Retrospective Study on Ganglionic and Nerve Block Series as Therapeutic Option for Chronic Pain Patients with Refractory Neuropathic Pain.
Journal
Pain research & management
ISSN: 1918-1523
Titre abrégé: Pain Res Manag
Pays: United States
ID NLM: 9612504
Informations de publication
Date de publication:
2020
2020
Historique:
received:
22
04
2020
revised:
03
06
2020
accepted:
13
06
2020
entrez:
11
8
2020
pubmed:
11
8
2020
medline:
24
11
2020
Statut:
epublish
Résumé
Current recommendations controversially discuss local infiltration techniques as specific treatment for refractory pain syndromes. Evidence of effectiveness remains inconclusive and local infiltration series are discussed as a therapeutic option in patients not responding to standard therapy. The aim of this study was to investigate the effectiveness of infiltration series with techniques such as sphenopalatine ganglion (SPG) block and ganglionic local opioid analgesia (GLOA) for the treatment of neuropathic pain in the head and neck area in a selected patient group. In a retrospective clinical study, 4960 cases presenting to our university hospital outpatient pain clinic between 2009 and 2016 were screened. Altogether, 83 patients with neuropathic pain syndromes receiving local infiltration series were included. Numeric rating scale (NRS) scores before, during, and after infiltration series, comorbidity, and psychological assessment were evaluated. Maximum NRS before infiltration series was median 9 (IQR 8-10). During infiltration series, maximum NRS was reduced by mean 3.2 points (SD 3.3, This study suggests a beneficial effect of local infiltration series as a treatment option for refractory neuropathic pain syndromes in the context of a multimodal approach. This effect is both significant and clinically relevant and therefore highlights the need for further randomized controlled trials.
Identifiants
pubmed: 32774567
doi: 10.1155/2020/6042941
pmc: PMC7399767
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6042941Informations de copyright
Copyright © 2020 J. D. Gerken et al.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest regarding the publication of this paper.
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