Abdominal ultrasound findings contribute to a multivariable predictive risk score for surgical necrotizing enterocolitis: A pilot study.


Journal

American journal of surgery
ISSN: 1879-1883
Titre abrégé: Am J Surg
Pays: United States
ID NLM: 0370473

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 20 01 2021
revised: 04 04 2021
accepted: 19 04 2021
pubmed: 8 5 2021
medline: 22 12 2021
entrez: 7 5 2021
Statut: ppublish

Résumé

Abdominal ultrasound (AUS) is a promising adjunct to abdominal x-ray (AXR) for evaluating necrotizing enterocolitis (NEC). We developed a multivariable risk score incorporating AUS to predict surgical NEC. 83 patients were evaluated by AXR and AUS for suspected NEC. A subset had surgical NEC. Multivariate logistic regression determined predictors of surgical NEC, which were incorporated into a risk score. 14/83 patients (16.9%) had surgical NEC. 10/83 (12.0%) patients required acute intervention, while 4/83 (4.8%) patients only required delayed surgery. Four predictors of surgical NEC were identified: abdominal wall erythema (OR: 8.2, p = 0.048), portal venous gas on AXR (OR: 29.8, p = 0.014), and echogenic free fluid (OR: 17.2, p = 0.027) and bowel wall thickening (OR: 12.5, p = 0.030) on AUS. A multivariable risk score incorporating these predictors had excellent area-under-the-curve of 0.937 (95% CI: 0.879-0.994). AUS, as an adjunct to physical exam and AXR, has utility for predicting surgical NEC.

Sections du résumé

BACKGROUND BACKGROUND
Abdominal ultrasound (AUS) is a promising adjunct to abdominal x-ray (AXR) for evaluating necrotizing enterocolitis (NEC). We developed a multivariable risk score incorporating AUS to predict surgical NEC.
METHODS METHODS
83 patients were evaluated by AXR and AUS for suspected NEC. A subset had surgical NEC. Multivariate logistic regression determined predictors of surgical NEC, which were incorporated into a risk score.
RESULTS RESULTS
14/83 patients (16.9%) had surgical NEC. 10/83 (12.0%) patients required acute intervention, while 4/83 (4.8%) patients only required delayed surgery. Four predictors of surgical NEC were identified: abdominal wall erythema (OR: 8.2, p = 0.048), portal venous gas on AXR (OR: 29.8, p = 0.014), and echogenic free fluid (OR: 17.2, p = 0.027) and bowel wall thickening (OR: 12.5, p = 0.030) on AUS. A multivariable risk score incorporating these predictors had excellent area-under-the-curve of 0.937 (95% CI: 0.879-0.994).
CONCLUSIONS CONCLUSIONS
AUS, as an adjunct to physical exam and AXR, has utility for predicting surgical NEC.

Identifiants

pubmed: 33958200
pii: S0002-9610(21)00275-0
doi: 10.1016/j.amjsurg.2021.04.025
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1034-1039

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Stefanie P Lazow (SP)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: slazow@bidmc.harvard.edu.

Sarah A Tracy (SA)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: stracy@bidmc.harvard.edu.

Steven J Staffa (SJ)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: steven.staffa@childrens.harvard.edu.

Judy A Estroff (JA)

Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: judy.estroff@childrens.harvard.edu.

Richard B Parad (RB)

Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: rparad@bwh.harvard.edu.

Ilse M Castro-Aragon (IM)

Department of Radiology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA. Electronic address: ilse.castro-aragon@bmc.org.

Alan M Fujii (AM)

Department of Pediatrics, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA. Electronic address: alan.fujii@steward.org.

David Zurakowski (D)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: david.zurakowski@childrens.harvard.edu.

Catherine Chen (C)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: catherine.chen@childrens.harvard.edu.

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