Ales Machara

Affiliations

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, 166 10, Czech Republic.

Publications (12)

Evolution of Linoleic Acid Biosynthesis Paved the Way for Ecological Success of Termites.

Molecular biology and evolution

Avec: Stanislav Macháček , Michal Tupec , Natan Horáček , Martina Halmová , Amit Roy , Aleš Machara , Pavlína Kyjaková , Ondřej Lukšan , Iva Pichová , Robert Hanus

Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.

International journal of molecular sciences

Avec: Robert Reiberger , Kateřina Radilová , Michal Kráľ , Václav Zima , Pavel Majer , Jiří Brynda , Martin Dračínský , Jan Konvalinka , Milan Kožíšek , Aleš Machara

Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.

Antiviral research

Avec: Kateřina Radilová , Václav Zima , Michal Kráľ , Aleš Machara , Pavel Majer , Jan Hodek , Jan Weber , Jiří Brynda , Timotej Strmeň , Jan Konvalinka , Milan Kožíšek

structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.

Antiviral research

Avec: Jakub Hejdánek , Kateřina Radilová , Petr Pachl , Jan Hodek , Aleš Machara , Jan Weber , Pavlína Řezáčová , Jan Konvalinka , Milan Kožíšek

Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.

Bioorganic & medicinal chemistry

Avec: Václav Zima , Carlos Berenguer Albiñana , Kateřina Rojíková , Jana Pokorná , Petr Pachl , Pavlína Řezáčová , Jason Hudlicky , Václav Navrátil , Pavel Majer , Jan Konvalinka , Milan Kožíšek , Aleš Machara

Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the Cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica.

Insect biochemistry and molecular biology

Avec: Matej Milacek , Lenka Bittova , Sarka Tumova , Ondrej Luksan , Robert Hanus , Pavlina Kyjakova , Ales Marek , Marek Jindra

Characterization of Triacylglycerol Estolide Isomers Using High-Resolution Tandem Mass Spectrometry with Nanoelectrospray Ionization.

Biomolecules

Avec: Lukáš Cudlman , Aleš Machara , Vladimír Vrkoslav , Miroslav Polášek , Zuzana Bosáková , Stephen J Blanksby , Josef Cvačka

Putative ligand binding sites of two functionally characterized bark beetle odorant receptors.

BMC biology

Avec: Jothi K Yuvaraj , Rebecca E Roberts , Yonathan Sonntag , Xiao-Qing Hou , Ewald Grosse-Wilde , Aleš Machara , Dan-Dan Zhang , Bill S Hansson , Urban Johanson , Christer Löfstedt , Martin N Andersson

Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.

European journal of medicinal chemistry

Avec: Václav Zima , Kateřina Radilová , Milan Kožíšek , Carlos Berenguer Albiñana , Elena Karlukova , Jiří Brynda , Jindřich Fanfrlík , Miroslav Flieger , Jan Hodek , Jan Weber , Pavel Majer , Jan Konvalinka , Aleš Machara

Understanding desaturation/hydroxylation activity of castor stearoyl Δ

Computational and structural biotechnology journal

Avec: Michal Tupec , Martin Culka , Aleš Machara , Stanislav Macháček , Daniel Bím , Aleš Svatoš , Lubomír Rulíšek , Iva Pichová

Diketo-Ketoenol Tautomers in Curcuminoids: Synthesis, Separation of Tautomers, and Kinetic and Structural Studies.

The Journal of organic chemistry

Avec: Zuzana Osifová , Robert Reiberger , Ivana Císařová , Aleš Machara , Martin Dračínský

3'-Dehydroxypurpurogallin-4-carboxamides as Influenza A Endonuclease Inhibitors: Synthesis, SAR Analysis, and Structural Characterization of Protein Complex.

ChemMedChem

Avec: Michal Kral , Tomáš Kotačka , Robert Reiberger , Gabriela Panýrková , Kateřina Radilová , Zuzana Osifová , Miroslav Flieger , Jan Konvalinka , Pavel Majer , Milan Kožíšek

Réseau de co-auteurs

Aleš Machara 10 collaborations

Jan Konvalinka 6 collaborations

Milan Kožíšek 6 collaborations

Kateřina Radilová 5 collaborations

Pavel Majer 5 collaborations

Václav Zima 4 collaborations

Robert Reiberger 3 collaborations

Jiří Brynda 3 collaborations

Jan Hodek 3 collaborations

Jan Weber 3 collaborations

Stanislav Macháček 2 collaborations

Michal Tupec 2 collaborations

Iva Pichová 2 collaborations

Robert Hanus 2 collaborations

Michal Kráľ 2 collaborations

Martin Dračínský 2 collaborations

Petr Pachl 2 collaborations

Pavlína Řezáčová 2 collaborations

Carlos Berenguer Albiñana 2 collaborations

Miroslav Flieger 2 collaborations

Zuzana Osifová 2 collaborations

Natan Horáček 1 collaboration

Martina Halmová 1 collaboration

Amit Roy 1 collaboration

Pavlína Kyjaková 1 collaboration

Ondřej Lukšan 1 collaboration

Timotej Strmeň 1 collaboration

Jakub Hejdánek 1 collaboration

Kateřina Rojíková 1 collaboration

Jana Pokorná 1 collaboration

Jason Hudlicky 1 collaboration

Václav Navrátil 1 collaboration

Matej Milacek 1 collaboration

Lenka Bittova 1 collaboration

Sarka Tumova 1 collaboration

Ondrej Luksan 1 collaboration

Pavlina Kyjakova 1 collaboration

Ales Marek 1 collaboration

Marek Jindra 1 collaboration

Lukáš Cudlman 1 collaboration

Vladimír Vrkoslav 1 collaboration

Miroslav Polášek 1 collaboration

Zuzana Bosáková 1 collaboration

Stephen J Blanksby 1 collaboration

Josef Cvačka 1 collaboration

Jothi K Yuvaraj 1 collaboration

Rebecca E Roberts 1 collaboration

Yonathan Sonntag 1 collaboration

Xiao-Qing Hou 1 collaboration

Ewald Grosse-Wilde 1 collaboration

Dan-Dan Zhang 1 collaboration

Bill S Hansson 1 collaboration

Urban Johanson 1 collaboration

Christer Löfstedt 1 collaboration

Martin N Andersson 1 collaboration

Elena Karlukova 1 collaboration

Jindřich Fanfrlík 1 collaboration

Martin Culka 1 collaboration

Daniel Bím 1 collaboration

Aleš Svatoš 1 collaboration

Lubomír Rulíšek 1 collaboration

Ivana Císařová 1 collaboration

Michal Kral 1 collaboration

Tomáš Kotačka 1 collaboration

Gabriela Panýrková 1 collaboration