Aromatic Stacking Facilitated Self-Assembly of Ultrashort Ionic Complementary Peptide Sequence: β-Sheet Nanofibers with Remarkable Gelation and Interfacial Properties.

Hydrogels Hydrogen Bonding Nanofibers Peptides Protein Conformation, beta-Strand

Journal

Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849

Informations de publication

Date de publication:
13 07 2020
Historique:
pubmed: 14 5 2020
medline: 22 6 2021
entrez: 14 5 2020
Statut: ppublish

Résumé

Understanding peptide self-assembly mechanisms and stability of the formed assemblies is crucial for the development of functional nanomaterials. Herein, we have adopted a rational design approach to demonstrate how a minimal structural modification to a nonassembling ultrashort ionic self-complementary tetrapeptide

Identifiants

DOI: 10.1021/acs.biomac.0c00366 PMID: 32401499
pubmed: 32401499
doi: 10.1021/acs.biomac.0c00366
doi:

Substances chimiques

Hydrogels 0
Peptides 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2670-2680

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Auteurs

Jacek K Wychowaniec (JK)

School of Materials, University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.
Manchester Institute of Biotechnology, Oxford Road, Manchester M13 9PL, United Kingdom.
School of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland.
ORCID: 0000-0002-6597-5242

Ronak Patel (R)

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.

James Leach (J)

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.

Rachel Mathomes (R)

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.

Vikesh Chhabria (V)

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.

Yogita Patil-Sen (Y)

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.

Araida Hidalgo-Bastida (A)

Centre for Biosciences, Department of Life Science, Manchester Metropolitan University, Manchester, M1 5GD, United Kingdom.
Centre for Musculoskeletal Science and Sports Medicine, Manchester Metropolitan University, Manchester, M1 5GD, United Kingdom.
Centre for Advance Materials and Surface Engineering, Manchester Metropolitan University, Manchester, M1 5GD, United Kingdom.

Robert T Forbes (RT)

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.

Joseph M Hayes (JM)

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.
ORCID: 0000-0002-7745-9616

Mohamed A Elsawy (MA)

School of Materials, University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.
Manchester Institute of Biotechnology, Oxford Road, Manchester M13 9PL, United Kingdom.
School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom.
Leicester Institute of Pharmaceutical Innovation, Leicester School of Pharmacy, De Monfort University, The Gateway, Leicester LE1 9BH, United Kingdom.
ORCID: 0000-0003-3964-2150

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Classifications MeSH

Recherchemedicale.com › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Aromatic Stacking Facilitated Self-Assembly of...
Recherchemedicale.com › Phénomènes chimiques › Liaison hydrogène › Aromatic Stacking Facilitated Self-Assembly of...
Recherchemedicale.com › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanofibres › Aromatic Stacking Facilitated Self-Assembly of...
Recherchemedicale.com › Acides aminés, peptides et protéines › Peptides › Aromatic Stacking Facilitated Self-Assembly of...
Recherchemedicale.com › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure secondaire des protéines › Structure en brin bêta › Aromatic Stacking Facilitated Self-Assembly of...