Safety and efficacy of Vitamin D
clinical pharmacology
clinical trials
leukaemia
molecular aspects
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
29 08 2023
29 08 2023
Historique:
medline:
31
8
2023
pubmed:
30
8
2023
entrez:
29
8
2023
Statut:
epublish
Résumé
The study aimed to compare early molecular response (EMR) rates at 3 months of imatinib therapy with and without vitamin D Double-blind, placebo-controlled, exploratory randomised trial. Tertiary care hospital in northern India. Treatment-naive patients with chronic phase chronic myeloid leukaemia (n=62) aged >12 years were recruited from January 2020 to January 2021. Patients with progressive disease, pregnancy and hypercalcaemia were excluded. Oral vitamin D The primary outcome was to compare EMR (defined as At baseline, 14.5% of the patients had normal vitamin D Vitamin D CTRI/2019/09/021164.
Identifiants
pubmed: 37643857
pii: bmjopen-2022-066361
doi: 10.1136/bmjopen-2022-066361
pmc: PMC10465917
doi:
Substances chimiques
Imatinib Mesylate
8A1O1M485B
Cholecalciferol
1C6V77QF41
Types de publication
Randomized Controlled Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e066361Informations de copyright
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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