Leptin modulates pancreatic β-cell membrane potential through Src kinase-mediated phosphorylation of NMDA receptors.


Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
11 12 2020
Historique:
received: 03 08 2020
revised: 08 10 2020
pubmed: 11 10 2020
medline: 17 3 2021
entrez: 10 10 2020
Statut: ppublish

Résumé

The adipocyte-derived hormone leptin increases trafficking of K

Identifiants

pubmed: 33037073
pii: S0021-9258(17)50616-X
doi: 10.1074/jbc.RA120.015489
pmc: PMC7863909
pii:
doi:

Substances chimiques

LEP protein, human 0
Leptin 0
NR2B NMDA receptor 0
Receptors, N-Methyl-D-Aspartate 0
src-Family Kinases EC 2.7.10.2
N-methyl D-aspartate receptor subtype 2A VH92ICR8HX

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

17281-17297

Subventions

Organisme : NIH HHS
ID : P51 OD011092
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK057699
Pays : United States

Informations de copyright

© 2020 Cochrane et al.

Déclaration de conflit d'intérêts

Conflict of interest—The authors declare that they have no conflicts of interest with the contents of this article.

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Auteurs

Veronica A Cochrane (VA)

Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA.

Yi Wu (Y)

Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA.

Zhongying Yang (Z)

Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA.

Assmaa ElSheikh (A)

Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA; Department of Medical Biochemistry, Tanta University, Tanta, Egypt.

Jeremy Dunford (J)

Department of Integrated Physiology and Neuroscience, College of Arts and Sciences, Washington State University, Vancouver, Washington, USA.

Paul Kievit (P)

Division of Cardiometabolic Health, Oregon National Primate Research Center, Beaverton, Oregon, USA.

Dale A Fortin (DA)

Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA; Department of Integrated Physiology and Neuroscience, College of Arts and Sciences, Washington State University, Vancouver, Washington, USA. Electronic address: dale.fortin@wsu.edu.

Show-Ling Shyng (SL)

Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA. Electronic address: shyngs@ohsu.edu.

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Classifications MeSH