Sarcopenia in patients with diabetes mellitus.


Journal

Folia medica
ISSN: 1314-2143
Titre abrégé: Folia Med (Plovdiv)
Pays: Bulgaria
ID NLM: 2984761R

Informations de publication

Date de publication:
31 Aug 2022
Historique:
received: 23 01 2021
accepted: 13 05 2021
entrez: 31 8 2022
pubmed: 1 9 2022
medline: 9 9 2022
Statut: ppublish

Résumé

Diseases such as diabetes mellitus may be associated with adverse changes in body composition. Sarcopenia is characterized by a progressive and generalized loss of skeletal muscle mass and functionality. To investigate the relationship between type 2 diabetes mellitus (T2DM) and sarcopenia. In a retrospective, non-randomized study, 35 T2DM patients, aged 20-80 years, were assessed for sarcopenia prevalence compared to controls (n=16). Appendicular skeletal mass (ASM) (kg) was measured, and sarcopenia was defined as SMI <7.0 and <5.7 kg/m2, in males and females, respectively, using the European Working Group on Sarcopenia in Elderly (EWGOSP) definition. Low physical performance was defined as a walking speed of <0.8 m/s. Incidence of sarcopenia was significantly higher in T2DM patients vs. controls (27% vs. 20%, p=0.01) and elderly vs. young participants (40% vs. 12%, p<0.001), respectively. Walking velocity was significantly lower in T2DM patients compared to male and female controls (1.08±0.22 vs. 1.23±0.18 and 1.07±0.26 vs. 1.26±0.16, respectively, p<0.001,). A moderate prevalence of sarcopenia in patients with type 2 diabetes mellitus was observed, which appeared to increase significantly in older men. Finally, incidence of T2DM displayed decreased physical performance in both genders.

Identifiants

pubmed: 36045458
doi: 10.3897/folmed.64.e63530
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

596-601

Subventions

Organisme : Medical Research Council
ID : MR/P020941/1
Pays : United Kingdom

Informations de copyright

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Auteurs

Yannis Dionyssiotis (Y)

Spinal Cord Injury Rehabilitation Clinic, Patras University Hospital, Athens, Greece.

Panagiotis Athanassiou (P)

Rheumatology Department, Aghios Pavlos General Hospital, Thessaloniki, Greece.

Jannis Papathanasiou (J)

Medical University of Sofia, Sofia, Bulgaria.

Efstathios Efstathopoulos (E)

National and Kapodistrian University of Athens, Athens, Greece.

Konstantinos Prokopidis (K)

University of Liverpool, Liverpool, United Kingdom.

Georgios Trovas (G)

National and Kapodistrian University of Athens, Kifissia, Greece.

Ifigenia Kostoglou-Athanassiou (I)

Endocrinology Department, Asclepieio General Hospital, Voula, Greece.

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