Periodontal ligament fibroblasts-derived exosomes induced by PGE
Cell Differentiation
/ genetics
Cells, Cultured
Dinoprostone
/ metabolism
Exosomes
/ genetics
Extracellular Signal-Regulated MAP Kinases
/ metabolism
Fibroblasts
/ metabolism
Humans
Matrix Attachment Region Binding Proteins
/ metabolism
MicroRNAs
/ genetics
Osteogenesis
/ genetics
Periodontal Ligament
/ metabolism
Stem Cells
Transcription Factors
/ metabolism
Exosome
MiR-34c-5p
MicroRNA sequencing
Osteogenic differentiation
Periodontal ligament stem cells
Journal
Experimental cell research
ISSN: 1090-2422
Titre abrégé: Exp Cell Res
Pays: United States
ID NLM: 0373226
Informations de publication
Date de publication:
15 10 2022
15 10 2022
Historique:
received:
10
04
2022
revised:
01
08
2022
accepted:
08
08
2022
pubmed:
19
8
2022
medline:
14
9
2022
entrez:
18
8
2022
Statut:
ppublish
Résumé
Several studies have confirmed that exosomes containing microRNAs (miRNAs) from the aseptic inflammatory microenvironment play an important role in bone remodeling. But the mechanism that induces changes in the osteogenic ability of periodontal ligament stem cells (PDLSCs) is still unclear. In the present study, the osteogenic function of periodontal ligament fibroblasts-derived exosomes induced by PGE
Identifiants
pubmed: 35981635
pii: S0014-4827(22)00311-1
doi: 10.1016/j.yexcr.2022.113318
pii:
doi:
Substances chimiques
Matrix Attachment Region Binding Proteins
0
MicroRNAs
0
SATB2 protein, human
0
Transcription Factors
0
Extracellular Signal-Regulated MAP Kinases
EC 2.7.11.24
Dinoprostone
K7Q1JQR04M
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
113318Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest No competing interest exists.