Outcomes of 2-octyl cyanoacrylate skin adhesives following musculoskeletal oncology surgery: A STROBE-compliant observational study.


Journal

Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R

Informations de publication

Date de publication:
17 Dec 2021
Historique:
received: 20 08 2021
accepted: 28 11 2021
entrez: 17 12 2021
pubmed: 18 12 2021
medline: 15 2 2022
Statut: ppublish

Résumé

2-octyl cyanoacrylate (2OCA) is a high-viscosity medical-grade tissue adhesive that is routinely used. However, no studies have evaluated its use in musculoskeletal surgery.We enrolled 99 patients who underwent musculoskeletal surgery. 2OCA was chosen for wound closure and was performed by a specific surgeon for all patients. The drying times for the adhesive were recorded, and photographs were obtained intra-operatively. Posttreatment follow-up consisted of queries regarding pain level and recording incisional dehiscence, wound infection, hematoma, and incisional bleeding. Data collection was performed postoperatively at 48 hours, 5 to 10 days, 14 days, and 30 days. Other adverse events were documented.2OCA was applied to 110 incisions in 99 patients, comprising 62 female and 37 male patients. The mean age of patients was 50.41 (±16.83) years; mean incision length was 10.24 (±5.7) cm, and the mean pain score using a visual analogue scale was 2.37 on a postoperative day 7. The mean drying time was 1.81 (±0.59) minutes; 91 (91%) patients reported excellent and superior satisfaction, and the remaining patients reported "good" (6%) and "fair" (2%) satisfaction. The percentages of dehiscence, hematoma and keloid formation were considerably low.In this study, 2OCA was safe for musculoskeletal oncology surgical incisions. The incidence of postoperative adverse events was low. However, some patients develop hematomas. Postoperative pain was low, and patient satisfaction was high. 2OCA can be a practical alternative to traditional suture closure for skin incisions after musculoskeletal surgery.

Identifiants

pubmed: 34918713
doi: 10.1097/MD.0000000000028326
pii: 00005792-202112170-00088
pmc: PMC8678018
doi:

Substances chimiques

Cyanoacrylates 0
Tissue Adhesives 0
octyl 2-cyanoacrylate 6C655P1XVG

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e28326

Informations de copyright

Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

Déclaration de conflit d'intérêts

The authors have no funding and conflicts of interest to disclose.

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Auteurs

Thanapon Chobpenthai (T)

Princess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
Department of Orthopaedic Surgery, Chulabhorn Hospital, Bangkok, Thailand.

Thanate Poosiripinyo (T)

Department of Orthopaedics, Khon Kaen Hospital, Khon Kaen, Thailand.

Pakjai Tuntarattanapong (P)

Department of Orthopaedics, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

Pichaya Thanindratarn (P)

Department of Orthopaedic Surgery, Chulabhorn Hospital, Bangkok, Thailand.

Warayos Trathitephun (W)

Department of Orthopaedic Surgery, Chulabhorn Hospital, Bangkok, Thailand.

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