Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series.
Journal
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
ISSN: 1806-3756
Titre abrégé: J Bras Pneumol
Pays: Brazil
ID NLM: 101222274
Informations de publication
Date de publication:
2022
2022
Historique:
received:
25
10
2021
accepted:
19
02
2022
entrez:
4
5
2022
pubmed:
5
5
2022
medline:
7
5
2022
Statut:
epublish
Résumé
This brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who presented with persistent dyspnea within 4-15 months of discharge. We performed transbronchial biopsies, and the histopathological pattern consistently demonstrated peribronchial remodeling with interstitial pulmonary fibrosis. Therefore, lung biopsy may be useful in the approach of patients with long COVID-19, although the type of procedure, its precise indication, and the moment to perform it are yet to be clarified. (Brazilian Registry of Clinical Trials-ReBEC; identifier: RBR-8j9kqy [http://www.ensaiosclinicos.gov.br]).
Identifiants
pubmed: 35508067
pii: S1806-37132022000300300
doi: 10.36416/1806-3756/e20210438
pmc: PMC9064656
pii:
doi:
Types de publication
Journal Article
Langues
eng
por
Sous-ensembles de citation
IM
Pagination
e20210438Commentaires et corrections
Type : CommentIn
Références
Histopathology. 2021 Mar;78(4):542-555
pubmed: 32926596
Respiration. 2021;100(6):488-498
pubmed: 33725700
Thorax. 2013 Aug;68 Suppl 1:i1-i44
pubmed: 23860341
J Bras Pneumol. 2021 Sep 06;47(4):e20210213
pubmed: 34495179
Histopathology. 2020 Aug;77(2):169-172
pubmed: 32881045
Eur J Clin Invest. 2021 Jan;51(1):e13443
pubmed: 33131070
Respir Res. 2021 Jul 9;22(1):203
pubmed: 34243776
Lancet Respir Med. 2021 Jul;9(7):747-754
pubmed: 33964245
Expert Rev Respir Med. 2021 Jun;15(6):791-803
pubmed: 33902377
Mod Pathol. 2020 Nov;33(11):2128-2138
pubmed: 32572155
J Clin Pathol. 2020 Jul 28;:
pubmed: 32723800
Lancet Respir Med. 2020 Aug;8(8):807-815
pubmed: 32422178
Am J Clin Pathol. 2021 Mar 15;155(4):506-514
pubmed: 33316056
Sci Transl Med. 2020 Dec 16;12(574):
pubmed: 33257409
J Crit Care. 2020 Oct;59:149-155
pubmed: 32674001