Relationship between liver fat content and lifestyle factors in adults with metabolic syndrome.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
19 10 2022
19 10 2022
Historique:
received:
12
04
2022
accepted:
13
10
2022
entrez:
19
10
2022
pubmed:
20
10
2022
medline:
22
10
2022
Statut:
epublish
Résumé
The aim of this study was to investigate the associations between liver fat content (LFC), sedentary behaviour (SB), physical activity (PA), fitness, diet, body composition, and cardiometabolic risk factors in adults with metabolic syndrome. A total of 44 sedentary adults (mean age 58 [SD 7] years; 25 women) with overweight or obesity participated. LFC was assessed with magnetic resonance spectroscopy and imaging, SB and PA with hip-worn accelerometers (26 [SD 3] days), fitness by maximal bicycle ergometry, body composition by air displacement plethysmography and nutrient intake by 4-day food diaries. LFC was not independently associated with SB, PA or fitness. Adjusted for sex and age, LFC was associated with body fat%, body mass index, waist circumference, triglycerides, alanine aminotransferase, and with insulin resistance markers. There was and inverse association between LFC and daily protein intake, which persisted after further adjusment with body fat%. LFC is positively associated with body adiposity and cardiometabolic risk factors, and inversely with daily protein intake. SB, habitual PA or fitness are not independent modulators of LFC. However, as PA is an essential component of healthy lifestyle, it may contribute to liver health indirectly through its effects on body composition in adults with metabolic syndrome.
Identifiants
pubmed: 36261605
doi: 10.1038/s41598-022-22361-3
pii: 10.1038/s41598-022-22361-3
pmc: PMC9581946
doi:
Substances chimiques
Alanine Transaminase
EC 2.6.1.2
Triglycerides
0
Dietary Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
17428Informations de copyright
© 2022. The Author(s).
Références
BMJ Open. 2013 Jun 20;3(6):
pubmed: 23794543
Therap Adv Gastroenterol. 2017 Sep;10(9):701-713
pubmed: 28932271
BMJ Open. 2017 Mar 24;7(3):e011843
pubmed: 28341684
PLoS One. 2017 Jun 29;12(6):e0180119
pubmed: 28662164
Hepatology. 2008 Dec;48(6):1791-8
pubmed: 18972405
Am J Gastroenterol. 2011 Mar;106(3):460-8; quiz 469
pubmed: 21206486
Int J Environ Res Public Health. 2021 May 06;18(9):
pubmed: 34066552
Liver Int. 2009 Jan;29(1):82-8
pubmed: 18647235
Am J Clin Nutr. 2002 Mar;75(3):453-67
pubmed: 11864850
Hepatology. 2020 Nov;72(5):1556-1568
pubmed: 32012316
Nutrients. 2019 Dec 06;11(12):
pubmed: 31817648
J Hepatol. 2015 Nov;63(5):1229-37
pubmed: 26385766
Res Q Exerc Sport. 2000 Jun;71 Suppl 2:1-14
pubmed: 25680007
Front Nutr. 2021 Feb 16;8:640557
pubmed: 33665203
Diabetes Metab Syndr Obes. 2018 Sep 25;11:533-542
pubmed: 30288073
Clin Liver Dis (Hoboken). 2019 Apr 30;13(4):114-116
pubmed: 31061705
J Hepatol. 2018 May;68(5):1063-1075
pubmed: 29408694
PLoS One. 2014 Nov 26;9(11):e112574
pubmed: 25426708
Br J Sports Med. 2021 Nov;55(22):1277-1285
pubmed: 34006506
PLoS One. 2021 Oct 14;16(10):e0249501
pubmed: 34648504
Ann Med. 2005;37(5):347-56
pubmed: 16179270
Hepatology. 2016 Jul;64(1):73-84
pubmed: 26707365
Nat Rev Gastroenterol Hepatol. 2021 Apr;18(4):223-238
pubmed: 33349658
BMJ Open. 2016 Sep 08;6(9):e011939
pubmed: 27609847
Diagnostics (Basel). 2021 May 07;11(5):
pubmed: 34067193
J Obes. 2016;2016:2719014
pubmed: 27777796
Circulation. 2009 Oct 20;120(16):1640-5
pubmed: 19805654
Eur J Clin Nutr. 2021 Apr;75(4):588-601
pubmed: 33087892
J Aging Phys Act. 2012 Jul;20(3):332-44
pubmed: 22186833
Med Sci Sports Exerc. 2015 Aug;47(8):1727-34
pubmed: 25386715
BMJ Open. 2019 Mar 30;9(3):e026854
pubmed: 30928957
Eur J Prev Cardiol. 2019 Dec;26(2_suppl):33-46
pubmed: 31766917
Gastroenterology. 2006 Jun;130(7):2023-30
pubmed: 16762625
Eur J Public Health. 2018 Oct 1;28(5):944-950
pubmed: 29554269
Obes Rev. 2016 Jun;17(6):510-9
pubmed: 27020692
J Investig Med. 2017 Dec;65(8):1102-1115
pubmed: 28947639
Scand J Med Sci Sports. 2018 Mar;28(3):1092-1102
pubmed: 29144567
J Res Med Sci. 2016 Jul 29;21:53
pubmed: 27904598
Med Sci Sports Exerc. 2019 Jun;51(6):1169-1177
pubmed: 30694971
Hepatology. 2009 May;49(5):1537-44
pubmed: 19291789
Lancet Diabetes Endocrinol. 2014 Nov;2(11):901-10
pubmed: 24731669
Epidemiol Rev. 2007;29:77-87
pubmed: 17478441
Nat Med. 2018 Jul;24(7):908-922
pubmed: 29967350
Diabetes Care. 2007 Mar;30(3):683-8
pubmed: 17327341
J Sci Med Sport. 2021 Dec;24(12):1255-1260
pubmed: 34489177
PLoS One. 2015 Aug 20;10(8):e0134813
pubmed: 26292225
Sensors (Basel). 2010;10(8):7772-88
pubmed: 22163626