Electrocardiographic voltage criteria in patients with hypertrophic cardiomyopathy.
Action Potentials
Adult
Aged
Cardiomyopathy, Hypertrophic
/ diagnosis
Electrocardiography
Female
Heart Conduction System
/ physiopathology
Heart Rate
Humans
Hypertrophy, Left Ventricular
/ diagnosis
Magnetic Resonance Imaging, Cine
Male
Middle Aged
Predictive Value of Tests
Reproducibility of Results
Retrospective Studies
Ventricular Function, Left
Ventricular Remodeling
Journal
Journal of cardiovascular medicine (Hagerstown, Md.)
ISSN: 1558-2035
Titre abrégé: J Cardiovasc Med (Hagerstown)
Pays: United States
ID NLM: 101259752
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
pubmed:
9
7
2020
medline:
8
6
2021
entrez:
9
7
2020
Statut:
ppublish
Résumé
Several ECG voltage criteria have been proposed for the diagnosis of left ventricular hypertrophy (LVH). Notably, ECG criteria have been historically validated in concentric LVH but not in hypertrophic cardiomyopathy (HCM), wherein the hypertrophy pattern is typically asymmetric. The aim of our study was to evaluate the performance of ECG voltage criteria for LVH diagnosis in the HCM population. The electrocardiograms of 92 HCM patients and 41 sex- and age-matched controls were evaluated with the most frequently used ECG voltage criteria for LVH diagnosis. Cardiac magnetic resonance (MRI) was performed in HCM and controls in order to quantify LVH and its distribution. In the HCM population, the maximal diagnostic accuracy was achieved by Amplitude total and Amplitude total product criteria (58% for both), while the Cornell Voltage best performed in septal HCM (62%), the Sokolov in aVL and Gubner criteria in apical HCM (79% for both) and the Cornell Voltage and Product in anterior HCM (86% for both). All the ECG voltage criteria showed a poor correlation with left ventricular mass and maximal thickness measured by cardiac MRI. In our study, only a few ECG voltage criteria used for the detection of LVH in clinical practice showed an acceptable performance in the HCM population. Further studies are needed to clarify the role of ECG for LVH detection in HCM patients.
Sections du résumé
BACKGROUND
BACKGROUND
Several ECG voltage criteria have been proposed for the diagnosis of left ventricular hypertrophy (LVH). Notably, ECG criteria have been historically validated in concentric LVH but not in hypertrophic cardiomyopathy (HCM), wherein the hypertrophy pattern is typically asymmetric.
OBJECTIVES
OBJECTIVE
The aim of our study was to evaluate the performance of ECG voltage criteria for LVH diagnosis in the HCM population.
MATERIAL AND METHODS
METHODS
The electrocardiograms of 92 HCM patients and 41 sex- and age-matched controls were evaluated with the most frequently used ECG voltage criteria for LVH diagnosis. Cardiac magnetic resonance (MRI) was performed in HCM and controls in order to quantify LVH and its distribution.
RESULTS
RESULTS
In the HCM population, the maximal diagnostic accuracy was achieved by Amplitude total and Amplitude total product criteria (58% for both), while the Cornell Voltage best performed in septal HCM (62%), the Sokolov in aVL and Gubner criteria in apical HCM (79% for both) and the Cornell Voltage and Product in anterior HCM (86% for both). All the ECG voltage criteria showed a poor correlation with left ventricular mass and maximal thickness measured by cardiac MRI.
CONCLUSIONS
CONCLUSIONS
In our study, only a few ECG voltage criteria used for the detection of LVH in clinical practice showed an acceptable performance in the HCM population. Further studies are needed to clarify the role of ECG for LVH detection in HCM patients.
Identifiants
pubmed: 32639329
doi: 10.2459/JCM.0000000000001034
pii: 01244665-202009000-00013
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
696-703Références
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