Liver function tests in dogs with congenital portosystemic shunts and their potential to determine persistent shunting after surgical attenuation.

Animals Dog Diseases / diagnosis Dogs Liver Function Tests / veterinary Vascular Fistula / diagnosis
Blood test Liver dysfunction Vascular anomaly

Journal

Veterinary journal (London, England : 1997)
ISSN: 1532-2971
Titre abrégé: Vet J
Pays: England
ID NLM: 9706281

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 05 11 2019
revised: 24 05 2020
accepted: 29 05 2020
entrez: 4 8 2020
pubmed: 4 8 2020
medline: 12 1 2021
Statut: ppublish

Résumé

Portosystemic shunts (PSS) are congenital or acquired vascular anomalies that cause blood to bypass the liver. Liver function tests, such as fasting ammonia, ammonia tolerance test, and (paired) serum bile acids, are reliable for the diagnosis of PSS in dogs. Surgical attenuation is a common treatment for congenital PSS. Following surgical attenuation, it is useful to evaluate shunt closure. In this critical review, the ability of liver function tests to determine the presence and degree of residual shunting following surgical attenuation of canine PSS is discussed. Despite the availability of several liver function tests, a single rapid, simple, cost-effective, sensitive and specific test to evaluate surgical attenuation of PSS is not available.

Identifiants

DOI: 10.1016/j.tvjl.2020.105478 PMID: 32741493
pubmed: 32741493
pii: S1090-0233(20)30055-1
doi: 10.1016/j.tvjl.2020.105478
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

105478

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Nausikaa Devriendt (N)

Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: nausikaa.devriendt@ugent.be.

Gonçalo Serrano (G)

Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.

Dominique Paepe (D)

Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.

Hilde de Rooster (H)

Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.

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Classifications MeSH

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