Mobile barrier mechanisms for Na


Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
25 Nov 2023
Historique:
pubmed: 4 10 2023
medline: 4 10 2023
entrez: 4 10 2023
Statut: epublish

Résumé

While many 3D structures of cation-coupled transporters have been determined, the mechanistic details governing the obligatory coupling and functional regulations still remain elusive. The bacterial melibiose transporter (MelB) is a prototype of the Na

Identifiants

pubmed: 37790566
doi: 10.1101/2023.09.18.558283
pmc: PMC10542114
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM122759
Pays : United States
Organisme : NIGMS NIH HHS
ID : U24 GM129541
Pays : United States

Références

Science. 2003 Aug 1;301(5633):616-20
pubmed: 12893936
Trends Microbiol. 1999 Apr;7(4):172-6
pubmed: 10217833
Nat Commun. 2014;5:3009
pubmed: 24389923
Nat Rev Drug Discov. 2015 Aug;14(8):543-60
pubmed: 26111766
Nature. 2013 Jul 18;499(7458):364-8
pubmed: 23770568
J Biol Chem. 2011 Feb 25;286(8):6367-74
pubmed: 21148559
J Gen Physiol. 2017 Nov 6;149(11):1029-1039
pubmed: 29054867
Nat Commun. 2022 Mar 10;13(1):1265
pubmed: 35273146
Nature. 2013 Apr 25;496(7446):533-6
pubmed: 23542591
J Gen Physiol. 2021 Aug 2;153(8):
pubmed: 34110360
Nature. 2005 Jun 30;435(7046):1197-202
pubmed: 15988517
Commun Biol. 2021 Aug 2;4(1):931
pubmed: 34341464
Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12148-52
pubmed: 15304639
Nature. 2005 Sep 8;437(7056):215-23
pubmed: 16041361
Philos Trans R Soc Lond B Biol Sci. 2009 Jan 27;364(1514):149-54
pubmed: 18977735
Cell. 2015 Jul 30;162(3):478-87
pubmed: 26232220
Mol Cell Proteomics. 2015 Oct;14(10):2833-47
pubmed: 26290498
J Biol Chem. 1993 Feb 15;268(5):3209-15
pubmed: 8428997
Nature. 1988 Mar 24;332(6162):323-7
pubmed: 3127726
Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2407-12
pubmed: 25675534
J Biol Chem. 2016 Feb 26;291(9):4453-61
pubmed: 26725230
Science. 2003 Aug 1;301(5633):610-5
pubmed: 12893935
BMC Biol. 2018 Aug 3;16(1):85
pubmed: 30075778
Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22078-83
pubmed: 21135207
Biochemistry. 1995 Apr 4;34(13):4412-20
pubmed: 7703254
Res Microbiol. 1990 Mar-Apr;141(3):286-9
pubmed: 2281191
J Bacteriol. 2014 Sep;196(17):3134-9
pubmed: 24957620
J Biol Chem. 1993 Feb 15;268(5):3216-21
pubmed: 8428998
J Chem Theory Comput. 2009 Aug 20;5(9):2353-2370
pubmed: 20161005
Biochem Biophys Res Commun. 2001 Jul 13;285(2):348-54
pubmed: 11444849
J Mol Biol. 1996 Jul 19;260(3):289-98
pubmed: 8757792
Nat Commun. 2017 Oct 13;8(1):923
pubmed: 29030554
Nature. 2007 Jan 25;445(7126):387-93
pubmed: 17230192
Nat Methods. 2020 Mar;17(3):328-334
pubmed: 32042190
Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):
pubmed: 34782475
Structure. 2023 Jan 5;31(1):58-67.e4
pubmed: 36525976
J Biol Chem. 2014 Nov 21;289(47):33012-9
pubmed: 25296751
Methods. 2012 Dec;58(4):325-34
pubmed: 22841567
Chem Rev. 2021 May 12;121(9):5289-5335
pubmed: 33886296
Nature. 2021 Aug;596(7873):583-589
pubmed: 34265844
Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1784-8
pubmed: 24453216
Acta Crystallogr D Struct Biol. 2018 Jun 1;74(Pt 6):545-559
pubmed: 29872005
Annu Rev Biophys Biomol Struct. 2006;35:67-91
pubmed: 16689628
Microbiol Mol Biol Rev. 2014 Jun;78(2):231-56
pubmed: 24847021
Science. 2007 Nov 23;318(5854):1258-65
pubmed: 17962520
J Comput Chem. 2008 Aug;29(11):1859-65
pubmed: 18351591
Mol Cell. 2009 Feb 27;33(4):528-36
pubmed: 19250913
Protein Expr Purif. 2021 Sep;185:105906
pubmed: 33991675
J Biol Chem. 1988 Sep 15;263(26):12909-15
pubmed: 3047112
Curr Opin Struct Biol. 2019 Oct;58:305-313
pubmed: 31351767
Cell. 1999 Apr 30;97(3):339-47
pubmed: 10319814
J Bacteriol. 2012 Oct;194(20):5538-44
pubmed: 22865849
Protein Eng. 2001 Dec;14(12):993-1000
pubmed: 11809930
J Biol Chem. 1992 Sep 15;267(26):18336-41
pubmed: 1526973
Nat Methods. 2019 Jul;16(7):595-602
pubmed: 31249422
J Biol Chem. 2023 Aug;299(8):104967
pubmed: 37380079
J Biol Chem. 2007 Mar 9;282(10):7066-76
pubmed: 17213193
Nat Methods. 2023 Jun;20(6):891-897
pubmed: 37106230
Biochemistry. 2011 Apr 19;50(15):3272-8
pubmed: 21410291
Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2126-32
pubmed: 15572765
Nat Methods. 2010 Dec;7(12):1003-8
pubmed: 21037590
Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2119436119
pubmed: 35549554
Nat Commun. 2020 Dec 2;11(1):6162
pubmed: 33268777
Curr Protoc Protein Sci. 2016 Nov 1;86:2.9.1-2.9.37
pubmed: 27801516
Chem Rev. 2017 Mar 22;117(6):4669-4713
pubmed: 28177242
J Biol Chem. 2006 Sep 8;281(36):25882-92
pubmed: 16822867
J Am Soc Mass Spectrom. 2018 Mar;29(3):623-629
pubmed: 29299838
J Biomol Tech. 2003 Sep;14(3):171-82
pubmed: 13678147
J Biol Chem. 2021 Sep;297(3):101090
pubmed: 34416232
Biochemistry. 2001 Nov 13;40(45):13744-52
pubmed: 11695924
J Phys Chem B. 2010 Jun 17;114(23):7830-43
pubmed: 20496934
J Chem Theory Comput. 2013 Jan 8;9(1):461-469
pubmed: 23316124
J Chem Theory Comput. 2012 Sep 11;8(9):3257-3273
pubmed: 23341755
Annu Rev Biophys. 2015;44:257-83
pubmed: 26098515
Sci Rep. 2015 Jan 28;5:8070
pubmed: 25627011
Sci Rep. 2022 Aug 2;12(1):13248
pubmed: 35918457
Protein Sci. 2018 Jan;27(1):14-25
pubmed: 28710774
J Mol Biol. 2022 Jun 30;434(12):167598
pubmed: 35461877
Biochemistry. 2009 Oct 6;48(39):9250-5
pubmed: 19719233
Microbiol Rev. 1993 Sep;57(3):543-94
pubmed: 8246840

Auteurs

Parameswaran Hariharan (P)

Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.

Yuqi Shi (Y)

Thermo Fisher Scientific, San Jose, CA 95134, USA.

Satoshi Katsube (S)

Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.

Katleen Willibal (K)

VIB-VUB Center for Structural Biology, 1050 Brussel, Belgium.

Nathan D Burrows (ND)

Division of CryoEM and Bioimaging, Stanford Synchrotron Radiation Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.

Patrick Mitchell (P)

Division of CryoEM and Bioimaging, Stanford Synchrotron Radiation Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.

Amirhossein Bakhtiiari (A)

Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.

Samantha Stanfield (S)

Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.

Els Pardon (E)

VIB-VUB Center for Structural Biology, 1050 Brussel, Belgium.

H Ronald Kaback (HR)

Department of Physiology, University of California, Los Angeles, Los Angeles, CA, USA.

Ruibin Liang (R)

Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.

Jan Steyaert (J)

VIB-VUB Center for Structural Biology, 1050 Brussel, Belgium.

Rosa Viner (R)

Thermo Fisher Scientific, San Jose, CA 95134, USA.

Lan Guan (L)

Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.

Classifications MeSH