kerry McBrien , Gillian L Booth , Stephen W Hwang

The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis.

NPJ biofilms and microbiomes

Avec: Amanda J Morris , Lindsay Jackson , Yvonne Cw Yau , Courtney Reichhardt , Trevor Beaudoin , Stephanie Uwumarenogie , Kevin M Guttman , P Lynne Howell , Matthew R Parsek , Lucas R Hoffman , Dao Nguyen , David S Guttman , Daniel J Wozniak , Valerie J Waters

Multicomponent Pseudomonas aeruginosa Vaccines Eliciting Th17 Cells and Functional Antibody Responses Confer Enhanced Protection against Experimental Acute Pneumonia in Mice.

Infection and immunity

Avec: Mohammad Omar Faruk Shaikh , Matthew M Schaefers , Christina Merakou , Marco DiBlasi , Sarah Bonney , Tiffany Liao , David Zurakowski , Margaret Kehl , David E Tabor , Gregory P Priebe

Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model.

Antimicrobial agents and chemotherapy

Avec: Fábio Aguiar-Alves , Hoan N Le , Vuvi G Tran , Emmanuelle Gras , Trang T T Vu , Oliver X Dong , Josiane Silva Quetz , Lily I Cheng , Li Yu , Bret R Sellman , Charles K Stover , Binh An Diep

Multifunctional Monoclonal Antibody Targeting

Vaccines

Avec: Wesley Hebert , Michael Zegans

Unmet needs in the management of exacerbations of chronic obstructive pulmonary disease.

Internal and emergency medicine

Avec: Kiki Waeijen-Smit , Sarah Houben-Wilke , Ulf Gehrmann , Frits M E Franssen

Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion.

Cell host & microbe

Avec: Ajitha Thanabalasuriar , Brittney Noelle Vivian Scott , Moritz Peiseler , Michelle Elizabeth Willson , Zhutian Zeng , Paul Warrener , Ashley Elaine Keller , Bas Gerardus Johannes Surewaard , Elizabeth Ashley Dozier , Juha Tapio Korhonen , Lily I-Ting Cheng , Mihaela Gadjeva , C Kendall Stover , Paul Kubes

Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.

Annals of the rheumatic diseases

Avec: Bo Chen , Katherine A Vousden , Brian Naiman , Sean Turman , Hong Sun , Shu Wang , Lisa M K Vinall , Benjamin P Kemp , Srinath Kasturiangan , D Gareth Rees , Ethan Grant , Mary Jane Hinrichs , Steven Eck , M Jack Borrok , Neang Ly , Ximing Xiong , Carlos Gonzalez , Christopher Morehouse , Yue Wang , Yebin Zhou , Jennifer Cann , Weiguang Zhao , Holly Koelkebeck , Koshu Okubo , Tanya N Mayadas , David Howe , Janet Griffiths , Roland Kolbeck , Ronald Herbst , Gary P Sims

In vivo expression of an mRNA encoded multi-mechanistic mAb combination against Staphylococcus aureus and protection in disease model.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Christine Tkaczyk , Michael Newton , Mun Mun Patnaik , George Thom , Martin Strain , Adam Gamson , Olalekan Daramola , Andal Murthy , Julie Douthwaite , Oleg Stepanov , Elin Boger , Haitao Yang , Mark T Esser , Ashley Lidwell , Luis Santos , Bret R Sellman

Pseudomonas aeruginosa aggregation and Psl expression in sputum is associated with antibiotic eradication failure in children with cystic fibrosis.

Scientific reports

Avec: Amanda J Morris , Yvonne C W Yau , Subin Park , Shafinaz Eisha , Nancy McDonald , Matthew R Parsek , P Lynne Howell , Lucas R Hoffman , Dao Nguyen , Ashley M Rooney , Bryan Coburn , Lucia Grana-Miraglia , Pauline Wang , David S Guttman , Daniel J Wozniak , Valerie J Waters

A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens.

Science translational medicine

Avec: Jun Yan , Travis B Nielsen , Peggy Lu , Yuli Talyansky , Matt Slarve , Hernan Reza , Boris Novakovic , Mihai G Netea , Ashley E Keller , Troy Warren , Bret R Sellman , Brian M Luna , Brad Spellberg

Differential

Frontiers in immunology

Avec: Barbara C Mindt , John Kim , Troy Warren , Yang Song ,

Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis.

Cell

Avec: Arpan Sharma Neupane , Michelle Willson , Andrew Krzysztof Chojnacki , Fernanda Vargas E Silva Castanheira , Christopher Morehouse , Agostina Carestia , Ashley Elaine Keller , Moritz Peiseler , Margaret Mary Kelly , Matthias Amrein , Craig Jenne , Ajitha Thanabalasuriar , Paul Kubes

A

Vaccines

Avec: Zennia Jean C Gonzaga , Christina Merakou , Gregory P Priebe , Bernd H A Rehm

Microbiome Modulation as a Novel Strategy to Treat and Prevent Respiratory Infections.

Antibiotics (Basel, Switzerland)

Avec: Barbara C Mindt ,

Early diagnostic BioMARKers in exacerbations of chronic obstructive pulmonary disease: protocol of the exploratory, prospective, longitudinal, single-centre, observational MARKED study.

BMJ open

Avec: Kiki Waeijen-Smit , Jessica Bonnell , Kristoffer Ostridge , Ulf Gehrmann , Bret R Sellman , Tara Kenny , Sander van Kuijk , Daphne Peerlings , Martijn A Spruit , Sami O Simons , Sarah Houben-Wilke , Frits M E Franssen

Efficacy of a

Infection and immunity

Avec: Dina A Moustafa , Vishnu Raghuram , Marc Schulman , Jennifer M Scarff , Michael R Davis , John J Varga , Charles R Dean , Joanna B Goldberg

A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of

American journal of respiratory and critical care medicine

Avec: Merete B Long , Amy Gilmour , Margaret Kehl , David Tabor , Ashley E Keller , Paul Warrener , Vancheswaran Gopalakrishnan , Sanna Rosengren , Megan L Crichton , Eve McIntosh , Yan Hui Giam , Holly R Keir , Wayne Brailsford , Rod Hughes , Maria G Belvisi , Bret R Sellman , James D Chalmers

Frontline Science: Employing enzymatic treatment options for management of ocular biofilm-based infections.

Journal of leukocyte biology

Avec: Abirami Kugadas , Jennifer Geddes-McAlister , Emilia Guy , David B Sykes , Michael K Mansour , Rossen Mirchev , Mihaela Gadjeva

Phase 1 study of MEDI3902, an investigational anti-Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Avec: S O Ali , X Q Yu , G J Robbie , Y Wu , K Shoemaker , L Yu , A DiGiandomenico , A E Keller , C Anude , M Hernandez-Illas , T Bellamy , J Falloon , F Dubovsky , H S Jafri

PD-L1

Science advances

Avec: Ajitha Thanabalasuriar , Abby J Chiang , Christopher Morehouse , Margarita Camara , Shonda Hawkins , Ashley E Keller , Adem C Koksal , Carolina S Caceres , Aaron A Berlin , Nicholas Holoweckyj , Virginia N Takahashi , Lily Cheng , Melissa de Los Reyes , Mark Pelletier , Andriani C Patera , Bret Sellman , Sonja Hess , Marcello Marelli , Chelsea C Boo , Taylor S Cohen ,

Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial.

Critical care (London, England)

Avec: Jean Chastre , Bruno François , Marc Bourgeois , Apostolos Komnos , Ricard Ferrer , Galia Rahav , Nicolas De Schryver , Alain Lepape , Iftihar Koksal , Charles-Edouard Luyt , Miguel Sánchez-García , Antoni Torres , Philippe Eggimann , Despoina Koulenti , Thomas L Holland , Omar Ali , Kathryn Shoemaker , Pin Ren , Julien Sauser , Alexey Ruzin , David E Tabor , Ahmad Akhgar , Yuling Wu , Yu Jiang , Susan Colbert , Drieke Vandamme , Frank Coenjaerts , Surbhi Malhotra-Kumar , Leen Timbermont , Antonio Oliver , Olivier Barraud , Terramika Bellamy , Marc Bonten , Herman Goossens , Colin Reisner , Mark T Esser , Hasan S Jafri , Auteur inconnu

Efficacy of a

bioRxiv : the preprint server for biology

Avec: Dina A Moustafa , Vishnu Raghuram , Marc Schulman , Jennifer M Scarff , Michael R Davis , John J Varga , Charles R Dean , Joanna B Goldberg

Development and validation of a rabbit model of

Frontiers in cellular and infection microbiology

Avec: Emmanuelle Gras , Trang T T Vu , Nhu T Q Nguyen , Vuvi G Tran , Yanjie Mao , Nguyen D Tran , Nam H Mai , Oliver X Dong , David H Jung , Natalia L P P Iorio , Helvecio C C Povoa , Marcos Gabriel Pinheiro , Fabio Aguiar-Alves , William J Weiss , Bo Zheng , Lily I Cheng , Charles K Stover , Bret R Sellman , Laure Gibault , Florent Valour , Binh An Diep

Réseau de co-auteurs

Bret R Sellman 6 collaborations

Ajitha Thanabalasuriar 3 collaborations

Christopher Morehouse 3 collaborations

Ashley E Keller 3 collaborations

Amanda J Morris 2 collaborations

P Lynne Howell 2 collaborations

Matthew R Parsek 2 collaborations

Lucas R Hoffman 2 collaborations

Dao Nguyen 2 collaborations

David S Guttman 2 collaborations

Daniel J Wozniak 2 collaborations

Valerie J Waters 2 collaborations

Christina Merakou 2 collaborations

Margaret Kehl 2 collaborations

David E Tabor 2 collaborations

Gregory P Priebe 2 collaborations

Vuvi G Tran 2 collaborations

Emmanuelle Gras 2 collaborations

Trang T T Vu 2 collaborations

Oliver X Dong 2 collaborations

Lily I Cheng 2 collaborations

Charles K Stover 2 collaborations

Binh An Diep 2 collaborations

Kiki Waeijen-Smit 2 collaborations

Sarah Houben-Wilke 2 collaborations

Ulf Gehrmann 2 collaborations

Frits M E Franssen 2 collaborations

Moritz Peiseler 2 collaborations

Paul Warrener 2 collaborations

Ashley Elaine Keller 2 collaborations

Mihaela Gadjeva 2 collaborations

Paul Kubes 2 collaborations

Mark T Esser 2 collaborations

Troy Warren 2 collaborations

Barbara C Mindt 2 collaborations

Dina A Moustafa 2 collaborations

Vishnu Raghuram 2 collaborations

Marc Schulman 2 collaborations

Jennifer M Scarff 2 collaborations

Michael R Davis 2 collaborations

John J Varga 2 collaborations

Charles R Dean 2 collaborations

Joanna B Goldberg 2 collaborations

David J T Campbell 1 collaboration

Rachel B Campbell 1 collaboration

Anna DiGiandomenico 1 collaboration

Matthew Larsen 1 collaboration

Marleane A Davidson 1 collaboration

Kerry McBrien 1 collaboration

Gillian L Booth 1 collaboration

Stephen W Hwang 1 collaboration

Lindsay Jackson 1 collaboration

Yvonne Cw Yau 1 collaboration

Courtney Reichhardt 1 collaboration

Trevor Beaudoin 1 collaboration

Stephanie Uwumarenogie 1 collaboration

Kevin M Guttman 1 collaboration

Mohammad Omar Faruk Shaikh 1 collaboration

Matthew M Schaefers 1 collaboration

Marco DiBlasi 1 collaboration

Sarah Bonney 1 collaboration

Tiffany Liao 1 collaboration

David Zurakowski 1 collaboration

Fábio Aguiar-Alves 1 collaboration

Hoan N Le 1 collaboration

Josiane Silva Quetz 1 collaboration

Li Yu 1 collaboration

Wesley Hebert 1 collaboration

Michael Zegans 1 collaboration

Brittney Noelle Vivian Scott 1 collaboration

Michelle Elizabeth Willson 1 collaboration

Zhutian Zeng 1 collaboration

Bas Gerardus Johannes Surewaard 1 collaboration

Elizabeth Ashley Dozier 1 collaboration

Juha Tapio Korhonen 1 collaboration

Lily I-Ting Cheng 1 collaboration

C Kendall Stover 1 collaboration

Bo Chen 1 collaboration

Katherine A Vousden 1 collaboration

Brian Naiman 1 collaboration

Sean Turman 1 collaboration

Hong Sun 1 collaboration

Shu Wang 1 collaboration

Lisa M K Vinall 1 collaboration

Benjamin P Kemp 1 collaboration

Srinath Kasturiangan 1 collaboration

D Gareth Rees 1 collaboration

Ethan Grant 1 collaboration

Mary Jane Hinrichs 1 collaboration

Steven Eck 1 collaboration

M Jack Borrok 1 collaboration

Neang Ly 1 collaboration

Ximing Xiong 1 collaboration

Carlos Gonzalez 1 collaboration

Yue Wang 1 collaboration

Yebin Zhou 1 collaboration

Jennifer Cann 1 collaboration

Weiguang Zhao 1 collaboration

Holly Koelkebeck 1 collaboration

Koshu Okubo 1 collaboration

Tanya N Mayadas 1 collaboration

David Howe 1 collaboration

Janet Griffiths 1 collaboration

Roland Kolbeck 1 collaboration

Ronald Herbst 1 collaboration

Gary P Sims 1 collaboration

Christine Tkaczyk 1 collaboration

Michael Newton 1 collaboration

Mun Mun Patnaik 1 collaboration

George Thom 1 collaboration

Martin Strain 1 collaboration

Adam Gamson 1 collaboration

Olalekan Daramola 1 collaboration

Andal Murthy 1 collaboration

Julie Douthwaite 1 collaboration

Oleg Stepanov 1 collaboration

Elin Boger 1 collaboration

Haitao Yang 1 collaboration

Ashley Lidwell 1 collaboration

Luis Santos 1 collaboration

Yvonne C W Yau 1 collaboration

Subin Park 1 collaboration

Shafinaz Eisha 1 collaboration

Nancy McDonald 1 collaboration

Ashley M Rooney 1 collaboration

Bryan Coburn 1 collaboration

Lucia Grana-Miraglia 1 collaboration

Pauline Wang 1 collaboration

Jun Yan 1 collaboration

Travis B Nielsen 1 collaboration

Peggy Lu 1 collaboration

Yuli Talyansky 1 collaboration

Matt Slarve 1 collaboration

Hernan Reza 1 collaboration

Boris Novakovic 1 collaboration

Mihai G Netea 1 collaboration

Brian M Luna 1 collaboration

Brad Spellberg 1 collaboration

John Kim 1 collaboration

Yang Song 1 collaboration

Arpan Sharma Neupane 1 collaboration

Michelle Willson 1 collaboration

Andrew Krzysztof Chojnacki 1 collaboration

Fernanda Vargas E Silva Castanheira 1 collaboration

Agostina Carestia 1 collaboration

Margaret Mary Kelly 1 collaboration

Matthias Amrein 1 collaboration

Craig Jenne 1 collaboration

Zennia Jean C Gonzaga 1 collaboration

Bernd H A Rehm 1 collaboration

Jessica Bonnell 1 collaboration

Kristoffer Ostridge 1 collaboration

Tara Kenny 1 collaboration

Sander van Kuijk 1 collaboration

Daphne Peerlings 1 collaboration

Martijn A Spruit 1 collaboration

Sami O Simons 1 collaboration

Merete B Long 1 collaboration

Amy Gilmour 1 collaboration

David Tabor 1 collaboration

Vancheswaran Gopalakrishnan 1 collaboration

Sanna Rosengren 1 collaboration

Megan L Crichton 1 collaboration

Eve McIntosh 1 collaboration

Yan Hui Giam 1 collaboration

Holly R Keir 1 collaboration

Wayne Brailsford 1 collaboration

Rod Hughes 1 collaboration

Maria G Belvisi 1 collaboration

James D Chalmers 1 collaboration

Abirami Kugadas 1 collaboration

Jennifer Geddes-McAlister 1 collaboration

Emilia Guy 1 collaboration

David B Sykes 1 collaboration

Michael K Mansour 1 collaboration

Rossen Mirchev 1 collaboration

S O Ali 1 collaboration

X Q Yu 1 collaboration

G J Robbie 1 collaboration

Y Wu 1 collaboration

K Shoemaker 1 collaboration

L Yu 1 collaboration

A DiGiandomenico 1 collaboration

A E Keller 1 collaboration

C Anude 1 collaboration

M Hernandez-Illas 1 collaboration

T Bellamy 1 collaboration

J Falloon 1 collaboration

F Dubovsky 1 collaboration

H S Jafri 1 collaboration

Abby J Chiang 1 collaboration

Margarita Camara 1 collaboration

Shonda Hawkins 1 collaboration

Adem C Koksal 1 collaboration

Carolina S Caceres 1 collaboration

Aaron A Berlin 1 collaboration

Nicholas Holoweckyj 1 collaboration

Virginia N Takahashi 1 collaboration

Lily Cheng 1 collaboration

Melissa de Los Reyes 1 collaboration

Mark Pelletier 1 collaboration

Andriani C Patera 1 collaboration

Bret Sellman 1 collaboration

Sonja Hess 1 collaboration

Marcello Marelli 1 collaboration

Chelsea C Boo 1 collaboration

Taylor S Cohen 1 collaboration

Jean Chastre 1 collaboration

Bruno François 1 collaboration

Marc Bourgeois 1 collaboration

Apostolos Komnos 1 collaboration

Ricard Ferrer 1 collaboration

Galia Rahav 1 collaboration

Nicolas De Schryver 1 collaboration

Alain Lepape 1 collaboration

Iftihar Koksal 1 collaboration

Charles-Edouard Luyt 1 collaboration

Miguel Sánchez-García 1 collaboration

Antoni Torres 1 collaboration

Philippe Eggimann 1 collaboration

Despoina Koulenti 1 collaboration

Thomas L Holland 1 collaboration

Omar Ali 1 collaboration

Kathryn Shoemaker 1 collaboration

Pin Ren 1 collaboration

Julien Sauser 1 collaboration

Alexey Ruzin 1 collaboration

Ahmad Akhgar 1 collaboration

Yuling Wu 1 collaboration

Yu Jiang 1 collaboration

Susan Colbert 1 collaboration

Drieke Vandamme 1 collaboration

Frank Coenjaerts 1 collaboration

Surbhi Malhotra-Kumar 1 collaboration

Leen Timbermont 1 collaboration

Antonio Oliver 1 collaboration

Olivier Barraud 1 collaboration

Terramika Bellamy 1 collaboration

Marc Bonten 1 collaboration

Herman Goossens 1 collaboration

Colin Reisner 1 collaboration

Hasan S Jafri 1 collaboration

None None 1 collaboration

Nhu T Q Nguyen 1 collaboration

Yanjie Mao 1 collaboration

Nguyen D Tran 1 collaboration

Nam H Mai 1 collaboration

David H Jung 1 collaboration

Natalia L P P Iorio 1 collaboration

Helvecio C C Povoa 1 collaboration

Marcos Gabriel Pinheiro 1 collaboration

Fabio Aguiar-Alves 1 collaboration

William J Weiss 1 collaboration

Bo Zheng 1 collaboration

Laure Gibault 1 collaboration

Florent Valour 1 collaboration