A Regulatory Axis between Epithelial Splicing Regulatory Proteins and Estrogen Receptor α Modulates the Alternative Transcriptome of Luminal Breast Cancer.
EMT splicing signature
ESRP1
ESRP2
Rac1
Rac1b
alternative splicing
breast cancer
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
16 Jul 2022
16 Jul 2022
Historique:
received:
27
06
2022
revised:
13
07
2022
accepted:
14
07
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
29
7
2022
Statut:
epublish
Résumé
Epithelial splicing regulatory proteins 1 and 2 (ESRP1/2) control the splicing pattern during epithelial to mesenchymal transition (EMT) in a physiological context and in cancer, including breast cancer (BC). Here, we report that
Identifiants
pubmed: 35887187
pii: ijms23147835
doi: 10.3390/ijms23147835
pmc: PMC9319905
pii:
doi:
Substances chimiques
Estrogen Receptor alpha
0
RNA-Binding Proteins
0
Transcription Factors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Italian Association for Cancer Research
ID : IG15600
Organisme : Fondazione CRT
ID : 2017.0823
Organisme : University of Turin
ID : 2019 Local Research funding
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