A preliminary study of relationship among the degree of internal carotid artery stenosis, wall shear stress on MR angiography and
FDG
PET
carotid artery stenosis
computational fluid dynamics
wall shear stress
Journal
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
14
04
2020
accepted:
18
07
2020
pubmed:
4
8
2020
medline:
13
4
2022
entrez:
4
8
2020
Statut:
ppublish
Résumé
This preliminary study was undertaken to evaluate relationship among the degree of internal carotid artery (ICA) stenosis, wall shear stress (WSS) by computational fluid dynamics (CFD) on magnetic resonance angiography (MRA) and A total of 40 carotid arteries in 20 patients with carotid atherosclerotic disease were examined with MRA and Atherosclerotic risk factors did not affect imaging findings. There were significant correlations between WSSmax and degree of ICA stenosis (ρ = .81, P < .001), WSSmax and TBRmax (ρ = .64, P < .001), and TBRmax and degree of ICA stenosis (ρ = .50, P = .001). These preliminary results indicate that there may be significant correlations among the degree of ICA stenosis, WSSmax and TBRmax in patients with carotid artery stenosis.
Sections du résumé
BACKGROUND
This preliminary study was undertaken to evaluate relationship among the degree of internal carotid artery (ICA) stenosis, wall shear stress (WSS) by computational fluid dynamics (CFD) on magnetic resonance angiography (MRA) and
METHODS
A total of 40 carotid arteries in 20 patients with carotid atherosclerotic disease were examined with MRA and
RESULTS
Atherosclerotic risk factors did not affect imaging findings. There were significant correlations between WSSmax and degree of ICA stenosis (ρ = .81, P < .001), WSSmax and TBRmax (ρ = .64, P < .001), and TBRmax and degree of ICA stenosis (ρ = .50, P = .001).
CONCLUSIONS
These preliminary results indicate that there may be significant correlations among the degree of ICA stenosis, WSSmax and TBRmax in patients with carotid artery stenosis.
Identifiants
pubmed: 32743752
doi: 10.1007/s12350-020-02300-3
pii: 10.1007/s12350-020-02300-3
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
569-577Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020. American Society of Nuclear Cardiology.
Références
Barrett KM, Brott TG. Stroke caused by extracranial disease. Circ Res 2017;120:496-501.
pubmed: 28154099
Barnett HJ, Taylor DW, Eliasziw M, Fox AJ, Ferguson GG, Haynes RB, et al. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 1998;339:1415-25.
pubmed: 9811916
Rothwell PM, Gutnikov SA, Warlow CP. Reanalysis of the final results of the European Carotid Surgery Trial. Stroke 2003;34:514-23.
pubmed: 12574569
Millon A, Mathevet JL, Boussel L, Faries PL, Fayad ZA, Douek PC, et al. High-resolution magnetic resonance imaging of carotid atherosclerosis identifies vulnerable carotid plaques. J Vasc Surg 2013;57:1046-51.
pubmed: 23375613
Puppini G, Furlan F, Cirota N, Veraldi G, Piubello Q, Montemezzi S, et al. Characterisation of carotid atherosclerotic plaque: Comparison between magnetic resonance imaging and histology. Radiol Med 2006;111:921-30.
pubmed: 17021689
Takaya N, Yuan C, Chu B, Saam T, Underhill H, Cai J, et al. Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: A prospective assessment with MRI—initial results. Stroke 2006;37:818-23.
pubmed: 16469957
Zavodni AE, Wasserman BA, McClelland RL, Gomes AS, Folsom AR, Polak JF, et al. Carotid artery plaque morphology and composition in relation to incident cardiovascular events: The Multi-Ethnic Study of Atherosclerosis (MESA). Radiology 2014;271:381-9.
pubmed: 24592924
Sun J, Zhao XQ, Balu N, Neradilek MB, Isquith DA, Yamada K, et al. Carotid plaque lipid content and fibrous cap status predict systemic cardiovascular outcomes: The MRI substudy in AIM-HIGH. JACC Cardiovasc Imaging 2017;10:241-9.
pubmed: 28279371
pmcid: 5347460
McKenney-Drake ML, Moghbel MC, Paydary K, Alloosh M, Houshmand S, Moe S, et al.
pubmed: 29978245
pmcid: 6182398
Libby P. Inflammation in atherosclerosis. Nature 2002;420:868-74.
Tawakol A, Migrino RQ, Bashian GG, Bedri S, Vermylen D, Cury RC, et al. In vivo
pubmed: 17084256
Marnane M, Merwick A, Sheehan OC, Hannon N, Foran P, Grant T, et al. Carotid plaque inflammation on
pubmed: 22461139
Gharahi H, Zambrano BA, Zhu DC, DeMarco JK, Baek S. Computational fluid dynamic simulation of human carotid artery bifurcation based on anatomy and volumetric blood flow rate measured with magnetic resonance imaging. Int J Adv Eng Sci Appl Math 2016;8:40-60.
pubmed: 27546999
pmcid: 4987097
Cicha I, Wörner A, Urschel K, Beronov K, Goppelt-Struebe M, Verhoeven E, et al. Carotid plaque vulnerability: A positive feedback between hemodynamic and biochemical mechanisms. Stroke 2011;42:3502-10.
pubmed: 21998063
Tuenter A, Selwaness M, Arias Lorza A, Schuurbiers JCH, Speelman L, Cibis M, et al. High shear stress relates to intraplaque haemorrhage in asymptomatic carotid plaques. Atherosclerosis 2016;251:348-54.
pubmed: 27263078
Samady H, Eshtehardi P, McDaniel MC, Suo J, Dhawan SS, Maynard C, et al. Coronary artery wall shear stress is associated with progression and transformation of atherosclerotic plaque and arterial remodeling in patients with coronary artery disease. Circulation 2011;124:779-88.
pubmed: 21788584
Konishi T, Norikane T, Yamamoto Y, Fujimoto K, Takami Y, Mitamura K, et al. The potential relationship between
North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991;325:445-53.
Zarins CK, Zatina MA, Giddens DP, Ku DN, Glagov S. Shear stress regulation of artery lumen diameter in experimental atherogenesis. J Vasc Surg 1987;5:413-20.
pubmed: 3509594
Murray CD. The physiological principle of minimum work: A reply. J Gen Physiol 1931;14:445.
pubmed: 19872596
pmcid: 2141121
Font MA, Fernandez A, Carvajal A, Gamez C, Badimon L, Slevin M, et al. Imaging of early inflammation in low-to-moderate carotid stenosis by 18-FDG-PET. Front Biosci (Landmark Ed) 2009;14:3352-60.
Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, et al. Increased microvascularization and vessel permeability associate with active inflammation in human atheromata. Circ Cardiovasc Imaging 2014;7:920-9.
pubmed: 25170063
pmcid: 4237630
Honda A, Tahara N, Nitta Y, Tahara A, Igata S, Bekki M, et al. Vascular inflammation evaluated by [
pubmed: 27386941
Figueroa AL, Subramanian SS, Cury RC, Truong QA, Gardecki JA, Tearney GJ, et al. Distribution of inflammation within carotid atherosclerotic plaques with high-risk morphological features: A comparison between positron emission tomography activity, plaque morphology, and histopathology. Circ Cardiovasc Imaging 2012;5:69--77.
pubmed: 22038986
Reeps C, Essler M, Pelisek J, Seidl S, Eckstein HH, Krause BJ. Increased
pubmed: 18572354
Vesey AT, Jenkins WS, Irkle A, Moss A, Sng G, Forsythe RO, et al.
pubmed: 28292859
pmcid: 5367506
Pan S. Molecular mechanisms responsible for the atheroprotective effects of laminar shear stress. Antioxid Redox Signal 2009;11:1669-82.
pubmed: 19309258
pmcid: 2842586
Dolan JM, Meng H, Singh S, Paluch R, Kolega J. High fluid shear stress and spatial shear stress gradients affect endothelial proliferation, survival, and alignment. Ann Biomed Eng 2011;39:1620--31.
pubmed: 21312062
pmcid: 4809045
Giannopoulos AA, Antoniadis AP, Croce K, Chatzizisis YS. Erosion of thin-cap fibroatheroma in an area of low endothelial shear stress: Anatomy and local hemodynamic environment dictate outcomes. JACC Cardiovasc Interv 2016;9:e77-8.
pubmed: 27017369
Xu XY, Borghi A, Nchimi A, Leung J, Gomez P, Cheng Z, et al. High levels of 18F-FDG uptake in aortic aneurysm wall are associated with high wall stress. Eur J Vasc Endovasc Surg 2010;39:295-301.
pubmed: 19926315
Jia Q, Liu H, Li Y, Wang X, Jia J, Li Y. Combination of magnetic resonance angiography and computational fluid dynamics may predict the risk of stroke in patients with asymptomatic carotid plaques. Med Sci Monit 2017;23:479-88.
pubmed: 28126983
pmcid: 5292986
Peng C, Wang X, Xian Z, Liu X, Huang W, Xu P, et al. The impact of the geometric characteristics on the hemodynamics in the stenotic coronary artery. PLoS ONE 2016;11:e0157490.
pubmed: 27310014
pmcid: 4911169
Schirmer CM, Malek AM. Computational fluid dynamic characterization of carotid bifurcation stenosis in patient-based geometries. Brain Behav 2012;2:42-52.
pubmed: 22574273
pmcid: 3343298
Li CH, Gao BL, Wang JW, Liu JF, Li H, Yang ST. Hemodynamic factors affecting carotid sinus atherosclerotic stenosis. World Neurosurg 2019;121:e262-76.
pubmed: 30261386
Bhatia R, Vashisth S, Saini R. Wall shear stress analysis in stenosed carotid arteries with different shapes of plaque. Intl J Comput Appl 2016;145:9-12.
Shaikh S, Welch A, Ramalingam SL, Murray A, Wilson HM, McKiddie F, et al. Comparison of fluorodeoxyglucose uptake in symptomatic carotid artery and stable femoral artery plaques. Br J Surg 2014;101:363-70.
pubmed: 24536009
Elhfnawy AM, Heuschmann PU, Pham M, Volkmann J, Fluri F. Stenosis length and degree interact with the risk of cerebrovascular events related to internal carotid artery stenosis. Front Neurol 2019;10:317.
pubmed: 31024420
pmcid: 6465418
Lee JM, Choi G, Koo BK, Hwang D, Park J, Zhang J, et al. Identification of high-risk plaques destined to cause acute coronary syndrome using coronary computed tomographic angiography and computational fluid dynamics. JACC Cardiovasc Imaging 2019;12:1032-43.
pubmed: 29550316
Evans NR, Tarkin JM, Chowdhury MM, Le EPV, Coughlin PA, Rudd JHF, et al. Dual-tracer positron-emission tomography for identification of culprit carotid plaques and pathophysiology in vivo. Circ Cardiovasc Imaging 2020;13:e009539.
pubmed: 32164454
Eshtehardi P, Brown AJ, Bhargava A, et al. High wall shear stress and high-risk plaque: An emerging concept. Int J Cardiovasc Imaging 2017;33:1089-99.
pubmed: 28074425
pmcid: 5496586
Tahara N, Kai H, Ishibashi M, Nakaura H, Kaida H, Baba K, et al. Simvastatin attenuates plaque inflammation: Evaluation by fluorodeoxyglucose positron emission tomography. J Am Coll Cardiol 2006;48:1825-31.
pubmed: 17084257
Kimura H, Hayashi K, Taniguchi M, Hosoda K, Fujita A, Seta T, et al. Detection of hemodynamic characteristics before growth in growing cerebral aneurysms by analyzing time-of-flight magnetic resonance angiography images alone: Preliminary results. World Neurosurg 2019;122:e1439-48.
pubmed: 30465954