Overview of CAPICE-Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe-an EU Marie Skłodowska-Curie International Training Network.
Anxiety
Attention deficit hyperactivity disorder (ADHD)
Childhood and adolescence psychopathology
Depression
Psychiatric genetics
Journal
European child & adolescent psychiatry
ISSN: 1435-165X
Titre abrégé: Eur Child Adolesc Psychiatry
Pays: Germany
ID NLM: 9212296
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
27
09
2019
accepted:
21
12
2020
pubmed:
22
1
2021
medline:
1
6
2022
entrez:
21
1
2021
Statut:
ppublish
Résumé
The Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER) identified child and adolescent mental illness as a priority area for research. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) is a European Union (EU) funded training network aimed at investigating the causes of individual differences in common childhood and adolescent psychopathology, especially depression, anxiety, and attention deficit hyperactivity disorder. CAPICE brings together eight birth and childhood cohorts as well as other cohorts from the EArly Genetics and Life course Epidemiology (EAGLE) consortium, including twin cohorts, with unique longitudinal data on environmental exposures and mental health problems, and genetic data on participants. Here we describe the objectives, summarize the methodological approaches and initial results, and present the dissemination strategy of the CAPICE network. Besides identifying genetic and epigenetic variants associated with these phenotypes, analyses have been performed to shed light on the role of genetic factors and the interplay with the environment in influencing the persistence of symptoms across the lifespan. Data harmonization and building an advanced data catalogue are also part of the work plan. Findings will be disseminated to non-academic parties, in close collaboration with the Global Alliance of Mental Illness Advocacy Networks-Europe (GAMIAN-Europe).
Identifiants
pubmed: 33474652
doi: 10.1007/s00787-020-01713-2
pii: 10.1007/s00787-020-01713-2
pmc: PMC9142454
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
829-839Subventions
Organisme : Medical Research Council
ID : MR/M021475/1
Pays : United Kingdom
Organisme : H2020 Marie Skłodowska-Curie Actions
ID : 721567
Organisme : Medical Research Council
ID : MR/S019669/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00011/7
Pays : United Kingdom
Organisme : Medical Research Council
ID : G19/2
Pays : United Kingdom
Informations de copyright
© 2021. The Author(s).
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