Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
19 07 2022
Historique:
entrez: 21 7 2022
pubmed: 22 7 2022
medline: 26 7 2022
Statut: ppublish

Résumé

Background Excess visceral adiposity is associated with increased risk of cardiometabolic disorders. Short-term well-controlled clinical trials suggest that regular avocado consumption favorably affects body weight, visceral adiposity, and satiety. Methods and Results The HAT Trial (Habitual Diet and Avocado Trial) was a multicenter, randomized, controlled parallel-arm trial designed to test whether consuming 1 large avocado per day for 6 months in a diverse group of free-living individuals (N=1008) with an elevated waist circumference compared with a habitual diet would decrease visceral adiposity as measured by magnetic resonance imaging. Secondary and additional end points related to risk factors associated with cardiometabolic disorders were assessed. The primary outcome, change in visceral adipose tissue volume during the intervention period, was not significantly different between the Avocado Supplemented and Habitual Diet Groups (estimated mean difference (0.017 L [-0.024 L, 0.058 L],

Identifiants

pubmed: 35861827
doi: 10.1161/JAHA.122.025657
pmc: PMC9707833
doi:

Substances chimiques

Cholesterol, HDL 0
Cholesterol, LDL 0

Banques de données

ClinicalTrials.gov
['NCT03528031']

Types de publication

Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e025657

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Auteurs

Alice H Lichtenstein (AH)

JM USDA Human Nutrition Center on Aging, Tufts University Boston MA.

Penny M Kris-Etherton (PM)

Department of Nutritional Sciences Pennsylvania State University State College PA.

Kristina S Petersen (KS)

Department of Nutritional Sciences Texas Tech University Lubbock TX.

Nirupa R Matthan (NR)

JM USDA Human Nutrition Center on Aging, Tufts University Boston MA.

Samuel Barnes (S)

Department of Radiology Loma Linda University School of Medicine Loma Linda CA.

Mara Z Vitolins (MZ)

Department of Epidemiology and Prevention Wake Forest University School of Medicine Winston-Salem NC.

Zhaoping Li (Z)

Center for Human Nutrition David Geffen School of Medicine at UCLA Los Angeles CA.

Joan Sabaté (J)

Healthy Lifestyles, and Disease Prevention Loma Linda University School of Public Health Center for Nutrition Loma Linda CA.

Sujatha Rajaram (S)

Healthy Lifestyles, and Disease Prevention Loma Linda University School of Public Health Center for Nutrition Loma Linda CA.

Shilpy Chowdhury (S)

Department of Radiology Loma Linda University School of Medicine Loma Linda CA.

Kristin M Davis (KM)

Department of Behavioral Health Pennsylvania State University State College PA.

Jean Galluccio (J)

JM USDA Human Nutrition Center on Aging, Tufts University Boston MA.

Cheryl H Gilhooly (CH)

JM USDA Human Nutrition Center on Aging, Tufts University Boston MA.

Richard S Legro (RS)

Penn State College of Medicine Hershey PA.

Jason Li (J)

Center for Human Nutrition David Geffen School of Medicine at UCLA Los Angeles CA.

Laura Lovato (L)

Department of Biostatistics Wake Forest University School of Medicine Winston-Salem NC.

Letitia H Perdue (LH)

Department of Biostatistics Wake Forest University School of Medicine Winston-Salem NC.

Gayle Petty (G)

JM USDA Human Nutrition Center on Aging, Tufts University Boston MA.

Anna M Rasmussen (AM)

Center for Human Nutrition David Geffen School of Medicine at UCLA Los Angeles CA.

Gina Segovia-Siapco (G)

Healthy Lifestyles, and Disease Prevention Loma Linda University School of Public Health Center for Nutrition Loma Linda CA.

Rawiwan Sirirat (R)

Healthy Lifestyles, and Disease Prevention Loma Linda University School of Public Health Center for Nutrition Loma Linda CA.

April Sun (A)

Center for Human Nutrition David Geffen School of Medicine at UCLA Los Angeles CA.

David M Reboussin (DM)

Department of Biostatistics Wake Forest University School of Medicine Winston-Salem NC.

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Classifications MeSH