Role of Interleukin-1 Receptor-Like 1 (ST2) in Cerebrovascular Disease.
Brain edema
Inflammation
Soluble ST2
Stroke
Journal
Neurocritical care
ISSN: 1556-0961
Titre abrégé: Neurocrit Care
Pays: United States
ID NLM: 101156086
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
17
02
2021
accepted:
21
05
2021
pubmed:
8
7
2021
medline:
4
3
2022
entrez:
7
7
2021
Statut:
ppublish
Résumé
Following both ischemic and hemorrhagic stroke, innate immune cells initiate a proinflammatory response that further exacerbate tissue injury in the acute phase, but these cells also play an important reparative role thereafter. Numerous cytokines and signaling pathways have been implicated in driving the deleterious proinflammatory response, but less is known about the mediators that connect the initial vascular injury to the systemic immune response and the relationship between proinflammatory and reparative immune responses. The Interleukin-33 (IL-33) and serum stimulation-2 (ST2) axis is an interleukin signaling pathway that is a prime candidate to fulfill this role. In this review, we describe the biology of the IL-33/ST2 system, present evidence that its soluble decoy receptor, soluble ST2 (sST2), plays a key role in secondary neurologic injury after stroke, and discuss this in the context of the known role of IL-33/ST2 in other disease.
Identifiants
pubmed: 34231185
doi: 10.1007/s12028-021-01284-3
pii: 10.1007/s12028-021-01284-3
pmc: PMC8805653
mid: NIHMS1773727
doi:
Substances chimiques
Cytokines
0
Interleukin-1 Receptor-Like 1 Protein
0
Receptors, Interleukin-1
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
887-893Subventions
Organisme : NINDS NIH HHS
ID : K23 NS112474
Pays : United States
Organisme : NINDS NIH HHS
ID : R21 NS120002
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS099209
Pays : United States
Organisme : NINDS NIH HHS
ID : L30 NS097948
Pays : United States
Informations de copyright
© 2021. Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society.
Références
Stroke. 2010 Oct;41(10):2391-5
pubmed: 20798370
Nat Immunol. 2016 Feb;17(2):122-31
pubmed: 26784265
Int J Obes (Lond). 2013 May;37(5):658-65
pubmed: 22828942
Biochem Biophys Rep. 2015 Nov 21;5:8-15
pubmed: 28955802
Eur J Immunol. 2012 Jul;42(7):1804-14
pubmed: 22585447
Nat Immunol. 2004 Apr;5(4):373-9
pubmed: 15004556
Cytokine. 2017 Dec;100:1-10
pubmed: 28687373
Nat Neurosci. 2017 Feb;20(2):136-144
pubmed: 28092660
Curr Mol Med. 2019;19(5):357-363
pubmed: 30950351
Pharmacol Ther. 2011 Aug;131(2):179-86
pubmed: 21356240
J Neuroimmunol. 2019 Aug 15;333:576970
pubmed: 31146104
Immunity. 2005 Nov;23(5):479-90
pubmed: 16286016
Circulation. 2003 Feb 11;107(5):721-6
pubmed: 12578875
Nat Rev Neurol. 2014 Jan;10(1):44-58
pubmed: 24323051
J Leukoc Biol. 2020 Apr;107(4):663-671
pubmed: 32017227
Brain Res. 2015 Feb 9;1597:86-94
pubmed: 25500143
J Interferon Cytokine Res. 2014 Mar;34(3):162-8
pubmed: 24102578
J Allergy Clin Immunol. 2014 Jul;134(1):170-7
pubmed: 24568840
World J Gastroenterol. 2011 May 7;17(17):2181-90
pubmed: 21633527
Eur J Neurol. 2020 Nov;27(11):2202-2208
pubmed: 32593220
J Neurosci. 2017 May 3;37(18):4692-4704
pubmed: 28389473
J Immunol. 2009 Nov 15;183(10):6469-77
pubmed: 19841166
Blood. 2015 Jan 1;125(1):199-205
pubmed: 25377785
Ann Neurol. 2019 Sep;86(3):384-394
pubmed: 31291030
Neuron. 2010 Jul 29;67(2):181-98
pubmed: 20670828
Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1;308(7):L619-27
pubmed: 25595648
Curr Allergy Asthma Rep. 2013 Jun;13(3):271-80
pubmed: 23563812
JCI Insight. 2019 Mar 21;4(6):
pubmed: 30779711
Nat Med. 2011 Jul 07;17(7):796-808
pubmed: 21738161
Proc Natl Acad Sci U S A. 1989 Aug;86(15):5708-12
pubmed: 2527364
Neuron. 2015 Feb 18;85(4):703-9
pubmed: 25661185
Neurosci Lett. 1991 Apr 29;125(2):110-2
pubmed: 1881586
Ann Clin Transl Neurol. 2017 Jul 05;4(8):553-563
pubmed: 28812045
Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32679-32690
pubmed: 33293423
Cardiovasc Res. 2010 Sep 1;87(4):769-77
pubmed: 20363761
J Neuroimmunol. 2007 Mar;184(1-2):53-68
pubmed: 17188755
Stroke. 2020 Apr;51(4):1128-1134
pubmed: 32156203
J Immunol. 2009 Oct 15;183(8):5094-103
pubmed: 19801525
Mol Neurobiol. 2017 Jul;54(5):3879-3892
pubmed: 27405469
EMBO J. 1994 Mar 1;13(5):1176-88
pubmed: 8131748
Stroke. 2011 Jun;42(6):1781-6
pubmed: 21527759
Eur J Immunol. 2011 Mar;41(3):760-72
pubmed: 21308681
J Biomed Sci. 2018 Jul 12;25(1):56
pubmed: 30001716
FEBS Lett. 1989 Dec 4;258(2):301-4
pubmed: 2532153
JCI Insight. 2020 Apr 23;5(8):
pubmed: 32324168
Lancet Neurol. 2006 Jan;5(1):53-63
pubmed: 16361023
Inflamm Bowel Dis. 2010 Jul;16(7):1097-107
pubmed: 20014018
Immunol Rev. 2018 Jan;281(1):154-168
pubmed: 29247993
Nat Rev Immunol. 2010 Dec;10(12):826-37
pubmed: 21088683
Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):8017-22
pubmed: 20385815
Circulation. 2002 Dec 3;106(23):2961-6
pubmed: 12460879
Exp Neurol. 2020 Jun;328:113233
pubmed: 32044328
Blood. 2009 Oct 1;114(14):3117-26
pubmed: 19661270
J Clin Neurophysiol. 2005 Apr;22(2):92-8
pubmed: 15805808
Nature. 2019 Jan;565(7738):246-250
pubmed: 30602786
Int J Prev Med. 2017 Aug 31;8:65
pubmed: 28966754
N Engl J Med. 2013 Aug 8;369(6):529-39
pubmed: 23924003
Eur Heart J. 2012 Jul;33(14):1787-847
pubmed: 22611136
Brain Behav. 2019 Sep;9(9):e01369
pubmed: 31397082
Brain Behav Immun. 2015 Oct;49:322-36
pubmed: 26111431
Nat Rev Neurol. 2015 Feb;11(2):111-22
pubmed: 25623787
Nature. 2014 Sep 25;513(7519):564-568
pubmed: 25043027
Eur J Immunol. 2009 Apr;39(4):1046-55
pubmed: 19266498
J Cereb Blood Flow Metab. 1999 Aug;19(8):819-34
pubmed: 10458589