Molecular Mechanisms to Target Cellular Senescence in Aging and Disease.


Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
23 Nov 2022
Historique:
received: 18 11 2022
accepted: 21 11 2022
entrez: 11 12 2022
pubmed: 12 12 2022
medline: 15 12 2022
Statut: epublish

Résumé

Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, including DNA damage, increased cellular oxidative stress, telomere shortening, oncogene activation, and a deep epigenetic remodeling [...].

Identifiants

pubmed: 36496992
pii: cells11233732
doi: 10.3390/cells11233732
pmc: PMC9737399
pii:
doi:

Types de publication

Editorial

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Serena Marcozzi (S)

Advanced Technology Center for Aging Research, IRCCS INRCA, 60121 Ancona, Italy.
Scientific Direction, IRCCS INRCA, 60124 Ancona, Italy.

Antonio Paolo Beltrami (AP)

Institute of Clinical Pathology, Department of Medicine (DAME), University of Udine and Azienda Sanitaria Friuli Centrale (ASUFC), 33100 Udine, Italy.

Marco Malavolta (M)

Advanced Technology Center for Aging Research, IRCCS INRCA, 60121 Ancona, Italy.

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Classifications MeSH