Alex Tonevitsky

Affiliations

Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russian Federation.
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russian Federation.

Publications (43)

Low expression of CD24 is associated with poor survival in colorectal cancer.

Biochimie

Avec: Stepan Nersisyan , Ann-Kristin Ahlers , Tobias Lange , Daniel Wicklein , Alexei Galatenko , Hanibal Bohnenberger , Omar Elakad , Lena-Christin Conradi , Sandra Genduso , Hanna Maar , Alina Schiecke , Diana Maltseva , Maria Raygorodskaya , Julia Makarova , Udo Schumacher , Alexander Tonevitsky

Extracellular miRNAs and Cell-Cell Communication: Problems and Prospects.

Trends in biochemical sciences

Avec: J Makarova , A Turchinovich , M Shkurnikov , A Tonevitsky

Differences in Medium-Induced Conformational Plasticity Presumably Underlie Different Cytotoxic Activity of Ricin and Viscumin.

Biomolecules

Avec: Pavel Volynsky , Diana Maltseva , Valentin Tabakmakher , Eduard V Bocharov , Maria Raygorodskaya , Galina Zakharova , Elena Britikova , Alexander Tonevitsky , Roman Efremov

Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules.

PeerJ

Avec: Stepan Nersisyan , Anton Zhiyanov , Maria Zakharova , Irina Ishina , Inna Kurbatskaia , Azad Mamedov , Alexei Galatenko , Maxim Shkurnikov , Alexander Gabibov , Alexander Tonevitsky

RNA-binding proteins regulating the CD44 alternative splicing.

Frontiers in molecular biosciences

Avec: Diana Maltseva , Alexander Tonevitsky

A novel approach for a joint analysis of isomiR and mRNA expression data reveals features of isomiR targeting in breast cancer.

Frontiers in genetics

Avec: Stepan Nersisyan , Anton Zhiyanov , Narek Engibaryan , Diana Maltseva , Alexander Tonevitsky

Incautious design of shRNAs for stable overexpression of miRNAs could result in generation of undesired isomiRs.

Biochimica et biophysica acta. Gene regulatory mechanisms

Avec: Diana Maltseva , Ivan Kirillov , Anton Zhiyanov , Daria Averinskaya , Roman Suvorov , Daria Gubani , Anna Kudriaeva , Alexey Belogurov , Alexander Tonevitsky

Impedance Spectroscopy as a Tool for Monitoring Performance in 3D Models of Epithelial Tissues.

Frontiers in bioengineering and biotechnology

Avec: Tatiana Gerasimenko , Sergey Nikulin , Galina Zakharova , Andrey Poloznikov , Vladimir Petrov , Ancha Baranova , Alexander Tonevitsky

Transcriptome of Extracellular Vesicles: State-of-the-Art.

Frontiers in immunology

Avec: Andrey Turchinovich , Oxana Drapkina , Alexander Tonevitsky

Hairpin sequence and structure is associated with features of isomiR biogenesis.

RNA biology

Avec: Anton Zhiyanov , Stepan Nersisyan , Alexander Tonevitsky

ExhauFS: exhaustive search-based feature selection for classification and survival regression.

PeerJ

Avec: Stepan Nersisyan , Victor Novosad , Alexei Galatenko , Andrey Sokolov , Grigoriy Bokov , Alexander Konovalov , Dmitry Alekseev , Alexander Tonevitsky

Specificity of viscumin revised. As probed with a printed glycan array.

Biochimie

Avec: Nadezhda Shilova , Nicolai Bovin , Diana Maltseva , Svetlana Polyakova , Marina Sablina , Hideaki Niwa , Galina Zakharova , Maria Raygorodskaya , Lyuba Bufeeva , Yury Belyi , Dmitry Hushpulian , Alexander Tonevitsky

isomiRTar: a comprehensive portal of pan-cancer 5'-isomiR targeting.

PeerJ

Avec: Stepan Nersisyan , Aleksandra Gorbonos , Alexey Makhonin , Anton Zhiyanov , Maxim Shkurnikov , Alexander Tonevitsky

Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria-related pathways in colorectal cancer.

Molecular oncology

Avec: Arun Everest-Dass , Stepan Nersisyan , Hanna Maar , Victor Novosad , Jennifer Schröder-Schwarz , Vera Freytag , Johanna L Stuke , Mia C Beine , Alina Schiecke , Marie-Therese Haider , Malte Kriegs , Omar Elakad , Hanibal Bohnenberger , Lena-Christin Conradi , Maria Raygorodskaya , Linda Krause , Mark von Itzstein , Alexander Tonevitsky , Udo Schumacher , Diana Maltseva , Daniel Wicklein , Tobias Lange

Differential co-expression network analysis with DCoNA reveals isomiR targeting aberrations in prostate cancer.

Bioinformatics (Oxford, England)

Avec: Anton Zhiyanov , Narek Engibaryan , Stepan Nersisyan , Maxim Shkurnikov , Alexander Tonevitsky

Mathematical model explains differences in Omicron and Delta SARS-CoV-2 dynamics in Caco-2 and Calu-3 cells.

PeerJ

Avec: Vladimir Staroverov , Alexei Galatenko , Evgeny Knyazev , Alexander Tonevitsky

Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

ALTEX

Avec: Uwe Marx , Takafumi Akabane , Tommy B Andersson , Elizabeth Baker , Mario Beilmann , Sonja Beken , Susanne Brendler-Schwaab , Murat Cirit , Rhiannon David , Eva-Maria Dehne , Isabell Durieux , Lorna Ewart , Suzanne C Fitzpatrick , Olivier Frey , Florian Fuchs , Linda G Griffith , Geraldine A Hamilton , Thomas Hartung , Julia Hoeng , Helena Hogberg , David J Hughes , Donald E Ingber , Anita Iskandar , Toshiyuki Kanamori , Hajime Kojima , Jochen Kuehnl , Marcel Leist , Bo Li , Peter Loskill , Donna L Mendrick , Thomas Neumann , Giorgia Pallocca , Ivan Rusyn , Lena Smirnova , Thomas Steger-Hartmann , Danilo A Tagle , Alexander Tonevitsky , Sergej Tsyb , Martin Trapecar , Bob Van de Water , Janny Van den Eijnden-van Raaij , Paul Vulto , Kengo Watanabe , Armin Wolf , Xiaobing Zhou , Adrian Roth

Association of HLA Class I Genotypes With Severity of Coronavirus Disease-19.

Frontiers in immunology

Avec: Maxim Shkurnikov , Stepan Nersisyan , Tatjana Jankevic , Alexei Galatenko , Ivan Gordeev , Valery Vechorko , Alexander Tonevitsky

miRGTF-net: Integrative miRNA-gene-TF network analysis reveals key drivers of breast cancer recurrence.

PloS one

Avec: Stepan Nersisyan , Alexei Galatenko , Vladimir Galatenko , Maxim Shkurnikov , Alexander Tonevitsky

Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury.

eLife

Avec: Nikolay Lukoyanov , Hiroyuki Watanabe , Liliana S Carvalho , Olga Kononenko , Daniil Sarkisyan , Mengliang Zhang , Marlene Storm Andersen , Elena A Lukoyanova , Vladimir Galatenko , Igor Bazov , Tatiana Iakovleva , Jens Schouenborg , Georgy Bakalkin

Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression.

Journal of experimental & clinical cancer research : CR

Avec: Marius Kemper , Alina Schiecke , Hanna Maar , Sergey Nikulin , Andrey Poloznikov , Vladimir Galatenko , Michael Tachezy , Florian Gebauer , Tobias Lange , Kristoffer Riecken , Alexander Tonevitsky , Achim Aigner , Jakob Izbicki , Udo Schumacher , Daniel Wicklein

Immunogenic epitope panel for accurate detection of non-cross-reactive T cell response to SARS-CoV-2.

JCI insight

Avec: Aleksei Titov , Regina Shaykhutdinova , Olga V Shcherbakova , Yana V Serdyuk , Savely A Sheetikov , Ksenia V Zornikova , Alexandra V Maleeva , Alexandra Khmelevskaya , Dmitry V Dianov , Naina T Shakirova , Dmitry B Malko , Maxim Shkurnikov , Stepan Nersisyan , Alexander Tonevitsky , Ekaterina Khamaganova , Anton V Ershov , Elena Y Osipova , Ruslan V Nikolaev , Dmitry E Pershin , Viktoria A Vedmedskia , Michael Maschan , Victoria R Ginanova , Grigory A Efimov

PeerJ

Avec: Maxim Shkurnikov , Stepan Nersisyan , Darya Averinskaya , Milena Chekova , Fedor Polyakov , Aleksei Titov , Dmitriy Doroshenko , Valery Vechorko , Alexander Tonevitsky

Viral and host small RNA transcriptome analysis of SARS-CoV-1 and SARS-CoV-2-infected human cells reveals novel viral short RNAs.

Heliyon

Avec: Tom A P Driedonks , Lyle H Nyberg , Abigail Conte , Zexu Ma , Andrew Pekosz , Eduard Duban , Alexander Tonevitsky , Holger Sültmann , Andrey Turchinovich , Kenneth W Witwer

Frontiers in molecular biosciences

Avec: Maxim Shkurnikov , Sergey Nikulin , Stepan Nersisyan , Andrey Poloznikov , Shan Zaidi , Ancha Baranova , Udo Schumacher , Daniel Wicklein , Alexander Tonevitsky

Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2.

PloS one

Avec: Stepan Nersisyan , Maxim Shkurnikov , Andrey Turchinovich , Evgeny Knyazev , Alexander Tonevitsky

Knockdown of the α5 laminin chain affects differentiation of colorectal cancer cells and their sensitivity to chemotherapy.

Biochimie

Avec: Diana Maltseva , Maria Raygorodskaya , Evgeny Knyazev , Victor Zgoda , Olga Tikhonova , Shan Zaidi , Sergey Nikulin , Ancha Baranova , Andrey Turchinovich , Sergey Rodin , Alexander Tonevitsky

A Post-Processing Algorithm for miRNA Microarray Data.

International journal of molecular sciences

Avec: Stepan Nersisyan , Maxim Shkurnikov , Andrey Poloznikov , Andrey Turchinovich , Barbara Burwinkel , Nikita Anisimov , Alexander Tonevitsky

Hypoxia-Induced miR-148a Downregulation Contributes to Poor Survival in Colorectal Cancer.

Frontiers in genetics

Avec: Stepan Nersisyan , Alexei Galatenko , Milena Chekova , Alexander Tonevitsky

Effect of the Expression of

Frontiers in genetics

Avec: Sergey Nikulin , Galina Zakharova , Andrey Poloznikov , Maria Raigorodskaya , Daniel Wicklein , Udo Schumacher , Stepan Nersisyan , Jonas Bergquist , Georgy Bakalkin , Lidiia Astakhova , Alexander Tonevitsky

Endocytosis and Transcytosis of SARS-CoV-2 Across the Intestinal Epithelium and Other Tissue Barriers.

Frontiers in immunology

Avec: Evgeny Knyazev , Stepan Nersisyan , Alexander Tonevitsky

9-ING-41, a Small Molecule Inhibitor of GSK-3β, Potentiates the Effects of Chemotherapy on Colorectal Cancer Cells.

Frontiers in pharmacology

Avec: Andrey Poloznikov , Sergey Nikulin , Larisa Bolotina , Andrei Kachmazov , Maria Raigorodskaya , Anna Kudryavtseva , Ildar Bakhtogarimov , Sergey Rodin , Irina Gaisina , Maxim Topchiy , Andrey Asachenko , Victor Novosad , Alexander Tonevitsky , Boris Alekseev

ECM-Receptor Regulatory Network and Its Prognostic Role in Colorectal Cancer.

Frontiers in genetics

Avec: Stepan Nersisyan , Victor Novosad , Narek Engibaryan , Yuri Ushkaryov , Sergey Nikulin , Alexander Tonevitsky

IGFBP6 regulates extracellular vesicles formation via cholesterol abundance in MDA-MB-231 cells.

Biochimie

Avec: Maxim Shkurnikov , Darya Averinskaya , Elena Stekolshchikova , Anna Serkina , Alexandra Razumovskaya , Maria Silkina , Ivan Antipenko , Julia Makarova , Ekaterina Evtushenko , Sergey Nikulin , Alexander Tonevitsky

On the peptide binding affinity changes in population-specific HLA repertoires to the SARS-CoV-2 variants Delta and Omicron.

Journal of autoimmunity

Avec: Lu-Chun Chen , Stepan Nersisyan , Chang-Jiun Wu , Che-Mai Chang , Alexander Tonevitsky , Chin-Lin Guo , Wei-Chiao Chang

Challenges in characterization of transcriptomes of extracellular vesicles and non-vesicular extracellular RNA carriers.

Frontiers in molecular biosciences

Avec: Julia Makarova , Diana Maltseva , Alexander Tonevitsky

Towards embedding Caco-2 model of gut interface in a microfluidic device to enable multi-organ models for systems biology.

BMC systems biology

Avec: Dmitry Sakharov , Diana Maltseva , Evgeny Knyazev , Sergey Nikulin , Andrey Poloznikov , Sergey Shilin , Ancha Baranova , Irina Tsypina , Alexander Tonevitsky

Adipose may actively delay progression of NAFLD by releasing tumor-suppressing, anti-fibrotic miR-122 into circulation.

Obesity reviews : an official journal of the International Association for the Study of Obesity

Avec: A Baranova , D Maltseva , A Tonevitsky

Potential role of cellular miRNAs in coronavirus-host interplay.

PeerJ

Avec: Stepan Nersisyan , Narek Engibaryan , Aleksandra Gorbonos , Ksenia Kirdey , Alexey Makhonin , Alexander Tonevitsky

T-CoV: a comprehensive portal of HLA-peptide interactions affected by SARS-CoV-2 mutations.

Nucleic acids research

Avec: Stepan Nersisyan , Anton Zhiyanov , Maxim Shkurnikov , Alexander Tonevitsky

Development of a novel mathematical model that explains SARS-CoV-2 infection dynamics in Caco-2 cells.

PeerJ

Avec: Vladimir Staroverov , Stepan Nersisyan , Alexei Galatenko , Dmitriy Alekseev , Sofya Lukashevich , Fedor Polyakov , Nikita Anisimov , Alexander Tonevitsky

The signature of SARS-CoV-2 evolution reflects selective pressures within human guts.

Journal of medical virology

Avec: Anton Zhiyanov , Maxim Shkurnikov , Ashot Nersisyan , Cai Hui , Ancha Baranova , Alexander Tonevitsky

Metabolic effects of vasopressin in pathophysiology of diabetic kidney disease.

Frontiers in endocrinology

Avec: Svetlana Lebedeva , Arus Margaryan , Elena Smolyarchuk , Andrey Nedorubov , Maria Materenchuk , Alexander Tonevitsky , Kerim Mutig

Réseau de co-auteurs

Alexander Tonevitsky 40 collaborations

Stepan Nersisyan 23 collaborations

Maxim Shkurnikov 13 collaborations

Diana Maltseva 10 collaborations

Sergey Nikulin 9 collaborations

Alexei Galatenko 8 collaborations

Anton Zhiyanov 8 collaborations

Andrey Poloznikov 7 collaborations

Daniel Wicklein 5 collaborations

Maria Raygorodskaya 5 collaborations

Udo Schumacher 5 collaborations

Ancha Baranova 5 collaborations

Andrey Turchinovich 5 collaborations

Evgeny Knyazev 5 collaborations

Galina Zakharova 4 collaborations

Narek Engibaryan 4 collaborations

Victor Novosad 4 collaborations

Tobias Lange 3 collaborations

Hanna Maar 3 collaborations

Alina Schiecke 3 collaborations

Julia Makarova 3 collaborations

Vladimir Galatenko 3 collaborations

Hanibal Bohnenberger 2 collaborations

Omar Elakad 2 collaborations

Lena-Christin Conradi 2 collaborations

A Tonevitsky 2 collaborations

Aleksandra Gorbonos 2 collaborations

Alexey Makhonin 2 collaborations

Vladimir Staroverov 2 collaborations

Valery Vechorko 2 collaborations

Georgy Bakalkin 2 collaborations

Aleksei Titov 2 collaborations

Darya Averinskaya 2 collaborations

Milena Chekova 2 collaborations

Fedor Polyakov 2 collaborations

Shan Zaidi 2 collaborations

Sergey Rodin 2 collaborations

Nikita Anisimov 2 collaborations

Maria Raigorodskaya 2 collaborations

Ann-Kristin Ahlers 1 collaboration

Sandra Genduso 1 collaboration

J Makarova 1 collaboration

A Turchinovich 1 collaboration

M Shkurnikov 1 collaboration

Pavel Volynsky 1 collaboration

Valentin Tabakmakher 1 collaboration

Eduard V Bocharov 1 collaboration

Elena Britikova 1 collaboration

Roman Efremov 1 collaboration

Maria Zakharova 1 collaboration

Irina Ishina 1 collaboration

Inna Kurbatskaia 1 collaboration

Azad Mamedov 1 collaboration

Alexander Gabibov 1 collaboration

Ivan Kirillov 1 collaboration

Daria Averinskaya 1 collaboration

Roman Suvorov 1 collaboration

Daria Gubani 1 collaboration

Anna Kudriaeva 1 collaboration

Alexey Belogurov 1 collaboration

Tatiana Gerasimenko 1 collaboration

Vladimir Petrov 1 collaboration

Oxana Drapkina 1 collaboration

Andrey Sokolov 1 collaboration

Grigoriy Bokov 1 collaboration

Alexander Konovalov 1 collaboration

Dmitry Alekseev 1 collaboration

Nadezhda Shilova 1 collaboration

Nicolai Bovin 1 collaboration

Svetlana Polyakova 1 collaboration

Marina Sablina 1 collaboration

Hideaki Niwa 1 collaboration

Lyuba Bufeeva 1 collaboration

Yury Belyi 1 collaboration

Dmitry Hushpulian 1 collaboration

Arun Everest-Dass 1 collaboration

Jennifer Schröder-Schwarz 1 collaboration

Vera Freytag 1 collaboration

Johanna L Stuke 1 collaboration

Mia C Beine 1 collaboration

Marie-Therese Haider 1 collaboration

Malte Kriegs 1 collaboration

Linda Krause 1 collaboration

Mark von Itzstein 1 collaboration

Uwe Marx 1 collaboration

Takafumi Akabane 1 collaboration

Tommy B Andersson 1 collaboration

Elizabeth Baker 1 collaboration

Mario Beilmann 1 collaboration

Sonja Beken 1 collaboration

Susanne Brendler-Schwaab 1 collaboration

Murat Cirit 1 collaboration

Rhiannon David 1 collaboration

Eva-Maria Dehne 1 collaboration

Isabell Durieux 1 collaboration

Lorna Ewart 1 collaboration

Suzanne C Fitzpatrick 1 collaboration

Olivier Frey 1 collaboration

Florian Fuchs 1 collaboration

Linda G Griffith 1 collaboration

Geraldine A Hamilton 1 collaboration

Thomas Hartung 1 collaboration

Julia Hoeng 1 collaboration

Helena Hogberg 1 collaboration

David J Hughes 1 collaboration

Donald E Ingber 1 collaboration

Anita Iskandar 1 collaboration

Toshiyuki Kanamori 1 collaboration

Hajime Kojima 1 collaboration

Jochen Kuehnl 1 collaboration

Marcel Leist 1 collaboration

Bo Li 1 collaboration

Peter Loskill 1 collaboration

Donna L Mendrick 1 collaboration

Thomas Neumann 1 collaboration

Giorgia Pallocca 1 collaboration

Ivan Rusyn 1 collaboration

Lena Smirnova 1 collaboration

Thomas Steger-Hartmann 1 collaboration

Danilo A Tagle 1 collaboration

Sergej Tsyb 1 collaboration

Martin Trapecar 1 collaboration

Bob Van de Water 1 collaboration

Janny Van den Eijnden-van Raaij 1 collaboration

Paul Vulto 1 collaboration

Kengo Watanabe 1 collaboration

Armin Wolf 1 collaboration

Xiaobing Zhou 1 collaboration

Adrian Roth 1 collaboration

Tatjana Jankevic 1 collaboration

Ivan Gordeev 1 collaboration

Nikolay Lukoyanov 1 collaboration

Hiroyuki Watanabe 1 collaboration

Liliana S Carvalho 1 collaboration

Olga Kononenko 1 collaboration

Daniil Sarkisyan 1 collaboration

Mengliang Zhang 1 collaboration

Marlene Storm Andersen 1 collaboration

Elena A Lukoyanova 1 collaboration

Igor Bazov 1 collaboration

Tatiana Iakovleva 1 collaboration

Jens Schouenborg 1 collaboration

Marius Kemper 1 collaboration

Michael Tachezy 1 collaboration

Florian Gebauer 1 collaboration

Kristoffer Riecken 1 collaboration

Achim Aigner 1 collaboration

Jakob Izbicki 1 collaboration

Regina Shaykhutdinova 1 collaboration

Olga V Shcherbakova 1 collaboration

Yana V Serdyuk 1 collaboration

Savely A Sheetikov 1 collaboration

Ksenia V Zornikova 1 collaboration

Alexandra V Maleeva 1 collaboration

Alexandra Khmelevskaya 1 collaboration

Dmitry V Dianov 1 collaboration

Naina T Shakirova 1 collaboration

Dmitry B Malko 1 collaboration

Ekaterina Khamaganova 1 collaboration

Anton V Ershov 1 collaboration

Elena Y Osipova 1 collaboration

Ruslan V Nikolaev 1 collaboration

Dmitry E Pershin 1 collaboration

Viktoria A Vedmedskia 1 collaboration

Michael Maschan 1 collaboration

Victoria R Ginanova 1 collaboration

Grigory A Efimov 1 collaboration

Dmitriy Doroshenko 1 collaboration

Tom A P Driedonks 1 collaboration

Lyle H Nyberg 1 collaboration

Abigail Conte 1 collaboration

Zexu Ma 1 collaboration

Andrew Pekosz 1 collaboration

Eduard Duban 1 collaboration

Holger Sültmann 1 collaboration

Kenneth W Witwer 1 collaboration

Victor Zgoda 1 collaboration

Olga Tikhonova 1 collaboration

Barbara Burwinkel 1 collaboration

Jonas Bergquist 1 collaboration

Lidiia Astakhova 1 collaboration

Larisa Bolotina 1 collaboration

Andrei Kachmazov 1 collaboration

Anna Kudryavtseva 1 collaboration

Ildar Bakhtogarimov 1 collaboration

Irina Gaisina 1 collaboration

Maxim Topchiy 1 collaboration

Andrey Asachenko 1 collaboration

Boris Alekseev 1 collaboration

Yuri Ushkaryov 1 collaboration

Elena Stekolshchikova 1 collaboration

Anna Serkina 1 collaboration

Alexandra Razumovskaya 1 collaboration

Maria Silkina 1 collaboration

Ivan Antipenko 1 collaboration

Ekaterina Evtushenko 1 collaboration

Lu-Chun Chen 1 collaboration

Chang-Jiun Wu 1 collaboration

Che-Mai Chang 1 collaboration

Chin-Lin Guo 1 collaboration

Wei-Chiao Chang 1 collaboration

Dmitry Sakharov 1 collaboration

Sergey Shilin 1 collaboration

Irina Tsypina 1 collaboration

A Baranova 1 collaboration

D Maltseva 1 collaboration

Ksenia Kirdey 1 collaboration

Dmitriy Alekseev 1 collaboration

Sofya Lukashevich 1 collaboration

Ashot Nersisyan 1 collaboration

Cai Hui 1 collaboration

Svetlana Lebedeva 1 collaboration

Arus Margaryan 1 collaboration

Elena Smolyarchuk 1 collaboration

Andrey Nedorubov 1 collaboration

Maria Materenchuk 1 collaboration

Kerim Mutig 1 collaboration