RAP1 moonlights to activate NF-κB and Notch in ALT.

NF-kappa B / genetics Telomerase / genetics Telomere / metabolism Telomere Homeostasis

Journal

Science signaling
ISSN: 1937-9145
Titre abrégé: Sci Signal
Pays: United States
ID NLM: 101465400

Informations de publication

Date de publication:
29 06 2021
Historique:
entrez: 30 6 2021
pubmed: 1 7 2021
medline: 15 1 2022
Statut: epublish

Résumé

Cancer cells activate either telomerase or telomere recombination (ALT) to maintain telomere length and achieve immortalization. In this issue of

Identifiants

DOI: 10.1126/scisignal.abj1166 PMID: 34187904
pubmed: 34187904
pii: 14/689/eabj1166
doi: 10.1126/scisignal.abj1166
pii:
doi:

Substances chimiques

NF-kappa B 0
Telomerase EC 2.7.7.49

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review Comment

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Auteurs

Dmitri Churikov (D)

Marseille Cancer Research Centre (CRCM), U1068 INSERM, UMR7258 CNRS, UM105 Aix-Marseille University, Institut Paoli-Calmettes, 13273 Marseille, France.
Ligue Nationale Contre le Cancer (Equipe labellisée), 75103 Paris, France.
ORCID: 0000-0003-1127-8852

Vincent Géli (V)

Marseille Cancer Research Centre (CRCM), U1068 INSERM, UMR7258 CNRS, UM105 Aix-Marseille University, Institut Paoli-Calmettes, 13273 Marseille, France. vincent.geli@inserm.fr.
Ligue Nationale Contre le Cancer (Equipe labellisée), 75103 Paris, France.
ORCID: 0000-0002-4103-7462

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Classifications MeSH

Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteur de transcription NF-kappa B › RAP1 moonlights to activate NF-κB and Notch in ALT.
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines de liaison à l'ARN › Ribonucléoprotéines › Telomerase › RAP1 moonlights to activate NF-κB and Notch in ALT.
Recherchemedicale.com › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Télomère › RAP1 moonlights to activate NF-κB and Notch in ALT.
Recherchemedicale.com › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Division cellulaire › Homéostasie des télomères › RAP1 moonlights to activate NF-κB and Notch in ALT.