The Effect of Low-Carbohydrate Diet on Macrovascular and Microvascular Endothelial Function is Not Affected by the Provision of Caloric Restriction in Women with Obesity: A Randomized Study.
cardiovascular risks
conduit artery
hypocaloric
isocaloric
low-carbohydrate diet
microvasculature
nitric oxide
obesity
primary prevention
women health
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
02 Jun 2020
02 Jun 2020
Historique:
received:
18
04
2020
revised:
21
05
2020
accepted:
29
05
2020
entrez:
6
6
2020
pubmed:
6
6
2020
medline:
25
2
2021
Statut:
epublish
Résumé
Obesity impairs both macro- and microvascular endothelial function due to decreased bioavailability of nitric oxide. Current evidence on the effect of low-carbohydrate (LC) diet on endothelial function is conflicting and confounded by the provision of caloric restriction (CR). We tested the hypothesis that LC without CR diet, but not LC with CR diet, would improve macro- and microvascular endothelial function in women with obesity. Twenty-one healthy women with obesity (age: 33 ± 2 years, body mass index: 33.0 ± 0.6 kg/m
Identifiants
pubmed: 32498328
pii: nu12061649
doi: 10.3390/nu12061649
pmc: PMC7352173
pii:
doi:
Substances chimiques
Nitric Oxide
31C4KY9ESH
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NCATS NIH HHS
ID : UL1TR002003
Pays : United States
Organisme : NHLBI NIH HHS
ID : HL095701
Pays : United States
Organisme : NHLBI NIH HHS
ID : K99 HL140049
Pays : United States
Organisme : NHLBI NIH HHS
ID : R00 HL140049
Pays : United States
Organisme : American Heart Association
ID : 20POST35120466
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health and the American Heart Association.
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