The p.P888L SAP97 polymorphism increases the transient outward current (I
Action Potentials
/ physiology
Animals
Arrhythmias, Cardiac
/ genetics
CHO Cells
Calcium-Calmodulin-Dependent Protein Kinase Type 2
/ genetics
Cell Line
Cricetulus
Discs Large Homolog 1 Protein
/ genetics
Humans
Kv1.5 Potassium Channel
/ physiology
Mice
Myocytes, Cardiac
/ metabolism
Patch-Clamp Techniques
Phosphorylation
/ physiology
Polymorphism, Single Nucleotide
/ genetics
Shal Potassium Channels
/ physiology
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
01 07 2020
01 07 2020
Historique:
received:
26
12
2019
accepted:
01
06
2020
entrez:
3
7
2020
pubmed:
3
7
2020
medline:
15
12
2020
Statut:
epublish
Résumé
Synapse-Associated Protein 97 (SAP97) is an anchoring protein that in cardiomyocytes targets to the membrane and regulates Na
Identifiants
pubmed: 32612162
doi: 10.1038/s41598-020-67109-z
pii: 10.1038/s41598-020-67109-z
pmc: PMC7329876
doi:
Substances chimiques
DLG1 protein, human
0
Discs Large Homolog 1 Protein
0
Kv1.5 Potassium Channel
0
Shal Potassium Channels
0
Calcium-Calmodulin-Dependent Protein Kinase Type 2
EC 2.7.11.17
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
10707Investigateurs
Joaquín J Alonso-Martín
(JJ)
Fernando Arribas
(F)
Felipe Atienza
(F)
Antonio Hernández-Madrid
(A)
José Luis López-Sendón
(JL)
Julián Pérez-Villacastín
(J)
Jorge Toquero
(J)
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