Anna Gazumyan

Affiliations

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Publications (54)

A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations.

Cell host & microbe

Avec: Qiao Wang , Eleftherios Michailidis , Yingpu Yu , Zijun Wang , Arlene M Hurley , Deena A Oren , Christian T Mayer , Zhenmi Liu , Yunjiao Zhou , Till Schoofs , Kai-Hui Yao , Jan P Nieke , Jianbo Wu , Qingling Jiang , Chenhui Zou , Mohanmmad Kabbani , Corrine Quirk , Thiago Oliveira , Kalsang Chhosphel , Qianqian Zhang , William M Schneider , Cyprien Jahan , Tianlei Ying , Jill Horowitz , Marina Caskey , Mila Jankovic , Davide F Robbiani , Yumei Wen , Ype P de Jong , Charles M Rice , Michel C Nussenzweig

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.

Nature

Avec: Amelia Escolano , Harry B Gristick , Morgan E Abernathy , Julia Merkenschlager , Rajeev Gautam , Thiago Y Oliveira , Joy Pai , Anthony P West , Christopher O Barnes , Alexander A Cohen , Haoqing Wang , Jovana Golijanin , Daniel Yost , Jennifer R Keeffe , Zijun Wang , Peng Zhao , Kai-Hui Yao , Jens Bauer , Lilian Nogueira , Han Gao , Alisa V Voll , David C Montefiori , Michael S Seaman , Murillo Silva , Andrew T McGuire , Leonidas Stamatatos , Darrell J Irvine , Lance Wells , Malcolm A Martin , Pamela J Bjorkman , Michel C Nussenzweig

HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells.

The Journal of experimental medicine

Avec: Harald Hartweger , Andrew T McGuire , Marcel Horning , Justin J Taylor , Pia Dosenovic , Daniel Yost , Michael S Seaman , Leonidas Stamatatos , Mila Jankovic , Michel C Nussenzweig

Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo.

The Journal of experimental medicine

Avec: Alexandra Schäfer , Frauke Muecksch , Julio C C Lorenzi , Sarah R Leist , Melissa Cipolla , Stylianos Bournazos , Fabian Schmidt , Rachel M Maison , David R Martinez , Ralph S Baric , Davide F Robbiani , Theodora Hatziioannou , Jeffrey V Ravetch , Paul D Bieniasz , Richard A Bowen , Michel C Nussenzweig , Timothy P Sheahan

Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.

The Journal of experimental medicine

Avec: Marianna Agudelo , Martin Palus , Jennifer R Keeffe , Filippo Bianchini , Pavel Svoboda , Jiří Salát , Avery Peace , Melissa Cipolla , Tania Kapoor , Francesca Guidetti , Kai-Hui Yao , Jana Elsterová , Dana Teislerová , Aleš Chrdle , Václav Hönig , Thiago Oliveira , Anthony P West , Yu E Lee , Charles M Rice , Margaret R MacDonald , Pamela J Bjorkman , Daniel Růžek , Davide F Robbiani , Michel C Nussenzweig

Evolution of antibody immunity to SARS-CoV-2.

Nature

Avec: Christian Gaebler , Zijun Wang , Julio C C Lorenzi , Frauke Muecksch , Shlomo Finkin , Minami Tokuyama , Alice Cho , Mila Jankovic , Dennis Schaefer-Babajew , Thiago Y Oliveira , Melissa Cipolla , Charlotte Viant , Christopher O Barnes , Yaron Bram , Gaëlle Breton , Thomas Hägglöf , Pilar Mendoza , Arlene Hurley , Martina Turroja , Kristie Gordon , Katrina G Millard , Victor Ramos , Fabian Schmidt , Yiska Weisblum , Divya Jha , Michael Tankelevich , Gustavo Martinez-Delgado , Jim Yee , Roshni Patel , Juan Dizon , Cecille Unson-O'Brien , Irina Shimeliovich , Davide F Robbiani , Zhen Zhao , Robert E Schwartz , Theodora Hatziioannou , Pamela J Bjorkman , Saurabh Mehandru , Paul D Bieniasz , Marina Caskey , Michel C Nussenzweig

Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination.

Nature

Avec: Dennis Schaefer-Babajew , Zijun Wang , Frauke Muecksch , Alice Cho , Maximilian Loewe , Melissa Cipolla , Raphael Raspe , Brianna Johnson , Marie Canis , Justin DaSilva , Victor Ramos , Martina Turroja , Katrina G Millard , Fabian Schmidt , Leander Witte , Juan Dizon , Irina Shimeliovich , Kai-Hui Yao , Thiago Y Oliveira , Christian Gaebler , Paul D Bieniasz , Theodora Hatziioannou , Marina Caskey , Michel C Nussenzweig

SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity.

bioRxiv : the preprint server for biology

Avec: Fengwen Zhang , Fabian Schmidt , Frauke Muecksch , Zijun Wang , Michel C Nussenzweig , Christian Gaebler , Marina Caskey , Theodora Hatziioannou , Paul D Bieniasz

Role of affinity in plasma cell development in the germinal center light zone.

The Journal of experimental medicine

Avec: Mohamed A ElTanbouly , Victor Ramos , Andrew J MacLean , Spencer T Chen , Maximilian Loewe , Sandra Steinbach , Tarek Ben Tanfous , Brianna Johnson , Melissa Cipolla , Thiago Y Oliveira , Michel C Nussenzweig

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.

eLife

Avec: Yiska Weisblum , Fabian Schmidt , Fengwen Zhang , Justin DaSilva , Daniel Poston , Julio Cc Lorenzi , Frauke Muecksch , Magdalena Rutkowska , Hans-Heinrich Hoffmann , Eleftherios Michailidis , Christian Gaebler , Marianna Agudelo , Alice Cho , Zijun Wang , Melissa Cipolla , Larry Luchsinger , Christopher D Hillyer , Marina Caskey , Davide F Robbiani , Charles M Rice , Michel C Nussenzweig , Theodora Hatziioannou , Paul D Bieniasz

Enhanced SARS-CoV-2 neutralization by dimeric IgA.

Science translational medicine

Avec: Zijun Wang , Julio C C Lorenzi , Frauke Muecksch , Shlomo Finkin , Charlotte Viant , Christian Gaebler , Melissa Cipolla , Hans-Heinrich Hoffmann , Thiago Y Oliveira , Deena A Oren , Victor Ramos , Lilian Nogueira , Eleftherios Michailidis , Davide F Robbiani , Charles M Rice , Theodora Hatziioannou , Paul D Bieniasz , Marina Caskey , Michel C Nussenzweig

A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Koen K A Van Rompay , Lark L Coffey , Tania Kapoor , Rebekah I Keesler , Andrea Jurado , Avery Peace , Marianna Agudelo , Jennifer Watanabe , Jodie Usachenko , Anil Singapuri , Ramya Immareddy , Amir Ardeshir , Jackson B Stuart , Stylianos Bournazos , Jeffrey V Ravetch , Paul J Balderes , Ivo C Lorenz , Shannon R Esswein , Jennifer R Keeffe , Pamela J Bjorkman , Qiao Wang , Charles M Rice , Margaret R MacDonald , Michel C Nussenzweig , Davide F Robbiani

Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies.

Nature communications

Avec: David A Garber , Debra R Adams , Patricia Guenthner , James Mitchell , Kristen Kelley , Till Schoofs , Martha Nason , Michael S Seaman , Janet McNicholl , Michel C Nussenzweig , Walid Heneine

Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals.

bioRxiv : the preprint server for biology

Avec: Davide F Robbiani , Christian Gaebler , Frauke Muecksch , Julio C C Lorenzi , Zijun Wang , Alice Cho , Marianna Agudelo , Christopher O Barnes , Shlomo Finkin , Thomas Hagglof , Thiago Y Oliveira , Charlotte Viant , Arlene Hurley , Hans-Heinrich Hoffmann , Katrina G Millard , Rhonda G Kost , Melissa Cipolla , Kristie Gordon , Filippo Bianchini , Spencer T Chen , Victor Ramos , Roshni Patel , Juan Dizon , Irina Shimeliovich , Pilar Mendoza , Harald Hartweger , Lilian Nogueira , Maggi Pack , Jill Horowitz , Fabian Schmidt , Yiska Weisblum , Eleftherios Michailidis , Alison W Ashbrook , Eric Waltari , John E Pak , Kathryn E Huey-Tubman , Nicholas Koranda , Pauline R Hoffman , Anthony P West , Charles M Rice , Theodora Hatziioannou , Pamela J Bjorkman , Paul D Bieniasz , Marina Caskey , Michel C Nussenzweig

Plasma and memory antibody responses to Gamma SARS-CoV-2 provide limited cross-protection to other variants.

The Journal of experimental medicine

Avec: Marianna Agudelo , Frauke Muecksch , Dennis Schaefer-Babajew , Alice Cho , Justin DaSilva , Eva Bednarski , Victor Ramos , Thiago Y Oliveira , Melissa Cipolla , Shuai Zong , Danielle A S Rodrigues , Guilherme S Lira , Luciana Conde , Renato Santana Aguiar , Orlando C Ferreira , Amilcar Tanuri , Katia C Affonso , Rafael M Galliez , Terezinha Marta Pereira Pinto Castineiras , Juliana Echevarria-Lima , Marcelo Torres Bozza , Andre M Vale , Paul D Bieniasz , Theodora Hatziioannou , Michel C Nussenzweig

Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses.

Cell reports

Avec: Tomás Cervantes Rincón , Tania Kapoor , Jennifer R Keeffe , Luca Simonelli , Hans-Heinrich Hoffmann , Marianna Agudelo , Andrea Jurado , Avery Peace , Yu E Lee , Francesca Guidetti , Jasmine Cantergiani , Benedetta Cena , Filippo Bianchini , Elia Tamagnini , Simone G Moro , Pavel Svoboda , Federico Costa , Mitermayer G Reis , Albert I Ko , Brian A Fallon , Santiago Avila-Rios , Gustavo Reyes-Téran , Charles M Rice , Michel C Nussenzweig , Pamela J Bjorkman , Daniel Ruzek , Luca Varani , Margaret R MacDonald , Davide F Robbiani

Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens.

The Journal of experimental medicine

Avec: Zijun Wang , Frauke Muecksch , Friederike Muenn , Alice Cho , Shuai Zong , Raphael Raspe , Victor Ramos , Brianna Johnson , Tarek Ben Tanfous , Justin DaSilva , Eva Bednarski , Camila Guzman-Cardozo , Martina Turroja , Katrina G Millard , Pinkus Tober-Lau , David Hillus , Kai-Hui Yao , Irina Shimeliovich , Juan Dizon , Anna Kaczynska , Mila Jankovic , Thiago Y Oliveira , Marina Caskey , Paul D Bieniasz , Theodora Hatziioannou , Florian Kurth , Leif Erik Sander , Michel C Nussenzweig , Christian Gaebler

SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity.

mBio

Avec: Fengwen Zhang , Fabian Schmidt , Frauke Muecksch , Zijun Wang , Michel C Nussenzweig , Christian Gaebler , Marina Caskey , Theodora Hatziioannou , Paul D Bieniasz

Broadly neutralizing antibody-mediated protection of macaques against repeated intravenous exposures to simian-human immunodeficiency virus.

AIDS (London, England)

Avec: David A Garber , Patricia Guenthner , James Mitchell , Shanon Ellis , Martha Nason , Michael S Seaman , Janet M McNicholl , Michel C Nussenzweig , Walid Heneine

Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env.

Science translational medicine

Avec: Amelia Escolano , Harry B Gristick , Rajeev Gautam , Andrew T DeLaitsch , Morgan E Abernathy , Zhi Yang , Haoqing Wang , Magnus A G Hoffmann , Yoshiaki Nishimura , Zijun Wang , Nicholas Koranda , Leesa M Kakutani , Han Gao , Priyanthi N P Gnanapragasam , Henna Raina , Ana Gazumyan , Melissa Cipolla , Thiago Y Oliveira , Victor Ramos , Darrell J Irvine , Murillo Silva , Anthony P West , Jennifer R Keeffe , Christopher O Barnes , Michael S Seaman , Michel C Nussenzweig , Malcolm A Martin , Pamela J Bjorkman

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants.

Nature

Avec: Zijun Wang , Fabian Schmidt , Yiska Weisblum , Frauke Muecksch , Christopher O Barnes , Shlomo Finkin , Dennis Schaefer-Babajew , Melissa Cipolla , Christian Gaebler , Jenna A Lieberman , Thiago Y Oliveira , Zhi Yang , Morgan E Abernathy , Kathryn E Huey-Tubman , Arlene Hurley , Martina Turroja , Kamille A West , Kristie Gordon , Katrina G Millard , Victor Ramos , Justin Da Silva , Jianliang Xu , Robert A Colbert , Roshni Patel , Juan Dizon , Cecille Unson-O'Brien , Irina Shimeliovich , Marina Caskey , Pamela J Bjorkman , Rafael Casellas , Theodora Hatziioannou , Paul D Bieniasz , Michel C Nussenzweig

Dynamic regulation of T

Nature

Avec: Julia Merkenschlager , Shlomo Finkin , Victor Ramos , Julian Kraft , Melissa Cipolla , Carla R Nowosad , Harald Hartweger , Wenzhu Zhang , Paul Dominic B Olinares , Thiago Y Oliveira , Brian T Chait , Michel C Nussenzweig

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants.

bioRxiv : the preprint server for biology

Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins.

bioRxiv : the preprint server for biology

Avec: Zijun Wang , Frauke Muecksch , Alice Cho , Christian Gaebler , Hans-Heinrich Hoffmann , Victor Ramos , Shuai Zong , Melissa Cipolla , Briana Johnson , Fabian Schmidt , Justin DaSilva , Eva Bednarski , Tarek Ben Tanfous , Raphael Raspe , Kaihui Yao , Yu E Lee , Teresia Chen , Martina Turroja , Katrina G Milard , Juan Dizon , Anna Kaczynska , Thiago Y Oliveira , Charles M Rice , Marina Caskey , Paul D Bieniasz , Theodora Hatziioannou , Christopher O Barnes , Michel C Nussenzweig

Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine in humans.

The Journal of experimental medicine

Avec: Alice Cho , Frauke Muecksch , Zijun Wang , Tarek Ben Tanfous , Justin DaSilva , Raphael Raspe , Brianna Johnson , Eva Bednarski , Victor Ramos , Dennis Schaefer-Babajew , Irina Shimeliovich , Juan P Dizon , Kai-Hui Yao , Fabian Schmidt , Katrina G Millard , Martina Turroja , Mila Jankovic , Thiago Y Oliveira , Christian Gaebler , Marina Caskey , Theodora Hatziioannou , Paul D Bieniasz , Michel C Nussenzweig

Memory B cell development elicited by mRNA booster vaccinations in the elderly.

The Journal of experimental medicine

Avec: Zijun Wang , Frauke Muecksch , Raphael Raspe , Frederik Johannsen , Martina Turroja , Marie Canis , Mohamed A ElTanbouly , Gabriela S Silva Santos , Brianna Johnson , Viren A Baharani , Rachel Patejak , Kai-Hui Yao , Bennett J Chirco , Katrina G Millard , Irina Shimeliovich , Thiago Y Oliveira , Paul D Bieniasz , Theodora Hatziioannou , Marina Caskey , Michel C Nussenzweig

Broadly neutralizing antibody-mediated protection against simian-HIV infection among macaques with vaginal sexually transmitted infections.

AIDS (London, England)

Avec: David A Garber , Patricia Guenthner , Chunxia Zhao , James Mitchell , Shanon Ellis , Hongwei Jia , Marcos Manganare , Michael S Seaman , Sundaram Ajay Vishwanathan , Walid Heneine , Janet M McNicholl

Convergent antibody responses to SARS-CoV-2 in convalescent individuals.

Nature

Avec: Davide F Robbiani , Christian Gaebler , Frauke Muecksch , Julio C C Lorenzi , Zijun Wang , Alice Cho , Marianna Agudelo , Christopher O Barnes , Shlomo Finkin , Thomas Hägglöf , Thiago Y Oliveira , Charlotte Viant , Arlene Hurley , Hans-Heinrich Hoffmann , Katrina G Millard , Rhonda G Kost , Melissa Cipolla , Kristie Gordon , Filippo Bianchini , Spencer T Chen , Victor Ramos , Roshni Patel , Juan Dizon , Irina Shimeliovich , Pilar Mendoza , Harald Hartweger , Lilian Nogueira , Maggi Pack , Jill Horowitz , Fabian Schmidt , Yiska Weisblum , Eleftherios Michailidis , Alison W Ashbrook , Eric Waltari , John E Pak , Kathryn E Huey-Tubman , Nicholas Koranda , Pauline R Hoffman , Anthony P West , Charles M Rice , Theodora Hatziioannou , Pamela J Bjorkman , Paul D Bieniasz , Marina Caskey , Michel C Nussenzweig

Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Alice Cho , Christian Gaebler , Thiago Olveira , Victor Ramos , Marwa Saad , Julio C C Lorenzi , Susan Moir , Marina Caskey , Tae-Wook Chun , Michel C Nussenzweig

Evolution of Antibody Immunity to SARS-CoV-2.

bioRxiv : the preprint server for biology

Avec: Christian Gaebler , Zijun Wang , Julio C C Lorenzi , Frauke Muecksch , Shlomo Finkin , Minami Tokuyama , Alice Cho , Mila Jankovic , Dennis Schaefer-Babajew , Thiago Y Oliveira , Melissa Cipolla , Charlotte Viant , Christopher O Barnes , Arlene Hurley , Martina Turroja , Kristie Gordon , Katrina G Millard , Victor Ramos , Fabian Schmidt , Yiska Weisblum , Divya Jha , Michael Tankelevich , Jim Yee , Irina Shimeliovich , Davide F Robbiani , Zhen Zhao , Theodora Hatziioannou , Pamela J Bjorkman , Saurabh Mehandru , Paul D Bieniasz , Marina Caskey , Michel C Nussenzweig , Thomas Hagglof , Robert E Schwartz , Yaron Bram , Gustavo Martinez-Delgado , Pilar Mendoza , Gaelle Breton , Juan Dizon , Cecille Unson-O'Brien , Roshni Patel

Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro.

bioRxiv : the preprint server for biology

Avec: Zijun Wang , Julio C C Lorenzi , Frauke Muecksch , Shlomo Finkin , Charlotte Viant , Christian Gaebler , Melissa Cipolla , Hans-Heinrich Hoffman , Thiago Y Oliveira , Deena A Oren , Victor Ramos , Lilian Nogueira , Eleftherios Michailidis , Davide F Robbiani , Charles M Rice , Theodora Hatziioannou , Paul D Bieniasz , Marina Caskey , Michel C Nussenzweig

Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose.

bioRxiv : the preprint server for biology

Avec: Frauke Muecksch , Zijun Wang , Alice Cho , Christian Gaebler , Tarek Ben Tanfous , Justin DaSilva , Eva Bednarski , Victor Ramos , Shuai Zong , Brianna Johnson , Raphael Raspe , Dennis Schaefer-Babajew , Irina Shimeliovich , Mridushi Daga , Kai-Hui Yao , Fabian Schmidt , Katrina G Millard , Martina Turroja , Mila Jankovic , Thiago Y Oliveria , Marina Caskey , Theodora Hatziioannou , Paul D Bieniasz , Michel C Nussenzweig

Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost.

Nature

Avec: Frauke Muecksch , Zijun Wang , Alice Cho , Christian Gaebler , Tarek Ben Tanfous , Justin DaSilva , Eva Bednarski , Victor Ramos , Shuai Zong , Brianna Johnson , Raphael Raspe , Dennis Schaefer-Babajew , Irina Shimeliovich , Mridushi Daga , Kai-Hui Yao , Fabian Schmidt , Katrina G Millard , Martina Turroja , Mila Jankovic , Thiago Y Oliveira , Marina Caskey , Theodora Hatziioannou , Paul D Bieniasz , Michel C Nussenzweig

Antibody feedback regulation of memory B cell development in SARS-CoV-2 mRNA vaccination.

medRxiv : the preprint server for health sciences

Avec: Dennis Schaefer-Babajew , Zijun Wang , Frauke Muecksch , Alice Cho , Raphael Raspe , Brianna Johnson , Marie Canis , Justin DaSilva , Victor Ramos , Martina Turroja , Katrina G Millard , Fabian Schmidt , Juan Dizon , Irina Shimelovich , Kai-Hui Yao , Thiago Y Oliveira , Christian Gaebler , Paul D Bieniasz , Theodora Hatziioannou , Marina Caskey , Michel C Nussenzweig

Continuous germinal center invasion contributes to the diversity of the immune response.

Cell

Avec: Thomas Hägglöf , Melissa Cipolla , Maximilian Loewe , Spencer T Chen , Luka Mesin , Harald Hartweger , Mohamed A ElTanbouly , Alice Cho , Victor Ramos , Leonidas Stamatatos , Thiago Y Oliveira , Michel C Nussenzweig , Charlotte Viant

B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection.

Immunity

Avec: Spencer T Chen , Thiago Y Oliveira , Melissa Cipolla , Michel C Nussenzweig

Risk of Zika microcephaly correlates with features of maternal antibodies.

The Journal of experimental medicine

Avec: Davide F Robbiani , Priscilla C Olsen , Federico Costa , Qiao Wang , Thiago Y Oliveira , Nivison Nery , Adeolu Aromolaran , Mateus S do Rosário , Gielson A Sacramento , Jaqueline S Cruz , Ricardo Khouri , Elsio A Wunder , Adriana Mattos , Bruno de Paula Freitas , Manoel Sarno , Gracinda Archanjo , Dina Daltro , Gustavo B S Carvalho , Kleber Pimentel , Isadora C de Siqueira , João R M de Almeida , Daniele F Henriques , Juliana A Lima , Pedro F C Vasconcelos , Dennis Schaefer-Babajew , Stephanie A Azzopardi , Leonia Bozzacco , Rubens Belfort , Ana P Alcântara , Gustavo Carvalho , Licia Moreira , Katiaci Araujo , Mitermayer G Reis , Rebekah I Keesler , Lark L Coffey , Jennifer Tisoncik-Go , Michael Gale , Lakshmi Rajagopal , Kristina M Adams Waldorf , Dawn M Dudley , Heather A Simmons , Andres Mejia , David H O'Connor , Rosemary J Steinbach , Nicole Haese , Jessica Smith , Anne Lewis , Lois Colgin , Victoria Roberts , Antonio Frias , Meredith Kelleher , Alec Hirsch , Daniel N Streblow , Charles M Rice , Margaret R MacDonald , Antonio R P de Almeida , Koen K A Van Rompay , Albert I Ko , Michel C Nussenzweig

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.

bioRxiv : the preprint server for biology

Avec: Yiska Weisblum , Fabian Schmidt , Fengwen Zhang , Justin DaSilva , Daniel Poston , Julio C C Lorenzi , Frauke Muecksch , Magdalena Rutkowska , Hans-Heinrich Hoffmann , Eleftherios Michailidis , Christian Gaebler , Marianna Agudelo , Alice Cho , Zijun Wang , Melissa Cipolla , Larry Luchsinger , Christopher D Hillyer , Marina Caskey , Davide F Robbiani , Charles M Rice , Michel C Nussenzweig , Theodora Hatziioannou , Paul D Bieniasz

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.

The Journal of experimental medicine

Avec: Fabian Schmidt , Yiska Weisblum , Frauke Muecksch , Hans-Heinrich Hoffmann , Eleftherios Michailidis , Julio C C Lorenzi , Pilar Mendoza , Magdalena Rutkowska , Eva Bednarski , Christian Gaebler , Marianna Agudelo , Alice Cho , Zijun Wang , Melissa Cipolla , Marina Caskey , Davide F Robbiani , Michel C Nussenzweig , Charles M Rice , Theodora Hatziioannou , Paul D Bieniasz

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.

bioRxiv : the preprint server for biology

Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination.

Nature

Avec: Alice Cho , Frauke Muecksch , Dennis Schaefer-Babajew , Zijun Wang , Shlomo Finkin , Christian Gaebler , Victor Ramos , Melissa Cipolla , Pilar Mendoza , Marianna Agudelo , Eva Bednarski , Justin DaSilva , Irina Shimeliovich , Juan Dizon , Mridushi Daga , Katrina G Millard , Martina Turroja , Fabian Schmidt , Fengwen Zhang , Tarek Ben Tanfous , Mila Jankovic , Thiago Y Oliveria , Marina Caskey , Paul D Bieniasz , Theodora Hatziioannou , Michel C Nussenzweig

Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies.

bioRxiv : the preprint server for biology

Avec: Frauke Muecksch , Yiska Weisblum , Christopher O Barnes , Fabian Schmidt , Dennis Schaefer-Babajew , Julio C C Lorenzi , Andrew I Flyak , Andrew T DeLaitsch , Kathryn E Huey-Tubman , Shurong Hou , Celia A Schiffer , Christian Gaebler , Zijun Wang , Justin Da Silva , Daniel Poston , Shlomo Finkin , Alice Cho , Melissa Cipolla , Thiago Y Oliveira , Katrina G Millard , Victor Ramos , Magdalena Rutkowska , Marina Caskey , Michel C Nussenzweig , Pamela J Bjorkman , Theodora Hatziioannou , Paul D Bieniasz

A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.

eLife

Avec: Zijun Wang , Christopher O Barnes , Rajeev Gautam , Julio C Cetrulo Lorenzi , Christian T Mayer , Thiago Y Oliveira , Victor Ramos , Melissa Cipolla , Kristie M Gordon , Harry B Gristick , Anthony P West , Yoshiaki Nishimura , Henna Raina , Michael S Seaman , Malcolm Martin , Pamela J Bjorkman , Michel C Nussenzweig , Amelia Escolano

Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates.

Cell

Avec: Charlotte Viant , Georg H J Weymar , Amelia Escolano , Spencer Chen , Harald Hartweger , Melissa Cipolla , Michel C Nussenzweig

Naturally enhanced neutralizing breadth to SARS-CoV-2 after one year.

bioRxiv : the preprint server for biology

Avec: Zijun Wang , Frauke Muecksch , Dennis Schaefer-Babajew , Shlomo Finkin , Charlotte Viant , Christian Gaebler , Hans-Heinrich Hoffmann , Christopher O Barnes , Melissa Cipolla , Victor Ramos , Thiago Y Oliveira , Alice Cho , Fabian Schmidt , Justin da Silva , Eva Bednarski , Lauren Aguado , Jim Yee , Mridushi Daga , Martina Turroja , Katrina G Millard , Mila Jankovic , Zhen Zhao , Charles M Rice , Paul D Bieniasz , Marina Caskey , Theodora Hatziioannou , Michel C Nussenzweig

An apoptosis-dependent checkpoint for autoimmunity in memory B and plasma cells.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Christian T Mayer , Jan P Nieke , Melissa Cipolla , Qiao Wang , Thiago Y Oliveira , Victor Ramos , Sébastien Monette , Quan-Zhen Li , M Eric Gershwin , Hamid Kashkar , Michel C Nussenzweig

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection

bioRxiv : the preprint server for biology

Avec: Alexandra Schäfer , Frauke Muecksch , Julio C C Lorenzi , Sarah R Leist , Melissa Cipolla , Stylianos Bournazos , Fabian Schmidt , Ralph S Baric , Davide F Robbiani , Theodora Hatziioannou , Jeffrey V Ravetch , Paul D Bieniasz , Michel C Nussenzweig , Timothy P Sheahan

Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection.

Nature

Avec: Zijun Wang , Frauke Muecksch , Dennis Schaefer-Babajew , Shlomo Finkin , Charlotte Viant , Christian Gaebler , Hans- Heinrich Hoffmann , Christopher O Barnes , Melissa Cipolla , Victor Ramos , Thiago Y Oliveira , Alice Cho , Fabian Schmidt , Justin Da Silva , Eva Bednarski , Lauren Aguado , Jim Yee , Mridushi Daga , Martina Turroja , Katrina G Millard , Mila Jankovic , Zhen Zhao , Charles M Rice , Paul D Bieniasz , Marina Caskey , Theodora Hatziioannou , Michel C Nussenzweig

Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.

Immunity

Avec: Frauke Muecksch , Yiska Weisblum , Christopher O Barnes , Fabian Schmidt , Dennis Schaefer-Babajew , Zijun Wang , Julio C C Lorenzi , Andrew I Flyak , Andrew T DeLaitsch , Kathryn E Huey-Tubman , Shurong Hou , Celia A Schiffer , Christian Gaebler , Justin Da Silva , Daniel Poston , Shlomo Finkin , Alice Cho , Melissa Cipolla , Thiago Y Oliveira , Katrina G Millard , Victor Ramos , Magdalena Rutkowska , Marina Caskey , Michel C Nussenzweig , Pamela J Bjorkman , Theodora Hatziioannou , Paul D Bieniasz

Prolonged viral suppression with anti-HIV-1 antibody therapy.

Nature

Avec: Christian Gaebler , Lilian Nogueira , Elina Stoffel , Thiago Y Oliveira , Gaëlle Breton , Katrina G Millard , Martina Turroja , Allison Butler , Victor Ramos , Michael S Seaman , Jacqueline D Reeves , Christos J Petroupoulos , Irina Shimeliovich , Caroline S Jiang , Nikolaus Jilg , Johannes F Scheid , Rajesh Gandhi , Bruce D Walker , Michael C Sneller , Anthony Fauci , Tae-Wook Chun , Marina Caskey , Michel C Nussenzweig

Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.

Immunity

Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Trinity Zang , Edmund Osei Kuffour , Viren A Baharani , Marie Canis , Fabian Schmidt , Justin Da Silva , Alexander Lercher , Pooja Chaudhary , Hans-Heinrich Hoffmann , Ileana C Miranda , Margaret R MacDonald , Charles M Rice , Michel C Nussenzweig , Theodora Hatziioannou , Paul D Bieniasz

Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans.

The Journal of experimental medicine

Avec: Zijun Wang , Pengcheng Zhou , Frauke Muecksch , Alice Cho , Tarek Ben Tanfous , Marie Canis , Leander Witte , Brianna Johnson , Raphael Raspe , Fabian Schmidt , Eva Bednarski , Justin Da Silva , Victor Ramos , Shuai Zong , Martina Turroja , Katrina G Millard , Kai-Hui Yao , Irina Shimeliovich , Juan Dizon , Anna Kaczynska , Mila Jankovic , Thiago Y Oliveira , Marina Caskey , Christian Gaebler , Paul D Bieniasz , Theodora Hatziioannou , Michel C Nussenzweig

CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.

Science immunology

Avec: Harry B Gristick , Harald Hartweger , Maximilian Loewe , Jelle van Schooten , Victor Ramos , Thiago Y Oliveira , Yoshiaki Nishimura , Nicholas S Koranda , Abigail Wall , Kai-Hui Yao , Daniel Poston , Marie Wiatr , Marcel Horning , Jennifer R Keeffe , Magnus A G Hoffmann , Zhi Yang , Morgan E Abernathy , Kim-Marie A Dam , Han Gao , Priyanthi N P Gnanapragasam , Leesa M Kakutani , Ana Jimena Pavlovitch-Bedzyk , Michael S Seaman , Mark Howarth , Andrew T McGuire , Leonidas Stamatatos , Malcolm A Martin , Anthony P West , Michel C Nussenzweig , Pamela J Bjorkman

Réseau de co-auteurs

Michel C Nussenzweig 53 collaborations

Zijun Wang 33 collaborations

Thiago Y Oliveira 33 collaborations

Theodora Hatziioannou 33 collaborations

Paul D Bieniasz 33 collaborations

Marina Caskey 32 collaborations

Frauke Muecksch 32 collaborations

Melissa Cipolla 32 collaborations

Victor Ramos 32 collaborations

Christian Gaebler 30 collaborations

Fabian Schmidt 28 collaborations

Alice Cho 25 collaborations

Katrina G Millard 20 collaborations

Charles M Rice 18 collaborations

Martina Turroja 18 collaborations

Davide F Robbiani 17 collaborations

Dennis Schaefer-Babajew 16 collaborations

Christopher O Barnes 15 collaborations

Pamela J Bjorkman 15 collaborations

Irina Shimeliovich 15 collaborations

Julio C C Lorenzi 14 collaborations

Shlomo Finkin 14 collaborations

Juan Dizon 13 collaborations

Eva Bednarski 13 collaborations

Kai-Hui Yao 12 collaborations

Mila Jankovic 12 collaborations

Yiska Weisblum 12 collaborations

Justin DaSilva 12 collaborations

Hans-Heinrich Hoffmann 12 collaborations

Marianna Agudelo 11 collaborations

Charlotte Viant 10 collaborations

Raphael Raspe 10 collaborations

Eleftherios Michailidis 9 collaborations

Michael S Seaman 9 collaborations

Brianna Johnson 9 collaborations

Tarek Ben Tanfous 9 collaborations

Anthony P West 7 collaborations

Harald Hartweger 7 collaborations

Pilar Mendoza 7 collaborations

Shuai Zong 7 collaborations

Justin Da Silva 7 collaborations

Jennifer R Keeffe 6 collaborations

Lilian Nogueira 6 collaborations

Arlene Hurley 6 collaborations

Kristie Gordon 6 collaborations

Roshni Patel 6 collaborations

Magdalena Rutkowska 6 collaborations

Kathryn E Huey-Tubman 6 collaborations

Morgan E Abernathy 5 collaborations

Margaret R MacDonald 5 collaborations

Marie Canis 5 collaborations

Fengwen Zhang 5 collaborations

Spencer T Chen 5 collaborations

Daniel Poston 5 collaborations

Mridushi Daga 5 collaborations

Qiao Wang 4 collaborations

Amelia Escolano 4 collaborations

Harry B Gristick 4 collaborations

Leonidas Stamatatos 4 collaborations

Filippo Bianchini 4 collaborations

Yu E Lee 4 collaborations

Jim Yee 4 collaborations

Cecille Unson-O'Brien 4 collaborations

Zhen Zhao 4 collaborations

Maximilian Loewe 4 collaborations

Anna Kaczynska 4 collaborations

Zhi Yang 4 collaborations

Deena A Oren 3 collaborations

Christian T Mayer 3 collaborations

Jill Horowitz 3 collaborations

Rajeev Gautam 3 collaborations

Han Gao 3 collaborations

Andrew T McGuire 3 collaborations

Malcolm A Martin 3 collaborations

Stylianos Bournazos 3 collaborations

Jeffrey V Ravetch 3 collaborations

Avery Peace 3 collaborations

Tania Kapoor 3 collaborations

Thomas Hägglöf 3 collaborations

Mohamed A ElTanbouly 3 collaborations

David A Garber 3 collaborations

Patricia Guenthner 3 collaborations

James Mitchell 3 collaborations

Walid Heneine 3 collaborations

Nicholas Koranda 3 collaborations

Andrew T DeLaitsch 3 collaborations

Yoshiaki Nishimura 3 collaborations

Till Schoofs 2 collaborations

Jan P Nieke 2 collaborations

Thiago Oliveira 2 collaborations

Julia Merkenschlager 2 collaborations

Haoqing Wang 2 collaborations

Daniel Yost 2 collaborations

Murillo Silva 2 collaborations

Darrell J Irvine 2 collaborations

Marcel Horning 2 collaborations

Alexandra Schäfer 2 collaborations

Sarah R Leist 2 collaborations

Ralph S Baric 2 collaborations

Timothy P Sheahan 2 collaborations

Pavel Svoboda 2 collaborations

Francesca Guidetti 2 collaborations

Minami Tokuyama 2 collaborations

Yaron Bram 2 collaborations

Gaëlle Breton 2 collaborations

Divya Jha 2 collaborations

Michael Tankelevich 2 collaborations

Gustavo Martinez-Delgado 2 collaborations

Robert E Schwartz 2 collaborations

Saurabh Mehandru 2 collaborations

Leander Witte 2 collaborations

Larry Luchsinger 2 collaborations

Christopher D Hillyer 2 collaborations

Koen K A Van Rompay 2 collaborations

Lark L Coffey 2 collaborations

Rebekah I Keesler 2 collaborations

Andrea Jurado 2 collaborations

Martha Nason 2 collaborations

Thomas Hagglof 2 collaborations

Rhonda G Kost 2 collaborations

Maggi Pack 2 collaborations

Alison W Ashbrook 2 collaborations

Eric Waltari 2 collaborations

John E Pak 2 collaborations

Pauline R Hoffman 2 collaborations

Federico Costa 2 collaborations

Mitermayer G Reis 2 collaborations

Albert I Ko 2 collaborations

Shanon Ellis 2 collaborations

Janet M McNicholl 2 collaborations

Magnus A G Hoffmann 2 collaborations

Leesa M Kakutani 2 collaborations

Priyanthi N P Gnanapragasam 2 collaborations

Henna Raina 2 collaborations

Jenna A Lieberman 2 collaborations

Kamille A West 2 collaborations

Jianliang Xu 2 collaborations

Robert A Colbert 2 collaborations

Rafael Casellas 2 collaborations

Briana Johnson 2 collaborations

Kaihui Yao 2 collaborations

Teresia Chen 2 collaborations

Katrina G Milard 2 collaborations

Viren A Baharani 2 collaborations

Tae-Wook Chun 2 collaborations

Thiago Y Oliveria 2 collaborations

Andrew I Flyak 2 collaborations

Shurong Hou 2 collaborations

Celia A Schiffer 2 collaborations

Lauren Aguado 2 collaborations

Yingpu Yu 1 collaboration

Arlene M Hurley 1 collaboration

Zhenmi Liu 1 collaboration

Yunjiao Zhou 1 collaboration

Jianbo Wu 1 collaboration

Qingling Jiang 1 collaboration

Chenhui Zou 1 collaboration

Mohanmmad Kabbani 1 collaboration

Corrine Quirk 1 collaboration

Kalsang Chhosphel 1 collaboration

Qianqian Zhang 1 collaboration

William M Schneider 1 collaboration

Cyprien Jahan 1 collaboration

Tianlei Ying 1 collaboration

Yumei Wen 1 collaboration

Ype P de Jong 1 collaboration

Joy Pai 1 collaboration

Alexander A Cohen 1 collaboration

Jovana Golijanin 1 collaboration

Peng Zhao 1 collaboration

Jens Bauer 1 collaboration

Alisa V Voll 1 collaboration

David C Montefiori 1 collaboration

Lance Wells 1 collaboration

Justin J Taylor 1 collaboration

Pia Dosenovic 1 collaboration

Rachel M Maison 1 collaboration

David R Martinez 1 collaboration

Richard A Bowen 1 collaboration

Martin Palus 1 collaboration

Jiří Salát 1 collaboration

Jana Elsterová 1 collaboration

Dana Teislerová 1 collaboration

Aleš Chrdle 1 collaboration

Václav Hönig 1 collaboration

Daniel Růžek 1 collaboration

Andrew J MacLean 1 collaboration

Sandra Steinbach 1 collaboration

Julio Cc Lorenzi 1 collaboration

Jennifer Watanabe 1 collaboration

Jodie Usachenko 1 collaboration

Anil Singapuri 1 collaboration

Ramya Immareddy 1 collaboration

Amir Ardeshir 1 collaboration

Jackson B Stuart 1 collaboration

Paul J Balderes 1 collaboration

Ivo C Lorenz 1 collaboration

Shannon R Esswein 1 collaboration

Debra R Adams 1 collaboration

Kristen Kelley 1 collaboration

Janet McNicholl 1 collaboration

Danielle A S Rodrigues 1 collaboration

Guilherme S Lira 1 collaboration

Luciana Conde 1 collaboration

Renato Santana Aguiar 1 collaboration

Orlando C Ferreira 1 collaboration

Amilcar Tanuri 1 collaboration

Katia C Affonso 1 collaboration

Rafael M Galliez 1 collaboration

Terezinha Marta Pereira Pinto Castineiras 1 collaboration

Juliana Echevarria-Lima 1 collaboration

Marcelo Torres Bozza 1 collaboration

Andre M Vale 1 collaboration

Tomás Cervantes Rincón 1 collaboration

Luca Simonelli 1 collaboration

Jasmine Cantergiani 1 collaboration

Benedetta Cena 1 collaboration

Elia Tamagnini 1 collaboration

Simone G Moro 1 collaboration

Brian A Fallon 1 collaboration

Santiago Avila-Rios 1 collaboration

Gustavo Reyes-Téran 1 collaboration

Daniel Ruzek 1 collaboration

Luca Varani 1 collaboration

Friederike Muenn 1 collaboration

Camila Guzman-Cardozo 1 collaboration

Pinkus Tober-Lau 1 collaboration

David Hillus 1 collaboration

Florian Kurth 1 collaboration

Leif Erik Sander 1 collaboration

Ana Gazumyan 1 collaboration

Julian Kraft 1 collaboration

Carla R Nowosad 1 collaboration

Wenzhu Zhang 1 collaboration

Paul Dominic B Olinares 1 collaboration

Brian T Chait 1 collaboration

Juan P Dizon 1 collaboration

Frederik Johannsen 1 collaboration

Gabriela S Silva Santos 1 collaboration

Rachel Patejak 1 collaboration

Bennett J Chirco 1 collaboration

Chunxia Zhao 1 collaboration

Hongwei Jia 1 collaboration

Marcos Manganare 1 collaboration

Sundaram Ajay Vishwanathan 1 collaboration

Thiago Olveira 1 collaboration

Marwa Saad 1 collaboration

Susan Moir 1 collaboration

Gaelle Breton 1 collaboration

Hans-Heinrich Hoffman 1 collaboration

Irina Shimelovich 1 collaboration

Luka Mesin 1 collaboration

Priscilla C Olsen 1 collaboration

Nivison Nery 1 collaboration

Adeolu Aromolaran 1 collaboration

Mateus S do Rosário 1 collaboration

Gielson A Sacramento 1 collaboration

Jaqueline S Cruz 1 collaboration

Ricardo Khouri 1 collaboration

Elsio A Wunder 1 collaboration

Adriana Mattos 1 collaboration

Bruno de Paula Freitas 1 collaboration

Manoel Sarno 1 collaboration

Gracinda Archanjo 1 collaboration

Dina Daltro 1 collaboration

Gustavo B S Carvalho 1 collaboration

Kleber Pimentel 1 collaboration

Isadora C de Siqueira 1 collaboration

João R M de Almeida 1 collaboration

Daniele F Henriques 1 collaboration

Juliana A Lima 1 collaboration

Pedro F C Vasconcelos 1 collaboration

Stephanie A Azzopardi 1 collaboration

Leonia Bozzacco 1 collaboration

Rubens Belfort 1 collaboration

Ana P Alcântara 1 collaboration

Gustavo Carvalho 1 collaboration

Licia Moreira 1 collaboration

Katiaci Araujo 1 collaboration

Jennifer Tisoncik-Go 1 collaboration

Michael Gale 1 collaboration

Lakshmi Rajagopal 1 collaboration

Kristina M Adams Waldorf 1 collaboration

Dawn M Dudley 1 collaboration

Heather A Simmons 1 collaboration

Andres Mejia 1 collaboration

David H O'Connor 1 collaboration

Rosemary J Steinbach 1 collaboration

Nicole Haese 1 collaboration

Jessica Smith 1 collaboration

Anne Lewis 1 collaboration

Lois Colgin 1 collaboration

Victoria Roberts 1 collaboration

Antonio Frias 1 collaboration

Meredith Kelleher 1 collaboration

Alec Hirsch 1 collaboration

Daniel N Streblow 1 collaboration

Antonio R P de Almeida 1 collaboration

Julio C Cetrulo Lorenzi 1 collaboration

Kristie M Gordon 1 collaboration

Malcolm Martin 1 collaboration

Georg H J Weymar 1 collaboration

Spencer Chen 1 collaboration

Justin da Silva 1 collaboration

Sébastien Monette 1 collaboration

Quan-Zhen Li 1 collaboration

M Eric Gershwin 1 collaboration

Hamid Kashkar 1 collaboration

Hans- Heinrich Hoffmann 1 collaboration

Elina Stoffel 1 collaboration

Allison Butler 1 collaboration

Jacqueline D Reeves 1 collaboration

Christos J Petroupoulos 1 collaboration

Caroline S Jiang 1 collaboration

Nikolaus Jilg 1 collaboration

Johannes F Scheid 1 collaboration

Rajesh Gandhi 1 collaboration

Bruce D Walker 1 collaboration

Michael C Sneller 1 collaboration

Anthony Fauci 1 collaboration

Trinity Zang 1 collaboration

Edmund Osei Kuffour 1 collaboration

Alexander Lercher 1 collaboration

Pooja Chaudhary 1 collaboration

Ileana C Miranda 1 collaboration

Pengcheng Zhou 1 collaboration

Jelle van Schooten 1 collaboration

Nicholas S Koranda 1 collaboration

Abigail Wall 1 collaboration

Marie Wiatr 1 collaboration

Kim-Marie A Dam 1 collaboration

Ana Jimena Pavlovitch-Bedzyk 1 collaboration

Mark Howarth 1 collaboration