HPV-related carcinoma of the oropharynx: challenges on small biopsy specimens.
Adult
Biomarkers, Tumor
/ immunology
Biopsy, Needle
/ methods
Cyclin-Dependent Kinase Inhibitor p16
/ immunology
DNA, Viral
/ genetics
Female
Human papillomavirus 16
/ genetics
Humans
Immunohistochemistry
In Situ Hybridization
Male
Middle Aged
Oropharyngeal Neoplasms
/ complications
Oropharynx
/ pathology
Papillomavirus Infections
/ complications
Polymerase Chain Reaction
Squamous Cell Carcinoma of Head and Neck
/ complications
HPV
Human papillomavirus
Oropharynx
Squamous cell carcinoma
p16
Journal
Journal of the American Society of Cytopathology
ISSN: 2213-2945
Titre abrégé: J Am Soc Cytopathol
Pays: United States
ID NLM: 101613234
Informations de publication
Date de publication:
Historique:
received:
21
04
2020
revised:
11
06
2020
accepted:
12
06
2020
pubmed:
12
7
2020
medline:
28
8
2021
entrez:
12
7
2020
Statut:
ppublish
Résumé
Human papillomavirus (HPV)-related oropharyngeal carcinoma can morphologically mimic many processes from benign to malignant and lead pathologists to incorrectly diagnose them and/or use inappropriate diagnostic terminology. Recognition of HPV-related oropharyngeal carcinoma and its variants is critical for appropriate prognostic and therapeutic considerations in small biopsy material. Various pitfalls in diagnosing these tumors on limited biopsies are discussed herein.
Identifiants
pubmed: 32651129
pii: S2213-2945(20)30108-3
doi: 10.1016/j.jasc.2020.06.001
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
CDKN2A protein, human
0
Cyclin-Dependent Kinase Inhibitor p16
0
DNA, Viral
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
359-368Informations de copyright
Copyright © 2020 American Society of Cytopathology. Published by Elsevier Inc. All rights reserved.