Cardiopulmonary exercise testing to indicate increased ventilatory variability in subjects with dysfunctional breathing.
dysfunctional breathing
dyspnoea
exercise test
hyperventilation
respiration
Journal
Clinical physiology and functional imaging
ISSN: 1475-097X
Titre abrégé: Clin Physiol Funct Imaging
Pays: England
ID NLM: 101137604
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
revised:
01
03
2023
received:
21
11
2022
accepted:
30
03
2023
medline:
8
8
2023
pubmed:
1
4
2023
entrez:
31
3
2023
Statut:
ppublish
Résumé
Dysfunctional breathing (DB) is a common, but largely underappreciated, cause of chronic dyspnoea. Under visual inspection, most subjects with DB present with larger sequential changes in ventilation (V̇E) and breathing pattern (tidal volume (VT) and breathing frequency (f)) before and/or during incremental cardiopulmonary exercise testing (CPET). Currently, however, there are no objective criteria to indicate increased ventilatory variability in these subjects. Twenty chronically dyspnoeic subjects with DB and 10 age- and sex-matched controls performed CPET on a cycle ergometer. Cut-offs to indicate increased V̇E, VT, f, and f/VT ratio variability (Δ = highest-lowest 20 s arithmetic mean) over the last resting minute ( Subjects with DB presented with increased V̇E, higher ventilatory variability, higher dyspnoea burden, and lower exercise capacity compared to controls (p < 0.05). ΔV̇E This study provides objective criteria to indicate increased ventilatory variability during incremental CPET in dyspnoeic subjects with DB. Large variability in breathing frequency seems particularly useful in this context, a finding that should be prospectively confirmed in larger studies.
Sections du résumé
BACKGROUND
BACKGROUND
Dysfunctional breathing (DB) is a common, but largely underappreciated, cause of chronic dyspnoea. Under visual inspection, most subjects with DB present with larger sequential changes in ventilation (V̇E) and breathing pattern (tidal volume (VT) and breathing frequency (f)) before and/or during incremental cardiopulmonary exercise testing (CPET). Currently, however, there are no objective criteria to indicate increased ventilatory variability in these subjects.
METHODS
METHODS
Twenty chronically dyspnoeic subjects with DB and 10 age- and sex-matched controls performed CPET on a cycle ergometer. Cut-offs to indicate increased V̇E, VT, f, and f/VT ratio variability (Δ = highest-lowest 20 s arithmetic mean) over the last resting minute (
RESULTS
RESULTS
Subjects with DB presented with increased V̇E, higher ventilatory variability, higher dyspnoea burden, and lower exercise capacity compared to controls (p < 0.05). ΔV̇E
CONCLUSIONS
CONCLUSIONS
This study provides objective criteria to indicate increased ventilatory variability during incremental CPET in dyspnoeic subjects with DB. Large variability in breathing frequency seems particularly useful in this context, a finding that should be prospectively confirmed in larger studies.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
305-312Subventions
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : 304061/2019-0
Organisme : Incentive Fund of Research (FIPE; Brazil) of Hospital de Clinicas de Porto Alegre
ID : 2018-0586
Informations de copyright
© 2023 Scandinavian Society of Clinical Physiology and Nuclear Medicine.
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