Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α-Amino Acids and DNA-Conjugated Carbonyls.

Amino Alcohols / chemical synthesis Catalysis Cyclization DNA / chemistry Ketones / chemistry Molecular Structure Oxidation-Reduction

Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
18 12 2020
Historique:
pubmed: 11 11 2020
medline: 17 8 2021
entrez: 10 11 2020
Statut: ppublish

Résumé

We report a DNA-compatible photoredox decarboxylative coupling of α-amino acids with carbonyl compounds to access DNA-encoded sp

Identifiants

DOI: 10.1021/acs.orglett.0c03461 PMID: 33170713
pubmed: 33170713
doi: 10.1021/acs.orglett.0c03461
doi:

Substances chimiques

Amino Alcohols 0
DNA-aldehydes 0
Ketones 0
DNA 9007-49-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

9484-9489

Auteurs

Huanan Wen (H)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Rui Ge (R)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Yi Qu (Y)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Jialin Sun (J)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Xiaodong Shi (X)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Weiren Cui (W)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Hao Yan (H)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Qi Zhang (Q)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Yulong An (Y)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Wenji Su (W)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Hongfang Yang (H)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Letian Kuai (L)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Alexander L Satz (AL)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
ORCID: 0000-0003-1284-1977

Xuanjia Peng (X)

WuXi AppTec (Shanghai) Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
ORCID: 0000-0001-6067-0311

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Classifications MeSH

Recherchemedicale.com › Composés chimiques organiques › Amines › Aminoalcools › Synthesis of 1,2-Amino Alcohols by...
Recherchemedicale.com › Phénomènes chimiques › Catalyse › Synthesis of 1,2-Amino Alcohols by...
Recherchemedicale.com › Métabolisme › Cyclisation › Synthesis of 1,2-Amino Alcohols by...
Recherchemedicale.com › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Synthesis of 1,2-Amino Alcohols by...
Recherchemedicale.com › Composés chimiques organiques › Cétones › Synthesis of 1,2-Amino Alcohols by...
Recherchemedicale.com › Phénomènes chimiques › Structure moléculaire › Synthesis of 1,2-Amino Alcohols by...
Recherchemedicale.com › Métabolisme › Métabolisme énergétique › Oxydoréduction › Synthesis of 1,2-Amino Alcohols by...